Propiophenones

Name
Propiophenones
Accession Number
DBCAT001282
Description

Propiophenone (ethyl phenyl ketone, structural formula C6H5COCH2CH3) and its derivatives. They are commonly used in perfumes and pharmaceuticals.

Drugs
DrugDrug Description
PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
ElafibranorInvestigated for use/treatment in atherosclerosis and diabetes mellitus type 2.
SofalconeInvestigated for use/treatment in gastroenteritis and ulcers.
TolperisoneInvestigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.
RadafaxineRadafaxine has been used in trials studying the treatment of Depressive Disorder, Major.
OxyfedrineNot Annotated
EtafenoneEtafenone is a vasodilator.
DihydroxymethoxychalconeCardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human...
IsoliquiritigeninIsoliquiritigenin is a precursor to several flavonones in many plants.
PhloretinPhloretin is a natural dihydrochalcone found in apples and many other fruits.
Hesperidin methylchalconeNot Annotated
Drugs & Drug Targets
DrugTargetType
PropafenoneSodium channel protein type 5 subunit alphatarget
PropafenonePotassium voltage-gated channel subfamily H member 2target
PropafenoneCytochrome P450 1A2enzyme
PropafenoneCytochrome P450 2D6enzyme
PropafenoneCytochrome P450 3A4enzyme
PropafenoneP-glycoprotein 1transporter
PropafenoneBeta-1 adrenergic receptortarget
PropafenoneBeta-2 adrenergic receptortarget
ElafibranorPeroxisome proliferator-activated receptor alphatarget
ElafibranorPeroxisome proliferator-activated receptor deltatarget
ElafibranorPeroxisome proliferator-activated receptor gammatarget
SofalconeCarbonyl reductase [NADPH] 1enzyme
TolperisoneCytochrome P450 1A2enzyme
PhloretinHTH-type transcriptional regulator TtgRtarget