Fluid Loss (DBCOND0062339)

Identifiers

Synonyms

Fluid loss / Fluid loss (observable entity) / Dehydration / Exsiccosis / Dehydration (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Ammonium chloride	Expectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium...	No drug targets
Calcium chloride	An ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate.	Protein S100-A13target
D-glucose	A most commonly occurring isomer of glucose used as a carbohydrate supplementation in case of nutrient deprivation and metabolic disorders, such as hypoglycemia.	Hexokinase-1enzyme Hexokinase-4enzyme Solute carrier family 2, facilitated glucose transporter member 1transporter Solute carrier family 2, facilitated glucose transporter member 2transporter Solute carrier family 2, facilitated glucose transporter member 3transporter Solute carrier family 2, facilitated glucose transporter member 4transporter Solute carrier family 2, facilitated glucose transporter member 5transporter Solute carrier family 2, facilitated glucose transporter member 6transporter Solute carrier family 2, facilitated glucose transporter member 7transporter Solute carrier family 2, facilitated glucose transporter member 8transporter Solute carrier family 2, facilitated glucose transporter member 9transporter Solute carrier family 2, facilitated glucose transporter member 10transporter Solute carrier family 2, facilitated glucose transporter member 11transporter Solute carrier family 2, facilitated glucose transporter member 12transporter Sodium/glucose cotransporter 1transporter Sodium/glucose cotransporter 2transporter Albumincarrier
Dextrose, unspecified form	A form of glucose used for caloric supply and the replenishment of fluid in total parenteral nutrition and other therapies as well as for the treatment of hypoglycemic episodes.	Hexokinase-4enzyme Hexokinase-1enzyme Solute carrier family 2, facilitated glucose transporter member 1transporter Solute carrier family 2, facilitated glucose transporter member 2transporter Solute carrier family 2, facilitated glucose transporter member 3transporter Solute carrier family 2, facilitated glucose transporter member 4transporter Solute carrier family 2, facilitated glucose transporter member 6transporter Solute carrier family 2, facilitated glucose transporter member 7transporter Solute carrier family 2, facilitated glucose transporter member 8transporter Solute carrier family 2, facilitated glucose transporter member 9transporter Solute carrier family 2, facilitated glucose transporter member 10transporter Solute carrier family 2, facilitated glucose transporter member 11transporter Solute carrier family 2, facilitated glucose transporter member 12transporter Sodium/glucose cotransporter 1transporter
Gluconic Acid	An electrolyte supplement used in total parenteral nutrition.	No drug targets
Lactic acid	An emollient and keratolytic used agent in various cosmetic products and used as an additive in various pharmaceutical products for its antibacterial properties.	Bifunctional protein PutAtarget NimA-related proteintarget Monocarboxylate transporter 2transporter Solute carrier organic anion transporter family member 2B1transporter Monocarboxylate transporter 1transporter Monocarboxylate transporter 10transporter Solute carrier organic anion transporter family member 2A1transporter Monocarboxylate transporter 4transporter
Sodium chloride	An ingredient found in a variety of nutritional products as a source of electrolytes and water.	No drug targets

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06101498	Peroperative Fluid Management in Major Gynecological Cancer Surgeries	No drug interventions	health_services_research	Not Available	completed
NCT01788293	Fluid Management Based on Pleth Variability Index (PVI) Monitoring During High-risk Surgery	No drug interventions	supportive_care	Not Available	terminated
NCT05705115	Acetated Ringer´s Solution in Experimental Hypovolemia	No drug interventions	basic_science	4	recruiting
NCT05278013	Utility of 2- Octyl Cyanoacrylate (2-OCA)	No drug interventions	health_services_research	Not Available	enrolling_by_invitation
NCT05070819	Atrial Natriuretic Peptide in Assessing Fluid Status	No drug interventions	diagnostic	Not Available	completed
NCT04598386	The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration	No drug interventions	basic_science	Not Available	completed
NCT05012462	Clinical Evaluation of the CM-1500 During Apheresis Blood Donation	No drug interventions	diagnostic	Not Available	completed
NCT05740644	Clinical Evaluation of the Zynex Monitoring System, Model CM-1600	No drug interventions	diagnostic	Not Available	completed
NCT03133767	Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation	No drug interventions	treatment	4	completed
NCT06097923	Implementation of Fluid Strategies Using Real-time Bioelectrical Analyzer in Surgical Intensive Care Unit (SICU)	No drug interventions	treatment	Not Available	completed
NCT02052284	The Application of Sterile Water to the Skin of Extremely Low Birth Weight (ELBW) Infants	No drug interventions	prevention	Not Available	completed
NCT05463198	Evaluation of Physiological Variables and Detection of Blood Loss Using the Zynex Fluid Monitoring System, Model CM-1600	No drug interventions	diagnostic	Not Available	completed
NCT05968105	Changes in Vessels After Peripheral Block	No drug interventions	Not Available	Not Available	completed
NCT06026475	Role of Goal Directed Fluid Therapy in Enhanced Recovery After Surgery in Gastro-intestinal Oncosurgeries	No drug interventions	treatment	Not Available	completed
NCT05980013	Evaluation of Physiological Variables and Detection of Blood Loss in Healthy Adults With Different Subject Positioning by the CM-1500	No drug interventions	diagnostic	Not Available	completed
NCT05125848	Clinical Evaluation of the CM-1500 During Hemodialysis	No drug interventions	diagnostic	Not Available	completed
NCT03204292	Evaluating the Fluid Balance of Mechanically Ventilated Patients by Ultrasonography	No drug interventions	Not Available	Not Available	completed
NCT03552601	The Effect of Negatively Fluid Balancing Speed for ICU Patients With Acute Respiratory Distress Syndrome	No drug interventions	treatment	Not Available	unknown_status