NCT05513313
Assessment of Myocarditis After Replication-Deficient Smallpox Immunization Not Available Not Available not_yet_recruiting NCT00879762
High Dose IMVAMUNE® in Vaccinia-Naive Individuals prevention 2 completed NCT00565929
Safety, Reactogenicity and Immunogenicity of MVA in Hematopoietic Stem Cell Transplant (HSCT) Subjects prevention 1 completed NCT00928577
Safety Surveillance Cohort Study of Vaccinia Vaccine (ACAM2000®) No drug interventions Not Available Not Available completed NCT00258947
Evaluation of Take and Safety of a Smallpox Vaccine in Healthy Young Adults prevention 2 completed NCT04971109
Safety, Tolerability and Pharmacokinetics of TPOXX When Administered Orally for 28 Days treatment 3 completed NCT00063856
Dressing Preparations for Smallpox No drug interventions prevention 1 / 2 completed NCT01144637
A Trial to Evaluate Immunogenicity and Safety of Three Consecutive Production Lots of IMVAMUNE® (MVA-BN®) Smallpox Vaccine in Healthy, Vaccinia-naïve Subjects prevention 3 completed NCT01668537
A Phase II Trial to Compare a Liquid-frozen and a Freeze-dried Formulation of IMVAMUNE (MVA-BN®) Smallpox Vaccine in Vaccinia-naïve Healthy Subjects prevention 2 completed NCT00914732
Lyophilized IMVAMUNE® (1x10^8 TCID50) Versus Liquid IMVAMUNE® (1x10^8 TCID50) Administered Subcutaneously and a Lower Dose Liquid IMVAMUNE® (2x10^7 TCID50) Administered Intradermally prevention 2 completed NCT05976100
Study of the Safety, Tolerability, Pharmacokinetics of NIOCH-14 in Volunteers Aged 18-50 Years No drug interventions treatment 1 completed NCT05995275
A Study to Investigate The Safety, Tolerability, And Immune Response of a Range of Doses of mRNA-1769 Compared With Placebo in Healthy Participants From ≥18 Years of Age to <50 Years of Age No drug interventions prevention 1 / 2 active_not_recruiting NCT00133575
ACAM 3000 MVA at Harvard Medical School prevention 1 / 2 completed NCT01056770
Safety and Efficacy of CJ Smallpox Vaccine in Healthy Volunteers prevention 3 completed NCT00927719
Safety Surveillance Study of ACAM2000® Vaccinia Vaccine Not Available Not Available completed NCT03699124
Freeze-Dried MVA-BN® Lot Consistency Smallpox Trial prevention 3 completed NCT00123396
VHA Clinicians and Bioterror Events: Interactive Web-based Learning No drug interventions Not Available Not Available completed NCT04392739
Safety, Tolerability and PK of TPOXX in Adults Weighing More Than 120 KG other 4 completed NCT00686582
An Open-Label Phase II Study to Evaluate Immunogenicity and Safety of a Single IMVAMUNE Booster Vaccination Two Years After the Last IMVAMUNE Vaccination in Former POX-MVA-005 Vaccinees prevention 2 completed NCT00053482
Dose Study of ACAM2000 Smallpox Vaccine in Previously Vaccinated Adults prevention 2 completed NCT01540929
Post-licensure Department of Defense (DOD) Screening Accuracy Study in Military Personnel No drug interventions Not Available Not Available completed NCT00728689
Phase I Trial of an Investigational Small Pox Medication treatment 1 completed NCT02474589
A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of the Anti-Orthopoxvirus Compound Tecovirimat treatment 3 completed NCT02038881
Randomized, Open-label Phase II Trial to Assess the Safety and Immunogenicity of MVA-BN Smallpox Vaccine in Immunocompromised Subjects With HIV Infection prevention 2 completed NCT00032708
Dryvax Dilution-Prev Vacc Adults No drug interventions prevention 2 completed NCT01317238
Safety and Efficacy of CJ Smallpox Vaccine in Previously Vaccinated Healthy Volunteers prevention 3 completed NCT05846243
Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years prevention 2 / 3 completed NCT00038987
Vaccinia Virus Vaccine (APSV) in Vaccinia- Naive Subjects: PILOT No drug interventions prevention 1 / 2 completed NCT00466245
Phase 2 Study of Safety, Tolerability, and Immunogenicity of Three Dose Levels of ACAM3000 Smallpox Vaccine prevention 2 completed NCT00068198
Human Immune Responses Smallpox No drug interventions prevention 1 completed NCT00050505
Expanded Dryvax Dilution Study in Previously Vaccinated Adults prevention 2 completed NCT00026611
A Study of Dryvax Vaccine Against Smallpox in Previously Unvaccinated Adults No drug interventions prevention 2 completed NCT03972111
A Phase 4, Observational Field Study to Evaluate TPOXX in Patients With Smallpox Not Available Not Available withdrawn NCT00857493
A Study to Evaluate Safety and Immunogenicity of One and Two Doses of IMVAMUNE® Smallpox Vaccine in 56-80 Year Old Vaccinia-experienced Subjects prevention 2 completed NCT01827371
Phase II Trial to Assess Safety and Immunogenicity of IMVAMUNE® prevention 2 completed NCT00189956
Dose-finding Study to Evaluate Immunogenicity of Three Different Dose Levels of the IMVAMUNE (MVA-BN) Smallpox Vaccine. prevention 2 completed NCT04957485
Study to Assess the Safety and Pharmacokinetics of TPOXX® When Administered Orally for 28 Days With JYNNEOS treatment 2 completed NCT00646152
Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study treatment 1 completed NCT00050518
APSV in Vaccinia Naive Adults prevention 2 completed NCT05935917
Study Evaluating the Bioequivalence of Brincidofovir Form H and Form II Tablets in Healthy Adults treatment 1 completed NCT00316524
A Randomized, Double-blind, Placebo-controlled Study on Immunogenicity and Safety of MVA-BN (IMVAMUNE™) Smallpox Vaccine in Healthy Subjects prevention 2 completed NCT00336635
Safety and Immunogenicity of CJ-50300 prevention 1 completed NCT04485039
Drug-drug Interaction Study of TPOXX When Co-administered With Phosphate Binders other 4 completed NCT00079820
Safety, Tolerability, and Immune Response of ACAM3000 Modified Vaccinia Ankara (MVA) Smallpox Vaccine in Adults prevention 1 completed NCT00042094
Study of Reactogenicity, Safety, Immunogenicity, and Pock Lesion Formation of a Cell-Cultured Smallpox Vaccine Compared to Dryvax® prevention 1 completed NCT02080767
Tecovirimat (ST-246) Treatment for Orthopox Virus Exposure Not Available Not Available available NCT00189969
Take Rate, Immunogenicity and Safety of Elstree-BN Smallpox Vaccine in Healthy Vaccinia-Naive Subjects No drug interventions prevention 1 completed NCT00082446
Combination Study With MVA BN and Dryvax prevention 1 completed NCT00282581
Safety Study of MVA Smallpox Vaccine in HIV-positive Subjects Who Are Vaccinia Naive prevention 1 terminated NCT00053495
Effect of Dose, Safety, Tolerability of a New Smallpox Vaccine in Adults Without Previous Smallpox Vaccination prevention 2 completed NCT05762523
Safety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 Years prevention 1 completed NCT00053508
Dose Safety, Tolerability, and Immunogenicity of a New Smallpox Vaccine in Adults Without Previous Smallpox Vaccination prevention 2 terminated NCT00998543
A Long-Term Study of Healthy Adults Vaccinated With One Dose of Smallpox Vaccine (LISTER Strain) No drug interventions Not Available Not Available completed NCT00189943
Study on Safety, Tolerability and Immunogenicity of an MVA Vaccine Administered to Healthy Subjects prevention 1 completed NCT00607243
Safety and Efficacy of CJ-50300 in Healthy Volunteers prevention 2 / 3 completed NCT00389103
Safety Study of MVA Smallpox Vaccine in Subjects With a History of Atopic Dermatitis (AD) prevention 1 withdrawn NCT00437021
MVA Post-Event: Administration Timing and Boost Study prevention 1 / 2 completed NCT00103584
Safety and Immunogenicity Study of LC16m8, a Modified Smallpox Vaccine, in Healthy, Previously Unvaccinated Volunteers prevention 1 / 2 unknown_status