NCT04721223
JAB-3068 Activity in Adult Patients With Advanced Solid Tumors treatment 1 / 2 completed NCT04977453
GI-101 As a Single Agent or in Combination with Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors treatment 1 / 2 recruiting NCT05078047
Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO No drug interventions treatment 3 recruiting NCT05208762
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors treatment 1 recruiting NCT05319730
A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B) treatment 1 / 2 recruiting NCT05902988
A Phase I/II Study of VLS-1488 in Subjects with Advanced Cancer No drug interventions treatment 1 / 2 recruiting NCT06022861
A Study to Compare the Efficacy and Safety of LY01015 and Opdivo® Combined Respectively With Chemotherapy in Advanced or Metastatic Esophageal Squamous Cell Carcinoma treatment 3 recruiting NCT06510660
Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC treatment 2 recruiting NCT06549816
A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors treatment 1 recruiting NCT06588335
BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT06601309
Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC treatment 2 recruiting NCT06602843
Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy No drug interventions treatment Not Available recruiting NCT06490003
Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma Not Available Not Available recruiting NCT05980403
Prediction of Lymph Node Status in Stage T1 Esophageal Squamous Cell Carcinoma（RENMIN-237） No drug interventions Not Available Not Available recruiting NCT03958890
A Clinical Trial Comparing HLX10 With Placebo Combined With Chemotherapy (Cisplatin + 5-fu) in the First-line Treatment of Locally Advanced/Metastatic Esophageal Squamous Cell Carcinoma (ESCC) treatment 3 active_not_recruiting NCT04666090
Carrelizumab, Chemotherapy and Apatinib in the Neoadjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma No drug interventions treatment 2 active_not_recruiting NCT06103890
Dynamic ctDNA Monitoring in Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma No drug interventions Not Available Not Available recruiting NCT02645864
Apatinib and Irinotecan Combination Treatment in Esophageal Squamous Cell Carcinoma treatment 1 completed NCT06225921
Neoadjuvant Adebrelimab With Dalpiciclib for Resectable Esophageal Squamous Cell Carcinomas treatment 1 recruiting NCT06241079
Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma No drug interventions Not Available Not Available completed NCT04764643
The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy diagnostic Not Available completed NCT05659251
Serplulimab Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma treatment 2 recruiting NCT05552651
Envafolimab Combined With Chemotherapy in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT05591053
Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans No drug interventions diagnostic Not Available recruiting NCT03964753
Neoadjuvant Therapy With Nab-paclitaxel and Cisplatin for Locally Advanced Esophageal Squamous Cell Carcinoma treatment 2 recruiting NCT01598077
A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer treatment 1 completed NCT04868877
Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination treatment 1 / 2 recruiting NCT06190847
Oral Microbiome is Associated With the Response to Chemoradiotherapy in Initial Inoperable Patients With Esophageal Squamous Cell Cancer No drug interventions Not Available Not Available recruiting NCT03792347
Preoperative Anti-PD-1 Antibody Combined With Chemoradiotherapy for Locally Advanced Squamous Cell Carcinoma of Esophagus treatment 1 completed NCT06401447
TPF Concurrent Chemo-radiotherapy Plus Immunotherapy for Local Advanced Esophageal Squamous Cell Carcinoma No drug interventions treatment Not Available recruiting NCT02047305
Radiofrequency Ablation for Patients With Esophageal Squamous Cell Neoplasia No drug interventions treatment Not Available completed NCT04519905
Phase III Study of Concurrent Radiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESO-Shanghai 15) treatment Not Available recruiting NCT02094105
Endoscopic Screening on Esophageal Cancer No drug interventions prevention Not Available completed NCT04435197
Pre-Operative Pembrolizumab + Chemoradiation in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma treatment 2 completed NCT04177797
Toripalimab With Neoadjuvant Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT06303583
Neoadjuvant Chemoradiotherapy Followed by Sequential Immunotherapy for Thoracic Esophageal Squamous Cell Carcinoma treatment 1 / 2 enrolling_by_invitation NCT04880811
Afatinib Plus Toripalimab in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification treatment 2 unknown_status NCT05978193
Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma No drug interventions treatment 2 recruiting NCT06122493
Optimization of Treatment Strategy for Unresectable cN3 Esophageal Squamous Cell Carcinoma treatment 2 recruiting NCT06561178
Individualized Tumor-Informed CtDNA Analysis for Monitoring Postoperative Recurrence in ESCC (NEOCRTEC2401) No drug interventions Not Available Not Available recruiting NCT03160209
HIV and Other Risk Factors for Esophageal Squamous Cell Carcinoma in Malawi No drug interventions Not Available Not Available completed NCT06186609
PD-1 Inhibitor Combined With Radiotherapy for Elderly ESCC No drug interventions treatment 2 recruiting NCT03603756
SHR-1210 in Combination With Apatinib and Chemotherapy in Patients With Advanced Esophageal Squamous Cell Cancer treatment 2 unknown_status NCT04844385
Toripalimab Plus Neoadjuvant Chemotherapy Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT05394415
Chemoradiation Plus Tislelizumab for Conversion Therapy of Locally Nonresectable ESCC treatment 1 / 2 recruiting NCT03987815
Neoadjuvant Nivolumab for Operable Esophageal Carcinoma treatment 2 unknown_status NCT04244552
A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies treatment 1 terminated NCT03116152
Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment treatment 2 completed NCT05495152
Adjuvant Sintilimab for Locally Advanced Esophageal Squamous Cell Carcinoma treatment 3 active_not_recruiting NCT04481100
CCRT With Itraconazole in Locally Advanced Squamous Esophageal Cancer treatment 2 unknown_status NCT03377400
Definitive CCRT Combined With Durvalumab and Tremelimumab for Inoperable Esophageal Cancer treatment 2 unknown_status NCT04568200
Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Resectable Esophageal Squamous Cell Carcinoma treatment 2 completed NCT01740375
Role of Esophagectomy in Complete Responders to CCRT No drug interventions treatment 3 terminated NCT02844075
Preoperative Chemoradiotherapy and MK-3475 for Esophageal Squamous Cell Carcinoma (ACTS-29) treatment 2 completed NCT06468670
Short-course Radiotherapy Combined With Sintilimab for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT04060342
GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma treatment 1 terminated NCT05984342
Adjuvant Chemotherapy in Combination With Tislelizumab in Lymph Node-Positive Esophageal Squamous Cell Carcinoma treatment 1 recruiting NCT04936399
A Study of Participants With Squamous Cell Oesophageal Carcinoma Receiving Nivolumab as Part of an Early Access to Medicines Scheme (EAMS) Program in the United Kingdom Not Available Not Available completed NCT05561699
Sequential Preoperative Penpulimab Combined With Chemoradiotherapy(CRT) for Locally Advanced Esophageal Squamous Cell Cancer treatment Not Available not_yet_recruiting NCT02399306
Chemoradiotherapy With or Without Enteral Nutrition for Locally Advanced Thoracic Esophageal Carcinoma No drug interventions treatment 3 completed NCT04290806
Registry Platform Gastric/Esophageal Cancer (SAPHIR) No drug interventions Not Available Not Available recruiting NCT03660449
Moderately Hypofractionated Conformal Radiation Combined With S-1 for Esophageal Squamous Cell Carcinoma No drug interventions treatment 2 completed NCT04229849
Anrotenib Plus Toripalimab Versus Toripalimab in Patients With Advanced Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT01854749
S1 Combined With Cisplatin in Treatment of Recurrence/Metastasis of ESCC Open-label Single Center Phase II Clinical Study treatment 2 completed NCT05199649
Correlation Between the Efficacy of Neoadjuvant Chemotherapy Combined With Immunotherapy of Operable Thoracic Esophageal Squamous Cell Carcinoma and the Metabolites of Intestinal Flora screening Not Available unknown_status NCT02465736
Study of Docetaxel or Vinorelbine Plus Cisplatin in Neoadjuvant Chemoradiotherapy for Esophageal Cancer (NEOCRTEC308) treatment 3 active_not_recruiting NCT01822613
Study of Safety & Efficacy of the Combination of LJM716 & BYL719 in Patients With Previously Treated Esophageal Squamous Cell Carcinoma (ESCC) treatment 1 completed NCT04609813
Esophageal cAncer Screening Trial No drug interventions Not Available Not Available completed NCT04054518
Durvalumab as Maintenance Following Chemoradiation for Unresectable Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT05520619
Combination of Tislelizumab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-002) treatment 2 recruiting NCT05775419
Comparison of Chemoradiotherapy and Chemoradiotherapy Combined With Consolidation Chemotherapy for ESCC No drug interventions treatment Not Available recruiting NCT03474341
Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer No drug interventions Not Available Not Available unknown_status NCT06184841
HAIC Combined Sintilimab for Liver Metastasis From Esophageal Squamous Cell Carcinoma No drug interventions treatment 1 completed NCT05633641
Peripheral Blood Neoantigen Specific T Cells Predict the Efficacy of Immunotherapy for Esophageal Squamous Cell Carcinoma No drug interventions Not Available Not Available recruiting NCT03251417
Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell Carcinoma treatment 2 terminated NCT04543617
A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy treatment 3 active_not_recruiting NCT06491134
Liposomal Irinotecan With Cisplatin and Concurrent Radiotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma treatment 1 not_yet_recruiting NCT03748134
Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 ) treatment 3 completed NCT02976896
Apatinib for Esophageal Squamous Cell Cancer After the Failure of Standard Treatment treatment 2 completed NCT03817658
A Phase II Study of SHR-1210 vs Placebo as Consolidation Chemotherapy After Radical Concurrent Chemoradiotherapy in Locally Advanced ESCC treatment 2 unknown_status NCT04390958
Neoadjuvant Chemotherapy With Nab-paclitaxel Plus Cisplatin and Capecitabine for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT02490735
CIK in Treating Patients With Esophageal Cancer No drug interventions treatment 2 not_yet_recruiting NCT06388135
Serplulimab Combined With Nab-paclitaxel and Cisplatin in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma treatment 4 not_yet_recruiting NCT03857763
A Prospective Study of Apatinib Plus Concurrent Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT04275986
Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma No drug interventions treatment 2 unknown_status NCT06173986
Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer treatment 1 / 2 recruiting NCT02325986
Concurrent Radiotherapy and Weekly Chemotherapy of PF for Postoperative Locoregional Recurrence of Esophageal Cancer treatment 2 unknown_status NCT02647125
A Study of Comparing Huachansu Plus Thoracic RT Versus RT Alone For ESCC No drug interventions treatment 2 unknown_status NCT03206125
NCI UNC Project ESCC No drug interventions Not Available Not Available terminated NCT05317325
A Translational Study of Tumor Antigen-pulsed DC Vaccine for ESCC No drug interventions treatment 1 unknown_status NCT05919030
A Study of Chemoradiation in Combination With Tislelizumab as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma treatment 3 recruiting NCT04328948
A Randomized Controlled Trial Evaluating of Prophylactic Irradiation in CRT for cT1bN0M0 ESCC No drug interventions treatment 3 recruiting NCT01498757
Genome-wide Association Study No drug interventions Not Available Not Available withdrawn NCT06446726
Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT05603065
Tislelizumab With Chemotherapy or Radiation for Neoadjuvant Therapy of Esophageal Squamous Cell Carcinoma (TINES) treatment 4 active_not_recruiting NCT04009265
Study Compare Adjuvant Chemotherapy, Chemoradiotherapy and Surgery Alone for pN1-2(pT1b-3N1-2M0) Esophageal Carcinoma No drug interventions treatment 3 recruiting NCT06429865
Cytosponge in Surveillance After Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma No drug interventions diagnostic Not Available enrolling_by_invitation NCT06333665
PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy No drug interventions Not Available Not Available active_not_recruiting NCT06252974
Accurate Diagnosis of the Invasion Depth in ESCC by a Deep Neural Network Analysis of NBI Endoscopy Data No drug interventions Not Available Not Available not_yet_recruiting NCT03913182
Apatinib in the Treatment of Recurrence or Metastasis of Esophageal Cancer treatment 2 unknown_status NCT06190782
Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor No drug interventions treatment 3 recruiting NCT05028231
Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma: a Single Center, Prospective, Open, One Arm Exploratory Clinical Study No drug interventions Not Available Not Available recruiting NCT01831531
Study of S-1 in Combination With Radiotherapy in Esophageal Cancer No drug interventions treatment 2 completed NCT04807673
Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002) treatment 3 recruiting NCT05951127
Additional Consolidative Esophagectomy for the Patients With Oligometastatic Resectable ESCC No drug interventions treatment Not Available active_not_recruiting NCT04764227
Phase II Study of Postoperative Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESO- Shanghai 17) treatment 2 active_not_recruiting NCT04550260
Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC treatment 3 active_not_recruiting NCT06034860
Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types treatment 1 recruiting NCT05461794
Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma treatment 2 terminated NCT04699994
Prospective Trial to Evaluate the Safety and Efficacy to Treat Esophageal Cancer Using 5-FU, Oxaliplatin, and Docetaxel No drug interventions treatment 2 recruiting NCT05833594
Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs for Local Advanced Patients With Inoperable Esophageal Squamous Cell Carcinoma No drug interventions Not Available Not Available recruiting NCT06125262
Trajectory Analysis of NLR and Its Association With Efficacy of Immunochemotherapy in ESCC. No drug interventions Not Available Not Available recruiting NCT05265962
Decitabine Plus Penpulimab as Second-line Therapy for Advanced ESCC Treated With PD-1 Blockade treatment 2 not_yet_recruiting NCT01402180
Chemoradiation With or Without Nimotuzumab in Treating Esophageal Cancer Patients Who Suffer With Recurrence in Regional Lymph Nodes After Esophagectomy treatment 2 / 3 unknown_status NCT04380480
Percutaneous Endoscopic Gastrostomy Before Definitive Concurrent Chemoradiation Therapy for Esophageal Squamous Cell Carcinoma No drug interventions treatment 2 completed NCT06508229
Adebrelimab Combined With Albumin Paclitaxel and Nedaplatin as Neoadjuvant Therapy for Locally Advanced Resectable ESCC treatment 2 not_yet_recruiting NCT04510129
A Multicenter Cancer Biospecimen Collection Study No drug interventions Not Available Not Available recruiting NCT01551589
Involved Field Irradiation (IFI) Versus Elective Nodal Irradiation (ENI) for Esophageal Cancer treatment Not Available completed NCT01258192
Neoadjuvant Chemotherapy With Nab-paclitaxel Plus Cisplatin for Stage Ⅱ-Ⅲ Esophageal Cancer Patients treatment 2 completed NCT06468644
Phase II Study of Different Doses of Radiotherapy Combined With Sintilimab in the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT04548440
Efficacy and Safety of Preoperative Sintilimab Plus Nab-paclitaxel and Cisplatin in BR-ESCC Patients treatment 2 completed NCT03817567
Safety and Efficacy of SCT200 in Patients With Advanced Esophageal Squamous Cell Carcinoma No drug interventions treatment 1 / 2 unknown_status NCT04503967
Efficacy and Safety of Anlotinib Hydrochloride Combined With Nivolumab in the Treatment of Gastric and Esophageal Cancer treatment 2 unknown_status NCT03940001
A Study of Sintilimab Plus Chemoradiation Before Surgery for Esophageal Cancer treatment 0 unknown_status NCT05348668
Hybrid Dose-fraction Radiotherapy for Metastatic Non-small Cell Lung Cancer No drug interventions treatment 2 recruiting NCT05626569
Anti-PD-1 Immunotherapy Combined With SBRT for Patients With Oligometastatic ESCC No drug interventions treatment 2 recruiting NCT03946969
Sintilimab in Combination With Chemotherapy in Neoadjuvant Treatment of Potentially Resectable Esophageal Cancer treatment 2 unknown_status NCT03985046
Sintilimab Plus Chemotherapy Followed by dCRT in Locally Advanced ESCC treatment 2 completed NCT05213312
Study of Neoadjuvant Nivolumab or Placebo Plus Chemotherapy Followed by Surgery and Adjuvant Treatment in Subjects With Resectable ESCC treatment 2 / 3 unknown_status NCT04138212
Neoadjuvant Chemotherapy Versus Neoadjuvant Chemoradiotherapy for Resectable Locally Advanced Esophageal Cancer (HCHTOG1903) treatment 3 recruiting NCT06192212
PPIO-005 The Relationship Between Different Nutritional Pathways and Tumor Outcomes After Minimally Invasive Esophagectomy No drug interventions Not Available Not Available active_not_recruiting NCT04866381
An Exploratory Clinical Study of SHR6390 and SHR1020 in the Treatment of Esophageal Squamous Cell Carcinoma After Progression on PD-1 Antibody treatment 2 unknown_status NCT06084481
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400 No drug interventions treatment 1 recruiting NCT04767295
A Study of Camrelizumab Combined With Chemotherapy as Neoadjuvant Therapy in Adcanced Esophageal Squamous Cell Carcinoma (ESCC) treatment 2 unknown_status NCT02658214
Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors treatment 1 completed NCT05557955
Identification of Breath Biomarkers in Esophageal Cancer No drug interventions Not Available Not Available completed NCT04584008
Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics No drug interventions treatment Not Available recruiting NCT06420908
Adebrelimab Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) treatment Not Available not_yet_recruiting NCT06010303
A Study to Evaluate LBL-007 in Combination With Tislelizumab Plus Chemotherapy in Participants With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma treatment 2 active_not_recruiting NCT05281003
Pembrolizumab Plus Chemo in Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma (Eastern Cooperative Thoracic Oncology Projects 2004, ECTOP-2004) treatment 2 recruiting NCT05596890
Patient-reported Outcomes in Preoperative Immunochemotherapy/Radiotherapy-treated Esophageal Cancer Patients treatment 2 recruiting NCT04225364
Efficacy of Neoadjuvant PD-1 Blockade Plus Chemotherapy for Esophageal Squamous Cell Carcinoma treatment 2 completed NCT03224221
Apatinib Combined With Chemotherapy for Esophageal Squamous Cell Cancer After the Failure of Standard Treatment treatment 2 unknown_status NCT02665702
Endostar Combined With NVB and DDP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas treatment 2 unknown_status NCT02435602
The Role of Chromoendoscopy in the Early Detection of Esophageal Cancer in Patients With Prior Head and Neck Cancers No drug interventions screening Not Available completed NCT06487702
A Phase lb/lI Clinical Study in Advanced or Metastatic Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT06408584
Short-course Hypofractionated Radiotherapy in Combination With Raltitrexed and Tislelizumab No drug interventions Not Available Not Available recruiting NCT02890979
Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease No drug interventions device_feasibility Not Available completed NCT06047379
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis treatment 1 / 2 recruiting NCT04522687
Influence of Radiotherapy and Chemotherapy in the Value of Peripheral Blood Lymphocyte Subsets Among Thoracic Cancer No drug interventions Not Available Not Available recruiting NCT05896787
Candonilimab (AK104) Plus Preoperative Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma (ESCC) treatment 2 not_yet_recruiting NCT03790553
Comparing 61.2 Gy Radiotherapy Dose Versus 50.4 Gy Radiotherapy Dose for Locally Advanced Esophageal Carcinoma No drug interventions treatment 3 recruiting NCT02586753
Paclitaxel or S1 Plus Cisplatin in Concurrent Chemoradiotherapy for Squamous Cell Carcinoma of Esophagus No drug interventions treatment 2 unknown_status NCT04389177
Pembrolizumab Plus Paclitaxel, Cisplatin Followed by Surgery for Locally Advanced ESCC (KEYSTONE-001) treatment 2 active_not_recruiting NCT06410677
Changhai Multimodal Esophageal Cancer Cohort No drug interventions Not Available Not Available active_not_recruiting NCT03273647
Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma With Positive Circumstantial Resection Margin No drug interventions treatment 3 not_yet_recruiting NCT05007145
PD-1 Inhibitor Combined With Neoadjuvant Chemotherapy in Subjects With Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT05541445
Pembrolizumab Plus CRT Followed by Surgery in Upper ESCC treatment 1 / 2 recruiting NCT04212598
The Value of Sintilimab Consolidation Therapy After Definitive Concurrent Chemoradiotherapy for Locally Advanced Thoracic Esophageal Cancer treatment 2 recruiting NCT05144698
RAPA-201 Therapy of Solid Tumors treatment 1 / 2 recruiting NCT05244798
Sintilimab Plus NCT or NCRT Versus NCRT for ESCC treatment 3 not_yet_recruiting NCT01605305
Study on FOLFOX6 as First-line Therapy to Treat Recurrent or Metastatic Esophageal Cancer No drug interventions treatment 2 completed NCT02677597
Cisplatin Combined With S-1 or Paclitaxel as First-line Treatment for Metastatic Esophageal Squamous Cell Carcinoma treatment 3 unknown_status NCT05900583
Efficacy Evaluation and Recurrence Monitoring of Therapy for Esophageal Squamous Cell Carcinoma Based on ctDNA-MRD. No drug interventions Not Available Not Available not_yet_recruiting NCT04063683
Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma（ESCC）. treatment 2 unknown_status NCT02649361
Study of Anlotinib in Patients With Esophageal Squamous Cell Carcinoma (ALTER1102) treatment 2 completed NCT05469061
Tislelizumab in Combination With Chemotherapy for Conversion Therapy of Locally Nonresectable ESCC treatment 2 unknown_status NCT05044728
Exploration of Immunodynamic Monitoring in the Population Evaluation of Neoadjuvant Chemotherapy Immunotherapy in Patients With Solid Tumors of the Chest. treatment 2 unknown_status NCT05507411
Watch and Wait for NeoAdjuvant Concurrent Radiochemotherapy Combined With Camrelizumab in Patients With Resectable ESCC No drug interventions treatment 2 recruiting NCT06178211
Neoadjuvant Adebrelimab Plus Chemotherapy for Resectable ESCC: a Single Arm, Prospective Phase 2 Clinical Trial treatment 2 not_yet_recruiting NCT05302011
Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma treatment 2 completed NCT02384811
Phase II Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy for Esophageal Squamous Cell Carcinoma No drug interventions treatment 2 unknown_status NCT02916511
Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy Concurrent With Chemotherapy for Esophageal Squamous Cell Carcinoma treatment 2 completed NCT06152978
A Perioperative Sintilimab and Chemotherapy in Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT05252078
Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients treatment 2 recruiting NCT03766178
Study of Anti-PD-1 Antibody SHR-1210 Plus Nimotuzumab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT03185988
Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System treatment 2 unknown_status NCT03592407
Epacadostat and Pembrolizumab Before Surgery in Treating Participants With Stage II-III Esophageal or Gastroesophageal Cancer treatment 2 withdrawn NCT02976909
Efficacy and Safety of TPF Induction Chemotherapy for Borderline-resectable Esophageal Squamous Cell Carcinoma treatment 2 completed NCT05386056
Pembrolizumab and Photodynamic Therapy in Previously Treated Metastatic Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT05170256
Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma Patients treatment 2 recruiting NCT06020885
Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study. No drug interventions treatment 1 recruiting NCT04229537
Study of SCT-I10A Combined SCT200 or SCT-I10A Combined SCT200 Plus Chemotherapy in ESCC and CRC treatment 1 unknown_status NCT03623737
Comparing Paclitaxel/Cisplatin and Cisplatin/5-fluorouracil in Neo-CRT for ESCC No drug interventions treatment 2 / 3 unknown_status NCT02915432
The Study to Evaluate Toripalimab (JS001) in Patients With Advanced GC, ESCC, NPC, HNSCC treatment 1 / 2 unknown_status NCT04199832
To Compare the Effect of Different Nutritional Pathways on Improving Nutritional Status of Esophageal Cancer Patients Undergoing Chemoradiotherapy No drug interventions Not Available Not Available completed NCT04851132
Radiotherapy Plus Durvalumab in Elderly Esophageal Squamous Cell Carcinoma treatment Not Available unknown_status NCT04440332
Surveillance of Peripheral Blood of Lymphocyte and Immunocyte in Neoadjuvant Therapy Patients With Esophageal Squamous Cell Carcinoma (pLINE) No drug interventions Not Available Not Available unknown_status NCT04389632
A Study of SGN-B6A in Advanced Solid Tumors treatment 1 recruiting NCT04460352
Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer treatment 3 recruiting NCT04140500
Dose Escalation Study of a PD1-LAG3 Bispecific Antibody in Patients With Advanced and/or Metastatic Solid Tumors treatment 1 / 2 recruiting NCT04229459
Trial of Nivolumab and Cetuximab After Chemoradiation in Esophageal Squamous Cell Carcinoma Patients. treatment 2 recruiting NCT03925870
KN046 in Subjects With Late Stage Esophageal Squamous Cell Carcinoma treatment 2 completed NCT04242199
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors No drug interventions treatment 1 active_not_recruiting NCT02272699
Neoadjuvant Treatment of Nimotuzumab With Chemotherapy or Radiotherapy in Resectable Esophageal Squamous Cell Carcinoma treatment 2 / 3 withdrawn NCT04813406
Study of Anlotinib Plus Sintilimab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma treatment Not Available unknown_status NCT01398449
Is ENI Necessary For Patients With Thoracic Esophageal Cancer After Esophagectomy And With Pathological Stage Of T1-2,N+,M0 No drug interventions treatment 3 unknown_status NCT03713749
Robotic-assisted Esophagectomy vs. Video-Assisted Thoracoscopic Esophagectomy(REVATE) Trial No drug interventions treatment Not Available unknown_status NCT06056336
Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma treatment 2 recruiting NCT05392413
Immune Indicator Model for Predicting Efficacy of PD-1 Monoclonal Antibody No drug interventions Not Available Not Available recruiting NCT05038813
Anlotinib Combined With TQB2450 (PD-L1 Inhibitor) in the Treatment of Advanced Esophageal Squamous Cell Carcinoma(ESCC) treatment 2 active_not_recruiting NCT04115618
SIB in Upper Thoracic Esophageal Squamous Cell Carcinoma No drug interventions treatment 2 unknown_status NCT04984018
Chidamide Plus Camrelizumab as Second-line Therapy for Advanced ESCC Treated With PD-1 Blockade treatment 2 unknown_status NCT05490719
A Phase II Study of CRT Combined With QL1706 in ESCC Patients treatment 2 recruiting NCT02023541
Proton Beam Therapy to Treat Esophageal Cancer No drug interventions treatment 1 terminated NCT06063941
High-concentration Small-volume Versus Low-concentration Large-volume Iodine Solution for Esophageal Chromoendoscopy supportive_care Not Available completed NCT02350517
Endostar Combined With Paclitaxel and Nedaplatin in Treating Patients With Recurrent or Metastatic Esophageal Cancer treatment 2 completed NCT06194734
A Study of KC1036 Versus Investigator's Choice of Chemotherapy in Patients With Advanced Esophageal Cancer treatment 3 recruiting NCT04272034
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors No drug interventions treatment 1 active_not_recruiting NCT06463834
A Study of Sintilimab Combined With Chemotherapy for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma treatment 2 recruiting NCT04229524
Quantitative Assessment of Blood Supply in the Gastic Conduit With Fluorescence Angiography for Esophageal Reconstruction No drug interventions prevention Not Available unknown_status NCT05650216
Camrelizumab Combined With Neoadjuvant Concurrent Chemoradiotherapy for Resectable Locally Advanced ESCC（NICE-RT） treatment 2 not_yet_recruiting NCT02606916
Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Cancer. No drug interventions treatment 2 completed NCT04045496
A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors No drug interventions treatment 1 unknown_status NCT04084158
A Study of Toripalimab Combined With Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma. treatment 2 suspended NCT04514835
A Phase Ⅱ Trials of Sintilimab as Consolidation Therapy After Radical Concurrent Chemoradiotherapy in Locally Advanced Unresectable ESCC treatment 2 unknown_status NCT01591135
A Phase III Study of Comparing Paclitaxel Plus 5-Fluorouracil Versus Cisplatin Plus 5-Fluorouracil in Chemoradiotherapy for Locally Advanced Esophageal Carcinoma treatment 3 completed NCT04759235
Multimodal Functional Imaging Combined With Metabolomics in Predicting the Efficacy of nCRT for Locally Advanced ESCC No drug interventions Not Available Not Available unknown_status NCT04224363
Whether it is More Appropriate to Spray Lugol's Solution From Cervical Esophagus to Esophagogastric Junction No drug interventions diagnostic Not Available unknown_status NCT04121286
A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China No drug interventions treatment 1 recruiting NCT06281886
Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma treatment 2 recruiting NCT06190639
A Clinical Study of Sintilimab as Adjuvant Therapy in Node-positive ESCC treatment 2 recruiting NCT01608022
A Phase II Trial of PF-00299804 in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of Esophagus No drug interventions treatment 2 completed NCT04514822
Quantitative Evaluation of Metastatic Lymph Nodes With Dynamic 18F-FDG PET/CT in Patients With ESCC No drug interventions diagnostic Not Available unknown_status NCT05174325
Effectiveness of Neoadjuvant Chemotherapy Combined With PD-1 Monoclonal Antibody in the Treatment of Operable Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT05028725
Novel Strategy for Early Detection of Esophageal Squamous Cell Carcinoma No drug interventions diagnostic Not Available recruiting NCT01973725
Study of Icotinib Hydrochloride in Treating Patients With Recurrent or Metastatic Esophageal Cancer After Failure of Conventional Chemotherapy treatment 2 completed NCT03797625
Endostar Combined With IP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas treatment 2 unknown_status NCT05189730
Selected Chemotherapy Combined Immunotherapy Treated High Risk Patient After NCRT in Resected Locally Advanced ESCC treatment 2 unknown_status NCT03922230
Exploration and Verification of DNA Methylolation in Early Screening of Esophageal Cancer No drug interventions Not Available Not Available unknown_status NCT06354530
A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma treatment 2 / 3 recruiting NCT04170257
Performance of White Light, NBI and Iodine Staining Endoscopy in the Diagnosis of Esophageal Lesions No drug interventions screening Not Available unknown_status NCT06048926
Carrelizumab Combined With Concurrent Radiotherapy and Chemotherapy for Unresectable Esophageal Squamous Cell Carcinoma treatment Not Available enrolling_by_invitation NCT03278626
Immune Checkpoint Therapy With Nivolumab Esophageal Squamous Cell Carcinoma treatment 1 / 2 terminated NCT06241066
The Prognostic Value of Tertiary Lymphatic Structure in Esophageal Squamous Cell Carcinoma No drug interventions Not Available Not Available completed NCT05563766
A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer treatment 2 not_yet_recruiting NCT03833466
Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) treatment 2 unknown_status NCT02913066
S-1 IMRT Versus S-1 and Cisplatin Concurrent IMRT in Inoperable Esophageal Squamous Cell Carcinoma No drug interventions treatment 2 unknown_status NCT06304974
A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma treatment 3 recruiting NCT05880082
PPIO-004 Clinical Application of Efficacy Prediction Model Based on Epigenomics Sequencing Technology in Neoadjuvant Immunotherapy for Esophageal Cancer treatment 2 enrolling_by_invitation NCT05990231
Cadonilimab/Anlotinib in Locally Advanced or Relapsed/Metastatic ESCC Patients After Failure of PD-1 Combined With Platinum-containing Chemotherapy treatment 2 recruiting NCT03600831
Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Patients With Locoregionally Advanced Esophageal Squamous Cell Carcinoma treatment 2 / 3 completed NCT05462873
A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT00901173
A Pilot for a Case-Control Study of Esophageal Squamous Cell Carcinoma in Western Kenya No drug interventions Not Available Not Available completed NCT06576973
Adbelimumab Combined With Chemotherapy and Apatinib in Patients With Resectable Esophageal Squamous Cell Carcinoma treatment 2 recruiting NCT03940976
Afatinib in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification (ESCC-A01) treatment 2 unknown_status NCT04732494
AdvanTIG-203: Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma treatment 2 completed NCT06165380
Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma No drug interventions treatment 2 recruiting NCT05420480
Two-field Versus Three-field Lymph Node Dissection in ESCC After Neoadjuvant Therapy No drug interventions treatment Not Available not_yet_recruiting NCT05287880
Quantitative Analysis of 18F-FAPI Dynamic PET/CT for Accurate Differential Diagnosis of MLN of ESCC No drug interventions Not Available Not Available unknown_status NCT02100189
Esophageal Cytology With FISH in Detecting Esophageal Cancer No drug interventions screening Not Available completed NCT04929392
Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer treatment 2 active_not_recruiting NCT03888092
Z650 in Advanced Esophageal Squamous Cell Carcinoma With EGFR Over Expression or Gene Amplification No drug interventions treatment 1 / 2 completed NCT05927844
XH-30002 Capsule Combined With Afatinib Tablets for the Treatment of Squamous Cell Carcinoma No drug interventions treatment 1 not_yet_recruiting NCT04764240
Precisely Estimation of the Prognostic Value of Lymph Node in ESCC No drug interventions Not Available Not Available completed NCT06354140
PPIO-008 Tislelizumab Combined With S-1 in Patients With ypT+N0 ESCC After Radical Resection With Neoadjuvant STUDY treatment 2 recruiting NCT03322267
Adjuvant Pembrolizumab for Patients With Locally Advanced Esophageal Squamous Cell Carcinoma at High Risk of Recurrence treatment 2 active_not_recruiting NCT03387904
Study of Anlotinib Plus Irinotecan in Patients With Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT04032704
A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors treatment 2 terminated NCT01391572
A Trial Estimating The Optimal Radiation Volume Of Postsurgical Radiation For Patients With Esophageal Cancer treatment 2 unknown_status NCT05312372
S095033 in Combination With Paclitaxel as 2nd- or 3rd-line Treatment in Participants With Advanced or Metastatic ESCC treatment 1 / 2 withdrawn NCT06509568
Neoadjuvant ChemoRadiotherapy Followed by Immunotherapy and Surgery for Resectable Esophageal Squamous Cell Carcinoma（CRIS-2 Trial） No drug interventions treatment 2 recruiting NCT06563869
Sintilimab With Chemotherapy Plus PEG-rhG-GSF for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma No drug interventions treatment 3 recruiting NCT06329869
Sacituzumab Govitecan for Advanced Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT01807546
Oral Rigosertib for Squamous Cell Carcinoma treatment 2 completed NCT06010212
Fruquintinib as First Line Treatment in Patients With Recurrent Esophageal Squamous Cell Carcinoma treatment 1 / 2 not_yet_recruiting NCT03927495
KN046 in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT05740995
Neoadjuvant Anti-PD-1 Plus Chemotherapy in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma No drug interventions Not Available Not Available recruiting NCT03187314
Combination of Radiation Therapy and Anti-PD-1 Antibody SHR-1210 in Treating Patients With Esophageal Cancer treatment 2 completed NCT05594914
AK104 Plus Concurrent Chemoradiation Therapy in Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT02964455
Study of Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma treatment 1 completed NCT06006650
Neoadjuvant Therapy for Stage II-IVA Resectable Esophageal Squamous Cell treatment 2 recruiting NCT05426850
ctDNA-based MRD Assessment in Local Advanced Esophageal Carcinoma No drug interventions Not Available Not Available recruiting NCT05604950
Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 Years No drug interventions Not Available Not Available completed NCT04644250
Combination of Toripalimab and Neoadjuvant Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma treatment 2 unknown_status NCT05636150
A Phase II Clinical Study of Fruquintinib Combined With S-1 for Advanced Esophageal Squamous Cell Carcinoma treatment 2 recruiting NCT01688908
Efficacy of Endoscopy Screening on Esophageal Cancer in China (ESECC) No drug interventions screening Not Available active_not_recruiting NCT04506138
Camrelizumab in Combination With Neoadjuvant Chemotherapy for Resectable Thoracic Esophageal Squamous Cell Carcinoma treatment 1 / 2 active_not_recruiting NCT04545827
Study to Evaluate the Safety of IMM-01 in Patients With Advanced Solid Tumours basic_science 1 not_yet_recruiting NCT03585673
Docetaxel-polymeric Micelles(PM) and Oxaliplatin for Esophageal Carcinoma treatment 2 unknown_status NCT05865132
Palbociclib Combined With Afatinib for Advanced Squamous Carcinoma of Esophagus or Gastroesophageal Junction treatment 2 recruiting NCT03585530
Raltitrexed Concurrent With Radiotherapy for Elderly Chinese Patients With Squamous Cell Carcinoma of Esophagus treatment 2 unknown_status NCT03712566
Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy No drug interventions Not Available Not Available active_not_recruiting NCT04018872
Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer treatment 2 recruiting NCT04713891
A Study of KF-0210 in Advanced Solid Tumors Patients treatment 1 completed NCT03762564
Study With Paclitaxel +/- Ramucirumab in Patients With Squamous-cell Carcinoma of the Esophagus After Prior Therapy treatment 2 completed NCT00064259
A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer treatment 1 / 2 terminated NCT01129206
Pralatrexate and Docetaxel in Treating Patients With Stage IV Esophageal or Gastroesophageal Cancer Who Have Failed Platinum-Based Therapy treatment 2 completed NCT01212822
Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer treatment 2 completed NCT01561014
Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction treatment 1 completed NCT03307941
Assessment of Metabolic & Path Response w/ RCT & ImT Before Surgery in Locally Advanced Esoph and Gastro-esoph Jction CA treatment 1 / 2 withdrawn NCT00045526
Erlotinib Hydrochloride in Treating Patients With Advanced Esophageal Cancer or Stomach Cancer treatment 2 completed NCT01612546
Pilot Trial of CRLX101 in Treatment of Patients With Advanced or Metastatic Stomach, Gastroesophageal, or Esophageal Cancer That Cannot be Removed by Surgery treatment 2 completed NCT06055153
DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC treatment 1 / 2 not_yet_recruiting NCT01752205
Paclitaxel Plus Radiation With Erlotinib to Treat Esophageal Squamous Carcinoma treatment 3 unknown_status NCT05164848
JMT101 Combined With Afatinib in Patients With Advanced Esophageal Squamous Cell Carcinoma After Standard Therapy treatment 1 unknown_status NCT06603402
Low-Dose Involved-Field Radiotherapy Plus Immunochemotherapy for ESCC No drug interventions treatment 2 recruiting NCT04839471
BI-754091 and Afatinib for Refractory Esophageal Squamous Cell Carcinoma (BEAR Study) treatment 2 completed NCT06504615
Observational Study of Patients Treated With Nivolumab and Chemotherapy for Advanced or Metastatic Esophageal, Gastroesophageal or Gastric Cancer in France Not Available Not Available not_yet_recruiting NCT03783442
A Study of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma treatment 3 active_not_recruiting NCT05342636
A Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A) treatment 1 / 2 active_not_recruiting NCT03957590
Study of Tislelizumab (BGB-A317) Versus Placebo in Combination With Chemoradiotherapy in Participant With ESCC treatment 3 active_not_recruiting NCT03708328
A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors treatment 1 completed NCT05473156
A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies No drug interventions treatment 1 / 2 not_yet_recruiting NCT04210115
Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975) treatment 3 active_not_recruiting NCT06078657
IBI110 Combined With Sintilimab in Second-line Advanced or Metastatic Esophageal Squamous Cell Carcinoma(ESCC) treatment 2 not_yet_recruiting NCT03430843
A Study of Tislelizumab (BGB-A317) Versus Chemotherapy as Second Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma treatment 3 completed NCT02353936
A Phase II Trial of Afatinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of Esophagus treatment 2 unknown_status NCT02041819
Neoadjuvant Chemotherapy of Nimotuzumab Plus Nab-Paclitaxel in Squamous Cell Carcinoma of Esophagus treatment 2 withdrawn NCT00165490
Combination Chemotherapy, Radiation Therapy and Surgery for Esophageal Cancer treatment 2 completed NCT04196075
The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer No drug interventions supportive_care 3 completed NCT01248299
Benefit of Chemotherapy Over Best Supportive Care in Metastatic and Squamous Cell-type Esophageal Cancer. treatment 2 terminated NCT05759325
An Exploratory Study of ctDNA-MRD in Predicting the Efficacy of Esophageal Squamous Cell Carcinoma No drug interventions Not Available Not Available not_yet_recruiting NCT02033538
Neoadjuvant Chemotherapy of Nanoparticle Albumin-bound Paclitaxel in Squamous Cell Carcinoma of Esophagus treatment 2 withdrawn NCT04802876
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors treatment 2 recruiting NCT02188615
Study of Neo-adjuvant Chemoradiotherapy Followed by Minimally Invasive Esophagectomy for Squamous Cell Esophageal Cancer treatment 2 unknown_status NCT05357846
PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101) treatment 3 recruiting NCT01216527
Phase III Study of Neo-adjuvant Chemoradiotherapy Followed by Surgery for Squamous Cell Esophageal Cancer No drug interventions treatment 3 unknown_status NCT06489197
AK112 Combined With Chemotherapy as the First-line Treatment in Advanced Esophageal Squamous Cell Carcinoma Patients treatment 2 not_yet_recruiting NCT06478355
Immunotherapy Combined With Chemoradiotherapy for First-line Treatment of Esophageal Squamous Cell Carcinoma（ChinECR） No drug interventions treatment Not Available active_not_recruiting NCT04863079
Pembrolizumab in Post Radical Operation ESCC Patients With Lymph Node Positive ( KEYSTONE-004 ) treatment 2 unknown_status NCT05547828
Efficacy and Safety of Tislelizumab and Nab-paclitaxel Combined With Low-dose Radiotherapy in Patients With Stage IVb Esophageal Squamous Cell Carcinoma treatment 2 not_yet_recruiting NCT04686682
A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors No drug interventions treatment 1 / 2 recruiting NCT05050760
DCF Combined With Camrelizumab in the Treatment of Esophageal Cancer health_services_research Not Available unknown_status NCT06531291
Surufatinib Combined With Serplulimab and Standard Chemotherapy as First-line Treatment in Advanced Solid Tumors With Neuroendocrine Differentiation treatment 2 not_yet_recruiting NCT04471480
TC Plus PD-1 Inhibitors Combined With Anlotinib for Advanced Advanced Esophageal Cancer treatment Not Available unknown_status NCT04939701
Study of ASP0739 Alone and With Pembrolizumab in Advanced Solid Tumors With NY-ESO-1 Expression Participants No drug interventions treatment 1 / 2 terminated NCT04741490
Camrelizumab Combined With Radiotherapy for Adjuvant Treatment of Esophageal Squamous Cell Carcinoma After Surgery treatment Not Available unknown_status NCT05621707
Chemoradiotherapy Following Immunotherapy Plus Chemotherapy for Locally-advanced Esophageal Squamous Cell Cancer (RICE) No drug interventions treatment 2 not_yet_recruiting NCT02611700
Nimotuzumab in Combined With Paclitaxel and Cisplatin for Treatment of Metastatic Esophageal Squamous Cell Carcinoma treatment 3 unknown_status NCT05103501
Salvage Immunotherapy and Chemotherapy in Esophageal Squamous Cell Carcinoma Patients Nonresponding to Initial Neoadjuvant Chemoradiotherapy treatment 2 not_yet_recruiting NCT05022654
SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma. treatment 2 recruiting NCT05104567
A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203) treatment 2 active_not_recruiting NCT04215471
NeoAdjuvant Therapy With Immunoreagent (SHR-1316) for Resectable Oesophageal Squamous Cell carciNoma treatment 2 unknown_status NCT06169163
Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms No drug interventions Not Available Not Available recruiting NCT04925284
Study of XB002 in Subjects With Solid Tumors (JEWEL-101) treatment 1 active_not_recruiting NCT04000529
Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies treatment 1 terminated