NCT06605131
GP Combined with Toripalimab Versus GP Induction Chemotherapy for Advanced Childhood Nasopharyngeal Carcinoma treatment 2 not_yet_recruiting NCT02586532
Evaluation of the Sensitivity of Endoscopy to Detect Nasopharyngeal Carcinoma (NPC) in an Epstein-Barr Virus (EBV)-Based NPC Screening Project in China No drug interventions Not Available Not Available completed NCT06475300
A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors No drug interventions treatment 2 recruiting NCT06572293
Effect of Nurse-Led Individualized Follow-Up Intervention on Patients With Nasopharyngeal Carcinoma No drug interventions treatment Not Available not_yet_recruiting NCT06629597
A Phase III Study of YL201 in Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 3 not_yet_recruiting NCT02834013
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors treatment 2 active_not_recruiting NCT03891953
Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors. treatment 1 active_not_recruiting NCT04242199
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors No drug interventions treatment 1 active_not_recruiting NCT04509726
EBV Specific Cytokine Secreting TCR-T Cells in the Treatment of EBV-Positive Metastatic/Refractory Nasopharyngeal Carcinoma No drug interventions treatment 1 / 2 suspended NCT05166577
Nanatinostat Plus Valganciclovir in Patients with Advanced EBV+ Solid Tumors, and in Combination with Pembrolizumab in EBV+ RM-NPC treatment 1 / 2 active_not_recruiting NCT06463392
Deep Learning-based sbORN Diagnostic Model No drug interventions Not Available Not Available recruiting NCT04895345
A Study of TQB2450 in Combination With Intensity-modulated Radiotherapy in Patients With Inoperable Locally Recurrent Nasopharyngeal Carcinoma treatment 2 completed NCT05517135
tReatment Individualisation By EBV stratificatiON in Nasopharyngeal Carcinoma: an Umbrella Platform Study (RIBBON-Umbrella) No drug interventions Not Available Not Available recruiting NCT06592599
Gemcitabine + Docetaxel + Toripalimab Induction in Epstein-Barr Virus (EBV) Associated Nasopharyngeal Carcinoma(NPC) treatment 2 recruiting NCT05682703
A Bidirectional Study in Exploring the Dynamic Changes of Plasma and Urine Metabolites of Nasopharyngeal Carcinoma. No drug interventions Not Available Not Available recruiting NCT03588403
TOMO Versus IMRT in Nasopharyngeal Carcinoma Patients No drug interventions Not Available Not Available unknown_status NCT01854203
Combination of Cisplatin Plus Gemcitabine Induction Chemotherapy and Intensity-modulated radiotherapyIntensity-modulated Radiotherapy With or Without Concurrent Cisplatin for NPC treatment 2 / 3 unknown_status NCT06480903
Exploratory Study of EBV DNA Titre Clearance Whilst on Proton Beam Therapy No drug interventions Not Available Not Available not_yet_recruiting NCT04292990
Comparison of Transdermal Fentanyl and Morphine for Oral Mucositis Pain in Nasopharyngeal Cancer Patients treatment 4 unknown_status NCT01417390
Study of Neoadjuvant Gemcitabine and Cisplatin in Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 unknown_status NCT04825990
Pembrolizumab and Olaparib in Recurrent/Metastatic, Platinum Resistant Nasopharyngeal Cancer treatment 2 recruiting NCT03925090
Phase II Trial of Neoadjuvant and Adjuvant Anti-PD-1 Antibody Toripalimab Combined With CCRT in NPC Patients treatment 2 active_not_recruiting NCT06170021
Occurrence of Radiation-induced Otitis Media in Nasopharyngeal Carcinoma Patients After Intensity Modulated Radiotherapy No drug interventions Not Available Not Available recruiting NCT03840421
GP vs PF as Induction Chemotherapy Combined With CCRT for Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 active_not_recruiting NCT05352321
Surgery Plus Target-reduction Chemoradiotherapy vs Regular Chemoradiotherapy for Newly Diagnosed Resectable Nasopharyngeal Carcinoma treatment Not Available recruiting NCT04143984
Carbon-Ion Radiotherapy Plus Camrelizumab for Locally Recurrent Nasopharyngeal Carcinoma treatment 2 recruiting NCT03529279
CNG Staging Compared With 8th UICC of NPC for Treatment Decision-marking and Selection of Chemotherapy and Radiotherapy No drug interventions treatment 3 not_yet_recruiting NCT00516087
LMP1- and LMP2-Specific CTLs to Patients With EBV-Positive NPC (NATELLA) No drug interventions treatment 1 completed NCT05956587
A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors No drug interventions treatment 2 recruiting NCT03213587
Apatinib in Treating Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC) treatment 2 unknown_status NCT02590133
A Phase II Clinical Trial of Chemotherapy With or Without Endostar® Continuous Intravenous Infusion in Refractory NPC treatment 2 unknown_status NCT01309633
Study Evaluating Two Loading Regimens of Sunitinib or Bevacizumab Alternating With Cisplatin and Gemcitabine as Induction Therapy for Locally Advanced Nasopharyngeal Carcinoma (NPC) treatment 2 completed NCT06118333
A Study Comparing BL-B01D1 With Physician's Choice of Chemotherapy in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 3 recruiting NCT03411954
Hippocampus Avoidance During Intensity Modulated Radiotherapy for T4 Nasopharyngeal Carcinoma Patients No drug interventions Not Available Not Available unknown_status NCT03314051
Long-term Treatment Outcome for Stage III NPC Patients and Risk Grouping by Plasma EBV DNA No drug interventions Not Available Not Available completed NCT05654077
EBV CAR-T Cells for Nasopharyngeal Carcinoma treatment 0 recruiting NCT05508347
Nituzumab (Taixinsheng ®） A Prospective, Randomized, Double-blind, Placebo-controlled, Multicenter Phase II Clinical Study on the Efficacy and Safety of Combined Induction Chemotherapy for Locally Advanced Nasopharyngeal Carcinomatreatment of Locally Advanced Nasopharyngeal Carcinoma No drug interventions treatment 2 unknown_status NCT05955105
A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies treatment 1 / 2 recruiting NCT05674305
Radiotherapy Alone Versus Concurrent Chemo-radiotherapy for Nasopharyngeal Carcincoma Patients With Undectable EBV DNA After One Cylce Neoadjuvant Chemotherpy treatment 3 recruiting NCT03989297
PD-L1 and BRAF Expression in Nasopharyngeal Carcinoma No drug interventions Not Available Not Available completed NCT04015661
Induction Chemotherapy Followed by Concurrent Chemoradiotherapy in Patients With LA-NPC treatment 2 unknown_status NCT02328261
A Phase II Study of Icotinib in Treating Patients With Advanced Nasopharyngeal Carcinoma treatment 2 unknown_status NCT06059261
Envafolimab Combined With Chemoradiotherapy and Recombinant Human Endostatin for LA-NPC. treatment 2 recruiting NCT02698111
Donafenib Monotherapy for Previously Treated Metastatic Nasopharyngeal Carcinoma treatment 1 / 2 terminated NCT00834093
A Phase II Study of Epstein-Barr Virus-Specific Immunotherapy for Nasopharyngeal Carcinoma treatment 2 completed NCT06097793
KSD-101 Therapy for EBV-associated Nasopharyngeal Carcinoma: an Exploratory Clinical Trial No drug interventions treatment 0 recruiting NCT02501993
Nasopharyngeal Carcinoma Screening in Zhongshan City No drug interventions Not Available Not Available active_not_recruiting NCT03283293
Target Volume Delineation After NACT in LA-NPCarcinoma Patients Treated With NACT+ CCRT No drug interventions treatment 2 completed NCT04319471
Sufficient Chemotherapy Combine With Maintenance Chemotherapy in the Treatment of Oligometastatic Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05547971
Development of Intelligent Model for Radioactive Brain Damage of Nasopharyngeal Carcinoma Based on Radio-metabolomics No drug interventions Not Available Not Available unknown_status NCT05008471
Application of Whole-course Standardized Nutrition Management During Peri-radiotherapy in Patients With Nasopharyngeal Carcinoma After Radiotherapy: a Multicenter Randomized Controlled Clinical Study No drug interventions prevention Not Available unknown_status NCT04004871
Induction Chemotherapy With Nab-paclitaxel, Cisplatin and Fluorouracil for Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 unknown_status NCT06156878
PD-1 Inhibitor Plus Anti-EGFR Therapy And Radiotherapy in Locally Advanced NPC Resistant to Induction Chemotherapy No drug interventions treatment 2 recruiting NCT04547088
Camrelizumab Combined With Apatinib in Patients With First-line Platinum-resistant Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 2 unknown_status NCT03006588
EUS-FNA for Retropharyngeal Lymph Node (RPLN) in Recurrent Nasopharyngeal Carcinoma (NPC) Patients No drug interventions diagnostic 2 / 3 unknown_status NCT06445088
Diagnostic Accuracy of EBV C Promoter Methylation Kit in Nasopharyngeal Carcinoma No drug interventions Not Available Not Available recruiting NCT06383507
A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors No drug interventions treatment 1 not_yet_recruiting NCT04072107
EPstein-barr Virus DNA Response to Systemic Therapy for Treatment Adaptation in High Risk NPC (EP-STAR) treatment 2 active_not_recruiting NCT04220307
A Study of a PD-1/CTLA-4 Bispecific Antibody AK104 in Patients With Metastatic Nasopharyngeal Carcinoma treatment 2 completed NCT06442709
Combined Anti-IL6R and Anticoagulation Therapy in Advanced NPC Patients treatment Not Available active_not_recruiting NCT01182909
Environmental and Genetic Determinants of Nasopharyngeal Carcinoma (NPC) No drug interventions Not Available Not Available unknown_status NCT05097209
Camrelizumab for the Treatment of Locally Advanced Nasopharyngeal Carcinoma treatment 2 recruiting NCT01344356
Stereotactic Body Radiotherapy for Head and Neck Tumors No drug interventions treatment 4 completed NCT04417985
Prognostic Utility of the Imaging and Biological Signatures in Nasopharyngeal Carcinoma No drug interventions other Not Available completed NCT02187315
Induction Chemotherapy Followed By Chrono-chemotherapy Concurrent With IMRT Of Locally Advanced NPC Clinical Study treatment 2 unknown_status NCT02512315
A Trial On 4 Cycles Of Neoadjuvant Chemotherapy Plus Concurrent Chemoradiation In N2-3 Nasopharyngeal Carcinoma treatment 3 recruiting NCT03058432
Concurrent Chemotherapy for Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma No drug interventions treatment 2 unknown_status NCT02199132
Retrospective Study About Nasopharyngeal Carcinoma at C. S. Parc Tauli No drug interventions Not Available Not Available completed NCT04636632
Fosaprepitant for the Prevention of Nausea and Emesis During Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma prevention 1 completed NCT02363400
A Phase III Trial in NPC With Post-radiation Detectable Plasma EBV DNA treatment 3 unknown_status NCT04085900
Screening Nasopharyngeal Carcinoma With EBV Associated Biomarkers in Zhongshan City No drug interventions Not Available Not Available recruiting NCT04766359
Paclitaxel (Albumin-bound) Combined With Radiotherapy for the Treatment of Early Stage Nasopharyngeal Carcinoma treatment 3 not_yet_recruiting NCT05201859
Adjuvant Sintilimab Plus Capecitabine in Nasopharyngeal Carcinoma treatment 2 recruiting NCT03427359
Induction Cisplatin and Capecitabine Followed by Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma treatment 2 completed NCT01245959
Induction Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT04303975
The Association of hsCRP and Radiotherapy-Induced Toxicity in Patients With Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT03578575
To Investigate the Molecular Mechanism of Traditional Chinese Medicine Constitution Using Next-generation Sequencing in Nasopharyngeal Carcinoma treatment 2 unknown_status NCT03601975
Gemcitabine and Cisplatin With/Without Anlotinib in Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT02621970
Effect of Triple Combination of Induction, Concurrent and Adjuvant Chemotherapy in High Risk Nasopharyngeal Carcinoma treatment 3 unknown_status NCT05994170
Reducing High Risk Primary Tumor Clinical Target Volumes (CTVp1) in Non-metastatic Nasopharyngeal Carcinoma No drug interventions treatment Not Available recruiting NCT03923842
Denosumab In Ebv Nasopharyngeal Carcinoma As A Model For RankMediated Immunologic Modulation Of Virus-Related Tumours treatment 2 unknown_status NCT04107142
Haplo / Allogeneic NKG2DL-targeting Chimeric Antigen Receptor-grafted γδ T Cells for Relapsed or Refractory Solid Tumour No drug interventions other 1 unknown_status NCT03544099
Pembrolizumab for Nasopharyngeal Carcinoma Patients With Detectable Plasma Epstein-Barr Virus DNA treatment 2 terminated NCT03788499
Using Massage of Maxillofacial and Oral Cavity to Prevent Radioactive Oral Mucositis No drug interventions treatment Not Available completed NCT05389306
Combining MRI and CEUS to Diagnose Small Cervical Lymph Node Metastases in NPC Patients No drug interventions diagnostic Not Available recruiting NCT04834206
Nedaplatin in Treatment for Nasopharyngeal Carcinoma treatment 2 completed NCT04764149
Platinum Plus Low-dose Long-term Continuous Intravenous Infused 5-Fluorouracil in Recurrent Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT00173836
Swallowing Pattern of Patients With Nasopharyngeal Cancer Before and After Radiation Therapy: Longitudinal Study and Correction With Saliva Amount No drug interventions Not Available Not Available completed NCT03503136
Nedaplatin Versus Cisplatin and Capecitabine Versus Fluorouracil in IC + CCRT for Locoregionally Advanced NPC treatment 3 not_yet_recruiting NCT01540136
Concurrent Chemoradiotherapy With Nedaplatin Versus Cisplatin in Nasopharyngeal Carcinoma treatment 3 completed NCT03068936
IMRT Plus Cisplatin Versus IMRT in Patients With Stage 2 Nasopharyngeal Carcinoma treatment 3 unknown_status NCT00367718
Trial of VELCADE in Patients With Metastatic or Locally Recurrent Nasopharyngeal Carcinoma treatment 2 withdrawn NCT04158518
De-escalation Protocols in Locoregionally Advanced Nasopharyngeal Carcinoma No drug interventions treatment Not Available unknown_status NCT02871518
Two Cycles Versus Three Cyclle of CCRT for Low Risk Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05707819
Sintilimab in Combination With Chemoradiotherapy in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma Not Available Not Available recruiting NCT03612219
Adjuvant Treatment of Apatinib in Nasopharyngeal Carcinoma treatment 2 unknown_status NCT02578641
A Phase III Trial Evaluating Chemotherapy and Immunotherapy for Advanced Nasopharyngeal Carcinoma (NPC) Patients treatment 3 completed NCT05941741
IC Plus Low-dose Radiation Plus Cadonilimab in LANPC treatment 3 recruiting NCT02786641
Induction Chemotherapy of TPX in Nomogram-predicted High Risk Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT04745741
Evaluating the Rationality of the International Guideline About Selective Coverage of Level Ib in CTV With NPC No drug interventions Not Available Not Available unknown_status NCT05193617
Penpulimab Combined With GP ± Anlotinib as Neoadjuvant Therapy in Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 active_not_recruiting NCT02016417
Induction Chemotherapy With GP Versus TPF in the Treatment of Advanced Nasopharyngeal Carcinoma treatment 2 unknown_status NCT02776124
Effect of Oral Supplements on the Nutritional Status of Locally Advanced Nasopharyngeal Carcinoma Patients No drug interventions treatment 2 completed NCT06472024
Assessing Manual Acupuncture's Impact on Mucositis From Nasopharynx Cancer Radiotherapy: A Visual Analogue Scale (VAS) and Quality of Life Study No drug interventions treatment Not Available not_yet_recruiting NCT05183724
Ovarian Function of Nasopharyngeal Carcinoma Women Survivors No drug interventions Not Available Not Available not_yet_recruiting NCT04419324
To Evaluate Transoral Flexible Endoscope With Narrow Band Imaging in Nasopharyngeal Cancer No drug interventions screening Not Available unknown_status NCT05531916
Compression Therapy as a Prophylactic Method Against CIPN: a Prospective Self-controlled Trial No drug interventions prevention Not Available recruiting NCT04508816
Anti-EGFR Therapy Plus IMRT Concurrent Chemoradiotherapy in Locally Advanced NPC Resistant to Induction Chemotherapy treatment 2 completed NCT06055816
Gemcitabine Combined With Endostar and Envafolimab in Elderly Patients With Locally Advanced Nasopharyngeal Carcinoma treatment 2 recruiting NCT04221516
Camrelizumab After Completion of Radiotherapy for Oligometastatic Nasopharyngeal Carcinoma treatment 2 recruiting NCT03830996
Weekly Plasma EBV DNA for Non-metastatic Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT00201396
A Multicenter Trial Comparing Induction C/T Followed by CCRT v.s. CCRT Alone in Stage IV Nasopharyngeal Carcinoma treatment 3 completed NCT04996758
Toripalimab and Anlotinib Combination Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma After Failure of at Least One Line of Platinum-Based Chemotherapy (TORAL) treatment 2 active_not_recruiting NCT02401763
Investigating the Role of Mucin and Mucin Glycosylating Enzymes in Nasopharyngeal Carcinoma and Salivary Gland Cancer and Their Correlation With Clinical Prognosis No drug interventions Not Available Not Available unknown_status NCT04136886
Concurrent Chemotherapy for Recurrent T3/T4 Nasopharyngeal Carcinoma treatment 3 recruiting NCT04955886
Surufatinib Combined With Toripalimab in Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 2 unknown_status NCT04396886
Bintrafusp Alfa in Previously Treated Patients With R/M Non-keratinizing NPC treatment 2 completed NCT05417139
Sintilimab Combined With Chemotherapy and Radiotherapy in Newly Diagnosed Metastatic Nasopharyngeal Carcinoma: A Multicenter Study No drug interventions treatment 2 not_yet_recruiting NCT06321939
Sequencing-based Counting of Plasma Epstein-Barr Virus DNA in Non-metastatic Nasopharyngeal Carcinoma No drug interventions Not Available Not Available recruiting NCT03321539
Phase Ⅲ Trial of Adjuvant Chemotherapy in Patients With N2-3 Nasopharyngeal Carcinoma No drug interventions treatment 3 active_not_recruiting NCT03708822
Study of Docetaxel and Cisplatin Combined With Nimotuzumab As First-Line Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 2 active_not_recruiting NCT05721222
PRO1160 for Advanced Solid and Liquid Tumors (PRO1160-001) No drug interventions treatment 1 / 2 recruiting NCT04448522
Reduced vs Conventional Dosage Intensity-modulated Radiotherapy for Chemotherapy-sensitive Stage II-III Nasopharyngeal Carcinoma No drug interventions treatment 3 recruiting NCT04890522
An Open-label, Multicentre, Phase II/III RCT of PFLL Versus GP Combined With JS001 as the First-line Therapy for mNPC treatment 2 / 3 not_yet_recruiting NCT04456322
Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma treatment 3 recruiting NCT05020925
SHR-1701 in Combination With Famitinib in Patients With Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 1 / 2 unknown_status NCT02537925
The Effect of COX-2 Inhibitor on Radiosensitivity in Nasopharyngeal Carcinoma treatment 3 unknown_status NCT03904225
Tegio Consolidation Therapy for NPC Patients With High Risk of Metastasis treatment 2 unknown_status NCT06019130
Nivolumab in Children and Adults With Nasopharyngeal Carcinoma treatment 2 recruiting NCT02523430
HepaSphere Interventional Therapy Using Digital Subtraction Angiography（DSA） for Nasopharyngeal Carcinoma No drug interventions treatment 1 / 2 completed NCT06182657
The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC No drug interventions Not Available Not Available recruiting NCT04833257
Neoadjuvant Therapy of GP Chemotherapy Combined With Tislelizumab in Locoregionally Advanced NPC treatment 2 recruiting NCT06092957
Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy treatment 3 recruiting NCT03984357
Nivolumab Combined With Chemoradiotherapy Sparing Concurrent Cisplatin in Nasopharyngeal Carcinoma treatment 2 active_not_recruiting NCT05202626
Detection and Biopsy Guidance of Nasopharyngeal Carcinoma Based on Artificial Intelligence and Endoscopic Images No drug interventions Not Available Not Available recruiting NCT06364826
Sintilimab Combination Therapy Plus IMRT in Nasopharyngeal Carcinoma treatment 2 not_yet_recruiting NCT03932266
Endostar Combined With Induction Chemotherapy and Concurrent Chemoradiotherapy for Locoregional Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05549466
Targeted or Chemotherapy Combined With Immunotherapy Versus Chemotherapy for PD-1 Inhibitor Refractory R/M NPC treatment 2 recruiting NCT04414566
Induction Chemotherapy Plus Radiotherapy Alone in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 not_yet_recruiting NCT03668366
S-1 Combined With IMRT Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma No drug interventions treatment 2 completed NCT06301165
TPC Versus GP Induction Chemotherapy for Nasopharyngeal Carcinoma No drug interventions treatment 2 recruiting NCT05622474
A Multicenter Randomized Controlled Clinical Study on the Treatment of T3N1M0 High Risk Nasopharyngeal Carcinoma With or Without Induction Chemotherapy Before Concurrent Radiotherapy and Chemotherapy No drug interventions treatment Not Available not_yet_recruiting NCT04898374
Induction Versus Adjuvant Gemcitabine/Cisplatin in Locally Advanced Non-metastatic Nasopharyngeal Carcinoma treatment 3 recruiting NCT00181220
Valproic Acid in the Induction of EBV Lytic Cycle Antigen Expression in Nasopharyngeal Carcinoma treatment 1 withdrawn NCT00953420
Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes treatment 2 completed NCT03290820
Aspirin Improve Survival of N2-3 Nasopharyngeal Carcinoma Patients treatment 2 not_yet_recruiting NCT06189482
Intermittent Oral-esophageal Tube Feeding in Delayed Dysphagia After Radiotherapy for Nasopharyngeal Carcinoma No drug interventions treatment Not Available terminated NCT02636231
Endostar for Locally Recurrent Nasopharyngeal Carcinoma treatment 2 unknown_status NCT06438627
Efficacy and Safety of TPC+Apatinib+Camrelizumab vs GP+ Camrelizumab for High-Risk Nasopharyngeal Carcinoma: A Phase 3 Trial treatment 3 recruiting NCT04769076
The Paclitaxel (Albumin-bound) Combined With Cisplatin, PD-1 Inhibitors and IMRT in the Treatment of Nasopharyngeal Carcinoma treatment 2 not_yet_recruiting NCT02633176
Cisplatin Plus Docetaxel Versus Cetuximab, Cisplatin, and Docetaxel in Metastatic Nasopharyngeal Carcinoma treatment 3 unknown_status NCT01694576
NPC Staged N2-3M0:Adjuvant Chemotherapy or Just Observation After Concurrent Chemoradiation treatment 2 terminated NCT06197776
Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for r/m NPC Not Available Not Available not_yet_recruiting NCT05145660
Optimization of Cervical Nodal CTV for Early and Medium Stage NPC No drug interventions treatment 3 recruiting NCT05126160
Immune Score Based Radiomics in Nasopharyngeal Carcinoma No drug interventions Not Available Not Available recruiting NCT05780294
A Multi-center, Randomized, Double-blind, Phase III Clinical Trial of Leucogen Versus Placebo on Leukocyte and Platelet Whole-course Management Assisted by PFLL Chemotherapy in the Treatment of Stage IV, Recurrent or Metastatic NPC prevention 3 not_yet_recruiting NCT04528394
Proton Versus Photon Radiotherapy for Nasopharyngeal Carcinoma No drug interventions treatment 2 unknown_status NCT02761291
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 1 unknown_status NCT04394091
Post-treatment Ultrasensitive Positron Emission Tomography in Nasopharyngeal Carcinoma Patients No drug interventions Not Available Not Available unknown_status NCT03558191
SHR-1210 in Recurrent/Metastatic Nasopharyngeal Carcinoma Who Have Received Previous At Least Two Lines of Chemotherapy. treatment 2 completed NCT05340491
Chemoradiotherapy Plus Anti-PD1 in Recurrent NPC: A Multicenter, Open-label, Randomised, Controlled, Phase III Trial treatment 3 recruiting NCT04605562
Umbrella Biomarker-Guided Therapy in NPC treatment 2 not_yet_recruiting NCT06529562
Surgery Plus Reduced Target Chemoradiotherapy vs Surgery Plus Reduced Dose Chemoradiotherapy for Newly Diagnosed Operable Nasopharyngeal Carcinoma. No drug interventions treatment Not Available recruiting NCT00364962
Treatment Result of KTP Laser Nasopharyngectomy in Recurrent NPC Patients No drug interventions Not Available Not Available unknown_status NCT01872962
Induction Gemcitabine and Cisplatin in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT00379262
Therapeutic Gain by Induction-concurrent Chemoradiotherapy and/or Accelerated Fractionation for Nasopharyngeal Carcinoma treatment 3 completed NCT06136962
Nasopharyngeal Carcinoma Treated With Reduced Volume Intensity Modulated Radiation Therapy:10-Year Outcome and Late Toxicity, Quality of Life No drug interventions Not Available Not Available not_yet_recruiting NCT02044562
Dietary Nitrate on Plasma Nitrate Levels for Nasopharyngeal Carcinoma Patients No drug interventions treatment Not Available unknown_status NCT01621880
Effect of Bevacizumab on Radiation-induced Brain Necrosis in Patients With Nasopharyngeal Carcinoma treatment 2 completed NCT02096380
The Value of Single-cycle TPF Induction Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma Not Available Not Available unknown_status NCT03020329
Induction Chemotherapy in Young Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 unknown_status NCT03403829
Maintenance Chemotherapy in High-metastatic Risk Nasopharyngeal Carcinoma Patients of N3 Stage treatment 3 unknown_status NCT04437329
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma treatment 3 recruiting NCT02481089
Polymorphisms in Key Genes of Glycolytic Pathway: Influence on Radiosensitivity in Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT05342792
Metronomic Capecitabine With or Without PD-1 Antibody as Adjuvant Therapy in High-risk Nasopharyngeal Carcinoma treatment 3 recruiting NCT00201344
A Phase III Study of Radiotherapy With or Without Adjuvant C/T in Advanced Stage Nasopharyngeal Carcinoma Patients treatment 3 terminated NCT00700440
Study of Cetuximab in Nasopharyngeal Carcinoma (NPC) With Chemoradiotherapy treatment 2 completed NCT03720340
Interleukin-11 Can Prevent and Treat of Radioactive Oral Mucitis treatment 3 unknown_status NCT02421640
Phase II Trial of TIL Following CCRT in Patients With Locoregionally Advanced NPC treatment 2 unknown_status NCT06248840
Intermittent Oral-esophageal Tube in Delayed Dysphagia After Radiotherapy for Nasopharyngeal Carcinoma No drug interventions supportive_care Not Available terminated NCT02605967
Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 2 completed NCT06533267
Endoscopic Surgery vs. Intensity Modulated Radiotherapy for Stage I Nasopharyngeal Carcinoma. No drug interventions treatment Not Available recruiting NCT04830267
The Efficacy of Camrelizumab Plus Stereotactic Body Radiotherapy in R/M NPC treatment 2 recruiting NCT06095167
Induction Chemotherapy and Immunotherapy Combined Radiotherapy With or Without Concurrent Chemotherapy for Stage III-IVa NPC treatment 3 not_yet_recruiting NCT06129201
Development of a Machine Learning Model for Nasopharyngeal Carcinoma Screening Based on Tongue Imaging No drug interventions Not Available Not Available not_yet_recruiting NCT06389201
Pretreatment With HCQ Before Radiotherapy and Chemotherapy in Advanced NPC Patients treatment Not Available not_yet_recruiting NCT01865201
Effect of Edaravone on Radiation-induced Temporal Lobe Necrosis treatment 2 completed NCT03290001
The Influence of Anxiety and Depression on Survival in Nasopharyngeal Carcinoma Patients No drug interventions Not Available Not Available unknown_status NCT01479504
A Multicenter Trial Evaluating the Efficacy of Nedaplatin in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT05576272
A Phase II/III Trial to Evaluate the Efficacy and Safety of QL1706 in Patients With Nasopharyngeal Carcinoma treatment 2 / 3 active_not_recruiting NCT02505672
Vestibular Function After Chemoradiotherapy for Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT05780372
Reduced Volume of Neck Prophylactic Irradiation in Nasopharyngeal Carcinoma No drug interventions treatment 3 recruiting NCT03344068
Early and Whole Course Nutritional Support by Nutren® Optimum During IMRT for Nasopharyngeal Carcinoma No drug interventions treatment 2 / 3 unknown_status NCT04823468
Effect of Oral Nutritional Supplements on Body Weight Loss of Patients With Nasopharyngeal Carcinoma treatment Not Available recruiting NCT03429868
PET and MRI in Prognosis Prediction of NPC No drug interventions other Not Available completed NCT05304468
Reduced-dose Versus Standard Dose Radiotherapy for Nasopharyngeal Carcinomain treatment 3 recruiting NCT05447169
Epstein-Barr Virus Antibody and Epstein-Barr Virus DNA for Nasopharyngeal Carcinoma Screening No drug interventions Not Available Not Available recruiting NCT02476669
Serial Plasma EBV DNA for Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT00341146
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s) No drug interventions Not Available Not Available completed NCT04447612
Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 recruiting NCT06241612
Individualized Elective Neck Irradiation in NPC Patients No drug interventions treatment 3 recruiting NCT03557112
By Comparing TPF Induction Chemotherapy Combined With Nimotuzumab Concurrent Radiotherapy and Cisplatin Concurrent Radio-chemotherapy for Locally Advanced NPC treatment 2 unknown_status NCT04978012
Fluzoparib and Camrelizumab in Treating Patients With R/M NPC That Progressed After First-line Chemotherapy treatment 2 recruiting NCT02610010
Intensity-modulated Radiotherapy With or Without Concurrent Chemotherapy for Stage II Nasopharyngeal Carcinoma treatment 3 recruiting NCT04736810
A Study of Penpulimab Combination Therapy in Patients With Advanced Nasopharyngeal Carcinoma treatment 2 completed NCT03379610
A Prospective Study of Molecular Detection of Salvageable Early Recurrent Nasopharyngeal Carcinoma After Radiotherapy No drug interventions Not Available Not Available completed NCT04553510
Treatment of Bevacizumab Followed by Steroid in RN treatment 2 unknown_status NCT02907710
Endostar Combined With Concurrent Chemoradiotherapy for Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT03087695
Effect of the Plasma EBV DNA Change During Chemoradiotherapy in Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT05913414
Iron Isomaltide for Iron-deficiency Anemia Patients With Locally Advanced Nasopharyngeal Carcinoma treatment 2 recruiting NCT02434614
Induction Chemotherapy Followed by IMRT With or Without Concurrent Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT05724355
CDK4/6 Inhibitor Plus Camrelizumab for PD-1 Inhibitor Refractory R/M NPC treatment 2 recruiting NCT01817023
The Role of Concurrent Chemotherapy for Lower Risk Locally Advanced Nasopharyngeal Carcinoma(NPC) in the Era of IMRT treatment 3 unknown_status NCT01536223
Efficacy Study of Neoadjuvant Chemotherapy With Chemoradiation Therapy for Nasopharyngeal Carcinoma treatment 3 unknown_status NCT02301208
Weekly Cisplatin or Nedaplatin Concurrent With Intensity-modulated Radiation Therapy in Nasopharyngeal Carcinoma treatment 3 unknown_status NCT02582008
Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy prevention 0 terminated NCT02944708
Trial Evaluating Maintenance Chemotherapy for Metastatic Nasopharyngeal Carcinoma No drug interventions treatment 3 unknown_status NCT05772208
Intensified Treatments for Patients With Locally Advanced Nasopharyngeal Carcinoma With Detectable EBV DNA After One Cycle GP Regime Neoadjuvant Chemotherapy treatment 3 recruiting NCT03390738
Nivolumab as Treatment for Recurrent/Metastatic Nasopharyngeal Carcinoma After Failing 2 Lines or More Previous Chemotherapy treatment 2 withdrawn NCT01187238
The Value of Concurrent Chemoradiotherapy for Stage II Nasopharyngeal Carcinoma treatment 2 completed NCT05587543
Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma No drug interventions treatment 0 recruiting NCT01462903
A Study of Adoptive Immunotherapy With Autologous Tumor Infiltrating Lymphocytes in Solid Tumors No drug interventions treatment 1 unknown_status NCT04472403
Platinum Plus Low-dose Long-term Continuous Intravenous Infused 5-Fluorouracil in Metastatic Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT02584790
NBI to Detect Post-RT Mucosal Residual NPC No drug interventions diagnostic Not Available completed NCT03601390
Combining PET/CT and EBV DNA to Evaluate the Hazard of Progression in the Follow-up of Locally Advanced NPC No drug interventions Not Available Not Available completed NCT04350190
Apatinib Combined With PD-1 in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 2 completed NCT05431764
Whole-target Consolidation Therapy Under Systemic Therapy for Oligometastatic Nasopharyngeal Carcinoma treatment 2 recruiting NCT06259721
Anti-PD1 Monoclonal Antibody Combined With Nimotuzumab and Capecitabine in Patients With First-line Platinum-resistant Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 2 recruiting NCT03306121
TPF+CCRT vs.CCRT+PF in High Risk Nasopharyngeal Carcinoma No drug interventions treatment 3 active_not_recruiting NCT02633202
Concurrent Chemotherapy for the Intermediate Risk Nasopharyngeal Carcinoma In Intensity-modulated Radiotherapy Era treatment 3 unknown_status NCT03045484
Comparison of Oxycodone to Control Moderate or Severe Oral Mucositis Pain Induced by Chemoradiotherapy treatment Not Available unknown_status NCT04073784
Gemcitabine Combined With Apatinib and Toripalimab in Recurrent or Metastatic Nasopharyngeal Carcinoma. treatment 1 unknown_status NCT04028479
The Registry of Oncology Outcomes Associated With Testing and Treatment No drug interventions Not Available Not Available recruiting NCT02801487
Trial Evaluating Carbon Ion Radiotherapy With Concurrent Chemotherapy for Locally Recurrent Nasopharyngeal Carcinoma treatment 1 / 2 terminated NCT01884987
Treatment of Cerebral Radiation Necrosis With GM1, a Prospective Study Not Available Not Available unknown_status NCT02460887
The Role of Induction Gemcitabine and Cisplatin in Locoregionally Advanced Nasopharyngeal Carcinoma in the Era of IMRT treatment 3 active_not_recruiting NCT06516133
Online Adaptive Radiotherapy for Nasopharyngeal Carcinoma No drug interventions treatment 3 recruiting NCT06523933
Distribution of Bacteria in OME After Radiotherapy For NPC. No drug interventions Not Available Not Available active_not_recruiting NCT03025854
Prospective Study for Prognostic Biomarkers of Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT03701451
Demethylated Drug in the Treatment of Nasopharyngeal Carcinoma treatment 1 / 2 unknown_status NCT00188253
Positron Emission Tomography Scanning and Epstein-Barr Virus DNA Levels in the Staging and Follow-up of Nasopharyngeal Carcinoma. No drug interventions Not Available Not Available completed NCT02575547
Effect of Chemoradiotherapy on Nutritional Status in Advanced NPC Patients Not Available Not Available completed NCT01265147
Intensity-modulated Radiation Therapy Combined With Cisplatin or Nedaplatin Chemotherapy in Nasopharyngeal Carcinoma treatment 2 unknown_status NCT04094545
Intestinal Flora Sequencing for Nasopharyngeal Carcinoma No drug interventions Not Available Not Available completed NCT04974398
A Study of Penpulimab (AK105) in the First-line Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 3 recruiting NCT03752398
A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) treatment 1 completed NCT05415098
Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas No drug interventions treatment 1 recruiting NCT03267498
Nivolumab + Chemoradiation in Stage II-IVB Nasopharyngeal Carcinoma (NPC) treatment 2 active_not_recruiting NCT04813705
18F-FDG PET/CT Guided Reduced-dose Radiotherapy for Nasopharyngeal Carcinoma No drug interventions treatment 2 recruiting NCT03048305
Prospective Study for Molecular Biomarkers of Normal Nasopharyngeal Tissue No drug interventions Not Available Not Available unknown_status NCT00697905
Combination of Gemcitabine and Carboplatin in Metastatic or Recurrent Nasopharyngeal Carcinoma treatment 2 completed NCT03648697
EBV-TCR-T（YT-E001）for Patients With EBV-positive Recurrent or Metastatic NPC treatment 2 unknown_status NCT05433597
A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC treatment 2 / 3 not_yet_recruiting NCT00817583
Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma (NPC) treatment 2 unknown_status NCT05884983
Screening Effect of Dual-energy CT Combined With Nasopharyngeal Endoscopy for Screening Nasopharyngeal Carcinoma No drug interventions Not Available Not Available recruiting NCT05979961
Phase III Trial of Concurrent Chemotherapy Alone in Patients With Low-risk Nasopharyngeal Carcinoma treatment 3 recruiting NCT06093061
Tislelizumab and Metronomic Capecitabine as Maintenance in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma treatment 2 recruiting NCT04220528
Radical Radiotherapy and Chemotherapy Combined With Maintenance Chemotherapy in the Treatment of Stage N3 NPC treatment 2 unknown_status NCT02958111
Single-agent Capecitabine as Adjuvant Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT02287311
Most Closely Matched 3rd Party Rapidly Generated LMP, BARF1 And EBNA1 Specific CTL, EBV-Positive Lymphoma (MABEL) treatment 1 recruiting NCT02022293
Atorvastatin in Preventing Nasopharyngeal Carcinoma Patients Receiving Radiotherapy From Carotid Stenosis prevention 2 suspended NCT05341193
PD-1 Blockade and Bevacizumab Replace Cisplatin in Locoregionally Advanced Nasopharyngeal Carcinoma treatment 1 / 2 not_yet_recruiting NCT04548271
Camrelizumab Combined With Apatinib in Patients With PD-1 Antagonists Resistant Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 2 unknown_status NCT06026878
GNT Induction Treatment in Locally Advanced NPC treatment 3 recruiting NCT05099978
Asian Multicenter Prospective Study of ctDNA Sequencing No drug interventions Not Available Not Available active_not_recruiting NCT04061278
A Multicenter, Prospective, Phase III Randomized Controlled Clinical Study for the Treatment of N2-3 Nasopharyngeal Carcinoma Patients No drug interventions treatment 3 unknown_status NCT02569788
Trail Evaluating Carbon Ion Radiotherapy for Locally Recurrent Nasopharyngeal Carcinoma No drug interventions treatment 1 / 2 terminated NCT01086488
Foscan®-Mediated Photodynamic Therapy Versus Brachytherapy in Patients With Nasopharyngeal Carcinoma treatment 2 unknown_status NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors treatment 1 completed NCT04586088
Apatinib and Camrelizumab in Recurrent or Metastatic Nasopharyngeal Carcinoma With First-line Treatment Failure treatment 2 active_not_recruiting NCT04992988
Concurrent Chemoradiotherapy With Toripalimab for Local-regional Recurrent Nasopharyngeal Carcinoma: a Prospective, Single-arm, Phase II Trial treatment 2 unknown_status NCT02289807
Concurrent Chemotherapy in Intermediate Risk Patients Treated With Intensity-modulated Radiotherapy treatment Not Available withdrawn NCT02642107
Individualized Elective Neck Irradiation Based on MRI in NPC Patients No drug interventions treatment 3 completed NCT03346109
To Study the Feasibility and Quality of Life of Medial Group Retropharyngeal Node Sparing in Nasopharyngeal Carcinoma No drug interventions treatment Not Available unknown_status NCT04227509
Consolidation Pembrolizumab After Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma treatment 2 recruiting NCT03707509
Phase III Study of Camrelizumab in Combination With Chemotherapy in Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 3 unknown_status NCT02293356
Phase IV Clinical Trial of Nimotuzumab in the Treatment of Nasopharyngeal Carcinoma treatment 4 unknown_status NCT04778956
Toripalimab Plus Surgery vs Surgery Alone for Resectable Recurrent Nasopharyngeal Carcinoma treatment 3 recruiting NCT02610556
Concurrent Docetaxel Plus Cisplatin or Cisplatin Alone With IMRT in High Risk Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05898256
Cadonilimab in the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 1 / 2 not_yet_recruiting NCT05519956
Elective Level Ib Irradiation in Nasopharyngeal Carcinoma Patients Based on the International Guidelines No drug interventions treatment 3 not_yet_recruiting NCT01447056
Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases No drug interventions treatment 1 completed NCT04398056
Chemotherapy Plus Subsequent Loco-regional Radiotherapy Combined With Toripalimab in the De Novo Metastatic Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05448885
Neoadjuvant and Adjuvant Tislelizumab for Nasopharyngeal Carcinoma treatment 2 recruiting NCT01534585
Safety and Efficacy Study of Icotinib With Intensity-modulated Radiotherapy in Nasopharyngeal Carcinoma treatment 1 / 2 completed NCT04995185
18F-FMISO PET Guided Dose Escalation in Nasopharyngeal Carcinoma - a Feasibility and Planning Study No drug interventions diagnostic Not Available completed NCT05229315
PD-1 Combined With Intensity Modulated Radiation Therapy in the Treatment of Intermediate-risk Nasopharyngeal Carcinoma treatment 2 recruiting NCT03366415
Sequential or Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced NPC treatment 3 recruiting NCT05177237
Endostar Combined With Corticosteroid for Treatment of Radiation-induced Brain Necrosis in Nasopharyngeal Carcinoma treatment 2 recruiting NCT02915432
The Study to Evaluate Toripalimab (JS001) in Patients With Advanced GC, ESCC, NPC, HNSCC treatment 1 / 2 unknown_status NCT03568032
Radiation-associated Carotid Artery Disease in Patients With Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT03915132
Nimotuzumab Combined With VMAT in Elderly Patients With Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05211232
Neoadjuvant and Adjuvant Tislelizumab for Nasopharyngeal Carcinoma treatment 3 active_not_recruiting NCT05232552
Study of Anlotinib With Chemoradiation for Patients With Locally Advanced Nasopharyngeal Carcinoma treatment 2 recruiting NCT05790200
Cadonilimab (AK104) in the Treatment of Nasopharyngeal Carcinoma health_services_research 2 recruiting NCT06268600
The Protection of Thyroid Function in IMRT for Nasopharyngeal Carcinoma No drug interventions treatment Not Available recruiting NCT01326559
Study to Evaluate Induction Chemotherapy Using Docetaxel, Cisplatin and Fluorouracil in Concurrence With Intensity-modulated Radiotherapy for Local Recurrent Nasopharyngeal Carcinoma (NPC) treatment 2 completed NCT01403259
SOX as Salvage Treatment in Nasopharyngeal Carcinoma treatment 2 terminated NCT05514275
Radiotherapy Combined With Endostatin and Capecitabine for NPC treatment 2 recruiting NCT05527470
Induction Chemotherapy Followed by IMRT or Concurrent Chemoradiotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 recruiting NCT04907370
PD-1 Blockade Combined With De-intensification Radical Chemoradiotherapy in Nasopharyngeal Carcinoma treatment 3 active_not_recruiting NCT03130270
Maintenance Treatment of Apatinib in Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05340270
PD-1 Inhibitor Plus GP as Neoadjuvant Therapy for Locoregionally Advanced Nasopharyngeal Carcinoma No drug interventions treatment 2 not_yet_recruiting NCT04282070
SHR-1701 in Patients With Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 1 unknown_status NCT04917770
The Efficacy and Safety of Sintilimab in Combination With Multimodal Radiotherapy in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 2 unknown_status NCT01449942
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma No drug interventions treatment 1 / 2 completed NCT03670342
Pilot Study of Somatostatin Receptor Imaging in Nasopharyngeal Cancer No drug interventions Not Available Not Available completed NCT02562599
Chemoradiotherapy for Patients With Locally Advanced Nasopharyngeal Carcinoma Using Raltitrexed-Cisplatin treatment 2 completed NCT02063399
Prospective Nasopharyngeal Carcinoma Screening Using Plasma Epstein-Barr Virus DNA Analysis No drug interventions Not Available Not Available active_not_recruiting NCT05854849
Gemcitabine and Camrelizumab Plus Apatinib Versus Cisplatin in First-line Treatment of RM-NPC treatment 3 recruiting NCT06367049
Methylation-specific PCR Test for Early Screening and Early Diagnosis of Nasopharyngeal Carcinoma No drug interventions Not Available Not Available completed NCT05949749
A Retrospective Study Reveals the Relationship Between gp42-IgG Epitopes and EBV-associated NPC No drug interventions Not Available Not Available recruiting NCT04810936
Early Nutritional Intervention in NPC Patients Undergoing Concurrent Chemoradiotherapy No drug interventions supportive_care Not Available unknown_status NCT04453813
Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma treatment 3 recruiting NCT03598218
Hypofractionated Versus Conventionally Fractionated Radiotherapy for Initial Distant Metastases Nasopharyngeal Carcinoma No drug interventions treatment Not Available completed NCT00677118
Adjuvant Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT01712919
Chemoradiation Plus Weekly c225 Against Locoregionally Advanced Nasopharyngeal Carcinoma (NPC) treatment 1 / 2 completed NCT02460419
Maintenance Capecitabine Plus Best Supportive Care Versus Best Supportive Care for Metastatic Nasopharyngeal Carcinoma treatment 3 completed NCT03657017
PET/MR in Locally Advanced Nasopharyngeal Carcinoma No drug interventions diagnostic Not Available recruiting NCT05092217
Tirelizumab Plus Surgery vs Surgery Alone for Recurrent Nasopharyngeal Carcinoma No drug interventions treatment 2 not_yet_recruiting NCT02058017
OPB-51602 in Locally Advanced Nasopharyngeal Carcinoma Prior to Definitive Chemoradiotherapy No drug interventions treatment 1 terminated NCT04272034
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors No drug interventions treatment 1 active_not_recruiting NCT04223024
Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma prevention 2 active_not_recruiting NCT02237924
Endostar Combined With Intensity-modulated Radiotherapy Compare With Chemoradiation for Nasopharyngeal Carcinoma treatment 2 completed NCT03809624
Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer treatment 1 active_not_recruiting NCT03981224
The Value of Post-radiation Detectable Plasma EBV DNA in High-risk Nasopharyngeal Carcinoma Patients No drug interventions Not Available Not Available completed NCT03121716
A Study to Evaluate the Safety and Efficacy of SHR-1210, Gemcitabine and Cis-platinum by R/M NPC Subjects treatment 1 completed NCT00816816
Phase Ⅱ Study of Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for Stage ⅣAB Nasopharyngeal Carcinoma treatment 2 unknown_status NCT03925896
Phase I Trial of LMP2 Antigen-specific TCR T-cell Therapy for Recurrent and Metastatic NPC Patients No drug interventions treatment 1 unknown_status NCT03906058
Anlotinib in Recurrent or Metastatic Nasopharyngeal Carcinoma Patients After Failure of no Less Than Second-line Therapy treatment 2 completed NCT03025958
Radiation Plus Concurrent Nimotuzumab in Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 completed NCT00817258
Study of Concurrent Chemotherapy and Radiotherapy for Stage II Nasopharyngeal Carcinoma treatment 2 unknown_status NCT03240835
The Function of PA, RBP and TRSF in Malnutrition Detecting and Nutritional Status Monitoring for NPC Patients Not Available Not Available active_not_recruiting NCT04593186
Magnifying NBI for Occult NPC No drug interventions screening Not Available recruiting NCT03848286
KL-A167 Injection in Recurrent or Metastatic Nasopharyngeal Carcinoma No drug interventions treatment 2 completed NCT01612286
Endostar Combination With Chemotherapy for the Metastatic Nasopharyngeal Carcinoma treatment 2 unknown_status NCT06323239
SBRT and LDRT Combined With PD-1 Antibody and Chemotherapy in r/m Nasopharyngeal Carcinoma treatment 2 recruiting NCT03097939
Phase 2 Trial of Ipilimumab and Nivolumab in Nasopharyngeal Carcinoma treatment 2 recruiting NCT01271439
Study of Chemoradiotherapy Combined With Cetuximab in Nasopharyngeal Carcinoma treatment 2 completed NCT04405622
Toripalimab and Gemcitabine in Recurrent or Metastatic Nasopharyngeal Carcinoma. treatment 2 active_not_recruiting NCT05771025
Effect of Hepatectomy on the Prognosis of Patients With Nasopharyngeal Carcinoma Liver Metastases No drug interventions treatment Not Available recruiting NCT02940925
TPC vs PF as Induction Chemotherapy Combined With CCRT for Stage IVa-b Nasopharyngeal Carcinoma No drug interventions treatment 3 completed NCT03047525
Study of DC-CTL Combined With CIK for Advanced Solid Tumor No drug interventions treatment 1 / 2 unknown_status NCT03668730
Reduced-dose Radiotherapy for Low-risk Stage III Patients With Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05981157
Anrotinib and Tirelizumab in First-line Treatment of RM-NPC No drug interventions treatment 2 recruiting NCT05037357
Verification of Harmonization of Plasma Epstein-Barr Virus DNA Measurements No drug interventions Not Available Not Available unknown_status NCT00515957
Study of LMP1- and LMP2- Specific Cytotoxic T-Lymphocytes (CTL) No drug interventions treatment 1 withdrawn NCT05813626
Neoadjuvant Chemotherapy Plus Toripalimab in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 recruiting NCT04447326
Toripalimab, Endostar Combined With Radiotherapy and Chemotherapy for Nasopharyngeal Carcinoma treatment 2 not_yet_recruiting NCT02597426
Nasopharyngeal Carcinoma Post IMRT No drug interventions Not Available Not Available active_not_recruiting NCT06370026
KSD-101 Therapy for Standard Treatment Failed EBV-associated NPC: an Exploratory Clinical Trial No drug interventions treatment 0 not_yet_recruiting NCT04387266
To Evaluate the Efficacy and Feasibility of Modified Reduce-volume Target IMRT in the Treatment of Patients With Non-metastatic NPC No drug interventions Not Available Not Available completed NCT03047265
Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 active_not_recruiting NCT04436965
Effect of Standard Nutrition Therapy on Nutritional Status and Prognosis in Locoregionally Advanced Nasopharyngeal Carcinoma Patients With Malnutrition treatment 3 recruiting NCT04394065
uEXPLORER Total-body PET/CT in Nasopharyngeal Carcinoma No drug interventions Not Available Not Available completed NCT05587374
Cadonilimab (PD-1/CTLA-4 Bi-specific Antibody) and Chemoradiotherapy in Locoregionally-advanced Nasopharyngeal Carcinoma treatment 3 recruiting NCT03876574
Hepatic Artery Infusion Pump for NPC Liver Metastases treatment 1 completed NCT03810274
3DV+TPS Software Outlines the Radiotherapy of Nasopharyngeal Carcinoma No drug interventions Not Available Not Available completed NCT06486220
PFLL Combined With PD-1 Antibody With or Without FMT for Oligometastatic NPC,a Phase III ,Open, Randomized Clinical Trial. No drug interventions treatment 3 not_yet_recruiting NCT04557020
Adding PD-1 Inhibitor to Neoadjuvant and Adjuvant for NPC treatment 3 recruiting NCT03855020
Serial Epstein-Barr Virus DNA Surveillance in Nasopharyngeal Carcinoma Patients No drug interventions Not Available Not Available active_not_recruiting NCT04351282
SBRT for Oligo-metastatic Lesions After Systemic Treatment of Primary Metastatic Nasopharyngeal Carcinoma No drug interventions treatment Not Available not_yet_recruiting NCT03202173
The Diagnosis of NPC Using the Probe-based Confocal Laser Endomicroscopy No drug interventions diagnostic Not Available unknown_status NCT06239727
Reduced-dose Radiotherapy for Stage III Nasopharyngeal Carcinoma Based on the Treatment Response treatment 3 recruiting NCT00705627
A Multicenter Trial Comparing Multi-course Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma No drug interventions treatment 3 unknown_status NCT05292027
Neoadjuvant Chemotherapy and Low-dose Radiotherapy Sequential Concurrent Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma No drug interventions treatment Not Available unknown_status NCT03647527
Predictor Analysis of Acute Radiation Oral Mucositis in NPC Patients Treated With IMRT/TOMO Combined Chemotherapy No drug interventions Not Available Not Available unknown_status NCT04384627
Reducing Target Volumes in NPC Treated With Induction Chemotherapy Followed by Concurrent Chemoradiotherapy No drug interventions treatment 3 active_not_recruiting NCT05869227
Maintenance Therapy With Toripalimab Combined With Capecitabine/Placebo for Recurrent and Metastatic Nasopharyngeal Carcinoma No drug interventions treatment 3 recruiting NCT01230476
Induction and Concurrent Chemoradiotherapy With Cetuximab for Patients With Locally Advanced Nasopharyngeal Carcinoma treatment 2 terminated NCT02111460
Chemotherapy Combined With Radiotherapy vs Chemotherapy Alone for Distant Metastatic Nasopharyngeal Carcinoma No drug interventions treatment 3 unknown_status NCT05290194
Radiotherapy Combined With PD-1 Monoclonal Antibody and Capecitabine in the Treatment of Nasopharyngeal Carcinoma treatment 2 recruiting NCT06244394
Retrospective Study on the Prediction of Radiation-induced Brain Injury in Patients With Nasopharyngeal Carcinoma No drug interventions Not Available Not Available completed NCT02012062
Concurrent Nimotuzumab Versus Cisplatin With Radiotherapy for Locoregionally Advanced NPC treatment 3 completed NCT04929080
The Safety and Efficacy of Multiple-dose of JS004 in Subject With HNC treatment 1 / 2 completed NCT03942380
Cell-free Tumor DNA in Head and Neck Cancer Patients No drug interventions diagnostic Not Available recruiting NCT06383780
Tislelizumab in Combination With GP or TPC Regimen for the Treatment of Nasopharyngeal Carcinoma With Bone Metastasis. treatment 3 recruiting NCT05563480
TQB2618 Injection Combined With Penpulimab Injection in the Treatment of Patients With Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 2 recruiting NCT03398980
Late Sequelae of Childhood and Adolescent Nasopharyngeal Carcinoma Survivors After Radiotherapy No drug interventions Not Available Not Available completed NCT05626829
Tranilast as a Radiosensitizer in Reradiation of Nasopharyngeal Carcinoma treatment 2 recruiting NCT05544929
A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers treatment 1 recruiting NCT02878889
A Phase II Trial of S-1 as Maintenance Treatment After Gemcitabine Plus Cisplatin Regimen Chemotherapy in Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma. No drug interventions treatment 2 unknown_status NCT06349889
Adebrelimab and Chemoradiotherapy in High-risk Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 not_yet_recruiting NCT05147844
Toripalimab Combined With Radiotherapy in the Treatment of Oligometastatic Nasopharyngeal Carcinoma treatment 2 recruiting NCT02500940
Comparison the Effects of Different Neoadjuvant Chemotherapy Regimen on Acute Toxicity, Tumor Response, and Survival in Patients With Advanced Nasopharyngeal Carcinoma treatment 3 unknown_status NCT03769467
Tabelecleucel in Combination With Pembrolizumab in Subjects With Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC) treatment 1 / 2 terminated NCT05020067
Impact on Xerostomia for Nasopharyngeal Carcinoma Patients Treated With or Without Superficial Parotid Lobe-sparing Intensity-modulated Radiotherapy No drug interventions prevention 2 completed NCT03353467
Endoscopic Nasopharyngectomy for Newly Diagnosed Stage I Nasopharyngeal Carcinoma Patients No drug interventions treatment Not Available recruiting NCT06032767
Prospective Observational Study to Predict Severe Oral Mucositis Associated With Chemoradiotherapy in Nasopharyngeal Carcinoma Based on Deep Learning No drug interventions Not Available Not Available recruiting NCT03866967
A Study of Anti-PD-1 AK105 in Patients With Metastatic Nasopharyngeal Carcinoma treatment 2 active_not_recruiting NCT06177301
Tislelizumab Plus GX Versus Tislelizumab Plus GP in the Treatment of R/M NPC treatment 3 recruiting NCT00592501
Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma treatment 2 completed NCT01237704
Dysphagia Rehabilitation for Nasopharyngeal Carcinoma Patients Post Radiotherapy No drug interventions treatment Not Available unknown_status NCT02089204
Hypoxia Imaging -Guided Radiotherapy of Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT05294172
KL-A167 Injection Combined With Cisplatin and Gemcitabine vs Placebo Combined With Cisplatin and Gemcitabine in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma treatment 3 active_not_recruiting NCT05162872
Niraparib And Sintilimab In Recurrent/Metastatic Nasopharyngeal Carcinoma treatment 2 unknown_status NCT05563272
89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors diagnostic 2 recruiting NCT05877872
Reduced-target Resection After Induction Chemotherapy in Resectable Recurrent Nasopharyngeal Carcinoma No drug interventions treatment 3 recruiting NCT05524168
SBRT Combined With PD-1 Antibody and Chemotherapy in Oligometastatic Nasopharyngeal Carcinoma treatment 2 recruiting NCT05616468
BGT007 Cell Treatment of Nasopharyngeal Carcinoma treatment 0 recruiting NCT04421469
Triprilimab(JS001) and Chemotherapy Combined With Local Treatment for Multiple Metastatic NPC treatment 2 unknown_status NCT04544969
Detecting Chemosensitivity and Predicting Treatmemt Efficacy With CTCs in mNPC Not Available Not Available recruiting NCT03849469
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors treatment 1 completed NCT05330169
Hearing Impairment of Nasopharyngeal Carcinoma No drug interventions Not Available Not Available completed NCT05834712
Patients With Stage III-IVa Nasopharyngeal Carcinoma With or Without a Mobile Medical Platform Full-course Nutritional Intervention No drug interventions prevention Not Available recruiting NCT05627310
Development and Validation of a Deep Learning System for Nasopharyngeal Carcinoma Using Endoscopic Images No drug interventions Not Available Not Available recruiting NCT02854410
Dietary Nitrate on Salivary Flow for Nasopharyngeal Carcinoma Patients No drug interventions prevention Not Available unknown_status NCT06455410
GP Plus Adebrelimab Versus GP Neoadjuvant Chemotherapy for Nasopharyngeal Carcinoma treatment 2 recruiting NCT05893810
Bacterial Decolonization to Prevent Radiation-induced Oral Mucositis prevention 3 recruiting NCT00431210
Epstein-Barr Virus-Specific Immunotherapy for Nasopharyngeal Carcinoma No drug interventions treatment 1 completed NCT00155181
Molecular Mechanism of Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT00535795
Phase III: Assess Conventional RT w/ Conventional Plus Accelerated Boost RT in the Treatment of Nasopharyngeal CA No drug interventions treatment 3 completed NCT00634595
Trial of E10A in Head and Neck Cancer treatment 2 unknown_status NCT01821495
Study of DC-CIK to Treat NPC No drug interventions treatment 2 unknown_status NCT02795195
Trail Evaluating Carbon Ion Radiotherapy (3 GyE Per Fraction) for Locally Recurrent Nasopharyngeal Carcinoma No drug interventions treatment 1 / 2 unknown_status NCT03389295
Reduced Target Delineation and Radiation Doses Chemoradiotherapy for Patients With Locoregionally Advanced Nasopharyngeal Carcinoma No drug interventions treatment 2 completed NCT04944914
Camrelizumab Plus Stereotactic Body Radiotherapy vs Camrelizumab Alone For Oligometastatic Nasopharyngeal Carcinoma treatment 3 recruiting NCT06307314
Plasma SAA1 Levels in Predicting Response to Radiotherapy-induced Oral Mucositis No drug interventions Not Available Not Available recruiting NCT04517214
Comparing Chemotherapy With/Without Toripalimab For Primary Metastatic Nasopharyngeal Carcinoma treatment 2 recruiting NCT05520814
PD-1 Inhibitors Plus Chemoradiotherapy for Metastatic Nasopharyngeal Carcinoma: an Open-label Single-arm, Phase II Trial No drug interventions treatment 2 active_not_recruiting NCT00816855
Phase Ⅱ Study of Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for Stage Ⅲ Nasopharyngeal Carcinoma treatment 2 unknown_status NCT04534855
A Phase II Clinical Study of Treprilimab in the Treatment of Recurrent Nasopharyngeal Carcinoma After Re-irradiation No drug interventions treatment 2 not_yet_recruiting NCT03682055
Phase 1/2a Study of VK-2019 in Patients With Epstein-Barr Virus (EBV)-Positive Nasopharyngeal Carcinoma (NPC) No drug interventions treatment 1 / 2 terminated NCT06277050
Maintenance Therapy With Toripalimab and Capecitabine Versus Capecitabine Alone in High-risk Nasopharyngeal Carcinoma treatment 3 recruiting NCT04522050
Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma treatment 1 recruiting NCT06313450
De-escalated Radiotherapy for Primary Tumor After Neoadjuvant Therapy With Toripalimab Plus Chemotherapy for Nasopharyngeal Carcinoma No drug interventions treatment Not Available recruiting NCT05146050
Olfactory Change After Chemo-radiotherapy for Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT03973723
Plasma EBV DNA Monitoring in Post-treatment NPC Patients No drug interventions Not Available Not Available completed NCT05741008
Clincal Study of Reduced Target Radiotherapy in Nasopharyngeal Carcinoma No drug interventions treatment Not Available recruiting NCT00778908
Late-Course Accelerated Hyperfractionated IMRT for Locoregionally Advanced Nasopharyngeal Carcinoma treatment 2 / 3 completed NCT00212108
A Study Of Nasopharyngeal Carcinoma (NPC) Treated With Celecoxib And ZD1839 treatment 1 / 2 completed NCT03837808
Radiotherapy Plus Concurrent Nimotuzumab or Cisplatin in Stage II-III Nasopharyngeal Carcinoma treatment 3 recruiting NCT03854838
IMRT Combined With Toripalimab in Unresectable Locally Recurrent Nasopharyngeal Carcinoma. treatment 2 unknown_status NCT04108338
Prospective Comparisons of Clinical Trial and Real-world Outcomes in Nasopharyngeal Carcinoma No drug interventions Not Available Not Available completed NCT04014738
The Prognostic Value of Human Papilloma Virus in Nasopharyngeal Carcinoma No drug interventions Not Available Not Available unknown_status NCT01614938
Induction Chemotherapy Followed by Concurrent Radiation With Cetuximab or Cisplatin in Locally Advanced Nasopharyngeal Cancer treatment 2 unknown_status NCT04284332
Phase II Prospective Study of Bintrafusp Alfa in Previously Treated Patients With Recurrent and Metastatic (R/M) Non-keratinizing Nasopharyngeal Carcinoma (NPC) treatment 2 not_yet_recruiting NCT04215978
Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors treatment 2 active_not_recruiting NCT06611150
Concurrent Nab-paclitaxel with Intensity-modulated Radiation Therapy in Patients with Stage III-IVa Nasopharyngeal Carcinoma treatment 1 recruiting NCT06612697
Long-term Outcomes of Early-stage Nasopharyngeal Carcinoma Patients Treated with Radiotherapy Alone No drug interventions Not Available Not Available active_not_recruiting NCT02822495
Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia or Malignancies Not Available Not Available no_longer_available NCT04538547
Randomized Trial to Evaluate Accelerated Radiotherapy in Locally Advanced Carcinoma of Nasopharynx No drug interventions treatment Not Available unknown_status NCT04945421
IBI310 in Combination With Siltilimab in Subjects With Anti-PD-1/PD-L1 Resistance R/M NPC treatment 1 completed NCT01744587
Epstein-Barr Virus Reactivation and the Effect of EGCG on Virus Reactivation in Remission Patients No drug interventions prevention Not Available unknown_status NCT05983432
Study to Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors No drug interventions treatment 1 recruiting NCT03919552
Cisplatin-based and Carboplatin-based Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma treatment 3 recruiting NCT03352778
IMRT vs 2DRT for NPC Patients No drug interventions Not Available Not Available completed NCT03734809
NEO-SPACE Trial: Pembrolizumab and Chemoradiation in Nasopharyngeal Cancer treatment 2 active_not_recruiting NCT03158324
Phase IIa Dose-Expansion and Biomarker Study of OPB-111077 treatment 2 unknown_status