Dependence, Cocaine (DBCOND0045954)

Identifiers

Synonyms

Addiction, Cocaine / Cocaine Dependence / Cocaine Addiction / Cocaine Addictions / Cocaine dependence, unspecified use / Cocaine dependence (disorder) / Dependence on cocaine / Drug Dependence / Unspecified drug dependence / Drug dependence, unspecified / Addiction to drugs / Dependent drug abuse (disorder) / Drug addiction / Dependence drug (NOS) / Drug dependence NOS / Psychoactive substance dependence (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03345394	Effectiveness of Contingency Management in the Treatment of Crack Addiction in Brazil	No drug interventions	treatment	Not Available	completed
NCT01025219	A Contribution to the Analysis of the Phenotypic Heterogeneity in Crack/Cocaine Addiction : a Case Control Study	No drug interventions	diagnostic	Not Available	unknown_status
NCT04907357	rTMS for Stimulant Use Disorders	No drug interventions	treatment	Not Available	completed
NCT05974202	rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder	No drug interventions	treatment	2	not_yet_recruiting
NCT00421603	A Placebo-Controlled Study of Mixed Amphetamine Salts and Topiramate for the Treatment of Cocaine Dependence	Amphetamine Topiramate	treatment	2	completed
NCT06189690	Effect of HF rTMS on Serum BDNF in Cocaine Use Disorder	No drug interventions	treatment	Not Available	recruiting
NCT01137890	Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse	Cocaine Zonisamide	other	1 / 2	completed
NCT01153464	Effectiveness of Extended Treatment for Drug Dependence (ETDD) in the City Study	No drug interventions	treatment	2	completed
NCT02003664	A Study of Baclofen ER	Baclofen	treatment	2	withdrawn
NCT01651364	A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence	Cabergoline	Not Available	1	completed
NCT05824221	Effect of rTMS on Neurotrophines Levels in CUD	No drug interventions	basic_science	Not Available	not_yet_recruiting
NCT01281202	Vigabatrin for the Treatment of Cocaine Dependency	Vigabatrin	treatment	2 / 3	completed
NCT02134002	A PET Exploration of the Mechanism of Action of Dopamine Beta-hydroxylase Inhibition in Cocaine Addicts	Disulfiram	treatment	4	withdrawn
NCT00218387	Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1	Modafinil	treatment	2	completed
NCT01680887	A Phase II Trial of Varenicline for the Treatment of Cocaine Dependence	Varenicline	treatment	2	completed
NCT02774954	Change the Cycle: An RCT to Prevent Injection Initiation	No drug interventions	prevention	Not Available	completed
NCT06125054	Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction	Ketamine	treatment	2	recruiting
NCT00654953	Clinical Efficacy of Sertraline Augmented With Gabapentin in Depressed, Recently Abstinent Cocaine-dependent Humans	Gabapentin Sertraline	treatment	2	completed
NCT01153477	Effectiveness of Enhanced Treatments for Drug Dependence	No drug interventions	treatment	2	completed
NCT01062945	The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine	Doxazosin	Not Available	1	completed
NCT02111798	Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence	Bupropion	treatment	2 / 3	completed
NCT00688805	Effects of Propranolol on Responses to Drug-Related Imagery Scripts	Propranolol	basic_science	1	terminated
NCT00577005	Efficacy of Levetiracetam in Cocaine-Abusing Methadone Maintained Patients	Levetiracetam	treatment	2	completed
NCT00880997	The Efficacy of Doxazosin for Cocaine Users	Doxazosin	treatment	1	completed
NCT00123383	Randomised Placebo-Controlled Trial of Modafinil for Cocaine Dependence	Modafinil	treatment	2	unknown_status
NCT00495183	Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence	Biperiden Caffeine	treatment	4	unknown_status
NCT03833583	tDCS to Reduce Craving in Cocaine Addiction	No drug interventions	device_feasibility	Not Available	unknown_status
NCT00713583	Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence	Carbidopa Levodopa	treatment	2	completed
NCT00685178	Clinical Trial of Topiramate for Cocaine Addiction	Topiramate	treatment	2	completed
NCT01652378	Pharmacologic MRI in Cocaine Addiction	Lidocaine Ondansetron	Not Available	Not Available	completed
NCT00322309	Efficacy of Mirtazapine in Depressed Cocaine Dependent Subjects	Mirtazapine	treatment	2	completed
NCT00737256	A Double-Blind, Controlled Study of Aripiprazole in Co-Morbid Schizophrenia and Cocaine Dependence	Aripiprazole Perphenazine	treatment	2	unknown_status
NCT03527485	Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PET	No drug interventions	diagnostic	Not Available	completed
NCT01802515	A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance Treatment	Atomoxetine	treatment	Not Available	terminated
NCT02080832	Brain Function and Structure in Cocaine Dependence	Citalopram	treatment	2	completed
NCT00701532	Brain Imaging Study of the Effects of Modafinil in Cocaine Addiction	Modafinil	treatment	3	completed
NCT01038232	Measuring Distress Tolerance With Functional MRI	No drug interventions	Not Available	Not Available	completed
NCT05857852	Low-Intensity Focused Ultrasound for Cocaine Use Disorder	No drug interventions	health_services_research	Not Available	recruiting
NCT00685659	Effectiveness of Extended Treatments for Drug Dependence	No drug interventions	treatment	Not Available	completed
NCT01986075	A Sequenced Behavioral and Medication Intervention for Cocaine Dependence	Amphetamine	treatment	1 / 2	completed
NCT02994875	Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine Dependence	No drug interventions	treatment	0	completed
NCT03349606	Cocaine Use Disorder and Cortical Dopamine	Dextroamphetamine	basic_science	0	completed
NCT05562349	Clavulanic Acid for the Treatment of Cocaine Use Disorder	Clavulanic acid Microcrystalline cellulose	treatment	2	active_not_recruiting
NCT00439049	Substance Abuse Pre-Treatment Screening Study	Carbidopa Dextroamphetamine Levodopa Modafinil Naltrexone	Not Available	Not Available	recruiting
NCT02927236	Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use	No drug interventions	basic_science	4	completed
NCT00223236	Trial of Citicoline Therapy in Patients With Mania or Hypomania and Cocaine Abuse/Dependence	Citicoline	treatment	3	completed
NCT00808119	Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336 in Healthy, Male Subjects	No drug interventions	basic_science	1	completed
NCT02124941	Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS	Cysteine	diagnostic	1	completed
NCT00842517	Long Term Maintenance of Drug Abstinence	No drug interventions	treatment	1	completed
NCT01490216	Pilot Study of Lisdexamfetamine for Treatment of Cocaine Dependence	Lisdexamfetamine	basic_science	1	terminated
NCT01036516	PET Assays of Striatal Dopamine Marker in Cocaine Craving	No drug interventions	Not Available	Not Available	completed
NCT00376558	Imaging the Neurobiology of a Behavioral Treatment for Cocaine Dependence	No drug interventions	treatment	Not Available	completed
NCT00249535	Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2	No drug interventions	treatment	Not Available	completed
NCT01914835	Neuropsychological Rehabilitation on Cocaine/Crack Dependents	No drug interventions	treatment	Not Available	unknown_status
NCT01031563	Risk Perception in Drug-Dependent Adults With and Without Schizophrenia	No drug interventions	Not Available	Not Available	completed
NCT00965263	Therapeutic Cocaine Vaccine: Human Laboratory Study	Cocaine	treatment	2	completed
NCT01327586	Abstinence-Linked Money Management Multisite	No drug interventions	treatment	2	completed
NCT01406522	Tacrine Effects on Cocaine Self-Administration and Pharmacokinetics	Tacrine	treatment	2	withdrawn
NCT02596022	The Effect of Glutamatergic Modulation on Cocaine Self-administration	No drug interventions	treatment	2	completed
NCT00593125	Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients.	Levetiracetam	treatment	2	completed
NCT00756925	Gender and Neural Substrates of Stress and Craving	Corticorelin ovine triflutate	Not Available	Not Available	completed
NCT00451230	Metabolic Effects of Cocaine	Cocaine Hydrocortisone	Not Available	Not Available	completed
NCT01601730	Modafinil - Escitalopram Study for Cocaine Dependence	Escitalopram Modafinil	Not Available	1	completed
NCT01393457	Cognitive Remediation for Cocaine Dependence	Carbidopa Levodopa Ropinirole	treatment	2	completed
NCT02141620	n-Acetylcysteine and Cocaine	Acetylcysteine Cocaine	basic_science	0	completed
NCT00585520	Sex Differences in Progesterone Effects on Responses to Stress and Drug Cues	Progesterone	Not Available	1	completed
NCT01593982	Repetitive Transcranial Magnetic Stimulation in Symptoms of Attention Deficit Hyperactivity Disorder and Cognitive Function In Cocaine Addicts	No drug interventions	treatment	2	unknown_status
NCT00958282	Treatment of Cocaine Dependence With Lisdexamfetamine	Lisdexamfetamine	treatment	2	completed
NCT01558973	FMRI of Stress and Addictive Disorders	No drug interventions	Not Available	Not Available	completed
NCT01822327	Treating Cocaine Abuse: A Behavioral Approach	No drug interventions	treatment	2	unknown_status
NCT00240227	Prazosin for ETOH or Cocaine Craving	Prazosin	treatment	Not Available	terminated
NCT00783276	An fMRI Study of SYN115 in Cocaine Dependent Subjects	Tozadenant	basic_science	0	completed
NCT01741376	Progesterone and Atomoxetine for Cocaine Cessation	Progesterone	treatment	Not Available	withdrawn
NCT00218660	Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1	Naltrexone	treatment	3	completed
NCT00582491	Modafinil, Sleep, and Cognition in Cocaine Dependence	Modafinil	Not Available	Not Available	completed
NCT02181491	PET Imaging in Cocaine Self Administration	No drug interventions	other	Not Available	completed
NCT01283191	Behavioral Incentives to Increase Exercise in Cocaine Dependent Women	No drug interventions	treatment	Not Available	completed
NCT00830362	Beta-blockade Effects on Memory for Cocaine Craving	Propranolol	treatment	2	completed
NCT01030692	Rivastigmine and Huperzine A as Treatments for Cocaine Dependence	Huperzine A Rivastigmine	Not Available	1	completed
NCT01267292	Psychopharmacology for Cocaine Dependence - Buspirone	Buspirone Methylphenidate Starch, corn	basic_science	2	completed
NCT02538744	Complementary Combination Therapy for Cocaine Dependence	Cocaine Doxazosin Modafinil	treatment	1	completed
NCT02559167	Cannabidiol and Cocaine Craving/Dependence	Cannabidiol	treatment	2	completed
NCT00385801	Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine Dependence	Risperidone	treatment	2	completed
NCT00689572	New Medication Treatment for Stimulant Dependence	Ondansetron	treatment	2	completed
NCT00385268	Pilot Trial of Acamprosate for the Treatment of Cocaine Dependence	Acamprosate	treatment	2	completed
NCT00566969	Cocaine Withdrawal and Pharmacotherapy Response	Carvedilol	health_services_research	Not Available	completed
NCT01906346	Impact of a Non-Drug Choice on Cocaine Reinforcement	Cocaine	basic_science	0	completed
NCT00227812	Integrated Treatment for Cocaine and Mood Disorders - 1	Bupropion	treatment	2	completed
NCT01468012	Imaging the Neurobiology of Behavioral and Medication Treatment for Cocaine Dependence	Carbidopa Entacapone Levodopa	treatment	2 / 3	completed
NCT00223210	An Add-On Trial of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence	Quetiapine	treatment	4	completed
NCT00838981	Pharmacotherapy & CM for Opioid and Cocaine Dependence	Methadone Modafinil	treatment	1 / 2	completed
NCT00373581	Effects of Vigabatrin on Cocaine Self-Administration	Cocaine Vigabatrin	treatment	2	terminated
NCT01846481	A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse	COCAINE ESTERASE (RBP-8000) Cocaine	treatment	2	completed
NCT00951314	Brain Glutamate Receptors and Cocaine Dependence	No drug interventions	Not Available	Not Available	terminated
NCT00227123	A Randomized Control Trial Comparing Quetiapine to Risperidone in Bipolar Disorder With Stimulant Dependence	Quetiapine Risperidone	treatment	Not Available	completed
NCT00567008	Chantix for Treating Cocaine Dependence	Varenicline	treatment	2	completed
NCT00697138	Agonist Replacement Therapy for Cocaine Dependence	Atomoxetine Dextroamphetamine	basic_science	1	completed
NCT00969943	Gender Differences in Response to Cues in Cocaine Dependence	No drug interventions	Not Available	Not Available	completed
NCT01790490	Glutamatergic Modulation of Cocaine-related Deficits	Ketamine Lorazepam	treatment	2	completed
NCT00368290	Modafinil Treatment for Cocaine Dependence and HIV High-Risk Behavior	Modafinil	treatment	2	completed
NCT01938664	A Pilot Study of Candesartan as a Treatment for Cocaine Dependence	Candesartan cilexetil	treatment	2	terminated
NCT04994821	tDCS to Reduce Craving in Cocaine Addiction- Phase 2 Study	No drug interventions	treatment	2	unknown_status
NCT00780702	Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients	No drug interventions	treatment	1	completed
NCT00913484	Disulfiram for Cocaine Abuse in Buprenorphine Treatment	Disulfiram	treatment	2	completed
NCT02455479	Safety Study of a Disrupted Adenovirus (Ad) Serotype Cocaine Vaccine for Cocaine-dependent Individuals	No drug interventions	treatment	1	recruiting
NCT06159387	Randomized, Double-blind, Placebo-controlled Cannabis Extract x Placebo for Cocaine Addicts	Medical Cannabis	treatment	4	recruiting
NCT00061087	Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1	Bupropion Methylphenidate	treatment	2 / 3	completed
NCT01715051	D-Serine for Cocaine Dependence Pilot	D-Serine	treatment	2	withdrawn
NCT03921151	5HT2CR Balance in Brain Connectivity in Cocaine Dependence	Mirtazapine	basic_science	1 / 2	completed
NCT00606853	Enhanced and Attendance-based Prize CM in Community Settings	No drug interventions	treatment	Not Available	completed
NCT01651377	Pramipexole as a Treatment for Cocaine Dependence	Pramipexole	Not Available	1	completed
NCT00167245	Topiramate for Alcohol and Cocaine Dependence	Topiramate	treatment	2	completed
NCT01134198	Investigation of Mifepristone (RU486) on Stress Sensitivity and Relapse Prevention in Cocaine Dependent Patients	Mifepristone	treatment	2 / 3	completed
NCT00297505	Serotonin, Impulsivity, and Cocaine Dependence Treatment	Citalopram	treatment	2	completed
NCT01171183	Carvedilol for Psychostimulant Dependence	Carvedilol	treatment	2	completed
NCT01145183	Pharmacogenetics of Doxazosin for Cocaine Dependence	Doxazosin	diagnostic	2	completed
NCT00527683	Double Blind Study of Vigabatrin for the Treatment of Cocaine Dependence	Vigabatrin	treatment	2	completed
NCT03554928	Longitudinal Assessment of Functional Connectivity in Treatment Engaged Cocaine Users	No drug interventions	Not Available	Not Available	completed
NCT01251393	Cocaine/Crack and Reduction of Compulsion With Biperiden	Biperiden	treatment	3	completed
NCT00733993	Caffeine and Cocaine	Amphetamine Caffeine	basic_science	1 / 2	completed
NCT00280293	Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine Dependency	Lamotrigine	treatment	4	completed
NCT00969878	Multisite Controlled Trial of Cocaine Vaccine	Aluminum hydroxide	treatment	2	completed
NCT01535937	The Effect of Brief Potent Glutamatergic Modulation on Cocaine Dependence	Ketamine Midazolam	treatment	1 / 2	terminated
NCT00167232	Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence	Naltrexone	treatment	3	completed
NCT01953432	Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse	Doxazosin	treatment	2	completed
NCT01641159	Study of Buspirone for Relapse-Prevention in Adults With Cocaine Dependence	Buspirone	treatment	2	completed
NCT03238859	10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine Dependence	No drug interventions	treatment	2	completed
NCT02152670	Understanding Dopamine Mechanisms in Cocaine Addiction Using AMPT and Methylphenidate With [11C]RAC/[11C]PHNO PET	Benzalkonium Dopamine Methylphenidate Tyrosine	other	Not Available	terminated
NCT00632099	Progesterone Treatment for Cocaine-dependent Women: A Pilot Study	Progesterone	treatment	2 / 3	completed
NCT01832649	Exercise as an Adjunctive Treatment for Cocaine Dependent Patients	No drug interventions	treatment	Not Available	completed
NCT01151813	Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol Craving	Varenicline	treatment	2	completed
NCT00553319	Study of Adderall-XR for the Treatment of Adult Attention Deficit Hyperactivity Disorder and Cocaine Dependence	Amphetamine	treatment	2 / 3	completed
NCT02080819	Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse	Carbidopa Levodopa	treatment	2	completed
NCT02098434	Ovarian Hormones and Stress Induced Drug Craving	No drug interventions	other	Not Available	completed
NCT01077024	Smoking-Cessation and Stimulant Treatment (S-CAST)	No drug interventions	treatment	3	completed
NCT00368524	Cost Effective Treatment for Dually Diagnosed Homeless	No drug interventions	treatment	Not Available	completed
NCT01137396	Modafinil, Sleep Architecture and Cocaine Relapse	Modafinil	treatment	2	completed
NCT01704196	A Multi-Center Trial of Nepicastat for Cocaine Dependence	Nepicastat	treatment	2	completed
NCT00167258	Effectiveness and Costs of Enhanced Cocaine Treatments	No drug interventions	treatment	2	completed
NCT00809835	Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine Abuse	Galantamine	treatment	2	completed
NCT02018263	Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in Humans	Cocaine Nicotine	basic_science	1	completed
NCT01431586	First in Humans Study of JDTic	No drug interventions	prevention	1	terminated
NCT03266939	Rebalancing the Serotonergic System in Cocaine Dependence	Lorcaserin	basic_science	1	unknown_status
NCT00448825	Novel Pharmacotherapy for Dual Dependence	Topiramate	treatment	3	unknown_status
NCT00149630	Pharmacogenetics of Disulfiram for Cocaine	Disulfiram Methadone	treatment	2	completed
NCT00611130	Vigabatrin for Treatment of Cocaine Dependence	Vigabatrin	treatment	2	completed
NCT00631748	Quetiapine for the Reduction of Cocaine Use	Quetiapine	treatment	Not Available	completed
NCT02255357	Investigation of Intranasal Oxytocin on Relapse Risk in Cocaine-dependent Patients.	Oxytocin	treatment	2 / 3	completed
NCT01143857	Human Behavioral Pharmacology Laboratory Study of Varenicline's Impact on Cocaine Reinforcement	Varenicline	treatment	2	withdrawn
NCT00249457	Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2	No drug interventions	treatment	Not Available	completed
NCT00656357	Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers	Cocaine Nepicastat	treatment	1 / 2	completed
NCT01397266	Study of the Effect of Magnetic Stimulation Repetitive Transcranial on Impulsivity in Cocaine Dependence	No drug interventions	treatment	2	unknown_status
NCT00344565	A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence	Modafinil	treatment	2	completed
NCT01036074	Reward Processing in Cocaine Addiction	No drug interventions	Not Available	Not Available	completed
NCT01249274	Progesterone for Postpartum Cocaine Relapse	Progesterone	treatment	Not Available	completed
NCT00567320	Efficacy of Varenicline in Methadone-Stabilized Cocaine Users	Varenicline	health_services_research	Not Available	completed
NCT03471182	Investigation of Cocaine Addiction Using mGluR5 PET and fMRI	Cocaine	other	1	completed
NCT01978431	Impulsivity and Stimulant Administration	Cocaine Methylphenidate	basic_science	1	completed
NCT00599573	Pharmacotherapy for HIV+ Stimulant Dependent Individuals	Ondansetron	treatment	Not Available	unknown_status
NCT01573273	Oxytocin in Cocaine Dependence	Oxytocin	other	Not Available	completed
NCT01535573	Citalopram for Cocaine Dependence	Citalopram	treatment	2	completed
NCT02302976	GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration	Cocaine Exenatide	other	1	completed
NCT03333460	Transcranial Magnetic Stimulation for Cocaine Addiction	No drug interventions	treatment	Not Available	unknown_status
NCT01176591	HBPL Study of the Impact of the NK1 Antagonist Aprepitant	Aprepitant	treatment	2	completed
NCT01963091	Effect of Oxytocin on Stress Response in Cocaine-dependent Individuals	Oxytocin	other	2	completed
NCT00218491	Effectiveness of N-Acetylcysteine (NAC) in Treating Cocaine Dependent Individuals - 1	Acetylcysteine	treatment	2	completed
NCT01377662	PHASE IIA: Trial of a Novel Ondansetron Formulation (OND-PR002) and Immediate-Release Methylphenidate (Ritalin®)(OND003IND)	Methylphenidate Ondansetron	treatment	2	completed
NCT00777062	VIVITROL as a Treatment for Cocaine and Alcohol Dependence	Naltrexone	treatment	2	completed
NCT03662529	Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting	No drug interventions	treatment	Not Available	completed
NCT01402492	Cocaine Use Reduction With Buprenorphine	Buprenorphine Naloxone Naltrexone	treatment	2 / 3	completed
NCT00249444	Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From Depression	Mirtazapine	treatment	2	completed
NCT01811940	Multicenter Trial of Combined Pharmacotherapy to Treat Cocaine Dependence	Amphetamine Dextroamphetamine Topiramate	treatment	2 / 3	completed
NCT01335867	Vigabatrin for Cocaine and Alcohol Dependence	Vigabatrin	treatment	2	terminated
NCT00744601	Impulsivity, Neural Deficits and Cocaine Addiction	No drug interventions	Not Available	Not Available	completed
NCT02935101	Effects of Glucocorticoids on Craving During Detoxification Treatment of Heroin and/or Stimulants	Prednisolone	basic_science	2	terminated
NCT00732901	Clinical Neurobiology of Serotonin and Addiction	Escitalopram	basic_science	2 / 3	completed
NCT02563769	Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study	Clavulanic acid Cocaine	treatment	1	completed
NCT00218569	Combined Treatment for Cocaine-Alcohol Dependence - 1	Naltrexone	treatment	2	completed
NCT00240110	Valproate Efficacy in Cocaine-Bipolar Comorbidity	Lithium carbonate Valproic acid	treatment	1 / 2	completed
NCT01778010	Modafinil for Smoked Cocaine Self-Administration	Cocaine Modafinil	treatment	2	completed
NCT01486810	Open-Label Pilot Study of Lisdexamfetamine for Cocaine Dependence	Lisdexamfetamine	treatment	1 / 2	completed
NCT00914381	Behavioral Treatment for Cocaine Dependent Women	No drug interventions	treatment	2	completed
NCT04411914	Pharmaco-Magnetic Resonance Spectroscopy (MRS) Study of Clavulanic Acid	Clavulanic acid	treatment	1	completed
NCT00567814	A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction	Metyrapone Oxazepam	treatment	Not Available	completed
NCT02416050	Predicting Relapse After Cocaine Inpatient Cessation	No drug interventions	Not Available	Not Available	completed
NCT00395850	Disulfiram for Cocaine Abuse	Disulfiram	treatment	2	completed
NCT00619723	Citicoline for Bipolar 1 Disorder and Cocaine Dependence	Citicoline	supportive_care	4	completed
NCT01601743	Exercise as a Behavioral Treatment for Cocaine Dependence	No drug interventions	treatment	Not Available	completed
NCT01822587	Enhancing Disrupted Reconsolidation: Impact on Cocaine Craving	Propranolol	treatment	2	completed
NCT02892851	Deep Brain Stimulation of the Sub-Thalamic Nucleus to Treat Severe and Treatment-resistant Cocaine Addiction.	No drug interventions	treatment	Not Available	unknown_status
NCT00729300	A Study of the Relationship Between Disulfiram and Cocaine Self-administration.	Disulfiram	basic_science	1 / 2	completed
NCT00292136	Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Study	No drug interventions	Not Available	Not Available	completed
NCT02768441	Dexamphetamine Sustained Release Pharmacokinetics and Clinical Validation of Dried Blood Spots	Dextroamphetamine	treatment	0	completed
NCT00586534	Developing Computer Based Treatments for Addiction	No drug interventions	treatment	Not Available	completed
NCT01887366	Efficacy and Safety of TV-1380 as Treatment for Facilitation of Abstinence in Cocaine-Dependent Subjects	Albumin human Butyrylcholinesterase	treatment	2	completed
NCT01067846	Cognitive Enhancement and Relapse Prevention in Cocaine Addiction	Cycloserine	treatment	Not Available	completed
NCT01929343	Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving	Lidocaine Sodium chloride	treatment	2	completed
NCT03025321	Effects of tDCS on Craving, Relapse and Cognitive Functions Among Patients With Cocaine Use Disorder	No drug interventions	treatment	Not Available	completed
NCT01984177	Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence	Corticorelin	Not Available	Not Available	completed
NCT01337297	Prefrontal Cortex Stimulation as Treatment for Crack-cocaine Addiction	No drug interventions	treatment	1 / 2	completed
NCT04336293	sTMS for Substance Use-disordered Veterans	No drug interventions	other	Not Available	completed
NCT00865332	Psychology of Reward and Punishment: Functional and Molecular Brain Imaging and Monoaminergic Correlates	No drug interventions	Not Available	Not Available	withdrawn
NCT02939352	The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol Cues	No drug interventions	basic_science	0	completed
NCT03018236	Effect of N-acetylcysteine on Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial.	Acetylcysteine Cocaine Ethanol	treatment	4	unknown_status
NCT01211418	Integrative Meditation (IM) for Cocaine Addiction	No drug interventions	treatment	Not Available	completed
NCT00626834	Vigabatrin Ph 1 Cocaine Interaction Study	Vigabatrin	basic_science	1	completed
NCT02626494	Neurobiological Adaptations and Pharmacological Interventions in Cocaine Addiction	Acetylcysteine	basic_science	4	completed
NCT01259362	Effects of Repeated Transcranial Magnetic Stimulation (rTMS) on the Treatment of Cocaine Addicted Patients	No drug interventions	treatment	2	unknown_status
NCT03423667	Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients With Cocaine Addiction	Acetylcysteine Lactose	treatment	2	recruiting
NCT01319214	Reducing Drug Craving Memories	Propranolol	treatment	Not Available	unknown_status