B-cell Acute Lymphoblastic Leukemia (DBCOND0034372)

Identifiers

Synonyms
B-cell Acute Lymphoblastic Leukemia( B-ALL ) / Acute Lymphoblastic Leukemia,B-Cell / Acute B-cell Lymphoblastic Leukemia / Acute B Lymphoblastic Leukemia / B Cell ALL / B-Cell ALL / B-cell Acute Lymphoblastic Leukemia (B-ALL) / B-All / B-Cell Acute Lymphoblastic Leukaemia / Acute B-Cell Lymphoblastic Leukaemia / B ALL / B-cell acute lymphoblastic leukemia / B-cell type acute leukemia NOS / B-cell type acute leukaemia NOS / B-cell type acute leukemia / B-cell type acute leukaemia / Precursor B-cell lymphoblastic leukemia (morphologic abnormality) / B-cell acute lymphoblastic leukemia (disorder) / Burkitt Leukemia / Burkitt's leukaemia / Burkitt's leukemia / Burkitt cell leukemia (morphologic abnormality) / Mature B-cell leukemia Burkitt-type not having achieved remission / Mature B-cell leukemia Burkitt-type

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06514768
JY231(JY231) Injection for the Treatment of B-cell Acute Lymphoblastic Leukemia(B-ALL)No drug interventionstreatment0recruiting
NCT06346912
CD19-BAFF CAR-T Cells Therapy for Patients With Relapsed / Refractory B-cell ALL and B-cell NHLNo drug interventionstreatment0recruiting
NCT06339775
Blinatumomab for Relapsed Acute B Lymphoblastic Leukemia After Transplantationtreatment4recruiting
NCT05379569
Comparative Study of BFC and BuCy Conditioning Regimen for Allo-PBSCT in Acute B-cell ALLtreatment4recruiting
NCT04148430
A Study of Anakinra to Prevent or Treat Severe Side Effects for Patients Receiving CAR-T Cell Therapytreatment2active_not_recruiting
NCT02050347
Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO)No drug interventionstreatment1active_not_recruiting
NCT03914625
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemiatreatment3active_not_recruiting
NCT04544592
UCD19 CarT in Treatment of Pediatric B-ALL and B-NHLNo drug interventionstreatment1 / 2recruiting
NCT06208735
CLIC-2201 for the Treatment of Relapsed/Refractory B Cell MalignanciesNo drug interventionstreatment1not_yet_recruiting
NCT06317662
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemiatreatment2not_yet_recruiting
NCT06533579
Gene Therapy for B-Cell Acute Lymphoblastic LeukemiaNo drug interventionstreatment1 / 2recruiting
NCT06559189
CD19x22 Chimeric Antigen Receptor T-cell Therapy (CAR T) in Pediatric B-ALLNo drug interventionstreatment1recruiting
NCT04094311
Study of Out of Specification for Tisagenlecleuceltreatment3recruiting
NCT06124157
A Study Comparing the Combination of Dasatinib and Chemotherapy Treatment With or Without Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or Philadelphia Chromosome-Like (Ph-Like) ABL-Class B-Cell Acute Lymphoblastic Leukemia (B-ALL)treatment3not_yet_recruiting
NCT06580301
Study of YK012 in B-cell Acute Lymphoblastic LeukemiaNo drug interventionstreatment1 / 2recruiting
NCT02883049
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutationstreatment3active_not_recruiting
NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)treatment1 / 2recruiting
NCT05557110
Reduced-dose Chemotherapy Followed by Blinatumomab in Induction Therapy of Newly Diagnosed Non-elderly Ph-B-ALLtreatment2completed
NCT05602194
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphomasupportive_care3recruiting
NCT05667506
A Study of CNCT19 Treatment in Children and Adolescent r/r ALL Patients(Pediatric)treatment1 / 2recruiting
NCT06608732
Combination of Inaticabtagene Autoleucel With Autologous Hematopoietic Stem Cell Transplantation for Adolescents or Adults With MRD-Positive B-Cell Acute Lymphoblastic Leukemia in Initial Complete Remission.treatment2recruiting
NCT06450067
Inaticabtagene Autoleucel Injection Treatment for Adult Relapsed or Refractory Acute Lymphocytic LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02877303
Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemiatreatment2recruiting
NCT06343090
Clinical Trial of CD19 and CD22 CAR Sequential Therapy Versus Single CD19 CAR Bridging to HSCT for r/r B-ALL PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT04872790
Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemiatreatment1recruiting
NCT04556084
Blinatumomab Bridging Therapytreatment2recruiting
NCT05639179
Novel Anti-CD19 Universal CAR-T Cells for r/r CD19+ B-ALLNo drug interventionstreatment1 / 2recruiting
NCT05460533
A Second Infusion (Early Reinfusion) of Tisagenlecleucel in Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia(B-ALL)treatment2recruiting
NCT03233854
CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignanciestreatment1active_not_recruiting
NCT03281551
Efficacy and Safety of PZ01 Treatment in Patients With r/r CD19+ B-cell Acute Lymphoblastic Leukemia/B Cell LymphomaNo drug interventionstreatment1unknown_status
NCT05470777
CD22/CD19 CAR-T and Auto-HSCT Sandwich Strategy as Consolidation Therapy for B-ALLNo drug interventionstreatment1 / 2recruiting
NCT05379647
Natural Killer (NK) Cell Therapy for B-Cell Malignanciestreatment1recruiting
NCT05016947
Venetoclax Plus Inotuzumab for B-ALLtreatment1recruiting
NCT06389305
CIK Cell Therapy for Relapsed or Refractory Acute B-Lymphoblastic Leukemia: Prognostic Impact on Patients With Early CAR-T Cell DysfunctionNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04150497
Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)treatment1 / 2recruiting
NCT03441061
Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Diseasetreatment2recruiting
NCT03150693
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemiatreatment3suspended
NCT05157971
Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemiatreatment1active_not_recruiting
NCT05020678
NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell CancersNo drug interventionstreatment1recruiting
NCT01207388
Confirmatory Phase II Study of Blinatumomab (MT103) in Patients With Minimal Residual Disease of B-precursor Acute Lymphoblastic Leukemia (ALL)treatment2completed
NCT04746209
Blinatumomab After TCR Alpha Beta/CD19 Depleted HCTtreatment2recruiting
NCT06393985
Decitabine, Venetoclax and Blinatumomab for Maintenance Following HSCT in Patients With Ph-Negative B-ALLtreatment2not_yet_recruiting
NCT06056752
QH103 Cell Injection for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemiatreatment1recruiting
NCT02746952
Dose Escalation Study of UCART19 in Adult Patients With Relapsed / Refractory B-cell Acute Lymphoblastic LeukaemiaNo drug interventionstreatment1completed
NCT03666000
Dose-escalation, Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Patients With r/r NHL and r/r B-cell ALLtreatment1recruiting
NCT06034275
Study of VIP943 in Subjects With Advanced CD123+ Hematologic MalignanciesNo drug interventionstreatment1recruiting
NCT05674175
Co-administration of CART22-65s and huCART19 for B-ALLNo drug interventionstreatment1 / 2recruiting
NCT04129099
A Study of GC022F CAR-T Cell Immunotherapy for Relapsed or Refractory B- ALLNo drug interventionstreatment0unknown_status
NCT06078306
CD19CD22 CAR-T Therapy in Patients With High-Risk B Acute Lymphoblastic Leukemia (B-ALL).treatment2recruiting
NCT03638206
Autologous CAR-T/TCR-T Cell Immunotherapy for MalignanciesNo drug interventionstreatment1 / 2unknown_status
NCT02435849
Study of Efficacy and Safety of CTL019 in Pediatric ALL Patientstreatment2completed
NCT03825718
A Study of GC007F CAR-T Cell Immunotherapy for Relapsed or Refractory B- ALLNo drug interventionstreatment0completed
NCT05648019
CD19-Directed Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory B-Lineage Leukaemia / Lymphoma - A Feasibility ProtocolNo drug interventionstreatment2recruiting
NCT05082519
Caloric Restriction and Activity to Reduce Chemoresistance in B-ALLNo drug interventionssupportive_care2recruiting
NCT04191941
Treatment of Hematological Malignancy With Novel CAR-T Cells.No drug interventionstreatment0unknown_status
NCT03856216
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantationtreatment2recruiting
NCT03000335
Evaluation of ProALL miRs in Blood Specimen for Prediction of ALL Relapse RiskNo drug interventionsNot AvailableNot Availableunknown_status
NCT03488225
Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemiatreatment2terminated
NCT06027957
CD19 CAR T-Cell Therapy for R/R Non-Hodgkin Lymphoma and Acute Lymphoblastic LeukemiaNo drug interventionstreatment1recruiting
NCT02538926
Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride With Asparaginase in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphomatreatment2withdrawn
NCT04289220
Anti-CD19 CAR in PiggyBac Transposon-Engineered T Cells for Relapsed/Refractory B-cell Lymphoma or B-cell Acute Lymphoblastic LeukemiaNo drug interventionstreatment1unknown_status
NCT03671460
CD19 CAR-T Cells for Patients With Relapse and Refractory CD19+ B-ALL.No drug interventionstreatment1unknown_status
NCT05310591
Combination of an Anti-PD1 Antibody With Tisagenlecleucel Reinfusion in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia After Loss of Persistencetreatment1 / 2recruiting
NCT04595162
A Study of GC019F CAR-T Cell Immunotherapy for Relapsed or Refractory B- ALLNo drug interventionstreatment1not_yet_recruiting
NCT05130489
CAR T Cell Therapy Related Cardiovascular OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT03982992
Allogeneic Donor Lymphocyte Infusions Combined With Blinatumomabtreatment2withdrawn
NCT05303792
Testing the Combination of Inotuzumab Ozogamicin and Lower Dose Chemotherapy Compared to Usual Chemotherapy for Adults With B-Cell Acute Lymphoblastic Leukemia or B-Cell Lymphoblastic Lymphomatreatment2recruiting
NCT03504644
Venetoclax and Vincristine Liposomal in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemiatreatment1 / 2recruiting
NCT05571540
Anti-CD19 Universal CAR-T Cells for r/r CD19+ B-ALLNo drug interventionstreatment1 / 2withdrawn
NCT02968472
A Phase I Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell LeukemiaNo drug interventionstreatment1unknown_status
NCT03574168
CD19-CAR-T Cells in Patients With R/R B-ALLNo drug interventionstreatment1unknown_status
NCT03876769
Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patientstreatment2active_not_recruiting
NCT06581081
Bridging Allogeneic Hematopoietic Stem Cell Transplantation or Not After CD19 CAR - T (S1904) Cell Therapy for r/r B-cell Acute Lymphoblastic Leukemia, a Prospective, Open, Multicenter, Randomized, Control StudyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04977895
Monitoring Minimal Residual Disease(MRD)in Pediatric B-acute Lymphoblastic LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT06507514
Blinatumomab and Auto-HSCT Sandwich Strategy as Consolidation Therapy for B-ALLtreatment1recruiting
NCT06326008
Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical TrialNo drug interventionstreatment1not_yet_recruiting
NCT05333302
Pilot CAR-T Cells Therapy for Children/Young Adults With CD19+ R/R Leukemia/Lymphomatreatment1recruiting
NCT01974479
Pilot Study of Redirected Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemiatreatment1suspended
NCT02924753
The Safety and Efficacy of CART-19 Cells in B-cell Acute Lymphoblastic Leukemia (B-ALL).treatment1unknown_status
NCT03007147
Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemiatreatment3active_not_recruiting
NCT06220097
Mitoxantrone Hydrochloride Liposome Injection-containing Bridging Regimen and CD19-targeting CAR-T Therapiestreatment2recruiting
NCT03509961
The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALLNo drug interventionstreatment2recruiting
NCT04747093
Induced-T Cell Like NK Cells for B Cell MalignanciesNo drug interventionstreatment1 / 2unknown_status
NCT06081478
CD19/CD22 Bispecific CAR-T Cell Therapy for Relapsed/Refractory B-cell Lymphoma or Acute Lymphoblastic LeukemiaNo drug interventionstreatment2recruiting
NCT05210907
Clinical Study of Hospital-manufactured CD19 CAR-T in Children and Adolescents With Acute Lymphoblastic LeukemiaNo drug interventionstreatment1recruiting
NCT06009107
A Study of HY004 Treatment in Adult Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r B-ALL)treatment1 / 2not_yet_recruiting
NCT02618109
Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic LeukemiaNo drug interventionsother4terminated
NCT05281809
Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic LeukemiaNo drug interventionstreatment2recruiting
NCT03467256
CD19 T-CAR for Treatment of Children and Young Adults With r/r B-ALLtreatment1 / 2active_not_recruiting
NCT03959085
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLytreatment3recruiting
NCT04156659
Study of Tisagenlecleucel in Chinese Pediatric and Young Adult Subjects With Relapsed or Refractory B-cell ALLtreatment2withdrawn
NCT04557436
TT52CAR19 Therapy for B-cell Acute Lymphoblastic Leukaemia (B-ALL)No drug interventionsother1completed
NCT03595917
ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CMLtreatment1recruiting
NCT04448834
Blincyto Amgen Acrotech BioPharma PH2 Blincyto Marqibo R/R Philadelphi CD19+ ALLtreatment2withdrawn
NCT02767934
Pembrolizumab in Treating Minimal Residual Disease in Patients With Acute Lymphoblastic Leukemiatreatment2terminated
NCT04534634
Study of IFN-α Combined With CAR-T Cell Therapy in Relapsed and Refractory Acute Lymphoblastic Leukemia(R/R-ALL)No drug interventionstreatment2recruiting
NCT02146924
Cellular Immunotherapy in Treating Patients With High-Risk Acute Lymphoblastic LeukemiaNo drug interventionstreatment1active_not_recruiting
NCT02228096
Study of Efficacy and Safety of CTL019 in Pediatric ALL Patientstreatment2completed
NCT02828358
Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangementtreatment2active_not_recruiting
NCT04844086
RPM CD19-mbIL15-CAR-T Cells in Patient With Advanced Lymphoid MalignanciesNo drug interventionstreatment1terminated
NCT04264039
Anti-CD19 U-CAR-T Cell Therapy for B Cell Hematologic Malignanciestreatment0unknown_status
NCT02484430
Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemiatreatment2active_not_recruiting
NCT05613348
CD19 CAR T-cell Target Relapsed/Refractory Acute B Cell Leukemia/LymphomaNo drug interventionstreatment1 / 2withdrawn
NCT05747157
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10- 19) in the Treatment of r/r B-ALL Clinical ResearchNo drug interventionstreatment0recruiting
NCT03962465
Phase I Study of Inotuzumab With Augmented BFM Re-Induction for Patients With Relapsed/Refractory B-cell ALLtreatment1active_not_recruiting
NCT03825731
A Study of GC022 CAR-T Cell Immunotherapy for Relapsed or Refractory B- ALLNo drug interventionstreatment0unknown_status
NCT05262673
NGS-MRD Assessment of Combination Immunotherapies Targeting B-ALLNo drug interventionstreatment1recruiting
NCT05707273
CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remissiontreatment1recruiting
NCT02167360
Study of Efficacy and Safety of CTL019 in Adult ALL Patientstreatment2withdrawn
NCT03854994
CD19 CAR-T Cell Therapy for Relapsed/Refractory B-cell Lymphoma and B-cell Acute Lymphoblastic Leukemiatreatment1unknown_status
NCT06080191
Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALLNo drug interventionstreatment1recruiting
NCT05651191
To Evaluate the Safety and Efficacy of Human CD19 Targeted DASH CAR-T Cells Injection for Subjects With R/R B-ALLNo drug interventionstreatment0recruiting
NCT00289562
Forodesine Hydrochloride (BCX-1777) for B-Cell Acute Lymphoblastic Leukemiatreatment1 / 2completed
NCT06559644
Hema-NeoTIL01 Cell Infusion Therapy in Relapsed/Refractory Acute LeukemiaNo drug interventionstreatment0not_yet_recruiting
NCT03241940
Phase I Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignanciestreatment1recruiting
NCT02730312
PH 1 Study to Evaluate Safety and Tolerability of XmAb14045 in Patients With CD123-expressing Hematologic Malignanciestreatment1completed
NCT04184414
The Clinical Application of Chimeric Antigen Receptor T Cells in the Treatment of CD19 Positive Recurrent Refractory B Cell-derived Hematological MalignanciesNo drug interventionstreatment0unknown_status
NCT02458014
Blinatumomab in Treating Patients With B-cell Acute Lymphoblastic Leukemia With Minimal Residual Diseasetreatment2active_not_recruiting
NCT02143414
Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemiatreatment2active_not_recruiting
NCT03289455
CD19 /22 CAR T Cells (AUTO3) for the Treatment of B Cell Acute Lymphoblastic Leukemia (ALL)treatment1 / 2completed
NCT05559450
Blinatumomab as a Bridge to Allo-HSCT in HR BCP-ALLtreatment2recruiting
NCT01406756
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemiatreatment3recruiting
NCT05397496
Study of PIT565 in Relapsed and/or Refractory B-cell MalignanciesNo drug interventionstreatment1recruiting
NCT06137118
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemiatreatment1 / 2recruiting
NCT05513612
Novel CAR-T Cell Therapy in the Treatment of Hematopoietic and Lymphoid Malignanciestreatment1withdrawn
NCT04166838
The Clinical Study of CD19 UCAR-T Cells in Patients With B-cell Acute Lymphoblastic Leukemia (B-ALL)No drug interventionstreatment0unknown_status
NCT05480449
Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)No drug interventionstreatment1 / 2recruiting
NCT01866839
Preventing Stem Cell Transplant Complications With a Blood Separator MachineNo drug interventionstreatment1 / 2completed
NCT04437420
Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800, an Inhibitor of the Heat Shock Protein HSP90No drug interventionsNot AvailableNot Availableunknown_status
NCT04512716
Iomab-ACT: a Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients with Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell LymphomaNo drug interventionstreatment0recruiting
NCT05621291
A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...No drug interventionsdiagnosticNot Availablerecruiting
NCT06579469
Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell TherapyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03448393
CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignanciestreatment1recruiting
NCT05442515
CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignanciestreatment1 / 2recruiting
NCT04088890
Autologous CD22 CAR T Cells in Adults w/ Recurrent or Refractory B Cell Malignanciestreatment1active_not_recruiting
NCT04792593
Senl-h19 CAR-T Cell Injection in the Treatment of Patients With Relapsed or Refractory Acute Lymphoblastic LeukemiaNo drug interventionstreatmentNot Availableunknown_status
NCT03751709
Blinatumomab Plus HLA-Mismatched Cellular Therapy for Relapsed/Refractory CD19+ ALLtreatment1active_not_recruiting
NCT01209286
Study of the BiTE® Blinatumomab (MT103) in Adult Patients With Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia (ALL)treatment2completed
NCT01290120
Chemotherapy Plus Rituximab Combination for Adult Lymphoblastic Leukemia (B-ALL) and Burkitt's Non-Hodgkin Lymphomatreatment2completed
NCT02315612
Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell MalignanciesNo drug interventionstreatment1active_not_recruiting
NCT02328014
Acalabrutinib (ACP-196) in Combination With ACP-319, for Treatment of B-Cell Malignanciestreatment1 / 2active_not_recruiting
NCT05350787
Evaluate the Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With R/R B-ALLNo drug interventionstreatment1unknown_status
NCT04546893
Safety and Efficacy Study of SL1904B CAR-T Cells for Relapsed or Refractory B-Cell Acute Lymphocyte LeukemiaNo drug interventionstreatmentNot Availableunknown_status
NCT04318678
CD123-Directed Autologous T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)treatment1active_not_recruiting
NCT05350852
Evaluate the Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With MRD+ B-ALLNo drug interventionstreatment1unknown_status
NCT04546906
Safety and Efficacy Study of CD22 CAR-T Cells for Relapsed or Refractory Acute Lymphoblastic LeukemiaNo drug interventionstreatmentNot Availableunknown_status
NCT04781634
a Clinical Research of CD19 and CD22 Targeted Prime CAR-T Cell in Relapsed/Refractory B-ALLtreatment1 / 2recruiting
NCT06504186
The Use of Blinatumomab in Patients With NGS-MRD Relapsed B-ALL After Autologous/Allogeneic TransplantationpreventionNot Availablenot_yet_recruiting
NCT04499573
Bispecific CD19/CD22 CAR-T for Treatment of Children and Young Adults With r/r B-ALLtreatment1 / 2active_not_recruiting
NCT03559439
CD19-targeting CAR T Cells in Relapsed or Refractory CD19 Positive B-cell MalignanciesNo drug interventionstreatment1unknown_status
NCT03156790
PK, PD, Safety and Immunogenicity of Spectrila in Adults With Acute B-cell Lymphoblastic Leukaemiatreatment2recruiting
NCT04723901
Dual Target CAR-T Cells in B-cell Acute Lymphoblastic LeukemiaNo drug interventionstreatment1 / 2unknown_status
NCT01219816
Multi-centric Studytreatment2completed