Allergic cough (DBCOND0013588)

Identifiers

Synonyms

Allergic cough (finding)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Ammonium chloride	Expectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium...	No drug targets
Chlorpheniramine	A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.	Histamine H1 receptortarget Cytochrome P450 3A4enzyme Cytochrome P450 2D6enzyme Sodium-dependent serotonin transportertarget Sodium-dependent noradrenaline transportertarget Sodium-dependent dopamine transportertarget Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme Solute carrier family 22 member 2transporter Solute carrier family 22 member 1transporter
Dextromethorphan	An NMDA receptor antagonist used to treat cases of dry cough.	Sigma non-opioid intracellular receptor 1target Neuronal acetylcholine receptor subunit alpha-2target Sodium-dependent serotonin transportertarget Glutamate receptor ionotropic, NMDA 3Atarget Cytochrome P450 2D6enzyme Cytochrome P450 3A4enzyme Cytochrome P450 3A7enzyme Cytochrome P450 2C9enzyme Cytochrome P450 2B6enzyme Cytochrome P450 2C19enzyme Membrane-associated progesterone receptor component 1target Neuronal acetylcholine receptor subunit alpha-3target Neuronal acetylcholine receptor subunit alpha-4target Neuronal acetylcholine receptor subunit beta-4target Neuronal acetylcholine receptor subunit beta-2target Neuronal acetylcholine receptor subunit alpha-7target Mu-type opioid receptortarget Delta-type opioid receptortarget Kappa-type opioid receptortarget NADPH oxidasetarget Sodium-dependent noradrenaline transportertarget UDP-glucuronosyltransferase 2B4enzyme UDP-glucuronosyltransferase 2B7enzyme UDP-glucuronosyltransferase 2B15enzyme UDP-glucuronosyltransferase 2B17enzyme Aromatasetarget
Diphenhydramine	A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.	Histamine H1 receptortarget Cytochrome P450 2D6enzyme Cytochrome P450 2C9enzyme Cytochrome P450 2C19enzyme Solute carrier family 22 member 2transporter Organic cation/carnitine transporter 2transporter Prostaglandin G/H synthase 1enzyme Muscarinic acetylcholine receptor M2target Histamine N-methyltransferasetarget
Ipecac	An emetic agent used to induce vomiting in poisoning.	Cytochrome P450 2D6enzyme Cytochrome P450 3A4enzyme
Potassium guaiacolsulfonate	A mucolytic and expectorant indicated to relieve a productive cough.	No drug targets
Sodium citrate	An ingredient used for the anticoagulation of whole blood as part of automated apheresis procedures.	Mitochondrial 2-oxodicarboxylate carriertransporter Solute carrier family 13 member 2transporter Na(+)/citrate cotransportertransporter Tricarboxylate transport protein, mitochondrialtransporter Carbonic anhydrase 4target

Clinical Trials

Not Available