disease caused by Salmonella typhi (DBCOND0093740)

Identifiers

Synonyms
Salmonella Typhi Infection / Enteric Fever / Typhoid Fever / Typhoid / Typhoid fever, unspecified / Typhoid fever (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Ampicillin
A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
Cefixime
A third generation cephalosporin used to treat susceptible Gram-negative and Gram-positive bacterial infections.
Ceftriaxone
A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.
Chloramphenicol succinate
A broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains.
Hepatitis A Vaccine
An inactivated vaccine against infection with the Hepatitis A virus.
Typhoid Vaccine Live
Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain Salmonella typhi Ty21a. The vaccine prevents the development of typhoid fever,...
No drug targets
Typhoid vaccine
A vaccine used to prevent typhoid.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03067961
Investigating Typhoid Fever PathogenesisNo drug interventionsbasic_scienceNot Availableunknown_status
NCT03554213
Typhoid Conjugate Vaccine Introduction in Navi Mumbai, IndiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03889067
Understanding How Salmonella Typhi Infects Humans (Bottlenecks)No drug interventionsbasic_scienceNot Availablecompleted
NCT01421693
Gatifloxacin Versus Ceftriaxone in the Treatment of Enteric Fevertreatment4completed
NCT01766830
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)No drug interventionsdiagnosticNot Availablecompleted
NCT01405521
Understanding Typhoid Disease After Vaccinationprevention2completed
NCT02324751
Vaccines Against Salmonella Typhiprevention2completed
NCT04349553
Study to Evaluate the Safety, Tolerability and Immunogenicity of a Potential Enteric Fever VaccineNo drug interventionsprevention1completed
NCT04878549
Transcriptomic Responses for the Identification of PathogensNo drug interventionsNot AvailableNot Availableunknown_status
NCT00498654
Dose Ranging Study to Determine the Safety, Reactogenicity and Immunogenicity of Typhoid Fever Vaccine (Ty800) in Healthy Adult Subjectsprevention2completed
NCT05613205
Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adultsprevention1recruiting
NCT04235361
Mobile Point of Care Diagnostic Testing for Ebola Virus Disease in DRCNo drug interventionsNot AvailableNot Availableunknown_status
NCT00342628
Safety, Immunogenicity and Compatibility With DTP of a Typhoid Fever Vaccine in InfantsNo drug interventionsprevention2completed
NCT04830371
Non-inferiority and Safety Study of EuTCV Compared to Typbar-TCV in Healthy 6 Months-45 Years Aged ParticipantsNo drug interventionsprevention2 / 3completed
NCT01193907
Safety and Immunogenicity of Three Formulations of Vi-CRM197 Vaccine Against S. Typhi in Adults (18-40 Years Old)prevention2completed
NCT02391909
Phase 4 Study To Assess The Safety Of Vivotif At Different Release Titers Among TravelersNot AvailableNot Availablecompleted
NCT03956524
Safety and Tolerability of Typhoid Conjugate Vaccine (EuTCV) in Healthy Adultstreatment1completed
NCT01438996
Extension Study of H01_04TP to Evaluate the Booster Response Induced by Vi-CRM197 in Adultsprevention2completed
NCT04154722
Comparison of Two Drugs Regimen in Treatment of Complicated Typhoid Fever in Childrentreatment4completed
NCT05119426
Effectiveness of a Typhoid Conjugate Vaccine in DRCNo drug interventionsprevention4recruiting
NCT06546982
Diagnosis and Staging of Typhoid Fever Using Surface-enhanced Raman Spectroscopy Liquid BiopsyNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT00386789
Long Term Protection by and Persistence of Vi Antibodies Induced by Vi-rEPA Conjugate Vaccines in Vietnamese Children Injected at 2-5 Years or at 5-8 Years of AgeNo drug interventionsNot AvailableNot Availablecompleted
NCT01437267
Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Children, Older Infants and Infantsprevention2completed
NCT03926455
Safety and Immunogenicity of Typhax, a Typhoid Vaccineprevention1completed
NCT05579821
Evaluation Study of DPP® Typhoid AssayNo drug interventionsNot AvailableNot Availablecompleted
NCT05562102
TyVECO: Surveillance ProtocolNo drug interventionsNot AvailableNot Availableunknown_status
NCT04801602
Commercial Typhoid Tests Validation TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT04673487
Commercial Typhoid Tests ValidationNo drug interventionsNot AvailableNot Availableunknown_status
NCT04543877
WHNRC (Western Human Nutrition Research Center) Fiber Intervention Studybasic_science0recruiting
NCT00277147
Salmonella Typhi Vi O-Acetyl Pectin-rEPA Conjugate VaccineNo drug interventionstreatment1completed
NCT06104345
Immune Response Elicited by Concomitant Administration of Oral Typhoid Fever (Vivotif®) and Cholera (Dukoral®) Vaccinesprevention4recruiting
NCT04852185
Evaluation of Typhoid Conjugate Vaccine Effectiveness in GhanaNo drug interventionsprevention4recruiting
NCT01608815
Study of a Single Dose of SP093 Typhoid Vi Polysaccharide Vaccine in Japanese Subjectsprevention3completed
NCT01123941
Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Adult (18-40 Years Old)prevention1completed
NCT04349826
The Azithromycin and Cefixime Treatment of Typhoid in South Asia Trial (ACT-South Asia Trial)treatment4recruiting
NCT05500482
Vellore Typhoid Vaccine Impact TrialNo drug interventionsprevention4recruiting
NCT01229176
Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Adults, Children, Older Infants and Infantsprevention2completed
NCT02224040
Typhoid Fever: Combined vs. Single Antibiotic Therapytreatment4unknown_status
NCT02947295
Global Genomic and Proteomic Profiling of African Children With Typhoid FeverNo drug interventionsNot AvailableNot Availablecompleted
NCT04083950
Induction of Gut Permeability by an Oral Vaccinebasic_science0active_not_recruiting
NCT02192008
Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge StudyNo drug interventionsbasic_scienceNot Availablecompleted
NCT00326443
CVD 909 Vi Prime Boost StudyNo drug interventionsprevention1completed
NCT05771779
Co-administration Study of OCV, TCV and MRprevention3not_yet_recruiting
NCT01466387
A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adultsprevention3completed
NCT00131833
Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, ChinaNo drug interventionsprevention4completed
NCT03933098
Immune Non-inferiority and Safety of a Vi-DT Typhoid Conjugate VaccineNo drug interventionsprevention3unknown_status
NCT01019083
Studies of Immune Responses to Orally Administered Vaccines in Developing Countrybasic_science1 / 2completed
NCT02645032
Safety and Immunogenicity of a Vi-DT Typhoid Conjugate Vaccineprevention1completed
NCT03312699
Effects of Aging on Primary and Secondary Vaccine Responses in a 15-Year Longitudinal Cohortbasic_science1completed
NCT04204096
Immune Equivalence Between Multi-dose and Single Dose Formulation of Vi-DT and Their Overall Safety (Phase III)prevention3completed
NCT03299426
Clinical Efficacy of Typhoid Conjugate Vaccine (Vi-TCV) Among Children Age 9 Months Through 12 Years in Blantyre, MalawiNo drug interventionsprevention3active_not_recruiting
NCT05475379
Non-inferiority Trial of Locally Manufactured Typhoid Conjugate Vaccine 'Typhocon' in Bangladeshprevention1 / 2unknown_status
NCT03614533
Typhoid Conjugate Vaccine Trial Among Children Younger Than 2 Years in Ouagadougou, Burkina FasoNo drug interventionsprevention2completed
NCT00125047
Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhoodprevention4completed
NCT00131820
Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central VietnamNo drug interventionsprevention4completed
NCT00679172
Immunogenicity, Safety and Tolerability of the Typhoid Fever Vaccine Candidate M01ZH09 in Healthy AdultsNo drug interventionsprevention2completed
NCT03527355
Safety, Reactogenicity and Immunogenicity of Vi-DT;Typhoid Conjugate Vaccineprevention2completed
NCT00125008
Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Feverprevention4completed