Severe Sepsis (DBCOND0031268)

Identifiers

Synonyms
Sepsis Severe / Sepsis, Severe / Severe sepsis / Severe sepsis without septic shock

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05491941
Assessment for Implementation Methods in SepsisNo drug interventionstreatmentNot Availablerecruiting
NCT06217939
Early Intravenous Hydrocortisone in SepsistreatmentNot Availablerecruiting
NCT05467605
Effect of Probiotics on Cytokines in Sepsis in ChildrenNo drug interventionssupportive_careNot Availablecompleted
NCT04163705
Immune Profile of Patients With SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05975671
Reducing Empiric VAncomycin Use in Pediatric Suspected SepsisNo drug interventionsotherNot Availablerecruiting
NCT04850456
Treatment Strategy of Human Gamma Globulin on the Therapy for Intensively Ill Children With Inflammatory StormNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04105400
Procalcitonin in Diagnosis of Sepsis in Critically Ill PatientNo drug interventionsNot AvailableNot Availableunknown_status
NCT03422159
Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.treatment2completed
NCT03405870
LIPIDS-P Trial Phase I/IItreatment1 / 2recruiting
NCT04796636
High-dose Intravenous Vitamin C in Patients With Septic Shocktreatment1recruiting
NCT06368336
Health Related Quality of Life After Intensive Care for Sepsis, a National Cohort Study.No drug interventionsNot AvailableNot Availablecompleted
NCT04921319
De-resuscitation Informed by Ultrasound for Patients With SepsisNo drug interventionstreatmentNot Availableunknown_status
NCT04134624
EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic ShockNo drug interventionstreatmentNot Availableterminated
NCT03708796
DIAGNOSis of Infection in Emergency DepartmentNo drug interventionsNot AvailableNot Availablecompleted
NCT04508296
The Effect pf Goal-directed De-escalation in ARDS on Organ Function and MortalityNo drug interventionstreatmentNot Availablecompleted
NCT05357339
Microcirculation Properties of Albumin for Fluid Resuscitation in Septic ShockNo drug interventionstreatmentNot Availableunknown_status
NCT02765191
MR-Evaluation of Renal Function In Septic PatientsNo drug interventionsotherNot Availablecompleted
NCT04459572
As an Early Indicator Biomarker of Prognosis and Mortality in Children With Sepsis and Septic Shock: suPARNo drug interventionsdiagnosticNot Availablecompleted
NCT05442710
Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal TherapyNo drug interventionstreatment2recruiting
NCT03884595
Early Identification of Sepsis in ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT03685214
Comparison of Balanced Crystalloids and Normal Saline in Septic PatientstreatmentNot Availableunknown_status
NCT04821414
Effects of IL-1β and Its Receptor Antagonists in the Treatment of Severe Infection and Inflammatory Storm in ChildrenNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03044223
Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa SepsisNo drug interventionsNot AvailableNot Availablerecruiting
NCT05540808
The Value of Full-targeted Pathogen Capture Metagenomics Next Generation Sequencing in Etiological Diagnosis of SepsisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04833621
Is NMES Treatment in Sepsis/ Septic Shock Patients Protective in Development of ICU-AW?No drug interventionssupportive_careNot Availablecompleted
NCT04203979
Sepsis: From Syndrome to Personalized CareNo drug interventionsNot AvailableNot Availablerecruiting
NCT03249597
Predict Sepsis; the Predictive Value of Bedside Measures in the AmbulanceNo drug interventionsNot AvailableNot Availablecompleted
NCT03244293
Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With SepsisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04352985
Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19No drug interventionsNot AvailableNot Availableno_longer_available
NCT04039815
Vitamin C, Vitamin B1 and Steroid in SepsisNo drug interventionstreatment4unknown_status
NCT03802136
Multiple Biomarkers in ICU Sepsis PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03974386
Effects of Endotoxin Absorption and Cytokine Removal Hemofilter on Severe Septic ShockNo drug interventionstreatmentNot Availablecompleted
NCT06178822
Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency RoomNo drug interventionsNot AvailableNot Availablerecruiting
NCT03367026
Reducing Elevated Heart Rate in Patients With Severe Sepsis by IvabradinetreatmentNot Availableunknown_status
NCT04979767
Function of Circulating Exosomes in Sepsis-induced ImmunosuppressionNo drug interventionsNot AvailableNot Availableunknown_status
NCT05836272
Early Administration of Norepinephrine in Sepsistreatment4recruiting
NCT04117568
The Role of Emergency Neutrophils and Glycans in Postoperative and Septic PatientsNo drug interventionsNot AvailableNot Availableterminated
NCT05246969
Detecting Sepsis in Patients With Severe Subarachnoideal HemorrhageNo drug interventionsNot AvailableNot Availablecompleted
NCT04747795
Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departmentstreatment3completed
NCT03821038
Recombinant Interleukin-7 (CYT107) to Restore Absolute Lymphocyte Counts in Sepsis Patientstreatment2terminated
NCT01590303
Outcome Following Vitamin C Administration in Sepsistreatment2unknown_status
NCT02424721
Sepsis Assessment in Belgian Emergency RoomsNo drug interventionsNot AvailableNot Availableterminated
NCT03734484
Gram Type Infection-Specific Sepsis Identification Using Machine LearningNo drug interventionsdiagnostic2withdrawn
NCT01663779
Comparison of Ultrasound-guided Versus Blind Insertion of Radial Artery CathetersNo drug interventionstreatmentNot Availableterminated
NCT05413343
Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill PatientsNot AvailableNot Availablerecruiting
NCT02684487
Vitamin D Status in Patients With Severe Sepsisprevention3withdrawn
NCT00484133
Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsistreatment4unknown_status
NCT03015454
An Algorithm Driven Sepsis Prediction BiomarkerNo drug interventionsscreeningNot Availablecompleted
NCT02960854
A Study of Nivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock.other1completed
NCT01717651
Muscle Atrophy in Patients With Severe SepsisNo drug interventionsNot AvailableNot Availableterminated
NCT03895853
Early Metabolic Resuscitation for Septic ShockNo drug interventionssupportive_care2terminated
NCT01568853
A Prospective Study of The Complement Depletion in Patients With Severe Abdominal SepsisscreeningNot Availablecompleted
NCT01895647
Effect of Different Electric Muscle Stimulation in Patients With Severe Sepsis and Respiratory FailureNo drug interventionspreventionNot Availableterminated
NCT01692847
Examination of the Impact of Better Surveillance and Communication of Patient Deterioration on Patient Related OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT01867905
Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic ShockNo drug interventionsNot AvailableNot Availablecompleted
NCT01945983
Early Use of Norepinephrine in Septic Shock ResuscitationtreatmentNot Availablecompleted
NCT01739361
Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsistreatment2completed
NCT00273728
BaSES Trial: Basel Starch Evaluation in Sepsistreatment4completed
NCT00334828
ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsistreatment3completed
NCT00568893
An Open Label Study of Severe Sepsis in Adultstreatment4completed
NCT03235193
Predictive algoRithm for EValuation and Intervention in SEpsisNo drug interventionsdiagnosticNot Availablecompleted
NCT00148278
Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shocktreatment2 / 3completed
NCT01797978
Methylene Blue in Severe Sepsis and Septic Shocktreatment3unknown_status
NCT02587078
Volume Therapy With Crystalloids and Colloids and Hemodynamic Monitoring in Patients With Severe Sepsistreatment4withdrawn
NCT04353388
Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Washington UniversityNo drug interventionsNot AvailableNot Availablecompleted
NCT01162109
Zinc Therapy in Critical IllnessNo drug interventionsbasic_science1active_not_recruiting
NCT02180009
Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT01858909
Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shocktreatment3unknown_status
NCT06143137
Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow upNo drug interventionsNot AvailableNot Availablerecruiting
NCT02739152
TRIAGE: TRIage of Sepsis At emerGency dEpartmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00449800
Pharmacokinetic of Ceftriaxone in Septic ICU Patientstreatment4unknown_status
NCT00634075
Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsistreatment4completed
NCT02376842
Study of an Electronic Health Record-embedded Severe Sepsis Early Warning AlertNo drug interventionsNot AvailableNot Availablecompleted
NCT01280942
Early Warning System for Clinical Deterioration on General Hospital WardsNo drug interventionspreventionNot Availablecompleted
NCT01211899
4G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic ShockNo drug interventionsNot AvailableNot Availableunknown_status
NCT00398736
A Non-invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients.No drug interventionsNot AvailableNot Availablecompleted
NCT00835913
Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis ImpactNo drug interventionsNot AvailableNot Availablecompleted
NCT04291417
Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Baylor S&WNo drug interventionsNot AvailableNot Availablecompleted
NCT01332734
Microcirculatory Changes During Magnesium Sulphate Infusion in SepsisNot AvailableNot Availablecompleted
NCT01486524
Pharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01144624
A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFab™) in Japanese With Severe Sepsis/Septic ShockNo drug interventionstreatment2completed
NCT01449916
Simplified Severe Sepsis Protocol in ZambiaNo drug interventionstreatmentNot Availableterminated
NCT00819416
Fluid Resuscitation in Early Septic Shocktreatment2completed
NCT02135796
Echocardiography in Septic ShockNo drug interventionsNot AvailableNot Availableunknown_status
NCT01315496
GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic ShockNo drug interventionstreatment3terminated
NCT00709358
Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe InfectionsNo drug interventionsdiagnostic4completed
NCT00510835
Protocolized Care for Early Septic ShockNo drug interventionstreatmentNot Availablecompleted
NCT01724463
Electronic Application of a Severe Sepsis Screening Tool and Management BundleNo drug interventionsNot AvailableNot Availableunknown_status
NCT01474863
Citrulline in Severe Sepsisprevention2completed
NCT02569086
Piperacillin PK Analysis in Severe Sepsis PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00707122
Volume Replacement With Albumin in Severe SepsisNo drug interventionstreatment3completed
NCT03588325
Evaluation of MDW for Early Detection of Sepsis, Clinical ValidityNo drug interventionsNot AvailableNot Availablecompleted
NCT00361725
Comparative Study of the Protein C Pathway in Septic and Non Septic Patients With Organ FailureNo drug interventionsNot AvailableNot Availableterminated
NCT02794025
The Effect of Esmolol on Clinical Prognosis of Patients With Severe SepsistreatmentNot Availablecompleted
NCT00386425
Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)treatment2completed
NCT01319630
The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00837057
Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney InjuryNo drug interventionstreatment4unknown_status
NCT02576457
Safety, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Severe SepsisNo drug interventionstreatment1terminated
NCT01397474
Peripheral Perfusion Targeted Fluid ManagementNo drug interventionssupportive_care4unknown_status
NCT00711620
Efficacy of Thymosin alpha1 for Severe SepsistreatmentNot Availablecompleted
NCT05231720
Mannheim Register of Sepsis and Septic ShockNo drug interventionsNot AvailableNot Availableunknown_status
NCT02903082
Following of Myeloid-derived Suppressor Cells (MDSC) in Severe Sepsis: What Relationship With Systemic Inflammatory Syndrome?No drug interventionsNot AvailableNot Availableterminated
NCT02589431
Comparison of Total, Salivary and Calculated Free Cortisol Levels in Patients With Severe SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT01598831
Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathytreatment3completed
NCT04938531
Targeted Exercise Intervention to Reduce Morbidity and Mortality in SepsisNo drug interventionstreatmentNot Availablecompleted
NCT02346331
Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western KenyaNo drug interventionstreatmentNot Availablecompleted
NCT01556373
Effects of Acute Systemic Inflammation on Arterial Stiffness and Microcirculation.No drug interventionsNot AvailableNot Availablecompleted
NCT02972827
Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic ShockNo drug interventionsdiagnosticNot Availableunknown_status
NCT05048927
Symphony IL-6 Cutoff Validation Study for Patients at Risk of Severe SepsisNo drug interventionsNot AvailableNot Availablerecruiting
NCT03334227
High Flow Nasal Cannula in Severe SepsisNo drug interventionstreatmentNot Availableterminated
NCT03882476
RCT of Sepsis Machine Learning AlgorithmNo drug interventionsdiagnostic2withdrawn
NCT02025660
Efficacy of Mw Vaccine in Treatment of Severe SepsisNo drug interventionstreatment2 / 3completed
NCT03048994
Glutamine Supplementation in Critically Ill Patients With Severe SepsisNo drug interventionstreatmentNot Availablecompleted
NCT00329680
The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of SepsisNo drug interventionstreatment4completed
NCT01371929
Plasma Inducible Nitric Oxide Synthase (iNOS) Assay and Sepsis StudyNo drug interventionsNot AvailableNot Availableterminated
NCT01049529
Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical PatientsNo drug interventionsprevention2completed
NCT03752489
Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal TreatmentNo drug interventionsdiagnostic2unknown_status
NCT02217592
Causes and Factors Associated With Outcomes in Community-acquired Sepsis and Severe Sepsis in Northeast ThailandNo drug interventionsNot AvailableNot Availablecompleted
NCT00207844
Selenium, as Sodium Selenite, in the Treatment of Septic Shocktreatment2completed
NCT02034240
Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis?No drug interventionsNot AvailableNot Availablecompleted
NCT05895240
Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortalityprevention4recruiting
NCT04005001
Machine Learning Sepsis Alert Notification Using Clinical DataNo drug interventionsother2unknown_status
NCT01929772
German Lactat Clearance in Severe SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT03077672
Mitochondrial DNA as a Biomarker of Sepsis SeverityNo drug interventionsNot AvailableNot Availablecompleted
NCT00448968
The Utility of Ischemia Modified Albumin (IMA) in SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT01903746
Epidemiology of Septic Shock in Medical or Polyvalent ICU in the North-East Region of FranceNo drug interventionsNot AvailableNot Availableterminated
NCT00484146
Alterations of Immunologic Mediators During Severe SepsisNo drug interventionsNot AvailableNot Availableterminated
NCT04955210
A Multi-Center Data System and Collaborative Network in China for Severe Infection and Sepsis ChildrenNo drug interventionsNot AvailableNot Availablerecruiting
NCT02871895
Application of Biomarkers Change to Predict Outcome of Patient With Severe SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT02246595
Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunctiontreatment2completed
NCT05060250
Symphony IL-6 Cutoff Establishment Study for Patients at Risk of Severe Sepsis Due to COVID-19No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02734550
(1,3)-β-D-glucan Based Diagnosis of Invasive Candida Infection in SepsisNo drug interventionsdiagnosticNot Availablecompleted
NCT00407823
Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation MonitoringNo drug interventionstreatmentNot Availablecompleted
NCT02899143
Short-course Antimicrobial Therapy in SepsisNo drug interventionstreatment2unknown_status
NCT03960203
Effect of a Sepsis Prediction Algorithm on Clinical OutcomesNo drug interventionsdiagnosticNot Availablecompleted
NCT01654003
Impact of Early Goal-directed Fluid Therapy in Septic Patients Undergoing Emergency SurgeryNo drug interventionspreventionNot Availableterminated
NCT01223690
Clarithromycin as Immunomodulator for the Management of Sepsistreatment3completed
NCT01841190
Prognostic Evaluation Of Severe Sepsis And Septic Shock. Procalcitonin Versus Delta SofaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05296590
Monocyte Distribution Width (MDW) in the General Population of Emergency Department Patients With and Without BacteremiaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01804764
Lotta Alla Sepsi Ospedaliera - Fighting Hospital SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT01449721
Preemptive Resuscitation for Eradication of Septic ShockNo drug interventionstreatmentNot Availablecompleted
NCT00535821
Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic ShockNo drug interventionstreatment4terminated
NCT00372502
Clinical Trial of the Optimal Endpoint of Early Sepsis ResuscitationNo drug interventionstreatmentNot Availablecompleted
NCT02258984
Can the Venus 1000 Help Clinicians Treat Patients With Severe Sepsis or Acute Heart Failure? The CVP TrialNo drug interventionstreatmentNot Availableunknown_status
NCT01273779
Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsistreatment2 / 3suspended
NCT01329887
The Effect of Ketanserin on the Microcirculation in Sepsistreatment3completed
NCT00534287
Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shocktreatment3completed
NCT02655133
Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients.treatment2completed
NCT00670254
Hydrocortisone for Prevention of Septic Shocktreatment3completed
NCT01957254
Investigate the Activity of Endotoxin in Severe SepsisNo drug interventionsNot AvailableNot Availableterminated
NCT05665153
Symphony IL-6 Study in Patients at Risk of Severe SepsisNo drug interventionsNot AvailableNot Availablerecruiting
NCT02664753
L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injurytreatment3recruiting
NCT01943747
International Multicentre Prevalence Study on SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT02539147
Characterization of Non-canonical Way in Inflammasome Monocytes of Patients With Severe SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT00463645
Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02361528
GM-CSF to Decrease ICU Acquired Infectionstreatment3completed
NCT01988428
Prehospital Antibiotics Against Sepsis TrialtreatmentNot Availablecompleted
NCT05304728
Sepsis Clinical Decision Support [CDS] Master Enrollment Study ProtocolNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01806428
Activated Protein C and MicrocirculationNo drug interventionsNot AvailableNot Availablecompleted
NCT00934011
Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe InfectionsNo drug interventionstreatmentNot Availablecompleted
NCT00975793
Australasian Resuscitation In Sepsis Evaluation Randomised Controlled TrialNo drug interventionstreatment3unknown_status
NCT03246893
Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis PatientsNo drug interventionspreventionNot Availablecompleted
NCT00986271
Extravascular Lung Water Index in Severe SepsisNo drug interventionsdiagnosticNot Availablecompleted
NCT00335907
Protocol-driven Hemodynamic Support for Patients With Septic ShockNo drug interventionstreatmentNot Availableunknown_status
NCT00630656
Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsistreatment2completed
NCT02026856
Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe SepsisNot AvailableNot Availablecompleted
NCT00962156
Scandinavian Starch for Severe Sepsis/Septic Shock Trialtreatment3completed
NCT02668432
Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic Shocktreatment4terminated
NCT01284452
Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)treatmentNot Availablecompleted
NCT00159952
Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic ShockNo drug interventionstreatment2 / 3completed
NCT04227652
Control of Fever in Septic PatientstreatmentNot Availablecompleted
NCT02157259
An Observational Study of the Causes, Management, and Outcomes of Community-acquired Sepsis and Severe Sepsis in Southeast AsiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02820675
Quality Improvement in Infection COntrol and Sepsis Management in MOdel RegionsNo drug interventionshealth_services_researchNot Availablecompleted
NCT01312675
S.A.F.E.BT System Extracorporeal Treatment With DIAPACT CRRTNo drug interventionstreatmentNot Availableterminated
NCT00793442
Endothelium in Severe SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT02430142
Microcirculatory Oxygen Uptake in SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT02354742
Echo vs. EGDT in Severe Sepsis and Septic ShockNo drug interventionstreatmentNot Availablecompleted
NCT02777606
The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe SepsisNo drug interventionstreatmentNot Availablecompleted
NCT04804306
Sepsis Post Market Clinical Utility Simple Endpoint Study - HUMCNo drug interventionsNot AvailableNot Availablecompleted
NCT02413541
The Pilot Study of the Efficacy of Polymyxin-B Hemoperfusion in Critically Ill Patients With Severe SepsisNo drug interventionstreatmentNot Availablecompleted
NCT01523717
Procalcitonin Monitoring Sepsis StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00615017
AZD9773 Dose Escalation StudyNo drug interventionstreatment2completed
NCT01337934
Lactated Ringer Versus Albumin in Early Sepsis Therapytreatment3completed
NCT03641534
Monitoring of Perfusion in Sepsis and MalariaNo drug interventionsNot AvailableNot Availablecompleted
NCT01992796
Angiotensin II Antagonist in Severe Sepsistreatment3unknown_status
NCT00167596
Near Infrared Spectroscopy (NIRS) in Severe SepsisNo drug interventionstreatment2 / 3terminated
NCT00772096
Septic Encephalopathy and Late Cognitive Dysfunctionprevention4completed
NCT04819035
Sepsis Post Market Clinical Utility Simple Endpoint Study - Indiana University HospitalNo drug interventionsNot AvailableNot Availablecompleted
NCT01403935
Sepsis Institutional Registry in Hospital Italiano de Buenos AiresNo drug interventionsNot AvailableNot Availablecompleted
NCT02041663
Septic cArdiac Deficiency and MenIngococcal seveRe SepsisNo drug interventionsdiagnosticNot Availablecompleted
NCT02370186
The Role of Dysfunctional HDL in Severe SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT03029039
Platelet-associated Inflammation in Severe SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT00832039
Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsistreatment3completed
NCT01249222
Pro-inflammatory Cytokines Profile and Mortality Rate of Critically Ill Septic Patients Following PlasmapheresisNo drug interventionstreatmentNot Availableunknown_status
NCT03115125
Descriptive Study of the Evolution in Proportion of Regulatory B Lymphocytes in Patients Hospitalized in Intensive Care for Severe SepsisNo drug interventionsotherNot Availableunknown_status
NCT02195830
Inferior Vena Cava Collapsibility Index in Severe SepsisNo drug interventionsdiagnosticNot Availableunknown_status
NCT03655626
Implementation and Evaluations of Sepsis WatchNo drug interventionstreatmentNot Availablecompleted
NCT01314066
Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS)prevention2withdrawn
NCT01493466
Serum Proteomics Analysis for SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT02109965
The Effect of Dexmedetomidine on Microcirculation in Severe Sepsisbasic_science4terminated
NCT02887274
Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT03996720
Early Identification and Effective Management of Pediatric SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT01315782
Alveolar Dead Space as Predictor of Organ Failure in Severe SepsisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04178382
Effect of PCR-CRISPR/Cas12a on the Early Anti-infective Schemes in Patients With Open Air PneumoniaNo drug interventionsdiagnosticNot Availableunknown_status
NCT01352182
Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shocktreatment1 / 2completed
NCT02739373
Pharmacokinetics, Safety, Tolerability and Pharmacodynamics of BMS-986189 in Healthy SubjectsNo drug interventionsbasic_science1completed
NCT00135473
Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)treatment3completed
NCT00541827
Skeletal Muscle and Platelet Mitochondrial Dysfunction During SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT01145560
A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic ShockNo drug interventionstreatment2completed
NCT01025180
Study of Procalcitonin (PCT)-Guided Antibiotic Use in Severe Sepsis Patients Without Obvious InfectionNo drug interventionssupportive_care4terminated
NCT00811629
Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01139489
Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's)No drug interventionstreatmentNot Availablecompleted
NCT01247792
End-of-life Decision-making in Patients With Sepsis-related Organ FailureNo drug interventionshealth_services_researchNot Availablecompleted
NCT03644940
Subpopulation-Specific Sepsis Identification Using Machine LearningNo drug interventionsdiagnostic2withdrawn
NCT01649440
Sepsis MetabolomicsNo drug interventionsNot AvailableNot Availablecompleted
NCT01663701
Simplified Severe Sepsis Protocol-2 (SSSP-2) in ZambiaNo drug interventionstreatmentNot Availablecompleted
NCT01926301
Cerebrovascular Autoregulation in Sepsis, Influence of Renal Replacement TherapyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01378169
SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICUNo drug interventionsNot AvailableNot Availablecompleted
NCT03137446
Restrictive Intravenous Fluids Trial in SepsisNo drug interventionstreatmentNot Availablecompleted
NCT03249246
Epidemiology of Sepsis in Turkish ICUs.No drug interventionsNot AvailableNot Availablecompleted
NCT01968746
The AVERT Sepsis InvestigationNo drug interventionsNot AvailableNot Availablecompleted
NCT01626612
De-escalation of Empirical Antimicrobial Therapy Study in Severe SepsisNo drug interventionstreatment3completed
NCT03141112
The Benefits of Early Initiation of Continual Renal Replacement Therapy in Patients With Severe SepsisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00791310
Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified EtiologyNo drug interventionstreatment3unknown_status
NCT02393781
Adrenomedullin and Outcome in Severe Sepsis and Septic ShockNo drug interventionsNot AvailableNot Availablecompleted
NCT03037281
Release of Nociceptin From Granulocytes in SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT01726595
Ultrasound Measurement of Reactive Hyperemia in Critical CareNo drug interventionsNot AvailableNot Availablecompleted
NCT01932814
Acute Kidney Injury in Septic Critically Ill Patients : Are Aminoglycosides Really Harmful?No drug interventionsNot AvailableNot Availablecompleted
NCT05213923
ED Tracking Sheet ImplementationNo drug interventionstreatmentNot Availablecompleted
NCT01392508
IMproved PREdiction of Severe Sepsis in the Emergency DepartmentNo drug interventionsNot AvailableNot Availablecompleted
NCT01919138
Outcomes of Severe Sepsis Patients in Surgical Intensive Care UnitsNo drug interventionsNot AvailableNot Availablecompleted
NCT02973243
The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study IIINo drug interventionsNot AvailableNot Availablecompleted