Untreated Adult Acute Myeloid Leukemia (DBCOND0028532)

Identifiers

Synonyms
Not Available

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00003190
Combination Chemotherapy With or Without Valspodar in Treating Patients With Previously Untreated Acute Myeloid Leukemiatreatment3completed
NCT00112853
Tipifarnib and Etoposide in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment1completed
NCT00095797
XK469R in Treating Patients With Refractory Hematologic CancerNo drug interventionstreatment1completed
NCT02921061
Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDStreatment1 / 2completed
NCT02583893
Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemiabasic_science2completed
NCT00602771
Tipifarnib and Etoposide in Treating Older Patients With Newly Diagnosed, Previously Untreated Acute Myeloid Leukemiatreatment2completed
NCT02323607
Pacritinib and Chemotherapy in Treating Patients With Acute Myeloid Leukemia and FLT3 Mutationstreatment1completed
NCT01907815
Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Acute Myeloid Leukemiatreatment2terminated
NCT00025415
Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunctiontreatment1completed
NCT01831232
Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromestreatmentNot Availablecompleted
NCT00703300
Decitabine and Bortezomib in Treating Patients With Acute Myeloid Leukemiatreatment1completed
NCT02144675
Choline Magnesium Trisalicylate and Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemiatreatment2completed
NCT01521936
Cholecalciferol in Treating Patients With Acute Myeloid Leukemia Undergoing Intensive Induction ChemotherapyNo drug interventionssupportive_care2terminated
NCT00093418
S0432 Tipifarnib in Treating Older Patients With Acute Myeloid Leukemiatreatment2completed
NCT02121418
Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative NeoplasmtreatmentNot Availablecompleted
NCT00039117
Oblimersen, Cytarabine, and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemiatreatment1completed
NCT00003934
Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemiatreatment3completed
NCT00101296
Tipifarnib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1completed
NCT02044796
Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromestreatment1 / 2completed
NCT00078858
Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplanttreatment1 / 2completed
NCT00014235
Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic MalignanciestreatmentNot Availablecompleted
NCT00313586
Azacitidine With or Without Entinostat in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemiatreatment2completed
NCT01141725
Bendamustine and Idarubicin in Treating Older Patients With Previously Untreated AML or MDStreatment1 / 2completed
NCT00278330
Flavopiridol and Vorinostat in Treating Patients With Relapsed or Refractory Acute Leukemia or Chronic Myelogenous Leukemia or Refractory Anemiatreatment1completed
NCT02381548
Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemiatreatment1terminated
NCT00098826
SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromestreatment1completed
NCT01690065
Nilotinib-Chemotherapy in CML Myeloid BP or Bcr-abl(+) AMLtreatment2unknown_status
NCT00352365
Lenalidomide in Treating Older Patients With Acute Myeloid Leukemiatreatment2completed
NCT00027820
Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancertreatment1 / 2completed
NCT00305773
Vorinostat in Treating Patients With Acute Myeloid Leukemiatreatment2completed
NCT01101880
Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasmtreatment2completed
NCT00445744
Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic SyndrometreatmentNot Availablecompleted
NCT03009240
Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT01798901
AR-42 and Decitabine in Treating Patients With Acute Myeloid Leukemiatreatment1completed
NCT01804101
Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid LeukemiatreatmentNot Availablecompleted
NCT00027872
Tipifarnib in Treating Older Patients With Previously Untreated Acute Myeloid Leukemiatreatment2completed
NCT01349972
Alvocidib, Cytarabine, and Mitoxantrone Hydrochloride or Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2completed
NCT01031368
Clofarabine, Cytarabine, and Filgrastim Followed by Infusion of Non-HLA Matched Ex Vivo Expanded Cord Blood Progenitors in Treating Patients With Acute Myeloid Leukemiatreatment1completed
NCT01801046
Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemiatreatment1terminated
NCT00459212
GTI-2040 in Treating Patients With Relapsed, Refractory, or High-Risk Acute Leukemia, High-Grade Myelodysplastic Syndromes, or Refractory or Blastic Phase Chronic Myelogenous Leukemiatreatment1completed
NCT02122081
Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignanciestreatment1completed
NCT02093403
Decitabine and Selinexor in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1completed
NCT01361464
Tipifarnib in Treating Older Patients With Acute Myeloid Leukemiatreatment2completed
NCT00795002
Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2completed
NCT01307579
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemiasupportive_care3completed
NCT01802333
Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemiatreatment3completed
NCT01876953
Dasatinib, Cytarabine, and Idarubicin in Treating Patients With High-Risk Acute Myeloid Leukemiatreatment1 / 2terminated
NCT00673153
Vorinostat and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemiatreatment2terminated
NCT00008177
Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromestreatment1completed
NCT01869777
Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute LeukemiaNo drug interventionsdiagnosticNot Availablecompleted
NCT01564277
Rasburicase and Allopurinol in Treating Patients With Hematologic Malignanciestreatment2terminated
NCT01044745
Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancertreatment2terminated
NCT00416598
Decitabine as Maintenance Therapy After Standard Therapy in Treating Patients With Previously Untreated Acute Myeloid Leukemiatreatment2completed
NCT00462605
MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemiatreatment2completed
NCT00089011
Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancertreatment2completed
NCT01806571
Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2completed
NCT00079378
Decitabine and Valproic Acid in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphomatreatment1completed
NCT01822015
Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment0completed
NCT01588015
Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell TransplantNo drug interventionssupportive_care1completed
NCT00357032
PXD101 in Treating Patients With Acute Myeloid Leukemiatreatment2completed
NCT01567059
Tosedostat in Combination With Cytarabine or Decitabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment2completed
NCT01633099
Therapeutic Effect and Safety Study of Decitabine in Elderly Acute Myeloid Leukemia Patientstreatment3unknown_status
NCT01130506
Decitabine, Vorinostat, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrometreatment1completed
NCT02581917
Metabolic Changes in Blood Samples From Patients With Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02029417
Omacetaxine Mepesuccinate, Cytarabine, and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2terminated
NCT00085124
Daunorubicin Hydrochloride, Cytarabine and Oblimersen Sodium in Treating Patients With Previously Untreated Acute Myeloid Leukemiatreatment3completed
NCT02105116
AML Therapy With Irradiated Allogeneic CellstreatmentNot Availableterminated
NCT00016016
Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemiatreatment1 / 2completed
NCT01519596
Symptom-Adapted Physical Activity Intervention in Minimizing Physical Function Decline in Older Patients With Acute Myeloid Leukemia Undergoing ChemotherapyNo drug interventionssupportive_careNot Availablecompleted
NCT00006363
Combination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 in Treating Patients With Acute Myeloid Leukemiatreatment3completed
NCT01132586
Lenalidomide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemiatreatment1completed
NCT00096122
Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemiatreatment1 / 2completed
NCT02835222
Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patientstreatment2recruiting
NCT00742625
Bortezomib, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemiatreatment1 / 2completed
NCT00096148
Idarubicin and Cytarabine With or Without Bevacizumab in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2terminated
NCT00387426
Sunitinib in Treating Patients With Idiopathic Myelofibrosistreatment2terminated
NCT02472626
6,8-Bis(Benzylthio)Octanoic Acid, Cytarabine, and Daunorubicin Hydrochloride in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment1 / 2withdrawn
NCT00407966
Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2completed
NCT01273766
Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignanciessupportive_care2completed
NCT00383474
Tipifarnib and Bortezomib in Treating Patients With Acute Leukemia or Chronic Myelogenous Leukemia in Blast Phasetreatment1completed
NCT00049582
Decitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemiatreatment1terminated
NCT01093573
Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemiatreatment1 / 2completed
NCT02634827
Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutationtreatment2terminated
NCT00012376
Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancertreatment1completed
NCT01849276
Metformin+Cytarabine for the Treatment of Relapsed/Refractory AMLtreatment1terminated
NCT00275080
Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemiatreatment1completed
NCT00801489
Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment2recruiting
NCT01839240
Azacitidine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With High-Risk Acute Myeloid Leukemiatreatment1completed
NCT02129101
Azacitidine and Sonidegib or Decitabine in Treating Patients With Myeloid Malignanciestreatment1completed
NCT00492401
Decitabine in Treating Patients With Previously Untreated Acute Myeloid Leukemiatreatment2completed
NCT01555268
Trebananib With or Without Low-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemiatreatment1completed
NCT02159495
Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasmtreatment1active_not_recruiting
NCT02115295
Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemiatreatment2recruiting
NCT01260714
Azacitidine, Mitoxantrone Hydrochloride, and Etoposide in Treating Older Patients With Poor-Prognosis Acute Myeloid Leukemiatreatment1terminated
NCT02096055
Guadecitabine With or Without Idarubicin or Cladribine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemiatreatment2completed
NCT00475150
Cediranib Maleate in Treating Patients With Relapsed, Refractory, or Untreated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment2completed
NCT02666950
WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrometreatment2completed
NCT02085408
Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment3active_not_recruiting
NCT00301938
7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromestreatment1completed
NCT01041443
5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromestreatment1completed