Folic acid antagonist overdose

Also known as: Folic Acid Deficiency / Folic Acid Deficiencies / Folate deficiency / Disorder of folic acid / Biotin deficiency

DrugDrug NameDrug Description
DB00115CyanocobalaminA vitamin available in many formulations to correct vitamin B12 deficiency.
DB14491Ferrous fumarateA medication used to treat iron-deficiency anemia.
DB00650LeucovorinA folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer.
DB11596LevoleucovorinA folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer.
DrugDrug NameTargetType
DB00115CyanocobalaminMethionine synthase reductasetarget
DB00115CyanocobalaminMethylmalonic aciduria type A protein, mitochondrialtarget
DB00115CyanocobalaminMethylmalonyl-CoA mutase, mitochondrialtarget
DB00115CyanocobalaminMethylmalonic aciduria and homocystinuria type C proteintarget
DB00115CyanocobalaminMethionine synthasetarget
DB00115CyanocobalaminMethylenetetrahydrofolate reductasetarget
DB00115CyanocobalaminProtein amnionlesstransporter
DB00115CyanocobalaminTranscobalamin-1transporter
DB00115CyanocobalaminTranscobalamin-2transporter
DB00115CyanocobalaminCob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrialenzyme
DB00115CyanocobalaminGastric intrinsic factortransporter
DB00115CyanocobalaminCubilintransporter
DB00115CyanocobalaminBifunctional adenosylcobalamin biosynthesis protein CobUenzyme
DB00115CyanocobalaminLow-density lipoprotein receptor-related protein 2transporter
DB00115CyanocobalaminMultidrug resistance-associated protein 1transporter
DB00115CyanocobalaminPancreatic proteasesenzyme
DB14491Ferrous fumarateTransferrin receptor protein 1target
DB14491Ferrous fumarateEgl nine homolog 1target
DB14491Ferrous fumarateHistone deacetylase 8target
DB14491Ferrous fumarateAlpha-hemoglobin-stabilizing proteintarget
DB14491Ferrous fumarateHemoglobin subunit alphatarget
DB14491Ferrous fumarateFrataxin, mitochondrialtarget
DB14491Ferrous fumarateFerritin heavy chaintarget
DB14491Ferrous fumarateFlap endonuclease 1target
DB14491Ferrous fumarateEndonuclease 8-like 1target
DB14491Ferrous fumarateEndonuclease 8-like 2target
DB14491Ferrous fumarateDNA polymerase betatarget
DB14491Ferrous fumarateCeruloplasmintarget
DB14491Ferrous fumarateSerotransferrintarget
DB00650LeucovorinSolute carrier family 22 member 8transporter
DB11596LevoleucovorinSerine hydroxymethyltransferasetarget
DrugDrug NamePhaseStatusCount
DB00158Folic acid2 / 3Recruiting1
DB00158Folic acidNot AvailableUnknown Status1