Name
Imides
Accession Number
DBCAT000725
Description

Organic compounds containing two acyl groups bound to NITROGEN.

Drugs
DrugDrug Description
LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
Pantothenic acidA vitamin B5 found in various nutritional supplements.
PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
EthosuximideAn anticonvulsant used to treat petit mal seizures.
PhensuximideFor the treatment of epilepsy.
1-Ethyl-Pyrrolidine-2,5-DioneNot Available
Bisindolylmaleimide VIIINot Available
N-EthylmaleimideA sulfhydryl reagent that is widely used in experimental biochemical studies. [PubChem]
Bisindolylmaleimide INot Available
Bis(N-maleimidomethyl)etherNot Available
MethsuximideA succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures.
DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
PanthenolAn ingredient used in skin, hair care, and nutritional products but is not an approved medication.
RuboxistaurinRuboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus.
LY-2090314Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
CC-220CC-220 has been used in trials studying the treatment of Systemic Lupus Erythematosus.
SuccinimideNot Annotated
Hopantenic acidHopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal...
CEP-9722CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
AlbuvirtideAlbuvirtide is under investigation in clinical trial NCT03719664 (Albuvirtide and 3BNC117 as Long-Acting Maintenance Therapy in Virologically Suppressed Subjects).
Drugs & Drug Targets
DrugTargetType
LenalidomideProstaglandin G/H synthase 2target
LenalidomideTumor necrosis factor ligand superfamily member 11target
LenalidomideCadherin-5target
LenalidomideProtein cereblontarget
LenalidomideP-glycoprotein 1transporter
Pantothenic acidPantothenate kinasetarget
PomalidomideCytochrome P450 1A2enzyme
PomalidomideCytochrome P450 3A4enzyme
PomalidomideP-glycoprotein 1transporter
PomalidomideProtein cereblontarget
PomalidomideTumor necrosis factortarget
PomalidomideProstaglandin G/H synthase 2target
ChlorthalidoneSolute carrier family 12 member 1target
ChlorthalidoneSerum albumincarrier
ChlorthalidoneCarbonic anhydrase 1target
EthosuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
EthosuximideCytochrome P450 3A4enzyme
EthosuximideCytochrome P450 2E1enzyme
EthosuximideCytochrome P450 3A Subfamilyenzyme
1-Ethyl-Pyrrolidine-2,5-DioneVesicle-fusing ATPasetarget
1-Ethyl-Pyrrolidine-2,5-DioneERO1-like protein betatarget
Bisindolylmaleimide VIII3-phosphoinositide-dependent protein kinase 1target
Bisindolylmaleimide VIIIMyotonin-protein kinasetarget
N-EthylmaleimideGalectin-10target
Bisindolylmaleimide ISerine/threonine-protein kinase pim-1target
Bisindolylmaleimide I3-phosphoinositide-dependent protein kinase 1target
Bisindolylmaleimide IProtein kinase C iota typetarget
Bis(N-maleimidomethyl)etherAzurintarget
MethsuximideCytochrome P450 2C19enzyme
MethsuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget