Macrolides, Lincosamides and Streptogramins

Name
Macrolides, Lincosamides and Streptogramins
Accession Number
DBCAT002202
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
RoxithromycinAn antibiotic used to treat a variety of susceptible bacterial infections.
DirithromycinFor the treatment of the following mild-to-moderate infections caused by susceptible strains of microorganisms: acute bacterial exacerbations of chronic bronchitis, secondary bacterial infection of acute bronchitis, community-acquired pneumonia, pharyngitis/tonsilitis, and...
TelithromycinAn ketolide used to treat community acquired pneumonia of mild to moderate severity.
JosamycinFor the treatment of bacterial infections.
LincomycinAn antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate.
TroleandomycinFor the treatment of bacterial infection.
MiocamycinMiocamycin is a macrolide type antimicrobial . This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia . It has shown to...
FlurithromycinNot Annotated
RokitamycinNot Annotated
MidecamycinA macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria.
PristinamycinNot Annotated
ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
AzithromycinA macrolide antibiotic used to treat a variety of bacterial infections.
ClindamycinA lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
ClarithromycinA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
SpiramycinA macrolide antimicrobial agent used in the treatment of various bacterial infections.
OleandomycinOleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus.
SolithromycinInvestigated for the treatment of community-acquired pneumonia (CAP).
Drugs & Drug Targets
DrugTargetType
Roxithromycin50S ribosomal protein L10target
RoxithromycinP-glycoprotein 1target
RoxithromycinCytochrome P450 3A4enzyme
RoxithromycinCytochrome P450 2B6enzyme
Dirithromycin23S ribosomal RNAtarget
DirithromycinCytochrome P450 3A4enzyme
Telithromycin23S ribosomal RNAtarget
TelithromycinCytochrome P450 3A4enzyme
TelithromycinSolute carrier organic anion transporter family member 1B1transporter
TelithromycinSolute carrier organic anion transporter family member 1B3transporter
Josamycin50S ribosomal protein L4target
Lincomycin23S ribosomal RNAtarget
LincomycinAlpha-1-acid glycoprotein 1carrier
TroleandomycinCytochrome P450 3A5enzyme
TroleandomycinCytochrome P450 3A43enzyme
Troleandomycin50S ribosomal protein L4target
Troleandomycin50S ribosomal protein L32target
TroleandomycinP-glycoprotein 1transporter
TroleandomycinCytochrome P450 2C8enzyme
TroleandomycinCytochrome P450 3A4enzyme
TroleandomycinNuclear receptor subfamily 1 group I member 2target
TroleandomycinCytochrome P450 3A7enzyme
MiocamycinCytochrome P450 3A4enzyme
FlurithromycinCytochrome P450 3A4enzyme
RokitamycinCytochrome P450 3A4enzyme
MidecamycinCytochrome P450 3A4enzyme
Erythromycin23S ribosomal RNAtarget
ErythromycinCytochrome P450 3A4enzyme
ErythromycinCytochrome P450 3A7enzyme
ErythromycinP-glycoprotein 1transporter
ErythromycinSolute carrier organic anion transporter family member 1B1transporter
ErythromycinMotilin receptortarget
ErythromycinPotassium voltage-gated channel subfamily H member 2target
ErythromycinCytochrome P450 3A5enzyme
ErythromycinSolute carrier organic anion transporter family member 1B3transporter
ErythromycinBile salt export pumptransporter
ErythromycinCanalicular multispecific organic anion transporter 1transporter
ErythromycinSolute carrier organic anion transporter family member 1A2transporter
Azithromycin23S ribosomal RNAtarget
AzithromycinP-glycoprotein 1transporter
AzithromycinCytochrome P450 3A4enzyme
AzithromycinProtein-arginine deiminase type-4target
AzithromycinCanalicular multispecific organic anion transporter 1transporter
ClindamycinCytochrome P450 3A4enzyme
ClindamycinCytochrome P450 3A5enzyme
ClindamycinAlpha-1-acid glycoprotein 1carrier
ClindamycinP-glycoprotein 1transporter
Clindamycin50S ribosomal protein L1target
Clarithromycin50S ribosomal protein L10target
ClarithromycinCytochrome P450 3A4enzyme
ClarithromycinCytochrome P450 3A5enzyme
ClarithromycinP-glycoprotein 1transporter
ClarithromycinSolute carrier family 22 member 7transporter
ClarithromycinPotassium voltage-gated channel subfamily H member 2target
ClarithromycinSolute carrier organic anion transporter family member 1B1target
ClarithromycinSolute carrier organic anion transporter family member 1B3target
ClarithromycinBile salt export pumptransporter
ClarithromycinSolute carrier organic anion transporter family member 1B1transporter
ClarithromycinSolute carrier organic anion transporter family member 1B3transporter
Spiramycin50S ribosomal protein L3target
OleandomycinCytochrome P450 3A4enzyme
SolithromycinCytochrome P450 3A4enzyme