Endocarditis (DBCOND0007468)

Identifiers

Synonyms
Endocarditis NOS / Endocarditis (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Ampicillin
A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
Benzylpenicillin
A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06489535
Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN)No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02443064
Pharmacokinetics/ Pharmacodynamics (PK/PD) Study of Vancomycintreatment4unknown_status
NCT00548002
Combination Therapy With Fluoroquinolone in Staphylococcus Aureus BacteremiaNot AvailableNot Availablecompleted
NCT05613933
Effectiveness of Antibiotic Prophylaxis of Infective Endocarditis for Invasive Dental Procedures in Patients With Prosthetic Heart Valves and/or History of Infective EndocarditisNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT03429153
Management of Infectious Endocarditis as Part of a Multidisciplinary Consensus MeetingNo drug interventionsNot AvailableNot Availableunknown_status
NCT05547607
Clinical and Diagnostic Features of EndocarditisNo drug interventionsNot AvailableNot Availablerecruiting
NCT06107309
Suppressive Antibiotic Therapy for EndocarditisNo drug interventionsNot AvailableNot Availablerecruiting
NCT03148756
Efficacy and Safety of Dalbavancin Compared to Standard of Care Antibiotic Therapy for the Completion of Treatment of Patients With Complicated Bacteremia or Infective Endocarditistreatment2terminated
NCT04068337
Freestyle Prosthesis for Aortic Root-replacement With and Without Hemiarch ReplacementNo drug interventionsNot AvailableNot Availablecompleted
NCT03411499
Stroke-free Survival Comparison Between Early Surgery and Conventional Therapy in Left Infective EndocarditisNo drug interventionstreatmentNot Availableterminated
NCT03231449
A Survey of Hospitalizations in Cardiology Units in Sub-Saharan AfricaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00709358
Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe InfectionsNo drug interventionsdiagnostic4completed
NCT06403839
Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Surgical Valve Replacement PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01375257
Partial Oral Treatment of EndocarditisNo drug interventionstreatment4completed
NCT05378126
Evaluation of the Prognostic Impact of a Neuro-vascular Examination Associated With Cerebral MRI in the Acute Phase of Infectious EndocarditisNo drug interventionshealth_services_researchNot Availablerecruiting
NCT01431326
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of CareNot AvailableNot Availablecompleted
NCT03377465
Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and PrognosisNo drug interventionspreventionNot Availablecompleted
NCT01734694
Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patientsprevention4terminated
NCT02251262
Diagnostic Accuracy of 18FDG-PET-CT for Pacing or Defibrillation Lead InfectionNo drug interventionsdiagnosticNot Availablecompleted
NCT00590889
Artificial Valve Endocarditis Reduction TrialNo drug interventionspreventionNot Availableterminated
NCT02783404
An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Proceduresprevention4terminated
NCT00166023
Outcomes Following Medical or Surgical Management of EndocarditisNo drug interventionsNot AvailableNot Availablecompleted
NCT01301638
Retrospective Evaluation of Safety and Efficacy of Daptomycin Used in Patients With Serious Gram-positive InfectionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT06422221
An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Proceduresprevention4not_yet_recruiting
NCT00995384
Cardiac Computed Tomography (CT) Scan Compared to Transesophageal Echocardiogram (TEE) in EndocarditisNo drug interventionsdiagnosticNot Availableterminated
NCT03695861
Contribution of 18F-FDG PET-CT in the Diagnosis and the Detection of Peripheral Emboli of Infectious Endocarditis on Native ValvesNo drug interventionsdiagnosticNot Availablecompleted
NCT00579761
Retrospective Review of Management of Infective EndocarditisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02759978
Individualized Diagnosis of Endocarditis and Its Therapy With a Focus on Infected Prosthetic materiALNo drug interventionsNot AvailableNot Availableunknown_status
NCT03112356
The Value of 99mTc-Leukoscan® Scintigraphy in the Diagnosis of Infectious Endocarditis on Surgical Materialsdiagnostic4unknown_status
NCT05156437
Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL)treatment4enrolling_by_invitation
NCT03718052
Early Valve Surgery Versus Conventional Treatment in Infective Endocarditis Patients With High Risk of EmbolismNo drug interventionspreventionNot Availablerecruiting
NCT06275100
PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEryNo drug interventionssupportive_careNot Availablerecruiting
NCT05144399
Accelerated Treatment of EndocarditisNo drug interventionstreatment4recruiting
NCT02459613
Assessment of Radiolabeled rhAnnexin V-128 in Infective EndocarditisNo drug interventionsdiagnostic1 / 2terminated
NCT04387513
Impact of Early Cardiac Surgery in Severe Left Endocarditis With Neurological Complications: a Retrospective StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05474118
Real-life Use of Cefazolin for the Treatment of Meticillin-susceptible Staphylococcal Infective Endocarditis: Comparison to a Treatment Cohort With Penicillin MNo drug interventionsNot AvailableNot Availablecompleted
NCT05703022
Early Exercise Training in Patients Following Heart Valve Surgery for Infective Endocarditis.No drug interventionstreatmentNot Availablerecruiting
NCT06330766
Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Transcatheter Aortic Valve Implantation PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT03892174
Cytokine REmoval in CRitically Ill pAtients Requiring Surgical Therapy for Infective Endocarditis (RECReATE)No drug interventionstreatmentNot Availablerecruiting
NCT00750373
Early Surgery Versus Conventional Treatment in Infective EndocarditisNo drug interventionstreatment4completed
NCT05432427
64Cu-DOTATATE PET-CT-skanning and Infective Endocarditis.No drug interventionsdiagnosticNot Availablerecruiting
NCT03690076
Human Cardiac Mitochondria in Acute Endocarditis and ObesityNo drug interventionsNot AvailableNot Availableunknown_status
NCT04309591
Cytosorb Therapy in Cardiac SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT05142891
Renal Tolerance of Amoxicillin and Cloxacillin CombinationNo drug interventionsNot AvailableNot Availableunknown_status
NCT05146180
Interest of Parametric Positron Emission Imaging in the Diagnosis of Infections on Cardiac Valve ProsthesisNo drug interventionsdiagnosticNot Availablerecruiting
NCT05139589
The ENDOCARDITIS AUMC Data CollectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT06434012
Barts Endocarditis Research RegistryNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02026895
Virulence of Staphylococcus Lugdunensis in Severe InfectionsNo drug interventionsbasic_scienceNot Availablecompleted