Cholera (Disorder) (DBCOND0134687)

Identifiers

Synonyms
Cholera / Cholera (disorder) / Vibrio cholera infection / Cholera due to Vibrio cholerae 01, biovar cholerae / Cholera, unspecified / Vibrio cholerae gastroenteritis / Vibrio cholera gastroenteritis / Unspecified cholera / Cholera due to Vibrio cholerae

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Demeclocycline
A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
Minocycline
A tetracycline analog used to treat a wide variety of infections in the body.
Tetracycline
An antibiotic used to treat a wide variety of susceptible infections.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03220737
VAXCHORA Pediatric Study to Assess Safety and Immunogenicityprevention4completed
NCT04853186
Impact Study of Cholera Vaccination in Endemic Areas - Clinical SurveillanceNo drug interventionsNot AvailableNot Availablerecruiting
NCT05829772
Impact Study of Cholera Vaccination in Endemic Areas - SeroprevalenceNo drug interventionsNot AvailableNot Availablecompleted
NCT06193408
Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in CholeraNo drug interventionstreatment2completed
NCT05771779
Co-administration Study of OCV, TCV and MRprevention3not_yet_recruiting
NCT00419133
Immunogenicity of One Versus Two Doses of Killed Oral Cholera Vaccineprevention2completed
NCT02864433
Evaluation of a Pilot Program to Introduce Cholera Vaccine in Haiti as Part of Global Cholera Control EffortsNo drug interventionsNot AvailableNot Availablecompleted
NCT02145377
PXVX0200 (CVD103-HgR) vs Shanchol in MaliNo drug interventionsprevention2completed
NCT01339845
Introduction of Cholera Vaccine in BangladeshNo drug interventionshealth_services_researchNot Availablecompleted
NCT01019083
Studies of Immune Responses to Orally Administered Vaccines in Developing Countrybasic_science1 / 2completed
NCT01811771
Oral Cholera Vaccine Delivery in Rural BangladeshNo drug interventionspreventionNot Availablecompleted
NCT04326478
Single Dose Azithromycin to Prevent Cholera in Childrenprevention2recruiting
NCT02027207
Single Dose Oral Cholera Vaccine Study in Dhaka, BangladeshNo drug interventionsprevention3completed
NCT00741637
Safety and Immunogenicity of Single Dose Choleragarde® in HIV-Seropositive AdultsNo drug interventionsprevention2completed
NCT04816552
Water, Sanitation, and Hygiene Mobile Health Messages as an Innovative Tool to Facilitate Behavior ChangeNo drug interventionspreventionNot Availablecompleted
NCT06455852
Correlates of Protection for Cholerabasic_scienceNot Availablenot_yet_recruiting
NCT00624975
Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi InfantsNo drug interventionsprevention2terminated
NCT01949675
A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in the Philippinesprevention4completed
NCT05814042
Next Generation ORS: Controlled Trial Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrheatreatment2 / 3recruiting
NCT00349999
Protective Immunity to Human Cholera in BangladeshNo drug interventionsNot AvailableNot Availablecompleted
NCT04760236
Immune Non-Inferiority, Safety and Lot-to-Lot Consistency of Oral Cholera Vaccine-Simplified Compared to Shanchol™prevention3completed
NCT02928341
Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of CongoNo drug interventionspreventionNot Availablecompleted
NCT00401934
Immunity to Human Cholera in BangladeshNo drug interventionsNot AvailableNot Availablecompleted
NCT00289224
Randomized Controlled Trial of Killed Oral Cholera Vaccine in Kolkataprevention3completed
NCT06003816
Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)No drug interventionspreventionNot Availablerecruiting
NCT02742558
Safety and Immunogenicity of Locally Manufactured Oral Cholera VaccineNo drug interventionsprevention2completed
NCT01823939
PK Study of iOWH032 in Adult Male/Female Healthy Volunteers & Adult Males With CholeraNo drug interventionstreatment1completed
NCT05657782
First in Human Phase 1 Ascending Dose Study of PanChol in Healthy VolunteersNo drug interventionsprevention1recruiting
NCT02502331
Safety and Immunogenicity of a New Formulation of Euvichol®prevention3unknown_status
NCT05507229
A Phase III Randomized, Modified Double-blind, Multi-centric, Comparative Study, to Evaluate the Non-inferiority of Immunogenicity and Safety of Hillchol® (BBV131)to Shanchol™ Along With Lot-to-lot Consistency of Hillchol®(BBV131).No drug interventionsprevention3unknown_status
NCT00229944
Single Dose Azithromycin in the Treatment of Adult Choleratreatment3completed
NCT01524640
Bridging Study for Killed Oral Cholera Vaccine in Ethiopiaprevention4completed
NCT00142272
Single Dose Ciprofloxacin in the Treatment of Childhood Cholera:Randomized Controlled Clinical Trialtreatment3completed
NCT02499172
Follow-up of Pregnant Women After a Mass Vaccination of Oral Cholera Vaccine (ShancholTM) in Nsanje MalawiNo drug interventionspreventionNot Availableterminated
NCT03373669
Effect of Extended Dose Intervals on the Immune Response to Oral Cholera Vaccineprevention4completed
NCT00709410
Mass Oral Cholera Vaccination in ZanzibarpreventionNot Availablecompleted
NCT03251495
Immunologic Responses to a Live Attenuated Oral Cholera Vaccineprevention2recruiting
NCT05166850
Preventative Intervention for Cholera for 7 DaysNo drug interventionspreventionNot Availablerecruiting
NCT00672308
Efficacy of Benefiber-Added, Reduced-Osmolarity WHO-ORS in the Treatment of Cholera in AdultsNo drug interventionstreatment2completed
NCT00548054
Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infantsprevention2unknown_status
NCT05453253
Immune Response to a Delayed Second Dose of Oral Cholera Vaccineprevention4active_not_recruiting
NCT06104345
Immune Response Elicited by Concomitant Administration of Oral Typhoid Fever (Vivotif®) and Cholera (Dukoral®) Vaccinesprevention4recruiting
NCT00119197
Safety and Immunogenicity of Oral Cholera Vaccine in Kolkataprevention2completed
NCT00128011
Safety and Immunogenicity of a New Formulation of a Bivalent Killed, Whole-Cell Oral Cholera Vaccineprevention2completed
NCT01508507
Effectiveness of a Bivalent Killed Whole Cell Based Oral Cholera VaccineNo drug interventionsNot AvailableNot Availableunknown_status
NCT00741052
Ciprofloxacin Multiple Dose for Adult Choleratreatment3completed
NCT01365442
Pilot Introduction of Oral Cholera Vaccine in Orissa, IndiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02823899
Safety and Immunogenicity of Locally Manufactured New (HL-OCV) Oral Cholera VaccineNo drug interventionsprevention1 / 2completed
NCT03998449
Immunogenicity of Cholera Vaccine in Children With IBDNo drug interventionspreventionNot Availablecompleted
NCT06498817
Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)No drug interventionspreventionNot Availablerecruiting
NCT04008134
Cholera-Hospital-Based-Intervention-for-7-daysNo drug interventionspreventionNot Availablecompleted
NCT00226616
Zinc Supplementation in Cholera Patientstreatment3completed
NCT02094586
A Phase 3 Lot to Lot Consistency Study of Live Oral Cholera Vaccine, PXVX0200 in Healthy AdultsNo drug interventionsprevention3completed
NCT02434822
A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in Dominican Republicprevention3completed
NCT01579448
Evaluation of a Boosting Regimen With Oral Cholera Vaccineprevention4completed
NCT05732766
To Evaluate Safety of Oral Cholera Vaccine Hillchol® (BBV131)No drug interventionsprevention3recruiting
NCT02100631
A Study of Live Oral Cholera Vaccine, PXVX200 in Healthy Older AdultsNo drug interventionsprevention3completed
NCT01233362
Study of Alternative Vaccination Schedule of Oral Cholera Vaccineprevention2completed
NCT00464867
Effect of Probiotic on Immunogenicity of Oral Cholera VaccinepreventionNot Availablecompleted
NCT01585181
Safety and Immunogenicity of the Live Oral Cholera Vaccine Candidate PXVX0200No drug interventionsprevention1completed
NCT02727855
Cholera Vaccine Investment Strategy in BangladeshNo drug interventionsNot AvailableNot Availablecompleted
NCT01895855
Safety and Efficacy Challenge Study of Live Oral Cholera Vaccine Candidate,PXVX0200, to Prevent CholeraNo drug interventionsprevention3completed
NCT04150250
Cholera Anti-Secretory Treatment TrialNo drug interventionstreatment2completed