Bowel Preparation for Colonoscopy (DBCOND0039387)

Identifiers

Synonyms

Preparation for Colonoscopy / Colon Cleansing in Preparation for Colonoscopy / Cleansing of the colon as a preparation for colonoscopy therapy / Colon Cleansing for Colonoscopy / Colon Prep for Colonoscopy / Cleansing of the colon as a preparation for colonoscopy / Bowel Cleansing Prior to Colonoscopy / Bowel Cleansing in Preparation for Colonoscopy / Bowel Cleansing for Colonoscopy

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Citric acid	An anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products.	Beta-lactamase 2target Aldo-keto reductase family 1 member B1target Citrate synthase, mitochondrialtarget Proto-oncogene tyrosine-protein kinase Srctarget Ribonuclease pancreatictarget Isocitrate dehydrogenase [NADP]target Eosinophil cationic proteintarget Beta-lactamasetarget Fumarate hydratase class IItarget 6-phosphogluconolactonasetarget L-amino-acid oxidasetarget Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1target Cytochrome c peroxidasetarget Hepatocyte growth factor-regulated tyrosine kinase substratetarget Invasintarget Intron-associated endonuclease 1target Short tail fiber protein gp12target Malate dehydrogenase, mitochondrialtarget N5-carboxyaminoimidazole ribonucleotide mutasetarget 50S ribosomal protein L4target Carboxypeptidase Btarget Hexon proteintarget Riboflavin biosynthesis proteintarget Beta-fructosidasetarget Putative stringent starvation protein Atarget Citrate synthasetarget RNA 3'-terminal phosphate cyclasetarget U6 snRNA-associated Sm-like protein LSm6target Pleckstrin homology domain-containing family A member 1target Fe(3+)-binding periplasmic proteintarget Signal recognition particle receptor FtsYtarget Nicotinate-nucleotide adenylyltransferasetarget N utilization substance protein B homologtarget Complement component C8 gamma chaintarget Ribonucleoside-diphosphate reductase subunit betatarget Glutamine synthetase 1target 2-methylcitrate synthasetarget Prostaglandin F synthasetarget Adenine phosphoribosyltransferasetarget Glucose-1-phosphate thymidylyltransferasetarget Glyoxalase family proteintarget Laccase domain protein YfiHtarget Ribose-5-phosphate isomerase Atarget GMP synthase [glutamine-hydrolyzing]target Inosine triphosphate pyrophosphatasetarget Lysozymetarget Glycerol uptake operon antiterminator regulatory proteintarget 3-carboxy-cis,cis-muconate cycloisomerasetarget Pyruvate decarboxylasetarget Solute carrier organic anion transporter family member 2B1transporter Metallo-beta-lactamase type 2target Transient receptor potential cation channel subfamily V member 4target Lanosterol 14-alpha demethylasetarget
Magnesium oxide	A compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health.	No drug targets
Picosulfuric acid	A stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults.	Arylsulfate sulfotransferase AssTenzyme
Polyethylene glycol	A laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.	ATP-dependent translocase ABCB1transporter

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03332485	Safety and Efficacy Study of an Edible Colonoscopy Preparation	Ascorbic acid Polyethylene glycol Potassium chloride Sodium ascorbate Sodium chloride Sodium sulfate	other	2	completed
NCT00318305	Patient Preference With Visicol Tablet Preparation for Colonoscopy	No drug interventions	Not Available	Not Available	completed
NCT05107505	Evaluation of The Factors Affecting Bowel Preparation Adequacy for Colonoscopy	No drug interventions	Not Available	Not Available	unknown_status
NCT01063049	Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation	Bisacodyl Polyethylene glycol Potassium chloride Sodium bicarbonate Sodium chloride	treatment	4	completed
NCT02661750	Safety and Efficacy of High Dose Bowel Preparation Solutions for Patients With Difficult To Clean Colons For Colonoscopy	No drug interventions	Not Available	Not Available	completed
NCT01603654	Sodium Picosulphate/Magnesium Citrate and Low-volume PEG -Ascorbic Acid as Preparation for Colonoscopy	Alginic acid Ascorbic acid Citric acid Magnesium citrate Magnesium oxide Picosulfuric acid Polyethylene glycol Potassium chloride Sodium ascorbate Sodium chloride Sodium sulfate	treatment	4	completed
NCT02215954	A Phase III Study With FE 999169 Versus Niflec for Colon Cleansing	No drug interventions	treatment	3	completed
NCT01929590	Low-volume Polyethylene Glycol Bowel Preparation for Colonoscopy	Polyethylene glycol Potassium chloride Sodium bicarbonate Sodium chloride	diagnostic	3	completed
NCT01415687	Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose	Bisacodyl Citric acid Magnesium citrate Magnesium oxide Picosulfuric acid Polyethylene glycol Potassium chloride Sodium bicarbonate Sodium chloride Sodium sulfate	Not Available	3	completed
NCT00611442	Split Dose Golytely With Amitiza Pretreatment Versus Split Dose Golytely Plus Placebo in Outpatient Colonoscopy	Lubiprostone	treatment	Not Available	completed
NCT02376465	A Pilot Evaluation of an Experimental BLI4600 Formulation for Bowel Preparation in Adult Patients Undergoing Colonoscopy	No drug interventions	prevention	2	completed
NCT01765491	Comparison of Two Methods of Bowel Preparation for Colonoscopy in Hospitalized Patients	No drug interventions	diagnostic	Not Available	completed
NCT01719653	A Comparison of 5 Low Volume Bowel Preparations	Ascorbic acid Polyethylene glycol Potassium chloride Sodium ascorbate Sodium bicarbonate Sodium chloride Sodium sulfate	treatment	4	completed
NCT01853709	Multidisciplinary Approach Versus Conventional Approach in Colonic Preparation of Hospitalized Patients	Bisacodyl	treatment	4	unknown_status
NCT02839824	Evaluation of the Quality of Bowel Cleansing in a Real Clinical Practice Setting	No drug interventions	Not Available	Not Available	completed
NCT05291325	Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy	Linaclotide	diagnostic	Not Available	completed
NCT01028573	A Study Comparing PEG-3350 (Miralax) and Gatorade With PEG-ELS (Golytely) for Bowel Preparation Prior to Colonoscopy	Polyethylene glycol Potassium chloride Sodium bicarbonate Sodium chloride Sodium sulfate	diagnostic	Not Available	unknown_status
NCT06514989	Efficacy of Low-residue Full Nutritive Formula Powder in Bowel Preparation for Colonoscopy	No drug interventions	diagnostic	Not Available	recruiting
NCT05465889	Efficacy and Safety of Oral Sulfate Solution on Bowel Preparation for Colonoscopy	Sulfate ion	diagnostic	3	completed
NCT03055689	Bowel Preparation for Repeat Colonoscopy After Preparation Failure (RepeatPrep Study)	No drug interventions	supportive_care	Not Available	completed
NCT00771485	Study of Efficacy of Bowel Preparation Before Colonoscopy	Levoglucose Salicylic acid	diagnostic	2	completed
NCT00621920	Efficacy Study of Bowel Preparation Before Colonoscopy	No drug interventions	treatment	2	completed
NCT01788709	PEG-Electrolyte Solution (FORTRANS®) With Mentholyptus Drops (Halls®) Versus Reduced Volume Ascorbic Acid Supplemented PEG-Electrolyte (MoviPrep®) in Colonoscopy Preparation	No drug interventions	screening	4	completed
NCT01624454	Optimal Bowel Cleansing Trial	No drug interventions	diagnostic	Not Available	completed