Penicillin G

Name
Penicillin G
Accession Number
DBCAT000740
Description

A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.

ATC Classification
Drugs
DrugDrug Description
AmpicillinA penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
PhenoxymethylpenicillinA penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues.
CarbenicillinFor the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria.
AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
SulbenicillinNot Annotated
BenzylpenicillinA penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
AzlocillinFor the treatment of infections caused by Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae.
BacampicillinAn ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections.
Procaine benzylpenicillinA local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection.
SultamicillinA mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria.
EpicillinNot Annotated
AspoxicillinNot Annotated
MetampicillinMetampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the...
PiperacillinA penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria.
MezlocillinUsed to treat serious gram–negative infections of the lungs, urinary tract, and skin.
PivampicillinAn ampicillin prodrug used to treat a variety of infections.
CarindacillinA penicillin antibiotic used to treat a variety of infections, but is no longer marketed in the USA.
CarfecillinNot Annotated
TalampicillinNot Annotated
Drugs & Drug Targets
DrugTargetType
AmpicillinSerum albumincarrier
AmpicillinSolute carrier family 22 member 5transporter
AmpicillinSolute carrier family 15 member 1transporter
AmpicillinSolute carrier family 15 member 2transporter
AmpicillinPenicillin-binding protein 2atarget
AmpicillinPenicillin-binding protein 1btarget
AmpicillinPenicillin-binding protein 3target
AmpicillinPenicillin-binding protein 1Atarget
AmpicillinPenicillin-binding protein 2Btarget
AmpicillinMonocarboxylate transporter 1transporter
AmpicillinSolute carrier family 15 member 1target
AmpicillinSolute carrier family 15 member 2target
AmpicillinAngiopoietin-1 receptortarget
PhenoxymethylpenicillinPenicillin-binding protein 1Atarget
PhenoxymethylpenicillinMecA PBP2' (penicillin binding protein 2')target
PhenoxymethylpenicillinD-alanyl-D-alanine carboxypeptidase DacBtarget
PhenoxymethylpenicillinPenicillin acylasetarget
PhenoxymethylpenicillinSolute carrier family 15 member 1target
CarbenicillinSolute carrier family 22 member 6transporter
CarbenicillinPenicillin-binding proteintarget
CarbenicillinCytosolic phospholipase A2enzyme
CarbenicillinBeta-lactamase Toho-1target
AmoxicillinSolute carrier family 15 member 1transporter
AmoxicillinSolute carrier family 15 member 2transporter
AmoxicillinSolute carrier family 22 member 6transporter
AmoxicillinCytochrome P450 2C8enzyme
AmoxicillinSerum albumincarrier
AmoxicillinBeta-lactamase 2enzyme
AmoxicillinPenicillin binding proteintarget
BenzylpenicillinSolute carrier family 22 member 5transporter
BenzylpenicillinSolute carrier family 15 member 1transporter
BenzylpenicillinSolute carrier family 15 member 2transporter
BenzylpenicillinSolute carrier family 22 member 6transporter
BenzylpenicillinSolute carrier family 22 member 8transporter
BenzylpenicillinSolute carrier family 22 member 4transporter
BenzylpenicillinSolute carrier family 22 member 11transporter
BenzylpenicillinSolute carrier organic anion transporter family member 2B1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 4A1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 3A1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 1B1transporter
BenzylpenicillinPenicillin-binding protein 3target
BenzylpenicillinSolute carrier family 22 member 8target
BenzylpenicillinSolute carrier family 15 member 1target
BenzylpenicillinSolute carrier family 15 member 2target
BenzylpenicillinBeta-lactamase TEMenzyme
BenzylpenicillinSerum albumincarrier
AzlocillinPenicillin-binding protein 1Atarget
BacampicillinPenicillin-binding proteintarget
PiperacillinSolute carrier family 22 member 6transporter
PiperacillinPenicillin-binding protein 3target
PiperacillinPenicillin-binding protein 2Btarget
PiperacillinPenicillin-binding protein 2atarget
PiperacillinPenicillin-binding protein 1btarget
PiperacillinSolute carrier family 22 member 8transporter
MezlocillinPenicillin-binding protein 1Atarget
MezlocillinPenicillin-binding protein 2target
MezlocillinPenicillin-binding protein 3target
PivampicillinPenicillin-binding protein 1Atarget
CarindacillinPenicillin-binding proteintarget