Unresectable Solid Tumor (DBCOND0140202)

Identifiers

Synonyms
Unresectable Solid Neoplasm / Unresectable Solid Tumors

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Dabrafenib
A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02535312
Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatintreatment1 / 2active_not_recruiting
NCT03218826
PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgerytreatment1active_not_recruiting
NCT01638533
Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunctiontreatment1active_not_recruiting
NCT02097225
Onalespib, Dabrafenib, and Trametinib in Treating Patients With BRAF-Mutant Melanoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgerytreatment1terminated
NCT02721732
Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatictreatment2active_not_recruiting
NCT03087591
APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by SurgeryNo drug interventionstreatment1completed
NCT04957615
Nivolumab for the Treatment of Metastatic or Unresectable Solid Tumors With ARID1A Mutation and CXCL13 Expressiontreatment2recruiting
NCT03366103
Navitoclax and Vistusertib in Treating Patients With Relapsed Small Cell Lung Cancer and Other Solid Tumorstreatment1 / 2terminated
NCT00576654
Veliparib and Irinotecan Hydrochloride in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgerytreatment1active_not_recruiting
NCT03217253
Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunctiontreatment1withdrawn
NCT02503709
Onalespib and CDKI AT7519 in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgerytreatment1active_not_recruiting
NCT02070549
Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunctiontreatment1active_not_recruiting
NCT03326258
Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgerytreatment1 / 2withdrawn
NCT02432963
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapytreatment1active_not_recruiting
NCT01738139
Ipilimumab and Imatinib Mesylate in Advanced Cancertreatment1completed
NCT01822522
Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virustreatment1completed
NCT02143401
Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumorstreatment1active_not_recruiting
NCT03291938
IACS-010759 in Advanced CancersNo drug interventionstreatment1completed
NCT04250597
Study of GNX102 in Patients With Advanced Solid TumorsNo drug interventionstreatment1terminated
NCT02408861
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgerytreatment1recruiting
NCT03229278
Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphomatreatment1completed
NCT03061188
Phase I/Ib Study of Nivolumab & Veliparib in Patients With Advanced Solid Tumors & Lymphomatreatment1completed
NCT01787500
Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgerytreatment1active_not_recruiting
NCT01012817
Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancertreatment1 / 2active_not_recruiting
NCT02159989
Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgerytreatment1completed
NCT06244771
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT05216432
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, As a Single Agent in Advanced Solid Tumor Patients and in Combination with Fulvestrant in Patients with Advanced Breast Cancertreatment1recruiting
NCT06302621
Pemigatinib + Afatinib in Advanced Refractory Solid Tumorstreatment1recruiting
NCT04914117
A Study of RC118 in Patients With Locally Advanced Unresectable/Metastatic Solid Tumourstreatment1completed
NCT06184035
A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancertreatment1 / 2recruiting
NCT05086692
A Beta-only IL-2 ImmunoTherapY Studytreatment1 / 2recruiting
NCT05461664
Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRANo drug interventionsNot AvailableNot Availableunknown_status
NCT05831579
Palliative Spatially Fractionated (GRID) Radiotherapy Using Intensity Modulated Proton TherapyNo drug interventionstreatmentNot Availablerecruiting
NCT06185556
COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver MetastasesNo drug interventionstreatment2 / 3recruiting
NCT05464875
A Multicenter Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal TumorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05759949
First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumorstreatment1active_not_recruiting
NCT04572451
Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanomatreatment1recruiting