Microsatellite Instability-high (MSI-H)

Also known as: High-Frequency Microsatellite Instability / High microsatellite instability / Microsatellite Instability-High / MSI-High / MSI-H / Microsatellite Instability High / Microsatellite Instability - High (MSI-H) / Microsatellite instability cancer

DrugDrug NameDrug Description
DB09078LenvatinibA receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
DrugDrug NameTargetType
DB09078LenvatinibVascular endothelial growth factor receptor 1target
DB09078LenvatinibVascular endothelial growth factor receptor 2target
DB09078LenvatinibVascular endothelial growth factor receptor 3target
DB09078LenvatinibFibroblast growth factor receptor 1target
DB09078LenvatinibFibroblast growth factor receptor 2target
DB09078LenvatinibFibroblast growth factor receptor 3target
DB09078LenvatinibFibroblast growth factor receptor 4target
DB09078LenvatinibPlatelet-derived growth factor receptor alphatarget
DB09078LenvatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB09078LenvatinibMast/stem cell growth factor receptor Kittarget
DB09078LenvatinibP-glycoprotein 1transporter
DB09078LenvatinibATP-binding cassette sub-family G member 2transporter
DB09078LenvatinibCytochrome P450 3A4enzyme
DB09078LenvatinibAldehyde oxidaseenzyme
DB09078LenvatinibCytochrome P450 2C8enzyme
DB09078LenvatinibCytochrome P450 2C9enzyme
DB09078LenvatinibCytochrome P450 1A2enzyme
DB09078LenvatinibCytochrome P450 2B6enzyme
DB09078LenvatinibCytochrome P450 2C19enzyme
DB09078LenvatinibSolute carrier family 22 member 6transporter
DB09078LenvatinibSolute carrier family 22 member 8transporter
DB09078LenvatinibSolute carrier family 22 member 2transporter
DB09078LenvatinibSolute carrier organic anion transporter family member 1B1transporter
DB09078LenvatinibBile salt export pumptransporter
DB09078LenvatinibCytochrome P450 2D6enzyme
DB09078LenvatinibSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB17293Hiltonol1Active Not Recruiting1
DB06186Ipilimumab1Recruiting1
DB17480Nanrilkefusp alfa1Active Not Recruiting1
DB09035Nivolumab1Recruiting1
DB09037Pembrolizumab1Active Not Recruiting1
DB09037Pembrolizumab1Completed1
DB09037Pembrolizumab1Recruiting1
DB16413Sotigalimab1Completed1
DB15387Bintrafusp alfa1 / 2Active Not Recruiting1
DB16680Cadonilimab1 / 2Recruiting1
DB06186Ipilimumab1 / 2Recruiting1
DB09035Nivolumab1 / 2Recruiting1
DB08935Obinutuzumab1 / 2Recruiting1
DB09037Pembrolizumab1 / 2Recruiting2
DB15765Sintilimab1 / 2Recruiting1
DB16680Cadonilimab2Not Yet Recruiting1
DB14776Camrelizumab2Active Not Recruiting1
DB00482Celecoxib2Recruiting1
DB00531Cyclophosphamide2Active Not Recruiting1
DB17743Fecal microbiota2Recruiting1
DB09037Pembrolizumab2Active Not Recruiting1
DB14765Rivoceranib2Active Not Recruiting1
DB15043Toripalimab2Recruiting1
DB15676Balstilimab3Not Yet Recruiting1
DB16651Botensilimab3Not Yet Recruiting1
DB09035Nivolumab3Not Yet Recruiting1
DB15765Sintilimab3Recruiting1
DB15769EnvafolimabNot AvailableNot Yet Recruiting1