| Fluoxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. |
| Zafirlukast | A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. |
| Tamoxifen | A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women. |
| Suprofen | An NSAID used to prevent pupil constriction in ocular surgery. |
| Metronidazole | A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. |
| Sulfamethoxazole | An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. |
| Fluvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| Sertraline | A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. |
| Phenytoin | An anticonvulsant drug used in the prophylaxis and control of various types of seizures. |
| Lansoprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Glyburide | A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. |
| Ginkgo biloba | Appears to be effective in: alleviating age-related memory impairment in some elderly people with mild to moderate age-related memory or cognitive impairment; improving cognitive function in healthy young to middle-aged... |
| Avasimibe | Investigated for use/treatment in peripheral vascular disease. |
| Lovastatin | An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke. |
| Simvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. |
| Cerivastatin | A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. |
| Imatinib | A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. |
| Paroxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. |
| Valsartan | An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors. |
| Bortezomib | A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. |
| Nevirapine | A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. |
| Azelastine | A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. |
| Fenofibrate | A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. |
| Phenylbutazone | An NSAID used to treat backache and ankylosing spondylitis. |
| Teniposide | A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia. |
| Etravirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. |
| Sulfadiazine | A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. |
| Sulfisoxazole | A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. |
| Leflunomide | A pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis. |
| Nilotinib | A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib. |
| Sitaxentan | Investigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure. |
| Tranylcypromine | A monoamine oxidase inhibitor used to treat major depressive disorder. |
| Clopidogrel | An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. |
| Etoricoxib | For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. |
| Sulfamoxole | For the treatment of bacterial infection. |
| Amodiaquine | For treatment of acute malarial attacks in non-immune subjects. |
| Anastrozole | A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women. |
| Atovaquone | An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. |
| Cimetidine | A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. |
| Cyclizine | An antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo. |
| Epinephrine | A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. |
| Ethanol | For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical... |
| Felodipine | A calcium channel blocker used to treat hypertension. |
| Flecainide | A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). |
| Medroxyprogesterone acetate | A progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty. |
| Modafinil | A stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder. |
| Nilutamide | An antineoplastic hormone used to treat prostate cancer. |
| Pranlukast | Used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. |
| Promethazine | A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. |
| Sulfamethizole | A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. |
| Sulfapyridine | A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. |
| Tolcapone | A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. |
| Bicalutamide | An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate. |
| Rabeprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Armodafinil | A stimulant used to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea, narcolepsy, or shift work disorder. |
| Diethylstilbestrol | Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery. |
| Agomelatine | Agomelatine is indicated to treat major depressive episodes in adults. |
| Noscapine | Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma. |
| Clevidipine | A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. |
| Cisplatin | A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. |
| Sulconazole | A topical antifungal agent used for the treatment of tinea cruris, tinea corporis, and tinea versicolor caused by susceptible fungal strains. |
| Vismodegib | A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. |
| Gefitinib | A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria. |
| Ceritinib | An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib. |
| Belinostat | A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). |
| Lifitegrast | A medication used to treat dry eye disease. |
| Diacerein | For the treatment of osteoarthritis affecting the hip or knee . |
| Doconexent | An omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. |
| Topiroxostat | Indicated for the treatment of gout and hyperurcemia in Japan. |
| Stiripentol | An anticonvulsant agent used with clobazam and valproate as an adjunct to treat refractory generalized tonic-clonic seizures in Dravet syndrome. |
| Lobeglitazone | Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use... |
| Dosulepin | Indicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required. |
| Manidipine | For the treatment of hypertension. |
| Enasidenib | An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. |
| Rucaparib | An anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer. |
| Isavuconazole | Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label].
Indicated for patients 18 years of age and older for the treatment of... |
| Black cohosh | Treatment of menopausal symptoms and menstrual dysfunction . |
| Genistein | Currently Genistein is being studied in clinical trials as a treatment for prostate cancer. |
| Lenvatinib | A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. |
| Vemurafenib | A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. |
| Fluorouracil | A pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment. |
| Midostaurin | An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). |
| Atorvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| Sulfaphenazole | For the treatment bacterial infections. |
| Sulfadimethoxine | For use in the treatment of infections. |
| Methimazole | A thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism. |
| Isoniazid | An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. |
| Ketoprofen | An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain. |
| Estrone sulfate | An estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders. |
| Benzbromarone | Benzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia. |
| Seproxetine | Seproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an... |
| Oxandrolone | An androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis. |
| Rifamycin | An antibacterial used to treat traveler's diarrhea. |
| Torasemide | A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. |
| Triclabendazole | An anthelmintic drug used to treat fascioliasis. |
| Progesterone | A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. |
| Pexidartinib | An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. |
| Probenecid | A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia. |
| Nicardipine | A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. |
| Aprepitant | A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. |
| Levofloxacin | A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. |
| Cisapride | A medication used to treat heartburn associated with GERD. |
| Dexloxiglumide | For the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD). |
| Tienilic acid | For the treatment of hypertension. |
| Curcumin sulfate | No approved therapeutic indications. |
| Regorafenib | A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma. |
| Lumacaftor | A protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene. |
| Abemaciclib | A medication used to treat HR+ HER2- advanced or metastatic breast cancer. |
| Atazanavir | An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. |
| Elexacaftor | A small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation. |
| Nifedipine | A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. |
| Methylene blue | An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia. |
| Pralsetinib | A RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer. |
| Opicapone | A catechol-O-methyltransferase inhibitor used as an adjunct treatment for Parkinson's Disease in adults currently receiving levodopa and a dopa decarboxylase inhibitor. |
| Menadione | The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. |
| Rilpivirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). |
| Casimersen | An antisense phosphorodiamidate morpholino oligonucleotide used to treat Duchenne muscular dystrophy patients with mutations amenable to exon 45 skipping. |