| Zileuton DB00744 |  | Cytochrome P450 2C9 / Cytochrome P450 1A2 | Hydroxyzileuton |  | Details |
| Zileuton DB00744 | | Cytochrome P450 3A4 | Zileuton sulfoxide |  | Details |
| Zileuton DB00744 | | Prostaglandin G/H synthase 1 | Dehydroxyzyleuton |  | Details |
| Zileuton DB00744 | | UDP-glucuronosyltransferase 1-9 | Zileuton O-glucuronide |  | Details |
| Ziprasidone DB00246 |  | Not Available | Ziprasidone Sulfoxide |  | Details |
| Ziprasidone DB00246 | | Not Available | S-Methyl-dihydro-ziprasidone |  | Details |
| Ziprasidone DB00246 | | Not Available | 6-chloro-5-(2-piperazin-1-yl-ethyl)-1,3-dihydro-indol-2-one |  | Details |
| Ziprasidone DB00246 | | Not Available | dihydro-ziprasidone-sulfone |  | Details |
| Ziprasidone DB00246 | | Not Available | (6-chloro-2-oxo-2,3-dihydro-1H-indol-5-yl)acetic acid |  | Details |
| Ziprasidone DB00246 | | Not Available | 3-(piperazine-1-yl)-1,2-benzisothiazole |  | Details |
| Ziprasidone Sulfoxide DBMET02984 | | Not Available | Ziprasidone Sulfone |  | Details |
| Zolmitriptan DB00315 |  | Cytochrome P450 1A2 | Zolmitriptan N-oxide |  | Details |
| Zolmitriptan DB00315 | | Cytochrome P450 1A2 | N-Desmethylzolmitriptan |  | Details |
| Zolpidem DB00425 |  | Cytochrome P450 2C9 / Cytochrome P450 2C19 / Cytochrome P450 3A4 / Cytochrome P450 1A2 / Cytochrome P450 2D6 | Methoxyzolpidem derivative (M3) |  | Details |
| Zolpidem DB00425 | | Cytochrome P450 3A4 / Cytochrome P450 1A2 / Cytochrome P450 2D6 | Methoxyzolpidem derivative (M4) |  | Details |
| Zolpidem DB00425 | | Cytochrome P450 3A4 | Hydroxylated metabolites |  | Details |
| Zolpidem DB00425 | | Cytochrome P450 3A4 / Cytochrome P450 1A2 / Cytochrome P450 2D6 / Cytochrome P450 2C9 / Cytochrome P450 2C19 | methoxyzolpidem |  | Details |
| Zonisamide DB00909 |  | Cytochrome P450 3A4 | 2-sulfamoylacetylphenol |  | Details |
| Zonisamide DB00909 | | Not Available | N-acetyl zonisamide |  | Details |
| Zopiclone DB01198 |  | Cytochrome P450 2C8 / Cytochrome P450 3A4 / Cytochrome P450 2C9 | N-desmethylzopiclone |  | Details |
| Zopiclone DB01198 | | Cytochrome P450 2C9 | Zopiclone N-oxide |  | Details |
| Zopiclone DB01198 | | Prostaglandin G/H synthase 1 | Carbon dioxide |  | Details |
| Zopiclone DB01198 | | Cytochrome P450 2C8 / Cytochrome P450 3A4 | zopiclone-N-oxide |  | Details |
| Zotepine DB09225 |  | Cytochrome P450 1A2 | 2-OH-zotepine |  | Details |
| Zotepine DB09225 | | Cytochrome P450 3A4 | Zotepine N-oxide |  | Details |
| Zotepine DB09225 | | Cytochrome P450 1A1 / Cytochrome P450 1A2 / Cytochrome P450 3A4 / Cytochrome P450 2D6 / Cytochrome P450 2C19 | 3-OH-zotepine |  | Details |
| Zotepine DB09225 | | Cytochrome P450 1A1 / Cytochrome P450 1A2 / Cytochrome P450 2B6 / Cytochrome P450 3A4 / Cytochrome P450 3A5 | Zotepine -oxide |  | Details |
| Zotepine DB09225 | | Cytochrome P450 1A1 / Cytochrome P450 1A2 / Cytochrome P450 3A4 / Cytochrome P450 3A5 / Cytochrome P450 2B6 / Cytochrome P450 2C19 | Norzotepine |  | Details |
| α-D-galactose DBMET02088 |  | Galactokinase | galactose-1-phosphate |  | Details |
| α-Hydroxy sertraline ketone DBMET02916 |  | Not Available | Sertraline carbamoyl-O-glucuronide |  | Details |