| Octreotide | A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors. |
| Esmolol | A cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension. |
| Betaxolol | A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically). |
| Metoprolol | A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. |
| Atenolol | A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients. |
| Diltiazem | A calcium channel blocker used to treat hypertension and to manage chronic stable angina. |
| Timolol | A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. |
| Digoxin | A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. |
| Bendroflumethiazide | A diuretic used to suppress lactation and to treat hypertension and edema. |
| Sotalol | A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter. |
| Carteolol | A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. |
| Propranolol | A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. |
| Clonidine | An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. |
| Labetalol | An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. |
| Bisoprolol | A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension. |
| Dexmedetomidine | An alpha-2 agonist used for sedation during various procedures. |
| Verapamil | A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. |
| Galantamine | A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. |
| Tizanidine | An alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity. |
| Sufentanil | An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain. |
| Donepezil | An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia. |
| Pindolol | A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation. |
| Methyldopa | An alpha-2 adrenergic agonist used to treat hypertension. |
| Rivastigmine | A cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's. |
| Guanfacine | An alpha-2A adrenergic receptor agonist used to treat ADHD. |
| Amiodarone | A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. |
| Carvedilol | A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. |
| Propafenone | A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. |
| Acebutolol | A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. |
| Nadolol | A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension. |
| Levobunolol | A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Metipranolol | A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Penbutolol | A beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents. |
| Dronedarone | An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. |
| Nebivolol | A beta blocking agent used to treat hypertension and aid in the management of heart failure. |
| Lucinactant | Intended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS. |
| Calfactant | A lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants. |
| Pasireotide | A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. |
| Beractant | A pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants. |
| Lanreotide | A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. |
| Crizotinib | A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive. |
| Fingolimod | A sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19. |
| Ceritinib | An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib. |
| Ivabradine | A HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients. |
| Poractant alfa | A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. |
| Bretylium | A norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias. |
| Lacosamide | An antiepileptic drug used to treat partial onset seizures in adults. |
| Tofacitinib | A Janus kinase (JAK) inhibitor used to treat rheumatoid and psoriatic arthritis, and ulcerative colitis. It is not recommended to be combined with biologic therapies or potent immunosuppressants like cyclosporine or azathioprine. |
| Agmatine | Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,... |
| Amlodipine | A calcium channel blocker used to treat hypertension and angina. |
| Aranidipine | Aranidipine has been used for many years to treat angina pectoris and hypertension. |
| Azelnidipine | For the treatment of hypertension. |
| Barnidipine | Indicated for the treatment of mild to moderate essential hypertension and management of chronic stable angina. |
| Bencyclane | A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels. |
| Benidipine | Benidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris. |
| Bepridil | For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). |
| Bioallethrin | Bioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin. |
| Carboxyamidotriazole | Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others. |
| Caroverine | Not Annotated |
| Cilnidipine | Cilnidipine is indicated for the management of hypertension for end-organ protection. It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnidipine has been... |
| Cinnarizine | For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins. |
| Clevidipine | A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. |
| Cyclandelate | A vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis. |
| Darodipine | Darodipine is a calcium channel blocker. |
| Dexniguldipine | Not Annotated |
| Dexverapamil | Not Annotated |
| Dotarizine | Investigated for use/treatment in migraine and cluster headaches. |
| Efonidipine | For the treatment of hypertension. |
| Emopamil | Prevents renal injury after warm & cold ischemia. |
| Eperisone | Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression... |
| Ethosuximide | An anticonvulsant used to treat petit mal seizures. |
| Felodipine | A calcium channel blocker used to treat hypertension. |
| Fendiline | Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. |
| Fish oil | A source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement. |
| Flunarizine | A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. |
| Fluspirilene | An antipsychotic agent used in the treatment of schizophrenia. |
| Gallopamil | Gallopamil has been used in trials studying the treatment of Asthma. |
| Isradipine | A dihydropyridine calcium channel blocker used for the treatment of hypertension. |
| Lacidipine | Indicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors . |
| Lamotrigine | A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. |
| Lercanidipine | For the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome |
| Lidoflazine | Not Annotated |
| Lomerizine | Used to treat migraines. |
| Loperamide | A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis. |
| Magnesium sulfate | A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. |
| Manidipine | For the treatment of hypertension. |
| Levomenthol | An organic compound used to treat mild to moderate muscle and joint pain. |
| Methsuximide | A succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures. |
| Mibefradil | For the treatment of angina and high blood pressure. |
| Naftopidil | Naftopidil has been investigated for the treatment of Disorder of Urinary Stent. |
| Nicardipine | A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. |
| Nifedipine | A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. |
| Niguldipine | Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. |
| Niludipine | Niludipine is a calcium channel blocker. |
| Nilvadipine | For the management of vasospastic angina, chronic stable angina and hypertension. |
| Nimesulide | For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. |
| Nimodipine | A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. |
| Nisoldipine | A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. |
| Nitrendipine | For the treatment of mild to moderate hypertension |
| Nylidrin | A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. |
| Otilonium | Not Annotated |
| Penfluridol | Not Annotated |
| Perhexiline | For the management of severe angina pectoris. |
| Pinaverium | A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. |
| Pregabalin | An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants. |
| Prenylamine | Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. |
| Seletracetam | Investigated for use/treatment in epilepsy. |
| Terodiline | Not Annotated |
| Tetrahydropalmatine | Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). |
| Tetrandrine | Not Annotated |
| Tolfenamic acid | In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. |
| Tranilast | For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. |
| Trimebutine | A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. |
| Trimethadione | An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures. |
| Vinpocetine | Vinpocetine has been investigated for the treatment of Epilepsy. |
| WIN 55212-2 | WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It... |
| Zonisamide | A sulfonamide anticonvulsant used to treat partial seizures. |
| Midodrine | An alpha-adrenergic antagonist used to treat orthostatic hypotension. |
| Regorafenib | A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma. |
| Alprenolol | For the treatment of hypertension, angina, and arrhythmia |
| Anisodamine | Anisodamine has been investigated for the treatment of Intestinal Diseases. |
| Arotinolol | Artinolol was introduced to be used as an antihypertensive agent since 1986. It has been studied for other functions like tremor control for patients with Parkinson disease and it is... |
| Befunolol | Used in the management of open angle glaucoma. PMID: 12480285. |
| Bevantolol | For the treatment of angina pectoris and hypertension. |
| Bopindolol | For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation. |
| Bucindolol | Bucindolol has been investigated in Heart Failure. |
| Bufuralol | Bufuralol is a new, non-selective -adrenoceptor blocking agent. |
| Bupranolol | Used to manage hypertension and tachycardia. Also used to treat glaucoma. |
| Celiprolol | Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. |
| Cloranolol | Not Annotated |
| Epanolol | Epanolol is an beta blocker. |
| Esatenolol | Esatenolol is a beta blocker. |
| Indenolol | Indenolol is a drug of the beta-adrenergic blocker class. |
| Landiolol | Landiolol has been used in trials studying the treatment of Pharmacokinetics/Dynamics Study. |
| Levobetaxolol | Used in the treatment of open-angle glaucoma and ocular hypertension [FDA Label]. |
| Mepindolol | Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker. |
| Oxprenolol | A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety. |
| Practolol | Used in the emergency treatment of cardiac arrhythmias. |
| Talinolol | Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder. |
| Tertatolol | Tertatolol is a beta blocker. |
| Alfentanil | An opioid agonist used to induce and maintain anesthesia, as well as an analgesic. |
| Fentanyl | An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. |
| Remifentanil | An opioid analgesic used in anesthesia. |