Coronary Revascularization (DBCOND0048469)
Identifiers
- Synonyms
- Repeat coronary revascularization / Coronary revascularization / Coronary revascularisation
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Cangrelor A P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST).- P2Y purinoceptor 12target
Colchicine An alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events.- Tubulin beta chaintarget
- Cytochrome P450 3A4enzyme
- ATP-dependent translocase ABCB1transporter
- Cytochrome P450 2B6enzyme
- Cytochrome P450 2C8enzyme
- Cytochrome P450 2E1enzyme
- Albumincarrier
Evolocumab A PCSK9 (proprotein convertase subtilisin kexin type 9) inhibitor antibody used as an adjunct to LDL cholesterol reducing therapies, aiding in the prevention of cardiovascular events and cardiovascular revascularization procedures.Lovastatin An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.- 3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
- Cytochrome P450 3A4enzyme
- Cytochrome P450 2C8enzyme
- Integrin alpha-Ltarget
- Histone deacetylase 2target
- Serum paraoxonase/lactonase 3enzyme
- ATP-dependent translocase ABCB1transporter
- Solute carrier organic anion transporter family member 1A2transporter
- Solute carrier organic anion transporter family member 1B1transporter
- UDP-glucuronosyltransferase 1A1enzyme
- UDP-glucuronosyltransferase 1A3enzyme
- UDP-glucuronosyltransferase 2B7enzyme
- ATP-binding cassette sub-family C member 2transporter
- Bile salt export pumptransporter
- Albumincarrier
- Cytochrome P450 2C19enzyme
- Solute carrier organic anion transporter family member 2B1transporter
- Solute carrier organic anion transporter family member 1B3transporter
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT02425345 Women's Health Initiative Strong and Healthy Study No drug interventions prevention Not Available active_not_recruiting NCT02880605 Validation of Chinese Version Appropriate Use Criteria for Coronary Revascularization No drug interventions Not Available Not Available completed NCT03229941 Transfusion Trigger After Operations in High Cardiac Risk Patients No drug interventions other Not Available completed NCT01190904 Hormones and Sexual Function Predict Outcomes in Revascularized Men With Diabetes No drug interventions Not Available Not Available completed NCT05284747 EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction treatment 4 active_not_recruiting NCT06583161 Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15) No drug interventions Not Available Not Available completed NCT06520215 Correlation Hand Grip Strength and Walking Distance in Elderly No drug interventions Not Available Not Available not_yet_recruiting NCT03068858 Real-time Feedback of SYNTAX Score Category During Coronary Angiographies to Improve Appropriateness of Coronary Revascularization for Patients With Stable Coronary Artery Diseases: a Before-and-after Controlled Study No drug interventions treatment Not Available completed