Protein Kinase C, antagonists & inhibitors

Protein Kinase C, antagonists & inhibitors
Accession Number

Not Available

DrugDrug Description
7-HydroxystaurosporineNot Available
K-252aNot Available
DebromohymenialdisineNot Available
AprinocarsenInvestigated for use/treatment in lung cancer.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
RuboxistaurinRuboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus.
SafingolSafingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Bisindolylmaleimide VIIINot Available
Bisindolylmaleimide INot Available
ChelerythrineA benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
Go-6976An inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
Drugs & Drug Targets
7-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
K-252aHepatocyte growth factor receptortarget
K-252aDual specificity mitogen-activated protein kinase kinase 1target
DebromohymenialdisineActivated CDC42 kinase 1target
DebromohymenialdisineDual specificity protein kinase CLK1target
AprinocarsenProtein kinase C alpha typetarget
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
Bisindolylmaleimide VIII3-phosphoinositide-dependent protein kinase 1target
Bisindolylmaleimide VIIIMyotonin-protein kinasetarget
Bisindolylmaleimide ISerine/threonine-protein kinase pim-1target
Bisindolylmaleimide I3-phosphoinositide-dependent protein kinase 1target
Bisindolylmaleimide IProtein kinase C iota typetarget