Retinal Vein Occlusion (DBCOND0000674)

Identifiers

Synonyms
Occlusion Retinal Vein / Retinal-vein occlusion / Retinal Vein Occlusions(RVO) / Retinal Vein Occlusion (RVO) / Retinal Vein Occlusions / Retinal vein occlusion / Occlusion of retinal vein (disorder) / Retinal vein thrombosis / Thrombosis retinal vein / Thrombosis of retinal vein (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Aflibercept
A vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy, and metastatic colorectal cancer
Ranibizumab
A recombinant humanized monoclonal antibody and VEGF-A antagonist used for the management of macular edema after retinal vein occlusion, age-related macular degeneration (wet), and diabetic macular edema.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04128150
High Resolution Retina ImagingNo drug interventionsNot AvailableNot Availableunknown_status
NCT01496625
National Eye Institute Biorepository for Retinal DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT06439576
Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)Not AvailableNot Availablerecruiting
NCT04008121
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodiumdiagnostic0not_yet_recruiting
NCT01568021
Post Market Surveillance of OZURDEX® for Branch Retinal Vein Occlusion (BRVO) and Central Retinal Vein Occlusion (CRVO)No drug interventionsNot AvailableNot Availablecompleted
NCT00942864
Effect of Intravitreal Ranibizumab Injection With Retinal Vein Occlusion (RVO)treatment3completed
NCT00805064
Combined Triple Procedure in Retinal Vein Occlusion (RVO)treatment3completed
NCT00804102
Transcorneal Electrical Stimulation Therapy for Retinal DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT00101764
Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorderstreatment1completed
NCT06572553
Evaluation of Therapeutic Efficacy of Faricimab for Clinical AMD, DME, and RVO Patientstreatment2 / 3recruiting
NCT06416241
Intravitreal Aflibercept for Macular Edema Due to Central Retinal Vein Occlusiontreatment4completed
NCT06176963
A Study to Evaluate the Usability of the SB11 PFS in Subjects With Wet AMD or Macular Oedema Secondary to RVOtreatment2completed
NCT05496530
Custom Needle Preparation for Suprachoroidal Steroid Injection (One Year Results)treatmentNot Availableunknown_status
NCT04592419
A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO)treatment3completed
NCT04563299
Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injectionstreatment4terminated
NCT04505618
Optical Coherence Tomography Angiography in Subjects With Retinal Vascular DiseaseNo drug interventionsscreeningNot Availablerecruiting
NCT04395859
Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic AgentsNo drug interventionsNot AvailableNot Availablecompleted
NCT04140448
Ultra-wide-field Fluorescein Angiography in Patients With Macular Edema Secondary to Retinal Vein OcclusionNot AvailableNot Availablerecruiting
NCT03908307
Evaluation of OZURDEX® in Patients With Macular Edema Secondary to Retinal Vein Occlusion in Chinatreatment4completed
NCT03790852
Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVOtreatment1terminated
NCT03525132
Study of the Retinal Vascularization by Laser Doppler Velocimetry Coupled With an Adaptive Optics Camera ( AO-LDV)No drug interventionssupportive_careNot Availableunknown_status
NCT03489915
Correlation Between the Visual Acuity & the OCT Pattern of Macular Edema Secondary to RVONo drug interventionsNot AvailableNot Availableunknown_status
NCT04635800
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema PatientsNo drug interventionstreatment1completed
NCT05130385
High Resolution Optical Coherence TomographyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03038048
30g vs 33g Needle for Intravitreal InjectionsNo drug interventionstreatmentNot Availablecompleted
NCT02523339
Study of Retinal Oxygenation in Central Retinal Vein OcclusionNo drug interventionsNot AvailableNot Availablecompleted
NCT02645747
Retrospective Data Analysis of Patients Treated for Macular Edema Due to Central Retinal Vein OcclusionNot AvailableNot Availablecompleted
NCT02614937
Study of Squalamine Lactate for the Treatment of Macular Edema Related to Retinal Vein Occlusiontreatment1 / 2completed
NCT02387788
Open Label Study to Assess the Efficacy and Safety of AKB-9778 in Subjects With Macular Edema Due to RVOtreatment2completed
NCT02245516
Exploratory Study of KPI-121 Effect on Intra- or Subretinal Fluid Due to Retinal Vein Occlusion/Diabetic Macular EdematreatmentNot Availablecompleted
NCT02257333
Retinal Thrombosis and AtherosclerosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT02140411
Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema.treatment4completed
NCT01918371
A Retrospective Study of Anti-Vascular Endothelial Growth Factor (VEGF) Injections for Retinal Vein Occlusion or Diabetic Macular EdemaNot AvailableNot Availablecompleted
NCT01875770
Continuing Assessment of Patients Treated With ranibizUmab for REtinal Vein Occlusion (CAPTURE)No drug interventionsNot AvailableNot Availableterminated
NCT01809236
Efficacy and Safety of Conbercept in Macular Edema Secondary to Retinal Vein Occlusiontreatment2unknown_status
NCT01539577
A Long-Term Safety Study of OZURDEX® in Clinical PracticeNot AvailableNot Availablecompleted
NCT01411696
Retrospective Study in Patients Receiving Two or More OZURDEX® Injections for Retinal Vein Occlusion (RVO)Not AvailableNot Availablecompleted
NCT01318941
Observe the Effectiveness and Safety of Ranibizumab in Real Life SettingNot AvailableNot Availablecompleted
NCT00970957
Safety and Effectiveness of Bevacizumab Intravitreal Injections in the Treatment of Macular Edema Secondary to Retinal Vein Occlusiontreatment3completed
NCT00486018
A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion (BRAVO)treatment3completed
NCT00211354
Treatment of Retinal Vein Occlusion (RVO) With Open-Label Anecortave Acetate (15mg.)treatment2withdrawn
NCT00106132
Steroid Injections vs. Standard Treatment for Macular Edema Due to Retinal Blood Vessel Blockagetreatment3completed
NCT06495203
A Study to Understand the Usage of an Artificial Intelligence Technology Called DARWEN for Eye Disorders and to Find Out the Factors Influencing Treatment Frequencies in People With nAMD and RVONo drug interventionsNot AvailableNot Availablecompleted
NCT06262737
Single-center Study Measuring OSDI Dry Eye Score in Patients Undergoing an Anti-VEGF Induction ProtocolNo drug interventionsNot AvailableNot Availablerecruiting
NCT05532475
Vitreous Level Of Tumor Necrosis Factor Alpha In Patients With Retinal Vein OcclusionNo drug interventionsNot AvailableNot Availableunknown_status
NCT05345808
Efficacy of Formulated Posterior Sub Tenon Triamcinolone in Macular Edema Secondary to Non-Ischemic Retinal Vein OcclusionstreatmentNot Availablecompleted
NCT05038072
The Use of Suprachoroidal Triamcinolone Acetonide to Treat Macular Edema in Retinal Vein OcclusiontreatmentNot Availablecompleted
NCT06332690
OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVONo drug interventionsNot AvailableNot Availablerecruiting
NCT04142164
Computer-based Tutorial and Automated Speech Recognition for Intravitreal Drug InjectionsNo drug interventionsotherNot Availableunknown_status
NCT04075695
Ultra-wide-field Fluorescein Angiography in Patients With Retinal Vein OcclusionNo drug interventionsNot AvailableNot Availablerecruiting
NCT03918590
Post Intravitreal Injection Topical NSAID vs. Patchingtreatment4unknown_status
NCT03753893
Ocular Manifestations in Rheumatic DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT03762226
Influence of Systemic Parameters in Diabetic Macular Edema - LIPSIA StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03203447
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVOtreatment3terminated
NCT05133791
NIR Fluorescence Molecular Imaging of ANXV-800CW in RVO PatientsNo drug interventionstreatment1recruiting
NCT05222633
Anti-VEGF in Real-worldNot AvailableNot Availableunknown_status
NCT06343961
Intraoperative Application of Fluorescein Sodium Angiography in Vascular RetinopathyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03093701
TLC399 (ProDex) in Subjects With Macular Edema Due to Retinal Vein Occlusion (RVO)No drug interventionstreatment2completed
NCT03056079
Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercepttreatment4unknown_status
NCT02486484
Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injectiontreatment2unknown_status
NCT02503540
Peripheral and Macular Retinal Vascular Perfusion and Leakage in DME and RVOtreatment4completed
NCT02303184
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVOtreatment2completed
NCT02510885
SD-OCT AngiographyNo drug interventionsotherNot Availableterminated
NCT02126423
Resistance to Antibiotics in Patients Receiving Eye InjectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT02118831
Systemic Pharmacokinetics Following Intravitreal Injections of Anti-VEGFbasic_science1 / 2completed
NCT02088151
Selective Retinal Pigment Epithelium Laser Therapy for Macular Disease of the RetinaNo drug interventionstreatmentNot Availableterminated
NCT02040220
Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Eylea for Central Retinal Vein Occlusion (CRVO)Not AvailableNot Availablecompleted
NCT01976650
Safety and Efficacy of Dexamethasone (OZURDEX®) Intravitreal Implant in KoreaNot AvailableNot Availablecompleted
NCT01903720
A Safety and Efficacy Study of OZURDEX® in Macular Edema Associated With Branch Retinal Vein Occlusiontreatment4completed
NCT01857544
Study of Intravitreal Aflibercept Injection for Persistent CRVO-associated Macular Edema Despite Prior Anti-VEGF Therapytreatment4unknown_status
NCT01790685
Ozurdex for Retinal Vein Occlusion Study (ORVO Study)treatment2 / 3completed
NCT01717937
Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular ImagingNo drug interventionsNot AvailableNot Availableterminated
NCT01692938
Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLONo drug interventionsNot AvailableNot Availablecompleted
NCT01635803
Comparing the Effectiveness and Costs of Bevacizumab to Ranibizumab in Patients With Retinal Vein Occlusions (BRVO)treatment2 / 3unknown_status
NCT01581151
Ozurdex With Rescue Lucentis for Treating Macular Edema Secondary to Retinal Vein OcclusiontreatmentNot Availableunknown_status
NCT01571557
A Safety and Efficacy Study to Assess OZURDEX® in Patients With Macular Oedema Secondary to Retinal Vein Occlusion (RVO)Not AvailableNot Availablecompleted
NCT01573572
Extension Study to Gather Data on Effect of Macugen on the Corneal Endotheliumother4completed
NCT01468831
Minocycline to Treat Branch Retinal Vein Occlusiontreatment1 / 2completed
NCT01442064
An Extension Study to Evaluate Safety and Tolerability of Ranibizumab in Macular Edema Secondary to Retinal Vein Occlusion (Cohort 2)treatmentNot Availablecompleted
NCT01428388
Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein OcclusiontreatmentNot Availablecompleted
NCT01427751
Safety and Efficacy Study of Ozurdex® Compared to Lucentis® in Patients With Branch Retinal Vein Occlusiontreatment4completed
NCT01377597
Efficacy and Safety of Ranibizumab in Japanese Patients With Retinal Vein Occlusiontreatment3completed
NCT01123564
Efficacy and Safety of Lucentis for Clinically Significant Macular Edema Secondary to Central Retinal Vein Occlusiontreatment2unknown_status
NCT01003106
Ranibizumab DosE Comparison and the Role of LAser in REtinal Vein Occlusionstreatment1 / 2completed
NCT00770770
Fluocinolone Acetonide Intravitreal Inserts for Vein Occlusion in Retinatreatment2terminated
NCT00636493
Fluocinolone Acetonide Implant for Retinal Vein Occlusion (RVO)No drug interventionstreatment0completed
NCT00493064
To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusionstreatment2 / 3completed
NCT00485836
A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Central Retinal Vein Occlusion (CRUISE)treatment3completed
NCT00407355
Ranibizumab (Lucentis) for Macular Edema Secondary to Vein Occlusionstreatment1 / 2completed
NCT00379223
Radial Optic Neurotomy in Central Retinal Vein Occlusion : a Randomized TrialNo drug interventionstreatmentNot Availableterminated
NCT00168298
A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusiontreatment3completed
NCT00105027
The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Studytreatment3completed
NCT00071227
Eye Injections of Triamcinolone Acetonide for Retinal Blood Vessel Disorderstreatment1completed
NCT00088283
Pegaptanib Sodium Compared to Sham Injection in Patients With Recent Vision Loss Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO)treatment2completed
NCT04062370
Ranibizumab Treatment for Macular Edema Secondary to Retinal Vein Occlusiontreatment4unknown_status
NCT06213896
Detecting Eye Diseases Via Hybrid Deep Learning Algorithms From Fundus ImagesNot AvailableNot Availablecompleted
NCT05532735
Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein OcclusionNo drug interventionstreatment2active_not_recruiting
NCT05099094
VEGFA-targeting Gene Therapy to Treat Retinal and Choroidal Neovascularization DiseasesNo drug interventionstreatment0unknown_status
NCT05003258
Functional and Anatomical Outcomes of Dexamethasone Intra-vitreal Implant in Patients With Resistant Macular Edema Secondary to Retinal Vein Occlusion After Intravitreal Anti-VEGF InjectionNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04847869
Near-Infrared Light Photobiomodulation Treatment for Retinal Vein Occlusion Macular OedemaNo drug interventionstreatmentNot Availableunknown_status
NCT04707625
Vascular Endothelial Growth Factor (VEGF) Levels in Retinal Vein Occlusion (RVO) During Anti-VEGF Treatmentbasic_science4terminated
NCT04011358
Retinal Vein Occlusion and Obstructive Sleep Apnea: A Case Control StudyNo drug interventionspreventionNot Availablewithdrawn
NCT03680794
Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic RetinopathiesNo drug interventionsotherNot Availablerecruiting
NCT05675540
Artificial Intelligence Diagnostic AidNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03391219
Combined Intravitreal Injection of Bevacizumab and Fasudil Versus Bevacizumab Alone for Macular Edema Secondary to Retinal Vein Occlusion in Previously Treated Patientstreatment2 / 3unknown_status
NCT04723160
Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus PhotographNo drug interventionsNot AvailableNot Availablecompleted
NCT02880644
Ultra-wide Fluorescein Angiography in Patients With Central Retinal Vein Occlusion Treated by AfilberceptNo drug interventionsNot AvailableNot Availablecompleted
NCT02898480
Changes in the Diameter of Retinal Vessels After Remote Ischemic ConditioningNo drug interventionsbasic_scienceNot Availablecompleted
NCT03056092
Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumabtreatment4unknown_status
NCT02956330
Retrospective Study of the Safety and Efficacy of Patients With RVO in Subjects Who Completed Parent Study CLS1003-201No drug interventionsNot AvailableNot Availablecompleted
NCT02980874
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVOtreatment3terminated
NCT02521116
Comparison of Retinal Oxygenation and Retinal Vessel Diameters in Healthy Subjects and Patients With Diabetic Retinopathy or Retinal Vein Occlusion Between DVA and OxymapNo drug interventionsotherNot Availablecompleted
NCT02571972
Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME.treatment2completed
NCT02181530
Retrospective Data Collection Study in Patients With Macular Oedema Receiving OZURDEX®No drug interventionsNot AvailableNot Availablecompleted
NCT01662518
DDS-25 Gauge in Patients With Macular Edema Secondary to Retinal Vein Occlusion (RVO)No drug interventionstreatment1 / 2completed
NCT01618266
Study of Ozurdex® Treatment Practice in Patients With Macular Oedema Due to Retinal Vein OcclusionNot AvailableNot Availablecompleted
NCT01580020
Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVOtreatment4completed
NCT01566526
Retrospective Data Collection Study in Patients Receiving Two or More OZURDEX® Injections for Macular Oedema Secondary to Retinal Vein OcclusionNot AvailableNot Availablecompleted
NCT01468844
Minocycline to Treat Central Retinal Vein Occlusiontreatment1 / 2completed
NCT01449682
Efficacy of an Intravitreal DEX Implant in Retinal Vein Occlusion Following Treatment With Anti-VEGF Injections.treatment3completed
NCT01225146
Study of 2.0 mg Ranibizumab in Subjects With Ischemic Central Retinal Vein Occlusion (RAVE2)treatment1terminated
NCT01198327
Extended Follow-up of Patients With Macular Edema Due to Retinal Vein Occlusiontreatment3completed
NCT01012973
Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)treatment3completed
NCT01027481
Ranibizumab in Patients With Branch Retinal Vein Occlusiontreatment4completed
NCT01011374
Impact of Lucentis on Psychological Morbidity in Patients With Retinal Vein Occlusiontreatment1unknown_status
NCT01027650
Safety and Efficacy of AGN208397 in the Treatment of Macular Edema Associated With Retinal Vein Occlusion (RVO)treatment1 / 2completed
NCT00831350
Posterior Vitreous Detachment (PVD) Assessment During Dual Retinal Vein Occlusion (RVO) Lucentis Evaluationstreatment2completed
NCT00732927
Parnaparin vs Aspirin in the Treatment of Retinal Vein Occlusiontreatment3terminated
NCT00517257
Atorvastatin for the Treatment of Retinal Vein Occlusiontreatment3unknown_status
NCT00403039
Intravitreal Ranibizumab Treatment of Central Retinal Vein Occlusion With Macular Edematreatment1completed
NCT00168324
A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusiontreatment3completed
NCT00000131
Central Vein Occlusion Study (CVOS)No drug interventionstreatment3completed
NCT01946399
Ozurdex Implant for Macular Edema After Treatment Failure With Anti-VEGFtreatmentNot Availableterminated
NCT05476926
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology ProductsNot AvailableNot Availablerecruiting
NCT01282411
Anatomic Outcomes Following Ozurdex InjectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01992575
OCT in Retinal Vein OcclusionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01085734
Single Site, Masked, Randomized, Controlled Study to Assess Efficacy of Osurdex as Adjunct to Avastin Compared With Avastin Alone in the Treatment of Patients With Macular Edema Due to Central or Branch Retinal Vein Occlusiontreatment4completed
NCT02867735
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular EdemaNo drug interventionstreatment1completed