Immune Checkpoint Inhibitors

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DBCAT005176Pharmacologic class

Immune checkpoint inhibitors work by blocking checkpoint proteins from binding with their partner proteins. This prevents the “off” signal from being sent, allowing the T cells to kill cancer cells. A DrugBank category of 67 drugs. 22 of them are approved.

Also known as
Checkpoint Inhibitors · ICIs · Antineoplastic immune checkpoint inhibitors
Drugs

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What you can answer from here — as of May 26, 2021

67DrugsEach linked to its full drug card
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39Drug targetsEvery drug–target pair in the class, with bond type
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238Marketed productsAcross the regions we cover, with dosage forms and routes
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6Routes of administrationHow the drugs in this class are given
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Which targets do Immune Checkpoint Inhibitors share, and which companies have late-stage candidates in this class?

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