NCT06594523
A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis treatment 3 not_yet_recruiting NCT05669677
Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Liver Disease No drug interventions Not Available Not Available active_not_recruiting NCT06427590
Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Healthy Subjects No drug interventions treatment 1 recruiting NCT06588699
Digoxin in NASH (CODIN) treatment 2 not_yet_recruiting NCT06195943
Feasibility, Safety and Acceptability of a Mobile Health Delivered Exercise Training Program in Patients With Nonalcoholic Steatohepatitis No drug interventions prevention Not Available recruiting NCT04702490
Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH treatment 2 unknown_status NCT05479721
LITMUS Imaging Study No drug interventions Not Available Not Available active_not_recruiting NCT06523179
Evaluation of Risk of hEpatocellular Carcinoma No drug interventions prevention Not Available recruiting NCT04302051
Assessment of Fatty Liver With Thermo-acoustic Device No drug interventions Not Available Not Available recruiting NCT05804305
Misoprostol for NASH treatment 2 completed NCT06315361
DIAbetes and NAFLD No drug interventions Not Available Not Available active_not_recruiting NCT06124261
Androgens and NAFLD Longitudinal Cohort Study No drug interventions Not Available Not Available recruiting NCT06322628
A Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of VSA006 in Chinese NASH Patients No drug interventions treatment 2 not_yet_recruiting NCT04232293
Screening of Liver Fibrosis Using Blood Tests in Patients With Type 2 Diabetes Mellitus No drug interventions diagnostic Not Available recruiting NCT05560607
Knockdown of HSD17B13 mRNA, Pharmacokinetics, Safety, and Tolerability, of AZD7503 in Non-Alcoholic Fatty Liver Disease No drug interventions other 1 completed NCT06348706
Effect of Dipeptidyl Peptidase- 4 Inhibitors on Non-Alcoholic Steatohepatitis and Type 1 Diabetes No drug interventions treatment 3 completed NCT05874336
An Open-Label, Two-Part Study Designed to Assess the Absolute Bioavailability and Mass Balance of Aramchol treatment 1 completed NCT04442334
The European NAFLD Registry No drug interventions Not Available Not Available recruiting NCT04783116
Plant Stanols and Liver Inflammation in Overweight and Obese Children No drug interventions treatment Not Available unknown_status NCT05193916
A Phase II Clinical Trial of Chiglitazar for NASH treatment 2 completed NCT04048135
A Multiple Ascending Dose Study of Pegozafermin in Participants With Biopsy Confirmed Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH treatment 1 / 2 completed NCT05500222
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) treatment 3 recruiting NCT06308757
Role of the Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Non-Alcoholic Steatohepatitis (NASH) With Fibrosis No drug interventions treatment Not Available recruiting NCT01269320
Natural Soybean-derived Femarelle ®for Patients With Non Alcoholic Fatty Liver Disease No drug interventions treatment 4 withdrawn NCT06354491
An Imaging-based Quantitative Biomarker Assay for NAFLD in Children No drug interventions Not Available Not Available recruiting NCT06364462
Precise Evaluation Criteria for Histological Regression of NASH Fibrosis No drug interventions Not Available Not Available not_yet_recruiting NCT06338969
The Impact of Different Carbohydrate Restriction After a Gastric Bypass on the Ketosis and Ketoacidosis No drug interventions treatment Not Available recruiting NCT06563921
RE and Probiotics in MAFLD/NAFLD No drug interventions treatment Not Available not_yet_recruiting NCT06176079
Hyperpolarized Pyruvate (13C) Magnetic Resonance Imaging In Patients With Fatty Liver Disease Not Available Not Available recruiting NCT05784779
Phase Ib/II Study to Evaluate the Efficacy and Safety of GH509 Versus Placebo in Patients With NASH/NAFLD No drug interventions treatment 1 / 2 recruiting NCT02923154
Efficacy and Safety of MT-3995 in Patients With Non-Alcoholic Steatohepatitis(NASH) treatment 2 completed NCT05994677
Psoriasis and Non Alcoholic Steatohepatitis: Is There a Shared Inflammatory Network ? No drug interventions Not Available Not Available not_yet_recruiting NCT06352177
Digital Therapeutic Lifestyle Intervention Program for Patients With MASLD No drug interventions treatment Not Available not_yet_recruiting NCT06342947
ALG-055009 in Non-cirrhotic Adults With MASH (HERALD) No drug interventions treatment 2 active_not_recruiting NCT04006145
A Phase 2 Study of Elobixibat in Adults With NAFLD or NASH treatment 2 completed NCT05632861
HuHuangLianzonggan Capsule in Subjects With Nonalcoholic Steatohepatitis: a Phase 2 tRial(HHL-HEPAR) No drug interventions treatment 2 recruiting NCT05935488
Early Liver Disease Breath Detection No drug interventions Not Available Not Available recruiting NCT05383456
The Visceral Adiposity Measurement and Observation Study No drug interventions Not Available Not Available completed NCT05203237
Phase 1 Study to Evaluate the Safety and Tolerability of VK2735 No drug interventions treatment 1 recruiting NCT05857319
Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients (SCOOP-RNPC) No drug interventions Not Available Not Available not_yet_recruiting NCT04565717
A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH) No drug interventions treatment 1 terminated NCT06410924
A Study to Evaluate DD01 in Overweight/Obese Subjects With MASLD/MASH No drug interventions treatment 2 recruiting NCT03187496
Drug-drug Interaction Study Between EDP-305, Midazolam, Caffeine and Rosuvastatin in Healthy Volunteers. basic_science 1 completed NCT03207425
A Study of EDP-305 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers No drug interventions basic_science 1 completed NCT05327127
Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis treatment 2 recruiting NCT06491576
A Clinical Trial of BGT-002 Tablets in Subjects With Nonalcoholic Steatohepatitis No drug interventions treatment 1 / 2 completed NCT05015491
Effects of Online App Weight Loss Programs on Liver Health in Obese Adults No drug interventions treatment Not Available completed NCT04925362
THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis) No drug interventions diagnostic Not Available not_yet_recruiting NCT06193629
A Multicenter, Double-blind, Placebo-randomized Controlled Clinical Study on the Treatment of Non-alcoholic Steatohepatitis With Tibetan Drug Langqing Atar No drug interventions treatment Not Available recruiting NCT03980912
Validation of the LiverFASt Test and the Associated Fibrosis Staging Scores Compared to Liver Tissue Pathology Via Liver Biopsy No drug interventions Not Available Not Available withdrawn NCT05519475
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Non-Alcoholic Steatohepatitis (NASH) in Adult Participants at Increased Genetic Risk for This Condition No drug interventions treatment 2 recruiting NCT06121999
Behavioral Lifestyle Intervention for Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults No drug interventions treatment Not Available enrolling_by_invitation NCT06492330
Efficacy and Safety of CS0159 Combined With Semaglutide in MASH Patients With Obesity and T2DM treatment Not Available recruiting NCT06374875
Fibrosis Lessens After Metabolic Surgery No drug interventions treatment 4 recruiting NCT06108219
A Phase 2b, Study Evaluating Miricorilant in Adult Patients With Nonalcoholic Steatohepatitis/Metabolic Dysfunction-Associated Steatohepatitis (MONARCH) treatment 2 recruiting NCT02548351
Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment treatment 3 terminated NCT05989711
Efficacy and Safety of Pemvidutide in Subjects With Nonalcoholic Steatohepatitis (NASH) (IMPACT Trial) treatment 2 active_not_recruiting NCT06309992
A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight treatment 3 recruiting NCT04880031
A Study of BOS-580 in Obese Subjects At Risk For, or with Biopsy-confirmed, Nonalcoholic Steatohepatitis (NASH) with an Extension No drug interventions treatment 2 recruiting NCT05118360
Study to Evaluate the Safety, Tolerability, and Efficacy of ASC41 in Adults With NASH No drug interventions treatment 2 withdrawn NCT06024408
A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor No drug interventions treatment 1 recruiting NCT06151964
A Trial to Learn How Safe AZD9550 is in People With or Without Type 2 Diabetes Who Are Overweight or Obese No drug interventions treatment 1 / 2 recruiting NCT04165343
Evaluation of Multi-Organ Metabolism and Perfusion in NAFLD by Total Body Dynamic PET Scan on EXPLORER No drug interventions Not Available Not Available completed NCT04281303
Endoscopic Bariatric Therapy in NASH Cirrhosis No drug interventions Not Available Not Available unknown_status NCT04913090
A Phase I Clinical Trial of XZP-5610 Tablets in Healthy Subjects No drug interventions treatment 1 unknown_status NCT04546984
Multiple Dose Safety, Tolerability, PK，PD and Food Effect Study of HEC96719 in Healthy Adult Subjects No drug interventions treatment 1 completed NCT02781584
Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH) treatment 2 completed NCT05591079
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of CS0159 in Subjects With NASH treatment 2 completed NCT04880187
Safety, Tolerability, and Efficacy of AXA1125 in NASH With Fibrosis No drug interventions treatment 2 unknown_status NCT02158351
Gut Microbiota and Modulation of Liver Damage in NAFLD No drug interventions Not Available Not Available completed NCT06037577
Subcutaneous Doses of CM-101 as a Treatment for Medical Conditions Involving Inflammatory and Fibrotic Mechanisms in Healthy Male Subjects treatment 1 completed NCT02913105
Safety, Tolerability, Pharmacokinetics and Efficacy of LMB763 in Patients With NASH treatment 2 terminated NCT02854605
Evaluating the Safety, Tolerability, and Efficacy of GS-9674 in Participants With Nonalcoholic Steatohepatitis (NASH) treatment 2 completed NCT06168383
To Evaluate the Efficacy and Safety of HSK31679 in Chinese Patients With Non-Alcoholic Steatohepatitis (NASH) . No drug interventions treatment 2 recruiting NCT04977661
Comparing the Effects of Vitamin E, Ursodeoxycholic Acid and Pentoxyfylline on Egyptian Non-alcoholic Steatohepatitis (NASH) Patients treatment 4 completed NCT04019561
A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in Obese Subjects With NAFLD/NASH. treatment 2 completed NCT05402371
A Study to Evaluate the Efficacy and Safety of Rencofilstat in Subjects With NASH and Advanced Liver Fibrosis treatment 2 active_not_recruiting NCT00706537
Phase 1 Pharmacokinetic Study Of CP-945598 In Patients With NASH basic_science 1 completed NCT01899859
Phase 1 Study to Evaluate Safety of GR-MD-02 in Subjects With Non-Alcoholic Steatohepatitis (NASH) and Advanced Fibrosis treatment 1 completed NCT03008070
Phase 2b Study in NASH to Assess IVA337 treatment 2 completed NCT01694849
Phase IIb Study to Evaluate the Efficacy and Safety of GFT505 Versus Placebo in Patients With Non-Alcoholic Steatohepatitis (NASH) treatment 2 completed NCT03861819
Feasibility of VIIT in Adults With NASH No drug interventions other Not Available completed NCT04065841
Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy, Compared With Placebo in Adult Patients With NASH and Liver Fibrosis. treatment 2 terminated NCT02098317
DHA and Vitamin D in Children With Biopsy-proven NAFLD treatment 3 completed NCT02443116
Study of NGM282 in Patients With Nonalcoholic Steatohepatitis (NASH) treatment 2 completed NCT02605616
Use of a Novel Drug in People With Non-alcoholic Steatohepatitis (NASH) or Non-alcoholic Fatty Liver Disease (NAFLD) No drug interventions treatment 2 terminated NCT00666016
Exploratory Study to Assess the Short Term Effect on Liver Enzymes and the Safety of TRO19622 in Patients With Non-Alcoholic Steatohepatitis (NASH) treatment 2 completed NCT04052516
A Phase 2b Study of Icosabutate in Fatty Liver Disease treatment 2 completed NCT05552274
FTIH of ECC4703 in Healthy Volunteers No drug interventions treatment 0 completed NCT03025074
Blood Collection Biorepository for Liver Disease Research No drug interventions Not Available Not Available recruiting NCT02196831
Tesamorelin Effects on Liver Fat and Histology in HIV treatment Not Available completed NCT03151473
Longitudinal Observational Study Of Chinese With NAFLD/NASH No drug interventions Not Available Not Available recruiting NCT04481594
A Study to Evaluate the Safety and Tolerability of Single and Multiple Ascending Doses of HPN-01 in Healthy Subjects No drug interventions treatment 1 unknown_status NCT05117489
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Patients With Presumed Nonalcoholic Steatohepatitis (NASH) treatment 1 completed NCT05842512
Study of ADI-PEG 20 Versus Placebo in Subjects With NASH treatment 2 recruiting NCT04616014
A Study of Oral Insulin to Reduce Liver Fat Content in Type 2 Diabetes Patients With Nonalcoholic Steatohepatitis (NASH) treatment 2 completed NCT02927314
A Study of the Efficacy and Safety of CF102 in the Treatment of Non-Alcoholic Fatty Liver Disease treatment 2 completed NCT04521114
Leronlimab (PRO 140) in Patients With Nonalcoholic Steatohepatitis treatment 2 completed NCT04607655
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Orally Administered GB1211 in Participants With Suspected or Confirmed Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis treatment 1 / 2 withdrawn NCT02856555
Study to Evaluate Safety, Tolerability, and Efficacy of GS-0976 in Adults With Nonalcoholic Steatohepatitis treatment 2 completed NCT04140123
Tolerability, Efficacy, and PK of ZSP1601 in Patients With Non-Alcoholic Steatohepatitis (NASH) No drug interventions treatment 1 / 2 completed NCT02044523
Noninvasive Staging of Liver Fibrosis: MR vs Ultrasound No drug interventions Not Available Not Available completed NCT02891408
Study to Evaluate the Pharmacokinetics of Firsocostat or Fenofibrate in Adults With Normal and Impaired Hepatic Function treatment 1 completed NCT03823703
Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Participants With Presumed Nonalcoholic Steatohepatitis (NASH) treatment 2 terminated NCT05765890
Barriers to MASLD Management in Europe: Findings From a Multidisciplinary HCP-survey No drug interventions Not Available Not Available completed NCT02855164
Study of Safety and Efficacy of Tropifexor (LJN452) in Patients With Non-alcoholic Steatohepatitis (NASH) treatment 2 terminated NCT05050721
Natural History of Non Alcoholic Fatty Liver Disease and Predictors of Advanced Fibrosis No drug interventions Not Available Not Available withdrawn NCT04104321
A Clinical Study to Evaluate the Efficacy and Safety of Aramchol in Subjects With NASH (ARMOR) treatment 3 suspended NCT02654002
Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GS-9674 (Cilofexor), and the Effect of Food on GS-9674 Pharmacokinetics and Pharmacodynamics treatment 1 completed NCT01950884
Lifestyle Versus Ezetimibe Plus Lifestyle in Patients With Non-alcoholic Steatohepatitis treatment 4 unknown_status NCT03392779
Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP1601, and the Effect of Food on ZSP1601 Pharmacokinetics No drug interventions treatment 1 completed NCT04483947
A Study to Assess Safety, Tolerability, PK and PD of AZD2693 in Non-alcoholic Steatohepatitis Patients No drug interventions treatment 1 completed NCT00845845
Fish Oil and Diet for the Treatment of Non-Alcoholic Steatohepatitis (NASH) treatment 2 terminated NCT01265498
The Farnesoid X Receptor (FXR) Ligand Obeticholic Acid in NASH Treatment Trial(FLINT) treatment 2 completed NCT04282005
Metabolic Surgery for Steato-Hepatitis No drug interventions treatment Not Available unknown_status NCT04267393
Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH) No drug interventions treatment 2 terminated NCT02754037
Non-alcoholic Fatty Liver Disease Parametric PET (FLiPP) Study No drug interventions Not Available Not Available active_not_recruiting NCT01638832
Association of Non-alcoholic Fatty Liver Disease and Coronary Artery Disease No drug interventions diagnostic Not Available unknown_status NCT05384652
Simultaneous Quantification of Liver Fat Content, Fatty Acid Composition, and Fibrosis Using Spin-lock MRI for Steatohepatitis Assessment No drug interventions Not Available Not Available not_yet_recruiting NCT04682600
The Sonic Incytes Liver Incytes System, Evaluation of Liver Fibrosis and Steatosis Versus MRE and MRI PDFF No drug interventions diagnostic Not Available active_not_recruiting NCT02653300
A Pilot Study to Assess the Safety of Oral Insulin in Patients With Nonalcolholic Steatohepatitis (NASH) treatment 2 completed NCT05553470
Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Miricorilant treatment 1 recruiting NCT04194242
The Tolerability , Pharmacokinetics and Pharmacodynamics Study of HEC96719 Tablets in Healthy Adult Subjects No drug interventions treatment 1 completed NCT04820036
A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG) No drug interventions other Not Available active_not_recruiting NCT06216041
To Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effects of IMM-H014 in Healthy Subjects No drug interventions treatment 1 recruiting NCT02316717
A Phase ll Study of IMM-124E for Patients With Non-alcoholic Steatohepatitis No drug interventions treatment 2 completed NCT02466516
Safety, Tolerability, and Efficacy of GS-4997 Alone or in Combination With Simtuzumab (SIM) in Adults With Nonalcoholic Steatohepatitis (NASH) and Fibrosis Stages F2-F3 treatment 2 completed NCT01571063
Treatment of Non-alcoholic Steatohepatitis (NASH) Patients With Vitamin D treatment 2 completed NCT04004325
A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic Steatohepatitis No drug interventions treatment 1 / 2 terminated NCT05712265
Study to Evaluate the Effects of a Cytochrome P450 2C19 Inhibitor on the Pharmacokinetics of Miricorilant treatment 1 completed NCT03572465
Quantitative Ultrasound Techniques for Diagnosis of Nonalcoholic Steatohepatitis No drug interventions Not Available Not Available recruiting NCT02654665
Comparing Effects of Liraglutide and Bariatric Surgery on Weight Loss, Liver Function, Body Composition, Insulin Resistance, Endothelial Function and Biomarkers of Non-alcoholic Steatohepatitis (NASH) in Obese Asian Adults treatment 3 unknown_status NCT04771273
A Study to Test Safety and Efficacy of BI456906 in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3) treatment 2 completed NCT05423327
Genetic Data Collection in Adult Participants to Identify Genetic Variants of Known Importance in Non-alcoholic Steatohepatitis (NASH) No drug interventions screening Not Available terminated NCT04134091
The Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis treatment 2 completed NCT02612662
A Study to Assess the Safety and Tolerability of Single Doses of AZD4076 in Healthy Male Subjects No drug interventions basic_science 1 active_not_recruiting NCT05623189
HTD1801 in Adults With Nonalcoholic Steatohepatitis and Liver Fibrosis Who Have Type 2 Diabetes or Pre-Diabetes No drug interventions treatment 2 active_not_recruiting NCT05692492
A Randomized, Double-blind, Placebo-controlled Study of ZSP1601 in Adult Subjects With Nonalcoholic Steatohepatitis (NASH) No drug interventions treatment 2 recruiting NCT05727644
A Research Study Looking Into Blood and Urine Levels of the Medicine NNC0194-0499 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney Function No drug interventions treatment 1 completed NCT03517540
Study of Safety, Tolerability, and Efficacy of a Combination Treatment of LJN452 and CVC in Adult Patients With NASH and Liver Fibrosis treatment 2 completed NCT04060368
Efficacy and Safety of Endoscopic Sleeve Gastroplasty Versus Laparoscopic Sleeve Gastrectomy in Obese Subjects With NASH No drug interventions treatment Not Available unknown_status NCT05320146
A Sub Study of the Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Patients With Presumed Nonalcoholic Steatohepatitis (NASH) No drug interventions Not Available Not Available completed NCT02808312
Pharmacokinetics and Pharmacodynamics of Cilofexor in Adults With Normal and Impaired Hepatic Function treatment 1 completed NCT04639414
Combined Active Treatment in Type 2 Diabetes With NASH treatment 4 active_not_recruiting NCT01894438
Mediterranean Lifestyle Intervention in Patients With Non-alcoholic Fatty Liver Disease No drug interventions treatment Not Available completed NCT03451279
A Nonabsorbable Ileal Apical Sodium-Dependent Bile Acid Transporter Inhibitor for Nonalcoholic Steatohepatitis treatment 2 withdrawn NCT06161571
A Study Evaluating Efruxifermin in Subjects with Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) treatment 3 recruiting NCT06623084
Integrated Phenotyping of the Gut-plAtelet-Liver AXIS in the Progression of Chronic Liver Disease (iGAL-AXIS) No drug interventions Not Available Not Available not_yet_recruiting NCT04505436
Study to Evaluate Efficacy, Safety and Tolerability of HM15211 in Subjects treatment 2 recruiting NCT05364684
The Impact of Ibutamoren on Nonalcoholic Fatty Liver Disease treatment 2 active_not_recruiting NCT04591106
Quantifying Body Composition and Liver Disease in Children Using Free-Breathing MRI and MRE No drug interventions Not Available Not Available enrolling_by_invitation NCT04653103
NASH in Subjects With Different Classes of Obesity No drug interventions Not Available Not Available unknown_status NCT05037890
Effects of Plant Sterols and Stanols on Liver Inflammation No drug interventions prevention Not Available unknown_status NCT03508687
Study of Gemcabene in Adults With FPLD treatment 1 / 2 completed NCT03976687
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EYP001a in Healthy Volunteers and Nonalcoholic Steatohepatitis Patients No drug interventions treatment 1 completed NCT04781933
Interest in "Combo" (a Combination of Dietary Supplements Including Probiotics) in NASH Improvement No drug interventions treatment Not Available recruiting NCT04383951
Safety and Efficacy of Ketogenic Diet for Promoting Weight Loss in Obese Individuals With Compensated NASH Cirrhosis No drug interventions treatment Not Available active_not_recruiting NCT05128253
Characterization of the Platelet Inflammatory Response in NAFL and NASH No drug interventions Not Available Not Available unknown_status NCT03801577
Hepaxa Management of Non-alcoholic Fatty Liver Disease No drug interventions treatment Not Available unknown_status NCT04240145
Non Alcoholic Steatohepatitis in Relation to Visceral and Subcutaneous Fat No drug interventions Not Available Not Available unknown_status NCT04146805
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BLD-0409 in Healthy Subjects treatment 1 completed NCT03783897
A Drug-drug Interaction Study to Investigate the Effect of Coadministration of EDP-305 on the PK of a Combined Oral Contraceptive in Healthy Female Subjects basic_science 1 completed NCT03748628
Absorption, Metabolism and Excretion (AME) Study of [14C]EDP-305 in Healthy Male Subjects No drug interventions basic_science 1 completed NCT04849728
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 ) treatment 3 recruiting NCT04653311
Evaluation of an Endoscopic Sutured Gastroplasty in Patients With NonAlcoholic Steatohepatitis (NASH) and Fibrosis. No drug interventions treatment Not Available unknown_status NCT04685993
A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 Trial treatment 2 completed NCT05232071
Placebo-controlled, Proof-of-concept Study to Evaluate the Safety and Efficacy of Lanifibranor Alone and in Combination With SGLT2 Inhibitor EmpaGliflozin in patiEnts With NASH and Type 2 Diabetes Mellitus treatment 2 completed NCT02581085
Tocotrienol Against the Progression of End Stage Liver Disease other 2 recruiting NCT05108415
Development and Validation of a Multi-target, Blood-based NAFLD Diagnosis Test No drug interventions Not Available Not Available not_yet_recruiting NCT05257200
Gut Permeability and Bariatric-metabolic Surgery No drug interventions Not Available Not Available recruiting NCT04109742
Curcumin for Pediatric Nonalcoholic Fatty Liver Disease treatment 2 withdrawn NCT03291249
Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM treatment 2 withdrawn NCT03538236
Intragastric Balloon With Lifestyle Intervention vs. Lifestyle Intervention in Obese Patients With NASH No drug interventions treatment Not Available withdrawn NCT04298736
Bariatric Surgery vs. Lifestyle Modification for NASH No drug interventions treatment Not Available unknown_status NCT04709913
Multiple Ascending Dose Study of HU6 in High BMI Volunteers No drug interventions treatment 1 completed NCT03534141
Mild Hypothermia and Acute Kidney Injury in Liver Transplantation No drug interventions prevention Not Available terminated NCT05338034
Phase 2a Study of HPG1860 in Subjects With NASH No drug interventions prevention 2 unknown_status NCT04972396
ALT-801 DDI Study in Healthy Volunteers other 1 completed NCT04306939
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study No drug interventions Not Available Not Available suspended NCT03551522
A Study to Evaluate Seladelpar in Subjects With Nonalcoholic Steatohepatitis (NASH) treatment 2 terminated NCT03022630
Palliative Care for Non-Malignant Diseases (COMPASS Trial) No drug interventions supportive_care Not Available terminated NCT04841057
Biometabolic Outcomes After Weight Loss Surgery: An Individualized Approach No drug interventions basic_science Not Available enrolling_by_invitation NCT05120557
Point-of-care Ultrasound Screening and Assessment of Chronic Liver Diseases and NASH No drug interventions diagnostic Not Available unknown_status NCT04173065
A Study to Assess the Efficacy and Safety of VK2809 for 52 Weeks in Subjects With Biopsy Proven NASH treatment 2 completed NCT03858920
The Liver in the World Trade Center Health Program General Responder Cohort and Controls No drug interventions Not Available Not Available completed NCT03970031
A Study of MSDC-0602K to Assess Glycemic Control and Cardiovascular Outcomes in Patients With Pre-T2D or T2D and NAFLD/NASH No drug interventions treatment 3 unknown_status NCT03587831
Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis No drug interventions treatment Not Available recruiting NCT03308773
Disease Prevention in Clinical Practice Base on Patient Specific Physiology No drug interventions Not Available Not Available enrolling_by_invitation NCT03726827
A Self Selected Population Study of Undiagnosed NAFLD and NASH, Using an Echosens FibroScan, in at Risk Populations No drug interventions Not Available Not Available completed NCT04679376
Statins for the Treatment of NASH treatment 2 recruiting NCT04897594
AVIATION Study: A Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of TERN-201 in Patients With Non-Cirrhotic Non-Alcoholic Steatohepatitis No drug interventions treatment 1 completed NCT05023044
Nonalcoholic Fatty Liver Disease in HIV Database No drug interventions Not Available Not Available recruiting NCT05195944
Semaglutide vs Sitagliptin treatment 4 enrolling_by_invitation NCT03332940
An Evaluation of the Safety of Intravenous Tc 99m Tilmanocept and a Comparison of Imaging With Sulfur Colloid in Subjects With and Without NASH diagnostic 1 completed NCT03976401
A Study of Efruxifermin in Subjects With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH) No drug interventions treatment 2 completed NCT03611101
Companion Protocol for ¹³C-Methacetin Breath Tests in BMS: NCT03486899, NCT03486912 Referenced Trials diagnostic Not Available completed NCT01406704
Effects of Rosiglitazone and Alpha-lipoic Acid on the Patients With Pathologically Proved NASH prevention 4 terminated NCT05441904
Study to Assess the Safety, Tolerability, and Pharmacokinetics of PXL770 in Healthy Subjects. No drug interventions treatment 1 completed NCT04480710
A Study of CRV431 Dosed Once Daily in NASH Induced F2 and F3 Subjects treatment 2 completed NCT04054310
Non-Invasive Quantification of Liver Health in NASH (N-QUAN) No drug interventions diagnostic Not Available recruiting NCT04643795
Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects treatment 1 completed NCT03576755
Spironolactone Therapy In Young Women With NASH other 1 / 2 completed NCT05039450
A Study of Efruxifermin in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (Symmetry) No drug interventions treatment 2 active_not_recruiting NCT03753308
Mechanism of DCs Dysfunction in Chronic HBV Infection No drug interventions Not Available Not Available unknown_status NCT04321343
Study of PXL065 in Patients With Nonalcoholic Steatohepatitis (NASH) No drug interventions treatment 2 completed NCT04773964
Study to Evaluate MET642 in Patients With NASH No drug interventions treatment 2 completed NCT04616664
Diagnostic Accuracy of the "LLIFT", a Novel Non-invasive Biomarker for the Diagnosis of Non Alcoholic Fatty Liver (NAFL) and SteatoHepatitis (NASH) in a Population With High Risk of Metabolic Syndrome" No drug interventions Not Available Not Available recruiting NCT03963921
Safety and Tolerability of HepaStem in Patients With Cirrhotic and Pre-cirrhotic NASH Patients treatment 1 / 2 completed NCT00678587
Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocytopenia Undergoing Elective Invasive Procedures treatment 3 terminated NCT03669133
Vitamin E for NASH Treatment in HIV Infected Individuals treatment 2 terminated NCT04874233
Phase 2a Study of HU6 in Subjects With Elevated Liver Fat and High BMI Volunteers No drug interventions treatment 2 completed NCT03648554
Researching an Effect of GLP-1 Agonist on Liver STeatosis (REALIST) treatment 4 unknown_status NCT03968354
NASH and Type 2 Diabetes: Role of the Receptor Activator of Nuclear Factor-κB (RANK) and Its Ligand (RANKL) No drug interventions Not Available Not Available unknown_status NCT04808154
A Phase I Study to Investigate the Safety, Tolerability and Pharmacokinetic Profile of SNP-630 in Health Subjects. No drug interventions treatment 1 completed NCT04292977
Splanchnic and Systemic VLDL-TG and FFA Balance No drug interventions Not Available Not Available completed NCT04328077
LIFT Study: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of TERN-101 in Subjects With Non-Cirrhotic Non-Alcoholic Steatohepatitis (NASH) treatment 2 completed NCT03610945
Drug-drug Interaction Study Between EDP-305, Fluconazole and Quinidine in Healthy Volunteers basic_science 1 completed NCT03213145
Drug-drug Interaction Study Between EDP-305, Intraconazole and Rifampin in Healthy Volunteers basic_science 1 completed NCT04561245
ALT-801 in Healthy Overweight and Obese Volunteers to Study Safety and Tolerability treatment 1 completed NCT03289897
Non-invasive Rapid Assessment of NAFLD Using Magnetic Resonance Imaging With LiverMultiScan No drug interventions other Not Available completed NCT02962297
Vitamin E Versus Placebo for the Treatment of Non Diabetic Patients With Nonalcoholic Steatohepatitis treatment Not Available completed NCT04976283
Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver treatment 4 unknown_status NCT04929483
Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH) treatment 2 active_not_recruiting NCT05090111
A Study of ALG-055009 in Healthy Volunteers and Subjects With Hyperlipidemia No drug interventions treatment 1 completed NCT05022693
PK Study of Liquid Formulation of BIO89-100 in Subjects With NASH With Compensation Cirrhosis other 1 completed NCT03468556
A Randomized, Double-Blind, Placebo Controlled Study to Assess the Efficacy and Safety of SNP-610 for the Treatment of Patients With Non-alcoholic Steatohepatitis No drug interventions treatment 2 not_yet_recruiting NCT03912532
Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study In Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3) treatment 2 completed NCT04066400
Role of a Wheat Containing Diet on Non-alcoholic Steatohepatitis No drug interventions treatment Not Available completed NCT03490370
Proof of Concept ELectro-Stimulation of Muscles to resolVe Insulin Resistance in NASH No drug interventions treatment Not Available completed NCT04371042
PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies No drug interventions Not Available Not Available recruiting NCT05499949
The Franciscus Obesity NASH Study No drug interventions Not Available Not Available not_yet_recruiting NCT03897218
Dietary Modulation of Intestinal Microbiota as Trigger of Liver Health: Role of Bile Acids - "A Diet for Liver Health" No drug interventions prevention Not Available completed NCT03294941
The HepQuant SHUNT Test for Monitoring Liver Disease and Treatment Effects by Measuring Liver Function and Physiology No drug interventions diagnostic 2 terminated NCT04463017
Ascending Dose Study of HU6 in Healthy Volunteers No drug interventions treatment 1 completed NCT03864835
NASH-FITTER: Nonalcoholic Steatohepatitis Fitness Intervention Treatment Targeting Endothelial Dysfunction Reversal No drug interventions treatment Not Available withdrawn NCT05415722
DUET Study: A Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Orally Administered TERN-501 as Monotherapy and in Combination With TERN-101 in Noncirrhotic Adults With Presumed Non-Alcoholic Steatohepatitis treatment 2 completed NCT03997422
Hepatic Energy Fluxes in NASH and NAS Patients No drug interventions treatment Not Available recruiting NCT05284448
Pentoxifylline in Treatment of Patients With Nonalcoholic Steatohepatitis treatment 3 completed NCT03472157
A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients No drug interventions treatment Not Available recruiting NCT04232566
Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity No drug interventions Not Available Not Available recruiting NCT03868566
An Open-Label Study to Assess the Hepatic Protection Effect of SNP-612, in Patients With NAFLD No drug interventions treatment 2 terminated NCT03678727
Effects of Exercise on VLDL-TG Metabolism No drug interventions Not Available Not Available completed NCT03132662
Omega-3 vs Very Low Calorie Diet for Liver Size Reduction No drug interventions treatment Not Available unknown_status NCT04308980
Safety and Tolerability of Novel Medical Nutrition Products for NAFLD Treatment No drug interventions treatment 2 / 3 unknown_status NCT03900429
A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis treatment 3 active_not_recruiting NCT04767529
A Study of Efruxifermin in Non-Cirrhotic Subjects With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH) No drug interventions treatment 2 active_not_recruiting NCT03439189
Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14 diagnostic Not Available completed NCT02690792
Effect of Vitamin E on Non-Alcoholic Fatty Liver Disease No drug interventions treatment Not Available completed NCT02784444
A Study to Evaluate the Safety, Tolerability & Efficacy of MSDC-0602K in Patients With NASH No drug interventions treatment 2 completed NCT04618744
A Study to Assess the Safety and Efficacy of Oral Insulin in T2DM Patients With Nonalcoholic Steatohepatitis (NASH) treatment 2 completed NCT04833140
Estrogen Administration for the Treatment of NASH in Postmenopausal Women treatment 3 recruiting NCT04677101
Liquid Biopsy for NASH and Liver Fibrosis No drug interventions Not Available Not Available completed NCT04365868
Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis prevention 2 / 3 active_not_recruiting NCT05165446
Novel MRE Technique to Assess a Risk Factor for Liver Cancer No drug interventions Not Available Not Available active_not_recruiting NCT04697810
Namodenoson in the Treatment of Non-Alcoholic Steatohepatitis (NASH) treatment 2 recruiting NCT04561895
Adipokine Genetic Variations in predictingNAFLD Progression to NASH in Egyptian Patients No drug interventions Not Available Not Available completed NCT06528314
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH treatment 3 recruiting NCT03536650
Effect of DMR in the Treatment of NASH No drug interventions treatment Not Available completed NCT04395950
Effects of ACC Inhibitor on Lipid and Lipoprotein Metabolism basic_science 1 withdrawn NCT04576923
Quantitative Ultrasound With Liver Incytes for Evaluation of Non-Alcoholic Fatty Liver Disease No drug interventions diagnostic Not Available terminated NCT06592820
Shear Wave Elastography Registry Study No drug interventions Not Available Not Available not_yet_recruiting NCT06573528
Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS060380 in Healthy and Elevated LDL-C Subjects No drug interventions treatment 1 not_yet_recruiting NCT05651724
Global Research Initiative for Patients Screening on MASH No drug interventions Not Available Not Available recruiting NCT06138821
Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial No drug interventions treatment Not Available not_yet_recruiting NCT06485245
Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS060304 in Healthy and Elevated LDL-C Subjects No drug interventions treatment 1 not_yet_recruiting NCT06562361
A Microdose Trial Investigating Binding of [68Ga]Ga-DOTA-CYS-ATH001 in Healthy Subjects and Different Patient Groups. No drug interventions diagnostic 0 recruiting NCT06446908
Acceptability and Feasibility of a New Approach to Engage Patients With Steatotic Liver Disease in Physical Activity No drug interventions other Not Available not_yet_recruiting