Central Nervous System Infections (DBCOND0055550)
Identifiers
- Synonyms
- Central Nervous System Infection / Infectious disease of central nervous system (disorder) / Central nervous system infection NOS
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Amikacin An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.Ceftazidime An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others.- Solute carrier family 22 member 6transporter
- Peptidoglycan synthase FtsItarget
- Penicillin-binding protein 1Atarget
- Penicillin-binding protein 1Btarget
- Penicillin-binding protein 2target
- Albumincarrier
- Beta-lactamase Toho-1target
Gentamicin An aminoglycoside used to treat a wide variety of aerobic infections in the body.- 30S ribosomal protein S12target
- 16S ribosomal RNAtarget
- NH(3)-dependent NAD(+) synthetasetarget
- Dihydrofolate reductasetarget
- 23S ribosomal RNAtarget
- Bacterial outer membranetarget
- Cytoplasmic membranetarget
- Low-density lipoprotein receptor-related protein 2transporter
- Solute carrier family 22 member 2transporter
- ATP-binding cassette sub-family C member 2transporter
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT01438879 Lymphocytic Herpesviruses and Cerebrospinal Fluid Polymerase Chain Reaction (PCR) No drug interventions Not Available Not Available unknown_status NCT03960905 A Study the Population Pharmacokinetics of Children of Infectious Disease in Central Nervous System No drug interventions Not Available Not Available unknown_status NCT00172393 Long Term Outcomes of EV71 CNS Infection No drug interventions Not Available Not Available unknown_status NCT01520597 National Study on Listeriosis and Listeria No drug interventions Not Available Not Available completed NCT04737785 Central Nervous System Disorders Following Hematopoietic Stem Cell Transplantation No drug interventions Not Available Not Available completed NCT05887037 Economic Impact of mNGS on Diagnosis of Post-neurosurgical Central Nervous System Infection No drug interventions diagnostic Not Available recruiting NCT03418441 Central Nervous System Infections in Denmark No drug interventions Not Available Not Available recruiting NCT04796935 A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control No drug interventions other Not Available completed NCT01431326 Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care - Alfentanil
- Amikacin
- Aminocaproic acid
- Bosentan
- Cefepime
- Cidofovir
- Ciprofloxacin
- Clozapine
- Fosfomycin
- Haloperidol
- Labetalol
- Lurasidone
- Methylprednisolone
- Molindone
- Nafcillin
- Nifedipine
- Oxycodone
- Pentobarbital
- Piperacillin
- Rocuronium
- Sevelamer
- Spironolactone
- Tazobactam
- Tobramycin
- Tranexamic acid
- Vancomycin
- Vecuronium
- Warfarin
- Ziprasidone
- Zolpidem
Not Available Not Available completed NCT06412523 Device-related Central Nervous System Infections in Adult Intensive Care Units in Brazil No drug interventions Not Available Not Available active_not_recruiting NCT04229511 Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized Patients No drug interventions Not Available Not Available unknown_status NCT06358209 Safety and Efficacy of Ventricular Irrigation for Ventriculitis No drug interventions treatment Not Available not_yet_recruiting NCT02334670 Vietnam Cryptococcal Retention in Care Study Version 1.0 No drug interventions Not Available Not Available unknown_status NCT06412549 Effect of a Bundle of Interventions on the Outcomes of Patients With Intracranial Devices (ICP Monitor e EVD) No drug interventions supportive_care Not Available not_yet_recruiting NCT02506686 Meropenem Penetration Across BBB in Patients With CNS Infection and Optimization of Meropenem Treatment No drug interventions treatment 4 completed NCT06418048 INfectious DIsease REgistry BIObank No drug interventions Not Available Not Available recruiting NCT02017665 Singapore Neurologic Infections Program No drug interventions Not Available Not Available unknown_status NCT03776994 Venezuelan Equine Encephalitis Monovalent Virus-Like Particle Vaccine No drug interventions prevention 1 unknown_status