Productive cough (DBCOND0019605)
Identifiers
- Synonyms
- Productive cough (finding)
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Ammonium chloride Expectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium...No drug targets Chlorpheniramine A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.- Histamine H1 receptortarget
- Cytochrome P450 3A4enzyme
- Cytochrome P450 2D6enzyme
- Sodium-dependent serotonin transportertarget
- Sodium-dependent noradrenaline transportertarget
- Sodium-dependent dopamine transportertarget
- Cytochrome P450 3A5enzyme
- Cytochrome P450 3A7enzyme
- Solute carrier family 22 member 2transporter
- Solute carrier family 22 member 1transporter
Diphenhydramine A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.- Histamine H1 receptortarget
- Cytochrome P450 2D6enzyme
- Cytochrome P450 2C9enzyme
- Cytochrome P450 2C19enzyme
- Solute carrier family 22 member 2transporter
- Organic cation/carnitine transporter 2transporter
- Prostaglandin G/H synthase 1enzyme
- Muscarinic acetylcholine receptor M2target
- Histamine N-methyltransferasetarget
Guaiacol It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a...- Albumintarget
Guaifenesin An expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.- NMDA receptortarget
Hedera helix leaf extract A plant extract indicated to treat coughing.No drug targets Levomenthol An organic compound used to treat mild to moderate muscle and joint pain.- Transient receptor potential cation channel subfamily A member 1target
- Transient receptor potential cation channel subfamily M member 8target
- Transient receptor potential cation channel subfamily V member 3target
- Kappa-type opioid receptortarget
- Voltage-dependent L-type calcium channeltarget
- Cytochrome P450 3A4enzyme
Terbutaline A beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.- Beta-2 adrenergic receptortarget
- Cholinesteraseenzyme
- Beta-3 adrenergic receptortarget
- Beta-1 adrenergic receptortarget
- Sulfotransferaseenzyme
- UDP-glucuronosyltransferases (UGTs)enzyme
- Organic cation/carnitine transporter 2transporter
- Solute carrier family 22 member 2transporter
- Clinical Trials
- Not Available