B-cell Childhood Acute Lymphoblastic Leukemia (DBCOND0030125)

Identifiers

Synonyms

ALL, Childhood B-Cell / B-Cell Pediatric ALL / Pediatric ALL, B Cell / B-Cell ALL, Childhood / Childhood B Acute Lymphoblastic Leukemia

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04746209	Blinatumomab After TCR Alpha Beta/CD19 Depleted HCT	Blinatumomab	treatment	2	recruiting
NCT04604691	Blinatumomab in Pediatric B-cell Acute Lymphoblastic Leukemia (ALL) With Minimal Residual Disease (MRD)	Blinatumomab	treatment	1	recruiting
NCT02227108	Study in Pediatrics With Relapsed or Refractory Pediatric Acute Lymphoblastic Leukemia (pALL) or Lymphoblastic Lymphoma	Moxetumomab pasudotox	treatment	2	terminated
NCT04173988	Study of alloCART-19 Cell Therapy in Pediatric Patients With Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia	Cyclophosphamide Fludarabine	treatment	0	active_not_recruiting
NCT05366218	Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia	Tafasitamab	treatment	1 / 2	recruiting
NCT00101205	Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma	Etoposide Oxaliplatin	treatment	1	terminated
NCT00058461	Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia	Carboplatin Cytarabine Etoposide Filgrastim Ifosfamide Methotrexate Rituximab	treatment	2	terminated
NCT00873093	Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma	Asparaginase Escherichia coli Aspartic acid Bortezomib Bortezomib D-mannitol Cyclophosphamide Cytarabine Doxorubicin Etoposide Filgrastim Hydrocortisone Leucovorin Methotrexate Pegaspargase Prednisone Vincristine	treatment	2	completed
NCT00382109	Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission	Cyclophosphamide Methotrexate Sirolimus Tacrolimus Thiotepa	treatment	3	completed
NCT01093586	Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies	Antilymphocyte immunoglobulin (horse) Antithymocyte immunoglobulin (rabbit) Busulfan Cyclophosphamide Cyclosporine Methylprednisolone Methylprednisolone hemisuccinate Mycophenolate mofetil	treatment	2	completed
NCT00381680	Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia	Asparaginase Escherichia coli Aspartic acid Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Etoposide Filgrastim Leucovorin Mercaptopurine Methotrexate Pegaspargase Prednisone Sulfate ion Vincristine	treatment	3	completed
NCT00898404	Response or Resistance to Chemotherapy in Young Patients With Acute Lymphoblastic Leukemia Treated With Methotrexate	No drug interventions	Not Available	Not Available	completed
NCT01625143	Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia	No drug interventions	Not Available	Not Available	completed
NCT00061945	Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia	Acyclovir Alemtuzumab Allopurinol Asparaginase Escherichia coli Cyclophosphamide Cytarabine Daunorubicin Dexamethasone Filgrastim Imatinib Leucovorin Mercaptopurine Methotrexate Sulfamethoxazole Trimethoprim Vincristine	treatment	1 / 2	completed
NCT01540578	Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic Leukemia	No drug interventions	Not Available	Not Available	completed
NCT01990807	Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia	Idarubicin	treatment	4	unknown_status
NCT00052520	Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation	Aldesleukin Therapeutic allogeneic lymphocytes	treatment	1 / 2	completed
NCT00867529	Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma	Rituximab	treatment	2	completed
NCT00103285	Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia	Asparaginase Escherichia coli Calcium Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Leucovorin Levoleucovorin Mercaptopurine Methopterin Methotrexate Pegaspargase Sulfate ion Tioguanine Vincristine	treatment	3	completed
NCT01403415	Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma	Asparaginase Escherichia coli Dexamethasone Menthol Methopterin Methotrexate Mitoxantrone Pegaspargase Sirolimus Sulfate ion Temsirolimus Vincristine	treatment	1	completed
NCT01190930	Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma	Asparaginase Escherichia coli Calcium Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Leucovorin Levoleucovorin Mercaptopurine Methopterin Methotrexate Pegaspargase Sulfate ion Tioguanine Vincristine	treatment	3	active_not_recruiting
NCT00866307	Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia (Closed to Accrual 4-22-2011)	Asparaginase Escherichia coli Cortisone Cyclophosphamide Cytarabine Daunorubicin Dexamethasone Doxorubicin Mercaptopurine Methopterin Methotrexate Pegaspargase Prednisone Sulfate ion Tioguanine Vincristine	treatment	1	completed
NCT00671034	Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia	Asparaginase Escherichia coli Benzalkonium Calaspargase pegol Carbonate ion Cortisone Cyclophosphamide Cytarabine Daunorubicin Dexamethasone Doxorubicin Mercaptopurine Methopterin Methotrexate Pegaspargase Prednisone Sulfate ion Tioguanine Vincristine	treatment	3	completed
NCT00075725	Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia	Asparaginase Escherichia coli Calcium Cortisone Cyclophosphamide Cytarabine Daunorubicin Dexamethasone Doxorubicin Leucovorin Levoleucovorin Mercaptopurine Methopterin Methotrexate Pegaspargase Prednisone Sulfate ion Tioguanine Vincristine	treatment	3	completed
NCT00437060	Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia	No drug interventions	Not Available	Not Available	completed
NCT01595048	Combination Chemotherapy With or Without Rituximab in Treating Younger Patients With Stage III-IV Non-Hodgkin Lymphoma or B-Cell Acute Leukemia	Cyclophosphamide Cytarabine Doxorubicin Etoposide Hydrocortisone Leucovorin Methotrexate Methylprednisolone Prednisone Rituximab Vincristine	treatment	2 / 3	active_not_recruiting