Nocturia (DBCOND0004540)

Identifiers

Synonyms
Nocturnal frequency / Nycturia

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Desmopressin
A synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia.
Flavoxate
A muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia.
Oxybutynin
An antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05298384
Pathophysiologic Study to Understand and Possibly Treat NocturiaNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT01530451
Clinical Trial of Desmopressin on Nocturia in Obstructive Sleep Apnoea Patientstreatment3terminated
NCT02151253
Cross-over Study of Armodafinil Treatment of Daytime Sleepiness Associated With Treated Nocturiatreatment2 / 3completed
NCT01694498
Comparative Trial to Investigate the Efficacy and Safety of Desmopressin for the Treatment of Nocturia in Adult Mentreatment2completed
NCT01222598
A Study of Minirin Melt in Patients With NocturiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04433897
Effect of Hormonal Replacement Therapy on Nocturia in Postmenopausal WomenNo drug interventionsNot AvailableNot Availablerecruiting
NCT01259128
Study to Investigate the Safety and Pharmacokinetics of SER120 Nasal Spray in Elderly Patients With NocturiaNo drug interventionstreatment3completed
NCT03051009
Trial Investigating the Long Term Safety and Tolerability of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Subjectstreatment3completed
NCT01223937
Investigation of the Superiority Effect of Desmopressin to Placebo in Terms of Night Voids Reduction in Nocturia Adult Female Patientstreatment3completed
NCT00824200
Behavior and Exercise Versus Drug Treatment in Men With Nocturia (BEDTiMe)treatment4completed
NCT01184859
Comparative Trial to Investigate the Dose-Response of 4 Different Dose Levels of Minirin Melt and Placebotreatment2completed
NCT02904759
Trial of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Male Subjectstreatment3completed
NCT01486706
Efficacy and Safety of Gabapentin in Treating Overactive Bladdertreatment2 / 3completed
NCT02262936
Comparison Between Desmopressin and Fesoterodine for Treatment of Night Time Voiding in Women Aged 65 and Oldertreatment2 / 3terminated
NCT01816724
Spanish (Spain) Validation of a Specific Symptomatic Questionnaire for Patients With NocturiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03883724
Impact of Behavioral Treatment of Insomnia on Nighttime Urine ProductionNo drug interventionsotherNot Availablecompleted
NCT04266496
Discovering the Effect of Venous Insufficiency on NocturiaNo drug interventionsdiagnosticNot Availablecompleted
NCT04480658
Effectiveness of Bryophyllum in Nocturia-TherapyNo drug interventionstreatmentNot Availablecompleted
NCT02410135
Myrbetriq™ (Mirabegron) to Improve Disordered Sleep in Subjects With Lower Urinary Tract Symptoms (LUTS)Not AvailableNot Availablecompleted
NCT01520948
Behavioral Therapy to Treat Urinary Symptoms in Parkinson DiseaseNo drug interventionstreatment3completed
NCT02359448
Melatonin for Nocturia in Parkinson's Diseasetreatment2unknown_status
NCT01779466
Daytime Impact Sleep Studytreatment2terminated
NCT00826527
Evaluation of Solifenacin in the Treatment of OAB Symptoms in Patients Who Have Successfully Undergone GreenLight Photoselective Vaporization of the Prostate (PVP)treatment4unknown_status
NCT01330927
Dose Response Study of VA106483 in Males With Nocturia and Benign Prostatic Hypertrophy (BPH)No drug interventionstreatment1completed
NCT02068560
The Effect of Gender on Antidiuresis - Evaluated by Graded Low Dose Desmopressin Infusionbasic_scienceNot Availablecompleted
NCT02637960
Efficacy Study of Fedovapagon for Nocturia in Men With Benign Prostatic Hyperplasia (BPH)treatment2 / 3completed
NCT03623880
Enhancing Behavioral Treatment for Women With Pelvic Floor DisordersNo drug interventionstreatmentNot Availablecompleted
NCT01900704
Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia - DB4No drug interventionstreatment3completed
NCT05368246
Safety and Performance of UCon for the Treatment of the Symptoms of Overactive Bladder (OAB) / Bowel Dysfunction (BD)No drug interventionstreatmentNot Availablecompleted
NCT02835846
Investigation of the Effect of the Female Urinary Microbiome on Incontinencetreatment4completed
NCT02961114
Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate HypertrophyNo drug interventionstreatment1 / 2withdrawn
NCT04357223
NOGO for an Overactive Bladdertreatment2unknown_status
NCT00879138
Efficacy and Safety of VA106483 in Elderly MalesNo drug interventionsNot Available1 / 2completed
NCT01038843
Efficacy Study of VA106483 in Males With Nocturia.No drug interventionstreatment2completed
NCT00477490
Efficacy and Safety of Desmopressin Melt for the Treatment of Nocturiatreatment3completed
NCT04528784
Feasibility Study of Transcutaneous Tibial Nerve Stimulation for Urinary Symptoms in People With Multiple SclerosisNo drug interventionstreatmentNot Availablecompleted
NCT05414279
Validation of Capillary Serum Sodium LevelsNo drug interventionsbasic_scienceNot Availablecompleted
NCT05222477
Abdominal Muscle Exercises on Nocturia and Sleep Quality in Women With Type 2 DiabetesNo drug interventionstreatmentNot Availablecompleted
NCT03928197
Discovering the Effect of Venous Insufficiency on Nocturia (DEVINe)No drug interventionsotherNot Availablecompleted
NCT01439997
Desmopressin Melt Therapy in Nocturnal Polyuria Patients: Pharmacodynamic Studytreatment4completed
NCT00700583
Alpha-blocker Plus Diuretic Combination Therapy as Second-line Treatment for Nocturia in MentreatmentNot Availablecompleted
NCT05404828
TUCSON Study: Tackling Underlying Causes Of Sleep Related Nocturia NocturiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00937378
Treatment of Patients With Nocturia (Non-PK Study)No drug interventionstreatment3completed
NCT05562388
Mandibular Advancement Device and Changes in NocturiaNo drug interventionstreatmentNot Availablerecruiting
NCT01357356
Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With NocturiaNo drug interventionstreatment2 / 3completed
NCT01262456
Investigation of the Superiority Effect of Orally Disintegrating Desmopressin Tablets to Placebo in Terms of Night Voids Reduction in Nocturia Adult Male Patientstreatment3completed
NCT01576900
The Effect of Combined Systematized Behavioural Modification Education Program (SyBeMeP) With DDAVP in Patients With NocturiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01684800
Comparative Trial to Investigate the Efficacy and Safety of Desmopressin for the Treatment of Nocturia in Adult Womentreatment2completed
NCT00937859
Treatment of Patients With NocturiaNo drug interventionstreatment3completed
NCT05874375
UCon Treatment of Overactive Bladder (OAB) in MalesNo drug interventionstreatmentNot Availablerecruiting
NCT00615836
An Extension Study Investigating the Efficacy and Safety of a Fast-Dissolving ("Melt") Formulation of Desmopressin for the Treatment of Nocturia in Adultstreatment3completed
NCT03201419
A Trial to Investigate Efficacy, Safety and Tolerability of FE 201836 for Nocturia Due to Nocturnal Polyuria in Adultstreatment2completed
NCT00793819
A Study of Silodosin 8 mg Daily for the Treatment of Nocturia in Men With Benign Prostatic Hyperplasiatreatment2completed
NCT02440841
Study in Healthy Male Subjects to Evaluate the Effect of Itraconazole and Rifampicin on the PK of Fedovapagontreatment1completed
NCT01212224
A Study of Minirin Melt in Patients With NocturiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00879216
VA106483 and Alpha Blocker Interaction Study in Elderly MalesNo drug interventionstreatment1completed
NCT02878096
Bioavailability of [14C]-SK-1404 ADME & IV Microtracer Studybasic_science1completed
NCT01656239
Dose Range Finding Study of Fedovapagon in Men With Nocturiatreatment2completed
NCT03043222
Innovative Minimally Invasive Options in Treatment of Urinary Problems Related to Prostate Enlargement (BPH) in MenNo drug interventionstreatmentNot Availablewithdrawn
NCT05604222
Effect of Behavioral Sleep Intervention on Lower Urinary Tract Symptoms in Older Womentreatment4recruiting
NCT05090722
A Pilot Study to Evaluate PureWick for NocturiaNo drug interventionstreatmentNot Availablesuspended
NCT01018225
Exploratory Study Evaluating the Effects of Darifenacin on Nocturia, Sleep and Daytime WakefulnessNot Available4withdrawn
NCT05419830
Sleep, Hypertension, and Nocturia: a Multicomponent Approach for Comorbid IllnessesNo drug interventionsotherNot Availablecompleted
NCT02646826
Paxerol™ for Treatment of Nocturia - A Phase II Placebo-Controlled TrialNo drug interventionstreatment2completed
NCT04891926
Hormonal Influences on DiuresisNo drug interventionstreatmentNot Availablecompleted
NCT06091566
Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)No drug interventionstreatmentNot Availablerecruiting
NCT05597020
A Post Approval Study to Investigate the Efficacy of Daridorexant in Subjects With Insomnia and Comorbid Nocturiatreatment4completed
NCT00981682
Long Term Safety Assessment of SER120 in Patients With Nocturiatreatment3completed
NCT02905682
Trial of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Female Subjectstreatment3completed
NCT02106182
Efficacy and Safety of Silodosin on Nocturia for Patients With Benign Prostatic Hyperplasiatreatment4completed
NCT02060331
Severe Pelvic Organ Prolapse and Post-Obstructive Diuresis (SOPPO) Pilot StudyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03089073
Study of Minirin Melt® in Adult Patients With NocturiaNot AvailableNot Availableterminated
NCT03810027
Prevalence and Risk Factors Nocturnal Polyuria in Female OABNo drug interventionsNot AvailableNot Availablecompleted
NCT02396160
The Effect of Urox™ in the Treatment of Overactive Bladder and Urinary IncontinenceNo drug interventionstreatmentNot Availablecompleted
NCT01171391
VA106483 Dose Response in FemalesNo drug interventionstreatment1completed
NCT06110091
Multi-center Trial to Improve Nocturia and Sleep in Older AdultsNo drug interventionstreatmentNot Availablerecruiting
NCT05464589
Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in AdultsNo drug interventionstreatmentNot Availablecompleted
NCT06508944
Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Womentreatment4active_not_recruiting
NCT04526340
Food and Salt Handling in DiuresisNo drug interventionspreventionNot Availablecompleted
NCT00922740
VA106483 Dose Response Study in Elderly MalesNo drug interventionstreatment1completed
NCT01552395
A Study of Minirin Melt in 24 Months Treatment in Patients With NocturiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00902655
Desmopressin in the Treatment of Mixed Nocturia With Nocturnal Polyuria and Low Nocturnal Bladder Capacitytreatment4completed
NCT05300308
Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04305743
Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin Atreatment4recruiting
NCT01552343
Study Investigating the Impact Burden of Nocturia Using the Nocturia Impact Diarytreatment3completed