Hyperphosphataemia (DBCOND0015896)

Identifiers

Synonyms
Hyperphosphatemia / Hyperphosphatemia (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Aluminum chloride
Indicated for the control of minor hemorrhage during dental restorative procedures. Indicated to reduce underarm perspiration.
Aluminum hydroxide
An antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
No drug targets
Calcium acetate
A phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism.
Calcium carbonate
An ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
No drug targets
Colestilan chloride
Colestilan is an ingredient in the EMA-withdrawn product BindRen.
No drug targets
Ferric cation
An iron supplement indicated in the treatment of iron deficiency anemia.
Iron sucrose
An compound used as a source of iron in patients with iron deficiency anemia associated with chronic kidney disease (CKD).
No drug targets
Lanthanum carbonate
A phosphate binder indicated for the reduction of serum phosphate in patients with end-stage renal disease.
Sevelamer
A phosphate binder used to treat hyperphosphatemia.
Tetraferric tricitrate decahydrate
A phosphate binder used to control serum phosphorus levels or as an iron supplement.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01857024
Post Authorisation Safety Study of Renvela® in Chronic Kidney Disease Patients Not on Dialysis With HyperphosphataemiaNot AvailableNot Availablecompleted
NCT01424787
Non-interventional Study to Evaluate the Ease of Reaching Individual Goals in Serum Phosphorus (Steering)No drug interventionsNot AvailableNot Availablecompleted
NCT02151643
Study to Evaluate the Efficacy and Safety of PT20 in Subjects With Hyperphosphataemia and Dialysis Dependent Chronic Kidney Diseasetreatment2completed
NCT05764590
A Study to Evaluate Safety and Efficacy of AP-306 in Hyperphosphatemia Patientstreatment2completed
NCT01850602
A Phase III Study of PA21 in Hemodialysis Patients With Hyperphosphatemiatreatment3completed
NCT01200784
Nicotinamide in Hemodialysis Patients With Hyperphosphatemiatreatment2completed
NCT02836184
Nicotinic Acid in Hemodialysis Patients With Hyperphosphatemiatreatment4unknown_status
NCT02684643
Study of Individualized Therapy on Hyperphosphatemia in Maintenance Hemodialysis PatientsNo drug interventionstreatmentNot Availablecompleted
NCT02940743
Behavioral Management of Phosphorus in Hemodialysis PatientsNo drug interventionstreatmentNot Availablecompleted
NCT03824587
Study to Evaluate the Efficacy of Tenapanor as Adjunctive Therapy to Phosphate Binder Therapytreatment2 / 3completed
NCT02965053
A Phase1 Study to Explore the Safety of EOS789 in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysistreatment1completed
NCT03861247
Individualized Treatment of Hyperphosphatemia in Maintenance Hemodialysis PatientsNo drug interventionstreatment3completed
NCT04922645
Auryxia (Ferric Citrate) Therapy for In-Center and Home Dialysis Participantstreatment4completed
NCT03864445
Phosphate Binder-combination Study of KHK7791 in Hyperphosphatemia PatientsNo drug interventionstreatment2completed
NCT04766398
Phosphate Binder-combination Study of KHK7791 in Hyperphosphatemia Patients on HemodialysisNo drug interventionstreatment3completed
NCT01329497
The Effect of Systemic Dietary Instruction on Management of Plasma Phosphorus Levels in Peritoneal Dialysis (PD) PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT04549597
Study to Evaluate the Use of Tenapanor as Core Therapy in the Treatment of Hyperphosphatemiatreatment4completed
NCT02755961
Efficacy of Dietary Education and Education on Phosphate Binder Use in Hemodialysis PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT01039428
A Study of HS219 in Chronic Kidney Disease Patients on Hemodialysis With HyperphosphatemiaNo drug interventionstreatment2completed
NCT01187628
Long-term Study in Chronic Kidney Disease (Extension From Study 14817)treatment3completed
NCT03001011
Evaluation of Renvela in Patients With Chronic Kidney Disease Not On Dialysis And Hyperphosphatemia In Chinatreatment3completed
NCT03305471
DS2330b Alone and With Sevelamer in Patients on Chronic Hemodialysistreatment1completed
NCT01252771
Phosphate Kinetic Modeling 2No drug interventionstreatment4completed
NCT00211978
EPIC(Effect of PhosLo on Phosphorus Levels in Chronic Kidney Disease)treatment3completed
NCT01319578
PD Study to Assess Phosphate Binding Characteristics of K2CG Chewing GumNo drug interventionsNot AvailableNot Availablecompleted
NCT05577507
Efficacy and Safety of Cholestyramine in the Management of Hyperphosphatemia in Adult Hemodialysis Patientstreatment4completed
NCT03831607
A Phosphate Binder Switch Study of KHK7791 in Hyperphosphatemia Patients on HDtreatment2completed
NCT03202407
Hyperphosphatemia in Children With Chronic Kidney Diseasetreatment3unknown_status
NCT01742585
A Phase 3 Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia Not on Dialysistreatment3completed
NCT04579315
Long-term Effects of the New Nordic Renal Diet in Patients With Moderate Chronic Kidney DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT00767637
Long-term Treatment on BAY77-1931 (Lanthanum Carbonate) to Measure Lanthanum Concentrations in Bonetreatment2completed
NCT00364000
Arterial Stiffness and Calcifications in Haemodialysis Patients on Sevelamer or Calcium AcetatetreatmentNot Availablewithdrawn
NCT00583570
Phosphorus Improvement Pilot StudyNo drug interventionshealth_services_researchNot Availablecompleted
NCT00892749
Long-term Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysistreatment3completed
NCT00506441
A Phase 3, Randomized, Double Blind, Placebo-Controlled, Multi-Center, Withdrawal Study of MCI-196 in CKD on Dialysis With Hyperphosphatemiatreatment3completed
NCT00681941
An Open Label Dose Titration of Sevelamer Carbonate Tabs 3 Times a Day in Hyperphosphatemic CKD Patients Not On Dialysistreatment3completed
NCT01814917
Long-term Extension Study of MCI-196treatment3terminated
NCT06186934
Post Marketing Surveillance Study to Observe Safety and Effectiveness of NEPHOXIL ® in S. Korea PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02081534
Dose Finding Study to Treat High Phosphate Levels in the Blood.treatment2completed
NCT02237534
Lanthanum Versus Calcium Carbonate for Vascular Abnormalities in Patients With CKD and Hyperphosphatemiatreatment4unknown_status
NCT03864458
Dose-finding Study of KHK7791 in Hyperphosphatemia PatientsNo drug interventionstreatment2completed
NCT00542386
A Study of MCI-196 in Chronic Kidney Disease Subjects on Dialysis With Hyperphosphatemia and Dyslipidaemiatreatment3completed
NCT01074125
A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Diseasetreatment3completed
NCT03427125
A Phase 3 Study of Tenapanor to Treat Hyperphosphatemia in ESRD Patients on Dialysistreatment3completed
NCT00660530
Chewed vs. Crushed Lanthanum Carbonate in Hemodialysis Patientstreatment2completed
NCT03409757
Velphoro and Impact on the Oral Cavity and Gut MicrobiomeNot AvailableNot Availableterminated
NCT01574326
An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney Diseasetreatment2completed
NCT02492620
Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5Dtreatment3completed
NCT00742820
Bioequivalence Study Comparing Calcium Acetate Oral Solution Versus Calcium Acetate Gelcaps in Healthy Volunteerstreatment1completed
NCT03988920
A Long-Term Study of Tenapanor Alone or in Combination With Sevelamer in Patients With CKD on Dialysis and HPtreatment4completed
NCT01554982
A Long-Term Safety Extension Trial of Ferric Citrate in Patients With End-Stage Renal Disease (ESRD) on Dialysistreatment3completed
NCT03163576
The Efficacy of Niacin on Hyperphosphatemia in Patients Undergoing Haemodialysistreatment4unknown_status
NCT03984760
Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysistreatment3completed
NCT02687594
Non-interventional Study to Investigate the Short and Long Term Real-life Safety, Effectiveness, and Adherence of Velphoro® in Patients With Hyperphosphataemia Undergoing Haemodialysis (HD) or Peritoneal Dialysis (PD)Not AvailableNot Availablecompleted
NCT03573089
Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)No drug interventionstreatmentNot Availablerecruiting
NCT03236701
Egg White for Phosphorus Control in Haemodialysis PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT01814904
Dose-finding Study of MCI-196treatment3terminated
NCT03079869
Transition to Ferric Citrate Among Hemodialysis and Peritoneal Dialysis Patientssupportive_care4completed
NCT00374712
Klotho Gene Polymorphism in Dialyzed Patients With HyperphosphatemiaNo drug interventionsNot AvailableNot Availableterminated
NCT04767581
Clinical Study of KHK7791 in Hyperphosphatemia Patients on HemodialysisNo drug interventionstreatment3completed
NCT02661295
A Study of Ferric Citrate to Improve Inflammation and Lipid Levelsother4terminated
NCT01191255
A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysisprevention3completed
NCT01003223
Phosphate Kinetic ModelingNo drug interventionstreatmentNot Availablecompleted
NCT00557323
Long-term Effect of Lanthanum Carbonate on BoneNot AvailableNot Availablecompleted
NCT03256838
Assess the Safety and Efficacy of Nephoxil® in Subjects With End Stage Renal Disease (ESRD) on Dialysisother4completed
NCT03367338
Low-Phosphate Diet and Fibroblast Growth Factor-23 LevelNo drug interventionstreatmentNot Availablecompleted
NCT04456803
Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysistreatment3completed
NCT02688764
A Study to Investigate the Safety and Efficacy of PA21 (Velphoro®) and Calcium Acetate (Phoslyra®) in Paediatric and Adolescent Chronic Kidney Disease (CKD) Patients With Hyperphosphataemiatreatment3terminated
NCT03644264
PA21 Safety and Efficacy in Adult Chinese Subjectstreatment3completed
NCT05897502
Explore the Effectors of The Transtheoretical Model on Nutritional Education in Patients on HemodialysisNo drug interventionspreventionNot Availablecompleted
NCT01696279
A Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety and Tolerability of Lanthanum Carbonate With Calcium Carbonate in Hyperphosphataemic Children and Adolescents With Chronic Kidney Disease on Dialysistreatment2completed
NCT01965379
Effect of Restriction of Foods Containing Phosphorus AdditivesNo drug interventionssupportive_careNot Availablecompleted
NCT01518387
Open Study of BAY77-1931 (Lanthanum Carbonate) in Continuous Ambulatory Peritoneal Dialysis Patientstreatment3completed
NCT01818687
Safety and Tolerability Study of MCI-196treatment3terminated
NCT01514851
Phase III Double-blind Comparative Study of BAY77-1931 (Lanthanum Carbonate) With Calcium Carbonatetreatment3completed
NCT01412398
Fosrenol Post-marketing Surveillance for Continuous Cyclic Peritoneal Dialysis in JapanNot AvailableNot Availablecompleted
NCT02675998
An 8-Week Study to Evaluate Tenapanor in the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients on Hemodialysis (ESRD-HD)treatment3completed
NCT01742611
Long-term Study in Chronic Kidney Disease Patients With Hyperphosphatemia Not on Dialysistreatment3completed
NCT00967993
Trial of a New Formulation of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal DiseaseNot AvailableNot Availablecompleted
NCT01755078
Long Term Evaluation of Sevelamer HCl vs. Calcium-based Phosphate Binder in the Treatment of Hyperphosphatemia in Hemodialysis Patientstreatment4completed
NCT01238588
The Effect(s) of Sevelamer Carbonate (Renvela) on Atherosclerotic Plaque Inflammation Judged by FDG-PET ScantreatmentNot Availableterminated
NCT04766385
Clinical Study of KHK7791 in Hyperphosphatemia Patients on Peritoneal DialysisNo drug interventionstreatment3completed
NCT00508885
The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patientstreatment1 / 2completed
NCT00542815
A Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemiatreatment3completed
NCT00505037
A Phase 2 Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia on Hemodialysistreatment2completed
NCT01854437
The Effect of Magnesium Oxide on Plasma Phosphate in Hemodialysis PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04551300
A Phase 2 Study to Evaluate the Safety and Efficacy of VS-505(AP301) to Treat Hyperphosphatemia in Hemodialysis Patientstreatment2completed
NCT01578200
Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate in Hemodialysis Patients : Landmark Studytreatment3completed
NCT05085275
Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Diseasetreatment3completed
NCT01503736
A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of the Effects of Ferric Citrate in Subjects With End Stage Renal Diseasetreatment3completed
NCT01725113
Management of Mineral and Bone Disease in Hemodialysis-Calcitriol vs. Paricalcitoltreatment4terminated
NCT01850641
A Phase III Study of PA21 With Calcium Carbonate in Hemodialysis Patients With HyperphosphatemiaNo drug interventionstreatment3completed
NCT01245517
The Influence of Dietary Phosphorus Education Program on Nutritional Status and Serum Phosphate Level Among Hemodialysis PatientNo drug interventionstreatmentNot Availableunknown_status
NCT04440696
To Evaluate the Patient Tolerance, Pharmacodynamics and Pharmacokinetics of Lanthanum Polystyrene Sulfonate Powdertreatment1 / 2unknown_status
NCT00769496
BAY 77-1931 Long-term Extension From Phase II StudyNo drug interventionstreatment2completed
NCT06206135
Multicenter, Open, Prospective, 48 Weeks, Observational Study ,Evaluate the Safety and Efficacy of Nephoxil CapsuleNo drug interventionsNot AvailableNot Availablerecruiting
NCT04046263
Effect of Velphoro on Serum Phosphate and Albumin in Peritoneal Dialysis Patientstreatment4completed
NCT01057186
Hypophosphatemic Rickets in NorwayNot AvailableNot Availableunknown_status
NCT03594539
Phosphate Microvascular StudyNo drug interventionsdiagnosticNot Availableunknown_status
NCT00416520
A Phase III, Multicentre, Double-Blind, Placebo-Controlled Withdrawal Study in Patients With Hyperphosphatemiatreatment3completed
NCT00772382
Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemiatreatment3completed
NCT01852682
A Phase III Study of PA21 in Peritoneal Dialysis Patients With HyperphosphatemiaNo drug interventionstreatment3completed
NCT01419327
Fosrenol Post-marketing Surveillance for Hemodialysis in JapanNot AvailableNot Availablecompleted
NCT01955876
Fosrenol Post-marketing Surveillance in JapanNot AvailableNot Availablecompleted
NCT01053676
Bioequivalence Study of BAY77-1931 Granuletreatment1completed
NCT04789876
Effectiveness of The Phosphate Mobile App on Serum Phosphorus in Adult Hemodialysis Patients With HyperphosphatemiaNo drug interventionstreatmentNot Availablecompleted
NCT02027662
Therapeutic Equivalence of OsvaRen® Tablets and OsvaRen® Granulestreatment2 / 3completed
NCT05439980
Improving Phosphate Control in Children With CKDNo drug interventionsNot AvailableNot Availablerecruiting
NCT04771780
Phosphate Binder Switch Study of KHK7791 in Hyperphosphatemia Patients on HemodialysisNo drug interventionstreatment3completed
NCT01110629
Study in Chronic Kidney Disease (CKD) Not on Dialysistreatment3completed
NCT01069692
Placebo Versus SBR759 in Lowering Phosphate in Dialysis PatientsNo drug interventionstreatment3completed
NCT00648167
A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD)treatment2completed
NCT02469467
A Dose Escalation Study of VS-505 in End Stage Renal Disease Patients Undergoing HemodialysisNo drug interventionstreatment1 / 2unknown_status
NCT00834301
An Open Label Trial to Evaluate the Effects of a Novel Renal Multivitamin on Inflammation and Other Biomarkers in Endstage Renal Disease PatientsNo drug interventionstreatment2unknown_status
NCT04278404
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)Not AvailableNot Availablerecruiting
NCT00316472
The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patientstreatment1completed
NCT01976572
Drug-Drug Interaction Study to Evaluate the Effect of Colestilan on the Pharmacokinetics of Single Doses of Candesartan Cilexetil in Healthy Subjectstreatment1completed
NCT00833768
A Randomised, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Sevelamer Carbonate Tablets Dosed Three Times a Day in Hyperphosphataemic Chronic Kidney Disease Patients Not on Dialysistreatment3terminated
NCT04256369
Rate of Termination of Premixed Parenteral Nutrition (PN) in Surgical Patients Secondary to High Serum ElectrolytesNo drug interventionsNot AvailableNot Availablecompleted
NCT00451295
A Phase III, Multi-Centre, Randomised, Placebo-Controlled Study in Combination With Ca-based P Binders in Patients With Hyperphosphatemiatreatment3terminated
NCT00837655
Effect of Sevelamer on Glucose Tolerance and Insulin Sensitivity in Patients With Chronic Renal Failure (CKD)treatmentNot Availablewithdrawn
NCT00567723
Long Term Treatment of End Stage Renal Disease Patients With Lanthanum Carbonate (Fosrenol)No drug interventionsNot AvailableNot Availablecompleted
NCT03146923
Decreasing Intakes & Absorption of Phosphorus in Haemodialysis Patients Through Food ChoicesNo drug interventionstreatmentNot Availablecompleted
NCT01057108
Double Blind Randomized Placebo Controlled Trial of FOSTRAP Chewing Gum in Patients With CKD and HyperphosphatemiaNo drug interventionstreatment1completed
NCT01510106
Ferric Citrate in Patients With End-Stage Renal Disease on Dialysistreatment3completed