Ulcers, Leg (DBCOND0125075)

Identifiers

Synonyms
Ulcer, Leg / Leg Ulcers / Leg Ulcer / Leg ulcer (disorder) / Lower extremities ulcers of / Non-pressure chronic ulcer of skin, not elsewhere classified / Skin ulcer NOS / Skin ulceration / Skin ulcer / Skin ulcer (disorder) / Ulcer skin

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Chlorhexidine
An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.
Lidocaine
A local anesthetic used in a wide variety of superficial and invasive procedures.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03126396
Assessment of Efficacy & Tolerance of Urgo 310 3166 Dressing in Local Venous or Mixed Leg UlcersNo drug interventionstreatmentNot Availablecompleted
NCT05890703
Painless Sharp Wound Debridement With Lidocaine-23%-Tetra-caine-7% Gel Versus EMLA 5% Creamtreatment2recruiting
NCT04123093
Safety and Efficacy of the Noxsano Wound Care BandageNo drug interventionsotherNot Availableterminated
NCT05234632
Study to Evaluate the PICO 14 Negative Pressure Wound Therapy System in the Management of Acute and Chronic WoundsNo drug interventionstreatmentNot Availableterminated
NCT03468816
Wound Dressing With Moisture SensorNo drug interventionstreatmentNot Availablecompleted
NCT05285930
Effect of Bee Venom Phonophoresis on Healing of Chronic Lower Limb UlcerstreatmentNot Availablecompleted
NCT05564728
Diabetes Footcare Companion App for Patients and CarersNo drug interventionsNot AvailableNot Availablecompleted
NCT02904707
Interest of Skin Graft Pellets in the Management of Ulcers AlgicNo drug interventionsNot AvailableNot Availablecompleted
NCT04210089
Total Contact Soft Cast in Diabetic Foot UlcersNo drug interventionstreatmentNot Availablerecruiting
NCT04890769
Clinical Study of Moisture Sensor Dressing Used for Exuding WoundsNo drug interventionsNot AvailableNot Availableterminated
NCT05561140
Resolution of Sickle Cell Leg Ulcers With Voxelotortreatment3active_not_recruiting
NCT00807664
Biatain Ag vs Biatain in the Treament of Leg UlcersNo drug interventionstreatmentNot Availablecompleted
NCT00522002
CLUE Study: Connective Tissue Disease Leg Ulcer Etiology StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00007280
Bioengineered Skin and Wound HealingNo drug interventionstreatment1completed
NCT00922389
A Clinical Trial on Diabetic Foot Using Peripheral Blood Derived Stem Cells for Treating Critical Limb Ischemiatreatment1 / 2unknown_status
NCT00762138
The AutoloGel™ Post-Market Surveillance (TAPS) ProgramNo drug interventionsNot AvailableNot Availableterminated
NCT01238419
Physiotulle vs Urgotul in the Treatment of Leg UlcerNo drug interventionstreatment4completed
NCT02583958
Assessment of Efficacy & Safety for a New Wound Dressing Urgo 310 3166 in the Local Treatment of VLU or Mixed Leg UlcersNo drug interventionstreatmentNot Availableunknown_status
NCT00821431
Compression Device Versus 4-layer Compression SystemNo drug interventionstreatment2completed
NCT00184873
Legtest Multi Centre Testing of the Lively Legs Program for Promoting Compliance in Leg Ulcer PatientsNo drug interventionspreventionNot Availablecompleted
NCT00627094
Biatain Ibu vs. Biatain in Painful Chronic Venous Leg UlcersNo drug interventionstreatmentNot Availablecompleted
NCT01427491
Compare Aquacel® Ag Versus Mepilex® Border Ag to Manage Bioburden in Leg UlcersNo drug interventionstreatment3completed
NCT00710489
Potential Research Study Participant RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT00628004
Safety Evaluation of Biatain Ibu in Painful Chronic Venous Leg UlcersNo drug interventionstreatmentNot Availablecompleted
NCT02632695
Physical Activity Interventions for Leg Ulcer PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT06326203
Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb IschemiaNo drug interventionstreatment1 / 2not_yet_recruiting
NCT02600390
SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcertreatment2completed
NCT02280733
A Real World, Observational Registry of Chronic Wounds and UlcersNo drug interventionsNot AvailableNot Availablerecruiting
NCT01084577
AQUACEL® Ag Dressing and Urgotul® Silver Dressing on Healing of Chronic Venous Leg UlcersNo drug interventionstreatment4completed
NCT03086577
Pain in Chronic Leg- and Foot UlcersNo drug interventionsNot AvailableNot Availableunknown_status
NCT04980898
Electrostimulation System WoundEL for Leg Ulcers Healing (No drug interventionstreatmentNot Availablerecruiting
NCT05303805
Topical Sevoflurane for Treatment of Chronic Leg Ulcerstreatment4recruiting
NCT02873728
Remote Ischemic Conditioning for Treatment of Chronic WoundsNo drug interventionstreatmentNot Availableunknown_status
NCT05057793
Efficacy Study for Geko Device in VLU Patients (Canada)No drug interventionstreatmentNot Availableterminated
NCT02973893
Study of VF001-DP in Patients With Chronic Venous Leg UlcersNo drug interventionstreatment2unknown_status
NCT00371371
Intra-arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI)No drug interventionstreatment1 / 2completed
NCT00235209
A Study to Evaluate the Clinical Effectiveness of a Collagen-ORC Antimicrobial Matrix in Venous Leg UlcersNo drug interventionsdiagnostic4completed
NCT02993809
Autologous Transplantation of BM-ECs With Platelet-Rich Plasma Extract for the Treatment of Critical Limb IschemiaNo drug interventionstreatment1unknown_status
NCT01770509
The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot StudyNo drug interventionstreatment1 / 2completed
NCT02626156
Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer RecurrenceNo drug interventionstreatment2completed
NCT06036485
Efficacy of Kerecis Omega 3 in Comparison to Clinical Standard ProceduresNo drug interventionstreatmentNot Availablewithdrawn
NCT05619237
Pivotal Study of an Antimicrobial Wound Dressing to Treat Chronic WoundsNo drug interventionstreatmentNot Availablecompleted
NCT00838500
THERMES ET VEINES: Spa for Prevention of Leg UlcersNo drug interventionstreatment3completed
NCT03644849
Evaluating the Safety and Efficacy of Fractionated Carbon Dioxide Therapy in Postoperative Lower Extremity Wound HealingNo drug interventionstreatmentNot Availablecompleted
NCT02889913
When Asking the Indication of a Skin Biopsy From a Patient With a Leg Ulcer in Primary Care?No drug interventionsNot AvailableNot Availablecompleted
NCT01657318
Olivamine-containing Products in the Management of Patients With Nonhealing Lower Extremity UlcersNo drug interventionsNot AvailableNot Availableterminated
NCT01591434
Study to Evaluate the Performance of AQUACEL® Extra™ in Venous Leg UlcersNo drug interventionstreatment3completed
NCT00434616
Autologous Bone Marrow Stem Cell Transplantation for Critical, Limb-threatening IschemiaNo drug interventionstreatment2 / 3unknown_status
NCT02889926
Utility of Samples in Bacteriological Prospective Series of Ulcers Leg Infected ClinicallyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03396731
Efficacy Study for Geko Device in VLU PatientsNo drug interventionstreatmentNot Availablecompleted
NCT00232973
Safety and Efficacy Study of ICXP007 With Compression Bandaging for the Treatment of Non-Infected Venous Leg UlcersNo drug interventionstreatment3unknown_status
NCT01966380
Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, LeiaNo drug interventionstreatment2terminated
NCT00759889
Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06153589
Effectiveness of Musicotherapy in Reducing Pain Induced by Leg Ulcer CareNo drug interventionsotherNot Availablenot_yet_recruiting
NCT01903044
Safety and Efficacy of Autologous Bone Marrow Stem Cells for Lower Extremity Ischemia TreatingNo drug interventionstreatment1 / 2unknown_status
NCT01551667
Immune Response of Patients With Chronic, Staphylococcus Aureus-infected WoundsNo drug interventionsNot AvailableNot Availablecompleted
NCT01673412
Research of Prognostic Factors Associated With Healing of Venous Leg UlcersNo drug interventionsNot AvailableNot Availablecompleted
NCT01111695
Evaluation of a Ionic Silver and Honey Preparation to Treat Chronic Wounds of the Lower LegsNo drug interventionstreatment2completed
NCT05274295
Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Diabetic Leg UlcersNo drug interventionsdevice_feasibilityNot Availableunknown_status
NCT00399308
Evaluation of Safety and Activity of Celaderm in Healing Venous Leg UlcersNo drug interventionstreatment1 / 2completed
NCT06007703
Evaluation of the Efficacy of Multilayer Compression & UrgoStart PlusNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02011503
Use of dHACM in the Treatment of Venous Leg UlcersNo drug interventionstreatmentNot Availablecompleted
NCT05148390
Study to Examine Clinical Performance and Safety of Cutimed® Gelling Fiber in Routine Clinical PracticeNo drug interventionsNot AvailableNot Availablecompleted
NCT02392390
Effects of Topical Dynamic Phototherapy on the Microbiota of Chronic WoundstreatmentNot Availablecompleted
NCT02842502
Clinical Feasibility of an Advanced Therapy Medicinal Product (ATMP) Preparation for Autologous Skin Regeneration in Case of Chronic Leg UlcersNo drug interventionsbasic_scienceNot Availableunknown_status
NCT06560502
Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02509533
Comparison of the Use of VAC System in Transplants of Leg Ulcers Versus Usual Dressing MethodNo drug interventionstreatmentNot Availableterminated
NCT03146845
Evaluation Of An Advanced Borderless DressingNo drug interventionssupportive_careNot Availablecompleted
NCT03725111
Haemodynamics Variations of Transcutaneous Oxygen in Patient With Areterio-venous Leg Ulcers Under Venous CompressionNo drug interventionstreatmentNot Availablecompleted
NCT06255288
Time to Heal (Wound, Healing, Dialogue, Nutrition)No drug interventionssupportive_careNot Availablerecruiting
NCT00304837
VEGF Gene Transfer for Critical Limb IschemiaNo drug interventionsNot Available1completed
NCT02988063
Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUstreatment4withdrawn
NCT00243620
A Randomised Controlled Trial Comparing Vacuum Assisted Closure (V.A.C.®) With Modern Wound DressingsNo drug interventionstreatmentNot Availablecompleted
NCT03186560
Speckle Study: In Arterial, Mixed and Diabetic Foot UlcersNo drug interventionsotherNot Availableterminated
NCT02987101
Treatment of Chronic Leg Ulcers With Autologous Stromal Vascular FractionNo drug interventionstreatmentNot Availableunknown_status
NCT00270972
The Evaluation of OrCel for the Treatment of Venous UlcersNo drug interventionstreatmentNot Availableunknown_status
NCT00771368
Reduction of Bacteria in MRSA Positive Ulcerstreatment1 / 2terminated
NCT06084546
Geko™ KM40C Hydrogel Skin Adhesion Trial (XW-3)No drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT01497210
EASH Dressing on Chronic Venous Leg UlcersNo drug interventionstreatment2completed