Antipsoriatics for Topical Use

Name
Antipsoriatics for Topical Use
Accession Number
DBCAT002153
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
CalcitriolAn active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
TazaroteneAn acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis.
Fumaric AcidNot Available
CalcipotriolA topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis.
AnthralinAn anthracene used to treat stable plaque psoriasis.
TacalcitolNot Annotated
MethoxsalenA furocoumarin used to treat psoriasis and vitiligo.
TrioxsalenA psoralen derivative that has been used in combination with UV light to treat vitiligo, but has been discontinued by its manufacturer.
Drugs & Drug Targets
DrugTargetType
CalcitriolVitamin D3 receptortarget
Calcitriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CalcitriolCytochrome P450 3A4enzyme
CalcitriolHomeobox protein Hox-A10target
CalcitriolVitamin D-binding proteincarrier
TazaroteneRetinoic acid receptor alphatarget
TazaroteneRetinoic acid receptor RXR-betatarget
TazaroteneRetinoic acid receptor gammatarget
TazaroteneRetinoic acid receptor betatarget
TazaroteneCytochrome P450 2C8enzyme
Fumaric AcidMalate dehydrogenasetarget
Fumaric AcidFumarate reductase flavoprotein subunittarget
Fumaric AcidNAD-dependent malic enzyme, mitochondrialtarget
Fumaric AcidFumarylacetoacetasetarget
Fumaric AcidFumarate reductase flavoprotein subunittarget
CalcipotriolVitamin D3 receptortarget
CalcipotriolMyeloperoxidaseenzyme
Calcipotriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
AnthralinKeratin, type II cytoskeletal 2 epidermaltarget
AnthralinC-Jun-amino-terminal kinase-interacting protein 1target
AnthralinKeratin, type I cytoskeletal 12target
MethoxsalenDNAtarget
MethoxsalenCytochrome P450 2A6enzyme
MethoxsalenCytochrome P450 1A2enzyme
MethoxsalenCytochrome P450 1A1enzyme
MethoxsalenCytochrome P450 2A13enzyme
TrioxsalenDNAtarget