Bloodstream Infections (BSI) (DBCOND0079192)

Identifiers

Synonyms
Infection, Bloodstream / Bloodstream Infections / Bloodstream Infection (BSI) / Blood Stream Infections / Bloodstream Infection / Blood-stream Infections / Blood Stream Infection / Infection systemic / Systemic infection / Sepsis / Systemic infection (disorder) / Sepsis NOS / Infection of bloodstream (disorder) / Haematological infection / Hematological infection

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Anidulafungin
An antifungal used in the treatment of several types of candida infections.
Benzylpenicillin
A penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
Cefoperazone
A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.
Cefradine
A first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues.
Teicoplanin
A glycopeptide antibiotic with a similar mechanism of action and spectrum of activity to vancomycin used to treat various infections caused by gram-positive bacteria.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06126263
Adjunctive Clindamycin Versus Linezolid for β-lactam Treated Patients With Invasive Group A Streptococcal InfectionsNot AvailableNot Availableactive_not_recruiting
NCT05876598
BACTERIUM: Study for a Machine-learning-based Model to Predict Bloodstream InfectionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02437045
Trial of Meropenem Versus Piperacillin-Tazobactam on Mortality and Clinial Responsetreatment4completed
NCT03869437
RCT Cefiderocol vs BAT for Treatment of Gram Negative BSItreatment2completed
NCT02176122
RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp.treatment4terminated
NCT01576003
Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome InfantstreatmentNot Availablecompleted
NCT04156633
Clinical Impact of Rapid Identification of Positive Blood Cultures vs. Internal Laboratory StandardNo drug interventionsNot AvailableNot Availablecompleted
NCT06418048
INfectious DIsease REgistry BIObankNo drug interventionsNot AvailableNot Availablerecruiting
NCT04548167
Prolonged Cardiopulmonary Bypass Time as Predictive Factor for in Hospital InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT02443064
Pharmacokinetics/ Pharmacodynamics (PK/PD) Study of Vancomycintreatment4unknown_status
NCT02578875
Evaluation of MiSeq for Microbial Identification in SpecimensNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01409772
Evaluation of 70% Ethanol Lock Solution to Prevent Catheter Related Blood Stream Infections in Pediatric PatientsNot AvailableNot Availablewithdrawn
NCT05979545
EaRly impAct theraPy With Ceftazidime-avibactam Via rapID DiagnosticsNo drug interventionstreatment4recruiting
NCT02689193
IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating CentresNo drug interventionsNot AvailableNot Availablecompleted
NCT01077336
Clinical Outcomes in Candidemia Patients Based on in Vitro SusceptibilityNo drug interventionsNot AvailableNot Availablecompleted
NCT00990392
Topical Antibiotics for Prevention of Intensive Care Unit (ICU) Central Line InfectionspreventionNot Availablewithdrawn
NCT01255943
Testing Spread and Implementation of Novel Methicillin Resistant Staphylococcal Aureus (MRSA)-Reducing PracticesNo drug interventionsNot AvailableNot Availablecompleted
NCT04083443
Model for PK/PD of Antimicrobials in Blood Stream Infection: FeasibilityNo drug interventionsNot AvailableNot Availableunknown_status
NCT02714595
Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogenstreatment3completed
NCT04335539
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participantstreatment2completed
NCT06174649
Fast Antibiotic Susceptibility Testing for Gram Negative Bacteremia TrialNo drug interventionsdiagnosticNot Availablerecruiting
NCT06271031
Process Mapping and Data Collection to Inform a Computer Simulation Model of Hospitalised Patients With Bloodstream Infection, Sepsis and Systemic InfectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT06489535
Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN)No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05210387
Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli InfectionsNo drug interventionstreatmentNot Availableterminated
NCT04839653
Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant BacteriapreventionNot Availableunknown_status
NCT04229498
Comparison of Bloodstream Infections With Carbapenem Hetero-resistant vs Carbapenem Resistant Klebsiella PneumoniaeNo drug interventionsNot AvailableNot Availableunknown_status
NCT04910698
Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile NeutropeniaNo drug interventionsNot AvailableNot Availablecompleted
NCT03744728
Genotypic Versus Phenotypic Susceptibility Testing of Positive Blood CulturesNo drug interventionsdiagnosticNot Availableunknown_status
NCT03147807
BetaLACTA® Test for Early De-escalation of Empirical Carbapenems in Pulmonary, Urinary and Bloodstream Infections in ICUNo drug interventionstreatmentNot Availablecompleted
NCT03255759
Actionable Results: Bloodstream Infection Molecular Assay EvaluationNo drug interventionsdiagnosticNot Availablecompleted
NCT00680459
Ethanol Locks for the Treatment of Central Venous Line Infectionstreatment3terminated
NCT06069206
Effect of Direct-from-blood Bacterial Testing on Antibiotic Administration and Clinical OutcomesNo drug interventionshealth_services_researchNot Availablerecruiting
NCT05270135
ASAP: Access to Syringes at Pharmacies for the Prevention of Bloodborne Infections Among People Who Inject DrugsNo drug interventionspreventionNot Availablecompleted
NCT04070820
Combination Treatment for Enterococcus Faecalis Bacteriemia Multicenter, Observational Study"No drug interventionsNot AvailableNot Availableunknown_status
NCT06531031
Clinical Performance Study of Microbio InfectID-BSI for Detection of Bacteria and Yeast With Patient Blood SamplesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00467272
Catheter Related - Gram Positive Bloodstream Infectionstreatment2completed
NCT04250168
Piloting Clinical Bacteriology in the Ebola Virus Disease Care ResponseNo drug interventionsNot AvailableNot Availableterminated
NCT05880069
Clinical Outcomes in Patients With Infection by Resistant MicroorganismNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02516514
The Only Blood Culture for Diagnosis of Bacteremia - Comparative Study of PracticeNo drug interventionsdiagnosticNot Availablecompleted
NCT05277350
A Study Investigating the Safety, Recovery, and Pharmacodynamics of Multiple Oral Administrations of SNIPR001 in Healthy SubjectsNo drug interventionsother1completed
NCT00870623
Procalcitonin and Endotoxin Sequential Levels to Optimize the Treatment of Bloodstream InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT04229511
Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03896893
Neonatal Bacterial Colonization StudyNo drug interventionspreventionNot Availableunknown_status
NCT03991793
Granzyme A in Patients With E. Coli Bacteremic Urinary Tract InfectionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04289688
Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR CongoNo drug interventionsNot AvailableNot Availablecompleted
NCT06160115
The Role of NK Cells to Detect Blood Infection in ALL.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05411315
Pragmatic Randomized Trial for Arterial Catheters in the Critical Care EnvironmentNo drug interventionspreventionNot Availablecompleted
NCT04658017
GARNET™ Filter (GARNET Device) IDE Used in Chronic Hemodialysis Patients With a Bloodstream InfectionNo drug interventionstreatmentNot Availableunknown_status
NCT06576258
The Clinical Impact of Cobas® Eplex Blood Culture Panels for the Diagnosis of Bacteremia and FungemiaNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT03226158
Next Generation Pathogen Sequencing for Prediction of Adverse EventsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03578835
Bloodstream Infection Due to Multidrug-Resistant Organisms - Multicenter Study on Determinants of Clinical OutcomesNo drug interventionsNot AvailableNot Availableunknown_status
NCT04926935
Bloodstram Infections in ICU. Single Centre Observational Study.No drug interventionsNot AvailableNot Availablecompleted
NCT05361135
18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in S. Aureus BacteraemiaNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT01544686
Antimicrobial Catheter Securement Dressings for the Prevention of Cvc-related Bloodstream Infections in Cancer PatientsNo drug interventionspreventionNot Availablecompleted
NCT05210439
Efficacy and Safety of 7 Versus 14 Days of Antibiotic Treatment for Pseudomonas Aeruginosa BacteraemiaNo drug interventionstreatment4recruiting
NCT04876430
Best Available Therapy With or Without Meropenem for Bloodstream Infections by Enterobacterales With High Level of Resistance to Carbapenemstreatment2 / 3terminated
NCT03896880
Detection of Bloodstream Pathogens in Hematological MalignanciesNo drug interventionsNot AvailableNot Availablecompleted
NCT04260789
Reduction of Pathogen Load From the Blood in Septic Patients With Suspected, Life-threatening Bloodstream InfectionNo drug interventionstreatmentNot Availableunknown_status
NCT00843804
Surveillance for Nosocomial Infections in Pediatric Cancer PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02400268
Antibiotic Treatment Duration (7 vs 14 Days) Comparison in Blood Stream Infection Causes by EnterobacteriaceaeNo drug interventionstreatment3completed
NCT04473768
Clinical Decision Support in Non-typhoidal Salmonella Bloodstream Infections in ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT04710212
Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic MalignanciesNo drug interventionsNot AvailableNot Availablecompleted
NCT01898208
Rapid Identification and Susceptibility Testing of Pathogens From Blood CulturesNo drug interventionsdiagnosticNot Availablecompleted
NCT04850677
Treating Non-typhoidal Salmonella Bloodstream Infections in Children Under Five in DR Congo: a Cohort StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03284398
Three-Chamber Bags Retrospective Study in SpainNo drug interventionsNot AvailableNot Availablecompleted
NCT02743585
Impact of Rapid Pathogen Identification From Blood Cultures (RABbIT)No drug interventionsdiagnosticNot Availableunknown_status
NCT05016752
Application of Nanopore Sequencing in Newly Diagnosed Acute Myeloid Leukemia Patients With Bloodstream InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT01396642
Topical Emollient TherapyNo drug interventionspreventionNot Availablecompleted
NCT03379948
Central and Peripheral Venous Catheters Associated Blood Stream Infection in ICU in Assiut UniversityNo drug interventionsNot AvailableNot Availableunknown_status
NCT01597973
Trial for the Treatment of Extensively Drug-Resistant Gram-negative Bacilli (OVERCOME)treatment3completed
NCT02682355
Optimizing Clinical Use of Polymyxin BNo drug interventionsNot AvailableNot Availablecompleted