Connective Tissue Disorders (DBCOND0030834)

Identifiers

Synonyms
Connective Tissue Disorder / Connective Tissue Diseases / Connective Tissue Disease / Connective tissue disorders / Disease of connective tissues (disorder) / Connective tissue disorders NEC / Connective tissue disorder NOS

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Cyclosporine
A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06499233
Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Diseaseprevention4recruiting
NCT04084678
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PHtreatment3terminated
NCT00491309
Exercise and Respiratory Therapy in Patients With Rheumatoid Arthritis / Collagenosis and Pulmonary HypertensionNo drug interventionstreatmentNot Availableunknown_status
NCT00001641
Study of Heritable Connective Tissue DisordersNo drug interventionsNot AvailableNot Availablecompleted
NCT01042158
A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosistreatment4completed
NCT01387035
Early Diagnosis of Pulmonary Hypertension in Patients With Inflammatory Rheumatic Connective Tissue DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT01809574
The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01764594
Safety Study of CDP7657 in Patients With Systemic Lupus ErythematosusNot Available1completed
NCT00864201
A Study to Evaluate the Use of Bosentan in Patients With Exercise Induced Pulmonary Arterial Hypertension Associated With Connective Tissue Diseasetreatment3unknown_status
NCT01488708
On Open-Label Study in Participants With Systemic Lupus Erythematosustreatment3terminated
NCT01205438
A Study of LY2127399 in Participants With Systemic Lupus Erythematosustreatment3completed
NCT01424033
A Clinical Trial for CTD-ILD Treatmenttreatment2 / 3terminated
NCT01093911
Safety Study of CDP7657 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus (SLE)Not Available1completed
NCT01196091
A Study of LY2127399 in Participants With Systemic Lupus Erythematosustreatment3completed
NCT01208792
Auto-immunity and Pulmonary Arterial HypertensionNo drug interventionsdiagnosticNot Availablecompleted
NCT05998759
Telitacicept for the Treatment of Connective Tissue Disease-associated Thrombocytopeniatreatment2recruiting
NCT03626688
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patientstreatment3recruiting
NCT03683186
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extensiontreatment3enrolling_by_invitation
NCT04664478
Gene First Approach to Connective Tissue DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT06104228
129 Xenon MRI As a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH)No drug interventionsdiagnostic2recruiting
NCT00522002
CLUE Study: Connective Tissue Disease Leg Ulcer Etiology StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04095351
Connective Tissue Diseases and Lung ManifestationsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05980728
Connective Tissue Disease Patients With Pulmonary HypertensionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04297371
Early Detection of Cardiac Impairment and Prediction of RV Hypertrophy in Patients With CTDNo drug interventionsNot AvailableNot Availablecompleted
NCT01656278
An MRI-guided Treatment Strategy to Prevent Disease Progression in Patients With Rheumatoid ArthritisNo drug interventionstreatmentNot Availablecompleted
NCT00802607
Collection of Tissue Specimens for Analysis and Establishment of Cell CulturesNo drug interventionsNot AvailableNot Availablecompleted
NCT04993885
Avatrombopag in the Treatment of Adult Immune Thrombocytopenia With Autoantibodiestreatment2recruiting
NCT04169100
Novel Form of Acquired Long QT Syndromeprevention4recruiting
NCT00005675
Oral Type I Collagen for Relieving Sclerodermatreatment2completed
NCT04918524
The Clinical Features and Pregnancy Outcomes of CTD PatientsNot AvailableNot Availablerecruiting
NCT04928586
Immunosuppressant Combined With Pirfenidone in CTD-ILDtreatment4active_not_recruiting
NCT02392130
A Clinical Trial to Assess the Potential of LEO 130852A Gel to Reduce Steroid Induced Skin Atrophy on Healthy Skinother1completed
NCT00001330
Study of Silicone-Associated Connective Tissue DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT00004357
Absorption of Corticosteroids in Children With Juvenile Dermatomyositistreatment2completed
NCT04428957
Telemonitoring of Treatment Effects in Connective Tissue Disease-associated Interstitial Lung Disease (TEL-CTD-ILD)No drug interventionsotherNot Availableunknown_status
NCT03929120
Allogeneic Bone Marrow Mesenchymal Stem Cells for Patients With Interstitial Lung Disease (ILD) & Connective Tissue Disorders (CTD)No drug interventionstreatment1completed
NCT04915482
TPO-RAs Combined With Anti-CD20 Antibody in the Treatment of Adult Immune Thrombocytopenia With AutoantibodiesNo drug interventionstreatment2 / 3recruiting
NCT04171362
The Effect of Connective Tissue Massage in Patients With MigraineNo drug interventionstreatmentNot Availablecompleted
NCT04582292
Laryngeal Manifestations of Connective Tissue DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT03565601
Prognostic Value of Anti-Ro52 Antibodies in Connective Tissue Diseases (a-Ro52)No drug interventionsNot AvailableNot Availableunknown_status
NCT06574581
ADSCs Therapy in Patients With CTD-ILDNo drug interventionstreatment1 / 2recruiting
NCT06458803
Efficacy and Safety of Eltrombopag for Refractory Thrombocytopenia Associated With Connective Tissue DiseaseNot AvailableNot Availablecompleted
NCT06455384
The Genetics Navigator: Evaluating a Digital Platform for Genomics Health ServicesNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT02682511
Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertensiontreatment2recruiting
NCT05505409
Efficacy and Safety of Pirfenidone in CTD-ILDtreatment4recruiting
NCT05665556
REgistry of Pulmonary Arterial Hypertension Associated With CONNECTIVE Tissue Diseases (RECONNECTIVE)No drug interventionsNot AvailableNot Availablerecruiting
NCT02768259
Prevalence of Pulmonary Arterial Hypertension in Patients With Connective Tissue Diseases in Egyptian PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03494036
Effect of Synbiotic on Immune Response, Gut Permeability and Microbiota in Patient With Connective Tissue DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT05516758
A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritistreatment2active_not_recruiting
NCT03214263
Identification of New Biomarkers to Promote Personalized Treatment of Patients With Inflammatory Rheumatic DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT03446339
Pulmonary Hypertension Screening for Rheumatology Patients (SOPHIE)No drug interventionsNot AvailableNot Availableunknown_status
NCT03337165
Autologous Tolerogenic Dendritic Cells for Treatment of Patients With Rheumatoid ArthritisNo drug interventionstreatment1completed
NCT03688191
Study of Sirolimus in CTD-TP in Chinatreatment4unknown_status
NCT05440240
Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's ContractureNo drug interventionstreatment4recruiting
NCT04702295
ERN ReCONNET Study on COVID-19 Vaccination in Rare and Complex Connective Tissue Disease (VACCINATE)No drug interventionsNot AvailableNot Availableunknown_status
NCT05065814
Connective Tissue Diseases and Vitamin D DeficiencyNo drug interventionsotherNot Availableunknown_status
NCT04197050
Effect of Sacubitril/Valsartan on Reduced Right Ventricular Ejection Fraction in Patients With CTDtreatment4unknown_status
NCT04896138
University of Virginia Natural History StudyNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03847753
Exploring the Comorbidity Between Mental Disorders and General Medical ConditionsNo drug interventionsNot AvailableNot Availablecompleted
NCT00470327
A Study of the Natural Progression of Interstitial Lung Disease (ILD)No drug interventionsNot AvailableNot Availablerecruiting
NCT04398628
ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT01379118
Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT01808196
Testing Effectiveness of Losartan in Patients With EoE With or Without a CTDtreatment2completed
NCT00076830
Evaluation and Treatment of Patients With Connective Tissue DiseaseNo drug interventionsNot AvailableNot Availablecompleted