Maintenance of anesthesia therapy (DBCOND0024393)

Identifiers

Synonyms

Maintenance of anesthesia / Maintenance of anaesthesia / Anaesthetic maintenance / Anesthetic maintenance

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Alfentanil	An opioid agonist used to induce and maintain anesthesia, as well as an analgesic.	Mu-type opioid receptortarget Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme Alpha-1-acid glycoprotein 1carrier Albumincarrier Cytochrome P450 3A7enzyme ATP-dependent translocase ABCB1transporter
Desflurane	A general inhalation anesthetic for inpatient and outpatient surgery in adults.	NADH-ubiquinone oxidoreductase chain 1target Glycine receptor subunit alpha-1target Glutamate receptor 1target GABA(A) Receptortarget Potassium voltage-gated channel subfamily A member 1target ATP synthase subunit delta, mitochondrialtarget Albumincarrier Calcium transporting ATPasestarget Cytochrome P450 2E1enzyme
Fentanyl	An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management.	Mu-type opioid receptortarget Delta-type opioid receptortarget Cytochrome P450 3A4enzyme Cytochrome P450 3A7enzyme ATP-dependent translocase ABCB1transporter Kappa-type opioid receptortarget ATP-dependent translocase ABCB1target Albumincarrier alpha1-acid glycoproteincarrier
Propofol	A medication used in general anesthesia and for sedation.	Cytochrome P450 2B6enzyme UDP-glucuronosyltransferase 1A1enzyme UDP-glucuronosyltransferase 1A9enzyme Gamma-aminobutyric acid receptor subunit beta-2target Gamma-aminobutyric acid receptor subunit beta-3target Albumincarrier Sodium channel protein type 4 subunit alphatarget Sodium channel protein type 2 subunit alphatarget Fatty-acid amide hydrolase 1enzyme Cytochrome P450 2C9enzyme UDP-glucuronosyltransferase 1A8enzyme Cytochrome P450 2E1enzyme Cytochrome P450 1B1enzyme Cytochrome P450 1A1enzyme Cytochrome P450 1A2enzyme Cytochrome P450 2C18enzyme Cytochrome P450 2C19enzyme Cytochrome P450 2C8enzyme UDP-glucuronosyltransferase 1-6enzyme GABA(A) Receptortarget ATP-dependent translocase ABCB1transporter

Clinical Trials

Not Available