Displaying drugs 376 - 400 of 408 in total
| Name | Weight | Structure | Desription | Categories |
|---|---|---|---|---|
| Teplizumab | 150000.0 C6462H9938N1738O2022S46 |  | A CD3-directed monoclonal antibody indicated to delay the onset of Stage 3 type 1 diabetes in patients with Stage 2 type 1 diabetes. | Alimentary Tract and Metabolism / Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antibodies, Monoclonal, Humanized / Blood Proteins / CD3-directed Antibody / CD3-directed Antibody Interactions / Drugs Used in Diabetes / Globulins / Immunoglobulins / Immunoproteins / Proteins / Serum Globulins |
| Sarilumab | 150000.0 C6388H9918N1718O1998S44 |  | A monoclonal antibody used to treat moderate to severe rheumatoid arthritis who have responded poorly or are intolerant of other DMARDs. | Interleukin Inhibitors |
| Lecanemab | 150000.0 C6544H10088N1744O2032S46 |  | An amyloid beta-targeting antibody used to treat Alzheimer’s Disease in patients with mild cognitive impairment or mild dementia with a known amyloid beta pathology. | Alzheimer Disease / Alzheimer Disease, drug therapy / Amino Acids, Peptides, and Proteins / Amyloid Beta-directed Antibodies / Anti-Dementia Drugs / Antibodies / Antibodies, Monoclonal / Blood Proteins / Globulins / Immunoglobulins / Immunoproteins / Nervous System / Proteins / Psychoanaleptics / Serum Globulins |
| Tafasitamab | 150000.0 | | A CD19-directed cytolytic monoclonal antibody used in the treatment of B-cell malignancies. | Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antibodies, Monoclonal, Humanized / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Blood Proteins / Cancer immunotherapy / Globulins / Immunoglobulins / Immunoproteins / Immunotherapy / Lymphoma, B-Cell / MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES / Proteins / Serum Globulins |
| Mirvetuximab soravtansine | 150000.0 | | A folate receptor alpha-directed antibody and microtubule inhibitor conjugate used to treat folate receptor alpha positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer. | Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antibody-drug Conjugates / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Blood Proteins / Cytochrome P-450 CYP3A Substrates / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 Substrates / Globulins / Immunoconjugates / Immunoglobulins / Immunologic Factors / Immunoproteins / Lactams, Macrocyclic / Lactones / Microtubule Inhibition / MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES / P-glycoprotein substrates / Proteins / Serum Globulins |
| Toripalimab | 150000.0 | | A PD-1 blocking monoclonal antibody used for the treatment of metastatic and recurrent nasopharyngeal carcinomas. | PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors |
| Polatuzumab vedotin | 150000.0 C6670H10317N1745O2087S40 | | A CD79b antibody conjugate indicated to treat different types of large B-cell lymphoma. | Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antibodies, Monoclonal, Humanized / Antibody-drug Conjugates / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Blood Proteins / Cancer immunotherapy / CD79b-directed Antibody–Drug Conjugates / Cytochrome P-450 CYP3A Substrates / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 CYP3A5 Substrates / Cytochrome P-450 Substrates / Globulins / Immunoglobulins / Immunologic Factors / Immunoproteins / Immunotherapy / MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES / Noxae / P-glycoprotein substrates / Proteins / Serum Globulins / Toxic Actions |
| DaxibotulinumtoxinA | 150000.0 | | A botulinum toxin used to treat glabellar lines and cervical dystonia in adults. | Acetylcholine Release Inhibitors / Botulinum Toxins / Botulinum Toxins, Type A / Central Nervous System Depressants / Muscle Relaxants / Muscle Relaxants, Peripherally Acting Agents / Musculo-Skeletal System / Neuromuscular Agents / Neuromuscular Blocking Agents |
| Brentuximab vedotin | 150500.0 C6476H9930N1690O2030S40 |  | A CD30-directed antibody-drug conjugate used to treat various types of lymphoma. | Antibodies, Monoclonal |
| Catumaxomab | 150511.0 |  | For use in the management of malignant ascites tumours via intraperitoneal infusion where standard therapy is not available or feasible [FDA Label]. | Gastrointestinal Agents |
| Botulinum toxin type B | 150804.0 |  | A purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea. | Acetylcholine Release Inhibitors / Anti-Dyskinesia Agents / Neurotoxins |
| Secukinumab | 151000.0 C6584H10134N1754O2042S44 |  | An immunomodulating agent and interleukin antagonist used to manage plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, along with other joint inflammatory disorders. | Interleukin Inhibitors |
| Loncastuximab tesirine | 151000.0 | | An antibody-drug conjugate used for the treatment of relapsed and refractory B-cell lymphomas. | Antineoplastic Agents, Immunological |
| Gemtuzumab ozogamicin | 151500.0 |  | A monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia. | Antibodies, Monoclonal |
| Enfortumab vedotin | 152000.0 | | An antibody-drug conjugate comprised of a fully human monoclonal antibody and microtubule-disrupting chemotherapeutic agent used in the treatment of advanced or metastatic urothelial cancer. | Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antibodies, Monoclonal, Humanized / Antibody-drug Conjugates / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Blood Proteins / Cancer immunotherapy / Cytochrome P-450 CYP3A Substrates / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 Substrates / Globulins / Immunoglobulins / Immunoproteins / Immunotherapy / Microtubule Inhibitors / MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES / Nectin-4-directed Antibodies / P-glycoprotein substrates / Proteins / Serum Globulins |
| Cilgavimab | 152000.0 C6626H10218N1750O2078S44 | | An extended half-life recombinant monoclonal IgG1κ antibody directed against the SARS-CoV-2 S protein for COVID-19 prophylaxis in individuals unable to undergo COVID-19 immunization. | Antiviral monoclonal antibodies |
| Tisotumab vedotin | 153000.0 | | A tissue factor-directed antibody drug conjugate that is used to treat adults with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy. | Antineoplastic Agents, Immunological |
| Olaratumab | 154000.0 C6554H10076N1736O2048S40 | | A platelet-derived growth factor receptor alpha blocking antibody used with doxorubicin to treat patients with certain types of soft tissue sarcoma (STS). | Antibodies, Monoclonal |
| Emapalumab | 154400.0 C6430H9898N1718O2038S46 | | An interferon gamma blocking antibody used to treat primary hemophagocytic lymphohistiocytosis. | Selective Immunosuppressants |
| Turoctocog alfa | 166000.0 C7480H11379N1999O2194S68 |  | An antihemorrhagic agent used for the treatment and prophylaxis of bleeding in patients of all ages with haemophilia A (congenital factor VIII deficiency). | Recombinant Proteins |
| Simoctocog alfa | 170000.0 | | An antihemorrhagic agent used for the treatment and prophylaxis of bleeding in patients of all ages with haemophilia A (congenital factor VIII deficiency). | Amino Acids, Peptides, and Proteins / Carbohydrates / Glycoconjugates / Proteins |
| Susoctocog alfa | 170000.0 | | A recombinant Factor VIII used to treat and prevent bleeding in hemophilia A. | Blood Coagulation Factors |
| Moroctocog alfa | 173000.0 | | A recombinant Factor VIII used to treat hemophilia A to control bleeding. | Recombinant Proteins |
| Asfotase alfa | 180000.0 C7108H11008N1968O2206S56 |  | An enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP). | Enzyme Replacement Therapy / Enzymes / Tissue-nonspecific Alkaline Phosphatase |
| Glofitamab | 194000.0 | | A bispecific monoclonal antibody directed against CD20 and CD3 which is used for the treatment of relapsed or refractory diffuse large B-cell lymphoma. | Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Bispecific Monoclonal Antibodies / Blood Proteins / Globulins / Immunoglobulins / Immunoproteins / MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES / Proteins / Serum Globulins |
Displaying drugs 376 - 400 of 408 in total