Oropharyngeal Candidiasis

DrugDrug NameDrug Description
DB00362AnidulafunginAn antifungal used in the treatment of several types of candida infections.
DB00520CaspofunginAn echinocandin used to treat a variety of fungal infections.
DB00257ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DB00196FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
DB01167ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
DB01110MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
DB01263PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
DrugDrug NameTargetType
DB00362Anidulafungin1,3-beta-glucan synthase component FKS1target
DB00520CaspofunginSolute carrier family 22 member 1transporter
DB00520CaspofunginP-glycoprotein 1transporter
DB00520CaspofunginSolute carrier family 22 member 6transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B1transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B3transporter
DB00520CaspofunginCytochrome P450 3A4enzyme
DB00520Caspofungin1,3-beta-glucan synthase component FKS1target
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleP-glycoprotein 1transporter
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleCytochrome P450 51target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleHydroxycarboxylic acid receptor 2target
DB00257ClotrimazoleBile salt export pumptransporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
DB00257ClotrimazoleErgosteroltarget
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleP-glycoprotein 1transporter
DB00196FluconazoleCytochrome P450 51target
DB00196FluconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleP-glycoprotein 1transporter
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01110MiconazoleCytochrome P450 2C9enzyme
DB01110MiconazoleCytochrome P450 2D6enzyme
DB01110MiconazoleCytochrome P450 3A4enzyme
DB01110MiconazoleP-glycoprotein 1transporter
DB01110MiconazoleCytochrome P450 51target
DB01110MiconazoleNitric oxide synthase, endothelialtarget
DB01110MiconazoleNitric oxide synthase, inducibletarget
DB01110MiconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01110MiconazoleCytochrome P450 2A6enzyme
DB01110MiconazoleCytochrome P450 2B6enzyme
DB01110MiconazoleCytochrome P450 2C19enzyme
DB01110MiconazoleCytochrome P450 2E1enzyme
DB01110MiconazoleNuclear receptor subfamily 1 group I member 2target
DB01110MiconazoleLanosterol 14-alpha demethylaseenzyme
DB01110MiconazoleCytochrome P450 19A1enzyme
DB01110MiconazoleCalcium-activated potassium channeltarget
DB01110MiconazoleVoltage-gated Potassium Channelstarget
DB01110MiconazoleInward rectifier potassium channeltarget
DB01110MiconazoleVoltage gated L-type calcium channeltarget
DB01110MiconazoleSerum albumincarrier
DB01110MiconazoleCytochrome P450 2C8enzyme
DB01263PosaconazoleCytochrome P450 3A4enzyme
DB01263PosaconazoleP-glycoprotein 1transporter
DB01263PosaconazoleCytochrome P450 51target
DrugDrug NamePhaseStatusCount
DB01141Micafungin1Completed2
DB00196Fluconazole4Completed1