Keratitis, Ulcerative (DBCOND0145587)

Identifiers

Synonyms
Corneal Ulcers / Corneal Ulcer / Ulcerative keratitis / Unspecified corneal ulcer / Ulcer corneal / Corneal ulceration / Corneal ulcer, unspecified / Corneal ulcer (disorder) / Inflammatory corneal ulcer (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Framycetin
An aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus.
Gramicidin D
A bactericidal antibiotic used in the treatment of dermatological and ophthalmic infections.
Ofloxacin
An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02168790
Safety Study of a Sutureless Amniotic Membran Transplantation to Treat Ocular Surface Disorders (Expanded Access)No drug interventionstreatment0completed
NCT01928693
A Comparison of Three Fluoroquinolone Topical Eyedrops in the Treatment of Infectious Corneal Ulcers.treatment2terminated
NCT02068430
Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking in Eyes With Refractory Corneal Infectiontreatment1completed
NCT02138019
The Application of Fibrin Glue (Tissucol Duo Quick) in External Eye SurgeriesNo drug interventionstreatmentNot Availablecompleted
NCT04484402
Treatment of Patients With Inflammatory-dystrophic Diseases of the Cornea Using Autologous Stem CellsNo drug interventionstreatment1 / 2completed
NCT01104961
Studying the Relationship Between Contact Lens Packaging Solutions and Bacterial Binding to Surface Eye CellsNo drug interventionssupportive_careNot Availablewithdrawn
NCT05313828
Effect of Various Treatment Modalities on Dendritic Vial UlcerNot AvailableNot Availableunknown_status
NCT05255107
Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcerstreatment2 / 3unknown_status
NCT01756456
Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis.treatment1 / 2completed
NCT05891106
AONDA Therapeutic Indication Study INo drug interventionsNot AvailableNot Availablecompleted
NCT04054817
ACRO Biocornea Clinical Trial in TaiwanNo drug interventionstreatmentNot Availablecompleted
NCT05705024
Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cellstreatment2recruiting
NCT00386958
A Clinical Trial of Povidone-Iodine for the Treatment of Bacterial Corneal Ulcerstreatment2completed
NCT00997035
The Mycotic Ulcer Treatment Trial II: A Randomized Trial Comparing Oral Voriconazole vs Placebotreatment3completed
NCT01242839
Randomized Double Blinded Study Evaluating CACICOL20 Efficiency Versus Placebo Corneal Chronic Ulcers HealingNo drug interventionstreatmentNot Availablecompleted
NCT04075669
Multiplex Strip Polymerase Chain Reaction for Diagnosis of Eye Infection Diseases From Corneal Scraping SamplesNo drug interventionsNot AvailableNot Availableunknown_status
NCT01794312
Efficacy and Safety Assessment of T4020 Versus Vehicule in Patients With Chronic Neurotrophic Keratitis or Corneal UlcerNo drug interventionstreatment3completed
NCT02570321
Cross-linking for Corneal Ulcers Treatment TrialNo drug interventionstreatment3completed
NCT00155402
The Application of Fibrin Glue in Ocular Surface Diseasestreatment1withdrawn
NCT02277054
Safety and Effectiveness of Collagen-phosphorylcholine Bioengineered Cornea in Patients Requiring Lamellar KeratoplastyNo drug interventionstreatmentNot Availablecompleted
NCT06411145
Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitistreatment4active_not_recruiting
NCT02284698
Corneal Ulcer Prevention Through Health EducationNo drug interventionsNot AvailableNot Availableunknown_status
NCT04164407
Keratoconus, Corneal Diseases and Transplant RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT05200000
Wharton's Jelly Eye Drops in the Treatment of Chronic KeratitisNo drug interventionstreatment1completed
NCT05172349
Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Trophic UlcersNo drug interventionstreatment2withdrawn
NCT00996736
Mycotic Ulcer Treatment Trial Itreatment3completed
NCT04837534
Improving the Follow up Rate for Pediatric PatientsNo drug interventionshealth_services_researchNot Availablecompleted
NCT05255016
Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Refractory Corneal Ulcerstreatment2 / 3recruiting
NCT01969786
Village Integrated Eye Workers TrialNo drug interventionspreventionNot Availableactive_not_recruiting
NCT02826174
Topical Anesthesia for Closed PKP vs Retrobulbar Anesthesia for Open-sky PKPNo drug interventionstreatmentNot Availableunknown_status
NCT05940376
Topical Insulin in Neurotrophic Keratopathy After Diabetic VitrectomyNot AvailableNot Availablenot_yet_recruiting
NCT01244776
Transplantation of Acellular Corneal Matrix to Treat Corneal UlcerNo drug interventionstreatmentNot Availableunknown_status
NCT02293876
Corneal Lesions in Intensive Care Unit (ICU) Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care CenterNo drug interventionspreventionNot Availablecompleted
NCT02984904
Fusarium Keratitits in Spain 2012 to 2014No drug interventionsNot AvailableNot Availablecompleted
NCT00324168
Steroids for Corneal Ulcers Trialtreatment4completed
NCT00789646
Painless Subconjunctival Antibiotic and Antifungal Injection in Corneal Ulcer PatientsNo drug interventionstreatmentNot Availableterminated
NCT04820010
Topical Insulin - Utility and Results in Neurotrophic Keratopathy in Stages 2 and 3Not AvailableNot Availablecompleted
NCT01560208
The Asia Cornea Society Infectious Keratitis StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02731638
Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcerstreatment3completed
NCT05268718
Au-Ag-Cu2O NG With PTT Anti Drug-resistant Microbial Keratitistreatment0unknown_status