| Dornase alfa | A synthetic form of human deoxyribonuclease I used to break down extracellular DNA in the lungs, a major source of mucous viscosity in cystic fibrosis. |
| Codeine | An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. |
| Mannitol | A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. |
| Benzonatate | A non-narcotic oral antitussive drug used to suppress coughing. |
| Guaifenesin | An expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses. |
| Hydrocodone | An opioid agonist used as an analgesic and antitussive agent. |
| Stepronin | Strepronin is a mucolytic (expectorant) drug. |
| Ethylmorphine | Ethylmorphine is an analgesic used for pain relief. |
| Acetyldihydrocodeine | Not Available |
| Eucalyptol | A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. |
| Carbocisteine | Used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis. |
| Oxeladin | Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. |
| Clofedanol | An antitussive used for the symptomatic relief of acute cough caused by minor throat and bronchial irritation. |
| Erdosteine | Fro the treatment of chronic bronchitis in adults. |
| Acetylcysteine | A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. |
| Noscapine | Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma. |
| Tyloxapol | Tyloxapol is an inhaled surfactant that assists in removing and liquefying and removing bronchopulmonary secretions with mucus and pus. Tyloxapol is administered either through nebulized solution or a stream of... |
| Ambroxol | Ambroxol is indicated for secretolytic therapy in bronchoplmonary diseaes with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing. |
| Letosteine | Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions. |
| Isoaminile | Isoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties. |
| Eprazinone | Eprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms. |
| Cloperastine | Cloperastine is a cough suppressant that acts on the central nervous system. |
| Clobutinol | Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in... |
| Bromhexine | Bromhexine is an expectorant/mucolytic agent. Bromhexine is not available in the United States. It is marketed under the trade name Bisolvon(R) in Germany, England, Belgium, France, Italy, Netherlands, Norway, Sweden,... |
| Pholcodine | Pholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough."... |
| Pentoxyverine | A medication used to suppress a cough in the common cold, flu, bronchitis, and sinusitis. |
| Normethadone | An opioid antitussive used to treat a cough associated with inflamed mucosa. |
| Levodropropizine | Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine). |
| Hedera helix leaf extract | An extract from Hedera helix leaf used in allergy testing. |
| Oxolamine | Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant . It is listed as a prescription drug in New Zealand legislation .... |
| Piperidione | Piperidione was cough medicine marketed by Roche under the trade name Sedulon. |
| Neltenexine | Neltenexine is an elastase inhibitor. It may be useful for preventing pulmonary emphysema. |
| Wood creosote | Not Annotated |
| Ipecac | An emetic agent used to induce vomiting in poisoning. |
| Benproperine | Not Annotated |
| Sobrerol | Not Annotated |
| Levoverbenone | Not Annotated |
| Prenoxdiazine | Not Annotated |
| Droxypropine | Not Annotated |
| Nepinalone | Not Annotated |
| Thebacon | Not Annotated |
| Antimony pentasulfide | Not Annotated |
| Tipepidine | Not Annotated |
| Althea root | Not Annotated |
| Morclofone | Not Annotated |
| Zipeprol | Not Annotated |
| Bibenzonium | Not Annotated |
| Butamirate | Not Annotated |
| Domiodol | Not Annotated |
| Dropropizine | Not Annotated |
| Dimethoxanate | Not Annotated |
| Dibunate | Not Annotated |
| Dimemorfan | Not Annotated |
| Meprotixol | Not Annotated |
| Fedrilate | Not Annotated |
| Dextromethorphan | An NMDA receptor antagonist used to treat cases of dry cough. |
| Potassium Iodide | An oral antithyroid agent used for the prevention of radioactive iodine uptake into the thyroid gland during a nuclear radiation emergency. |
| Pipazethate | For the treatment of cough. |
| Coenzyme M | A uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract. |
| Polygala senega root | Not Annotated |