NCT02795052
Neurologic Stem Cell Treatment Study No drug interventions treatment Not Available recruiting NCT06120049
[18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DBL vs. AD No drug interventions diagnostic 2 / 3 not_yet_recruiting NCT05696717
Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy treatment 3 recruiting NCT05698017
Study to Evaluate Investigational Allogeneic Cell Therapy Product hOMSC300 for Treatment of Early- to Moderate Stage MSA No drug interventions treatment 1 / 2 recruiting NCT05197816
MotIoN aDaptive Deep Brain Stimulation for MSA No drug interventions treatment Not Available recruiting NCT04753320
Remote Monitoring in Progressive Supranuclear Palsy (PSP) No drug interventions Not Available Not Available recruiting NCT05011773
Manipulating and Optimising Brain Rhythms for Enhancement of Sleep No drug interventions basic_science Not Available completed NCT03577483
Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech Analysis No drug interventions diagnostic Not Available completed NCT05792332
Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study) No drug interventions supportive_care Not Available recruiting NCT05486806
Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement Disorders No drug interventions Not Available Not Available recruiting NCT02194816
Modifiable Variables in Parkinsonism (MVP) No drug interventions Not Available Not Available recruiting NCT04680130
Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders Not Available Not Available enrolling_by_invitation NCT01927055
A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy treatment 3 terminated NCT02388295
AZD3241 PET MSA Trial, Phase 2, Randomized,12 Week Safety and Tolerability Trial With PET in MSA Patients treatment 2 completed NCT06204575
Focused Ultrasound Thalamotomy for Tremor Relief in Atypical Parkinsonism No drug interventions Not Available Not Available completed NCT05923866
A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy No drug interventions treatment 2 recruiting NCT01888185
Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI) No drug interventions Not Available Not Available completed NCT01485549
Oligomeric Alpha-synuclein in Multiple System Atrophy No drug interventions Not Available Not Available completed NCT03811808
Multiple System Atrophy Multidisciplinary Clinic No drug interventions Not Available Not Available recruiting NCT02778607
PROgressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK No drug interventions Not Available Not Available unknown_status NCT04193527
A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients diagnostic 3 completed NCT05086094
Expanded Access Protocol of Verdiperstat in Patients With Multiple System Atrophy (MSA) Not Available Not Available no_longer_available NCT02796209
Norepinephrine Transporter Blockade, Autonomic Failure No drug interventions treatment 2 completed NCT04620382
Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients other 0 recruiting NCT05104476
A Study of Lu AF82422 in Participants With Multiple System Atrophy No drug interventions treatment 2 active_not_recruiting NCT06607900
HUC-MSC-sEV-001 Nasal Drops for Neurodegenerative Diseases No drug interventions treatment 1 not_yet_recruiting NCT05695378
Trial to Evaluate the Efficacy and Safety of KM-819 Treatment to Slow the Progression of Multiple System Atrophy (MSA) No drug interventions treatment 2 terminated NCT06596746
Neurodegenerative Diseases Progression Markers (MARKERS-NDD) No drug interventions Not Available Not Available recruiting NCT06597071
Parkinson Atypical Rating of Oculometric Patterns Evaluated Routinely No drug interventions other Not Available enrolling_by_invitation NCT00465790
Research of Biomarkers in Parkinson Disease No drug interventions Not Available Not Available completed NCT01287221
Study of Rifampicin in Multiple System Atrophy treatment 3 terminated NCT05167721
Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy No drug interventions treatment 2 recruiting NCT02008721
Progression Rate of MSA Under EGCG Supplementation as Anti-Aggregation-Approach treatment 3 completed NCT03872102
Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging No drug interventions Not Available Not Available recruiting NCT03552484
In-Home Care for Patients With PSP and Related Disorders No drug interventions supportive_care Not Available completed NCT04782284
Comprehensive Swallowing Rehabilitation in Patients With MSA No drug interventions treatment Not Available recruiting NCT02185677
Cognitive and Behavioral Dysexecutive Syndrome in Multiple System Atrophy No drug interventions Not Available Not Available completed NCT05638477
Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders No drug interventions diagnostic Not Available recruiting NCT04020198
A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies No drug interventions Not Available Not Available unknown_status NCT03648905
Clinical Laboratory Evaluation of Chronic Autonomic Failure Not Available Not Available active_not_recruiting NCT00103597
Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy treatment 1 completed NCT03482297
Automated Abdominal Binder for Orthostatic Hypotension treatment 1 / 2 recruiting NCT00653783
Diagnostic and Prognostic Biomarkers in Parkinson Disease No drug interventions Not Available Not Available unknown_status NCT02726711
Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic basic_science 1 active_not_recruiting NCT00547911
Augmenting Effects of L-DOPS With Carbidopa and Entacapone treatment 1 / 2 terminated NCT01044693
Nebivolol in the Supine Hypertension of Autonomic Failure Not Available Not Available completed NCT03076671
More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease No drug interventions treatment Not Available completed NCT03446807
Safety and Efficacy of Droxidopa for Fatigue in Patients With Parkinsonism treatment 2 withdrawn NCT03452956
Cognitive Impairement In Frontotemporal Dementia No drug interventions Not Available Not Available completed NCT02417415
Local Heat Stress in Autonomic Failure Patients With Supine Hypertension No drug interventions other Not Available completed NCT05638815
An Observational Study of Parkinson's Disease and Other Synucleinopathies (EASE-PD) No drug interventions Not Available Not Available completed NCT06209515
Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study No drug interventions Not Available Not Available active_not_recruiting NCT04246437
[18F]F-DOPA Imaging in Patients With Autonomic Failure basic_science 1 recruiting NCT04518059
Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism No drug interventions Not Available Not Available recruiting NCT02071459
Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA treatment 2 / 3 completed NCT05489575
CPAP for the Treatment of Supine Hypertension No drug interventions treatment Not Available recruiting NCT05139342
Evaluation of the Efficacy of a Two-week EMST on Dysphagia in Parkinsonian Patients No drug interventions treatment Not Available recruiting NCT03952806
Study of BHV-3241 in Participants With Multiple System Atrophy treatment 3 completed NCT00758849
Fipamezole in Neurogenic Orthostatic Hypotension treatment 2 unknown_status NCT00001549
Diagnosis and Natural History Study of Patients With Neurological Conditions No drug interventions Not Available Not Available completed NCT03120013
Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia No drug interventions treatment Not Available completed NCT01136213
Investigation of the Serotoninergic System in Multiple System Atrophy: a Positron Emission Tomography (PET) Study No drug interventions Not Available Not Available completed NCT00822913
Botulinum A Toxin in Patients With Parkinson's Disease treatment 4 unknown_status NCT04468919
Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit No drug interventions basic_science Not Available recruiting NCT02994719
Gait Analysis in Neurological Disease Not Available Not Available recruiting NCT01119417
The Role of Endothelin in the Supine Hypertension of Autonomic Failure other 1 withdrawn NCT04706234
Systematic Assessment of Laryngopharyngeal Function in Patients With MSA, PD, and 4repeat Tauopathies No drug interventions Not Available Not Available recruiting NCT00742586
Autonomic Failure Patients for RNA Blood Sampling No drug interventions Not Available Not Available completed NCT05222386
Community Outreach for Palliative Engagement -- Parkinson Disease No drug interventions treatment Not Available recruiting NCT02640339
Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease No drug interventions Not Available Not Available completed NCT04700722
Synuclein-One Study No drug interventions Not Available Not Available completed NCT04965922
Quality of Life of Caregivers and Patients Suffering From Multiple System Atrophy No drug interventions supportive_care Not Available unknown_status NCT04313530
TMS Treatment in Multiple System Atrophy With Fatigue No drug interventions treatment Not Available unknown_status NCT04472130
Neurodegenerative Diseases Registry No drug interventions Not Available Not Available unknown_status NCT06174948
The Use of the CUE1 in People With Parkinson's Disease and Related Disorders No drug interventions treatment Not Available not_yet_recruiting NCT02429557
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure other 1 recruiting NCT05819957
Therapeutic Education for Multiple System Atrophy (MSA) Patients and Their Caregivers No drug interventions diagnostic Not Available recruiting NCT02064166
Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin. treatment 2 completed NCT01316666
Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension No drug interventions Not Available Not Available completed NCT00977665
Clinical Trial to Assess Efficacy, Safety, and Tolerability of Rasagiline Mesylate 1 mg in Patients With Multiple System Atrophy of the Parkinsonian Subtype (MSA-P) treatment 2 completed NCT04495582
Long-term Follow-up of Phase 1 Clinical Trial of CS10BR05(CS10BR05-MSA101) No drug interventions Not Available Not Available active_not_recruiting NCT03589976
A Futility Trial of Sirolimus in Multiple System Atrophy treatment 2 terminated NCT05634876
UB-312 in Patients With Synucleinopathies No drug interventions treatment 1 / 2 active_not_recruiting NCT05889260
Speech Accessibility Project No drug interventions Not Available Not Available recruiting NCT05526391
A Study of TAK-341 in Treatment of Multiple System Atrophy No drug interventions treatment 2 active_not_recruiting NCT05109091
Study of ATH434 in Participants With Multiple System Atrophy treatment 2 active_not_recruiting NCT02270489
Study Assessing Safety and Therapeutic Activity of AFFITOPE® PD01A and PD03A in Patients With Early MSA No drug interventions treatment 1 completed NCT01577992
Evaluation of the Subjective and Objective Painful Threshold in Multiple System Atrophy Pain and Multiple System Atrophy basic_science Not Available completed NCT04450992
TRACK-MSA: A Longitudinal Study to Define Outcome Measures in Multiple System Atrophy No drug interventions Not Available Not Available completed NCT06221644
Synapse Alterations in MSA Patients No drug interventions Not Available Not Available completed NCT03265444
Safety and Tolerability of CS10BR05 Inj. in Subjects With Multiple System Atrophy No drug interventions treatment 1 completed NCT03269201
Brain Network Activation in Patients With Movement Disorders No drug interventions Not Available Not Available unknown_status NCT02149901
Water and Sudafed in Autonomic Failure other 0 terminated NCT00997672
Lithium in Multiple System Atrophy treatment 2 terminated NCT02445469
Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Syndromes No drug interventions diagnostic Not Available terminated NCT04153110
Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia No drug interventions treatment Not Available completed NCT03174938
The Swedish BioFINDER 2 Study No drug interventions diagnostic Not Available recruiting NCT03901638
Tllsh2910 for Ataxia and Gut Microbiota Alteration in Patients of Multiple System Atrophy No drug interventions treatment 3 terminated NCT03721887
Exploit the Neural Source and the Feasibility of Transcranial Direct Current Stimulation for Freezing of Gait in Parkinson's Disease and Multiple System Atrophy No drug interventions treatment Not Available unknown_status NCT05238545
The Effect of Gluten-free Diet on Parkinsonism No drug interventions treatment Not Available recruiting NCT06072105
Medical Decision Making in Multiple System Atrophy No drug interventions supportive_care Not Available recruiting NCT05171205
Spinal Cord Stimulation for Multiple System Atrophy No drug interventions treatment Not Available recruiting NCT01353183
Analysis of the Enteric Nervous System Using Colonic Biopsies No drug interventions diagnostic Not Available completed NCT00743561
Assessment of Ambulatory Polygraphy in the Detection of Sleep Apnea in Multiple System Atrophy (SAMSA) No drug interventions diagnostic Not Available completed NCT05748028
Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms No drug interventions Not Available Not Available recruiting NCT04250493
Insulin Resistance in Multiple System Atrophy health_services_research Not Available unknown_status NCT04858893
Application of Machine Learning Method in Validation of Screening Cognitive Test for Parkinsonisms No drug interventions Not Available Not Available completed NCT03042988
Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension No drug interventions treatment Not Available recruiting NCT02761707
Biomarkers in Neural Disorders No drug interventions Not Available Not Available completed NCT03403309
Inosine 5'-Monophosphate to Raise of Serum Uric Acid Level in Patients With Multiple System Atrophy: a Multi-center, Randomized Controlled, Double Blind, Parallel Assigned Clinical Trial treatment 2 completed NCT04616456
Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients treatment 0 completed NCT01799915
Natural History Study of Synucleinopathies No drug interventions Not Available Not Available recruiting NCT06568237
A Study to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy Safety and Efficacy Study No drug interventions treatment 2 recruiting NCT02132052
Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders (PD), Essential Tremor (ET), Cortical Basal Degeneration (CBD), Multiple Systems Atrophy (MSA), Magnetoencephalography. No drug interventions Not Available Not Available completed NCT05621200
Transcranial Alternating Current Stimulation (tACS) in Patients With Ataxia No drug interventions treatment Not Available completed NCT04287270
Respiratoy Muscle Strength in Patients With Multiple System Atrophy No drug interventions health_services_research Not Available completed NCT02114242
Biomarkers in Parkinsonian Syndromes No drug interventions Not Available Not Available recruiting NCT00368199
Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes No drug interventions Not Available Not Available completed NCT06203106
NYSCF Scientific Discovery Biobank No drug interventions Not Available Not Available recruiting NCT04431713
Exenatide Once-weekly as a Treatment for Multiple System Atrophy treatment 2 unknown_status NCT06162013
The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism No drug interventions treatment 2 recruiting NCT00211224
Neuroprotection and Natural History in Parkinson's Plus Syndromes (NNIPPS) treatment 3 terminated NCT02428816
Evaluation of a Multimodal Neuroimaging Method for Diagnosis in Parkinsonian Syndromes No drug interventions diagnostic Not Available completed NCT05453058
Observational Study in Multiple System Atrophy No drug interventions Not Available Not Available completed NCT02897063
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure basic_science 1 recruiting NCT04184063
Study of NBMI Treatment in Patients With Atypical Parkinsons (PSP or MSA) No drug interventions treatment 2 completed NCT03753763
Safinamide for Multiple System Atrophy (MSA) treatment 2 completed NCT04165486
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON) No drug interventions treatment 1 recruiting NCT04782830
Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms other Not Available recruiting NCT01146548
Fluoxetine in Multiple System Atrophy Patients supportive_care 2 completed NCT05826457
North American Prodromal Synucleinopathy Consortium Stage 2 No drug interventions Not Available Not Available recruiting NCT04876326
Potential Use of Autologous and Allogeneic Mesenchymal Stem Cells in Patients With Multiple System Atrophy No drug interventions treatment Not Available unknown_status NCT06490926
NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome No drug interventions Not Available Not Available recruiting NCT00911365
Trial of Autologous Mesenchymal Stem Cells in Patients With Multiple System Atrophy No drug interventions treatment 2 completed NCT05864365
Biomarker Study of ATH434 in Participants With MSA No drug interventions treatment 2 active_not_recruiting NCT04680065
GDNF Gene Therapy for Multiple System Atrophy No drug interventions treatment 1 recruiting NCT04229173
Natural History and Disease Progression Biomarkers of Multiple System Atrophy No drug interventions other Not Available completed NCT05807373
Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech Analysis - Part 2 No drug interventions diagnostic Not Available recruiting NCT04844060
Cerebro Spinal Fluid Collection (CSF) No drug interventions Not Available Not Available recruiting NCT05699460
Pre-Gene Therapy Study in Parkinson's Disease and Multiple System Atrophy No drug interventions Not Available Not Available active_not_recruiting NCT01292694
Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure basic_science 1 terminated NCT00738062
Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) treatment 3 completed NCT05067192
Optimization of Morphomer-based Alpha-synuclein PET Tracers No drug interventions Not Available Not Available completed NCT01155492
Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease No drug interventions Not Available Not Available completed NCT00750867
Treatment of Multiple System Atrophy Using Intravenous Immunoglobulins treatment 2 completed NCT03623672
North American Prodromal Synucleinopathy Consortium No drug interventions Not Available Not Available unknown_status NCT01607268
Magnetic Resonance Spectroscopy in Autonomic Failure No drug interventions Not Available Not Available terminated NCT01793168
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford No drug interventions Not Available Not Available recruiting NCT06501469
Biomarkers in Parkinsonian Syndromes No drug interventions Not Available Not Available recruiting NCT03593512
Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System Atrophy No drug interventions treatment Not Available completed NCT05121012
Synaptic Loss in Multiple System Atrophy No drug interventions Not Available Not Available recruiting NCT06098612
PET Imaging Evaluation of [11C]SY08 basic_science 0 recruiting NCT03924414
Trial of Parkinson's And Zoledronic Acid treatment 4 recruiting NCT05732415
Biomarker Study of ATH434 in Participants With MSA No drug interventions treatment 2 not_yet_recruiting