Malignant Pleural Mesothelioma (MPM) (DBCOND0061898)

Identifiers

Synonyms
Malignant Mesothelioma (MM) / Malignant Pleural Mesotheliomas (Mpm) / Mesothelioma, Malignant Pleural / Mesothelioma, Malignant / Malignant Mesothelioma / Malignant Mesothelioma (MPM) / Mesothelioma malignant / Malignant Pleural Mesothelioma / Pleural Malignant Mesothelioma / Malignant (Pleural) Mesothelioma / Malignant Pleural Mesotheliomas / Pleural mesothelioma malignant / Mesothelioma (malignant, clinical disorder) (disorder) / Mesothelioma malignant NOS / Mesothelioma, malignant (morphologic abnormality) / Mesothelioma of pleura / Malignant mesothelioma of pleura (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Carboplatin
A alkylating agent used to treat advanced ovarian cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05960773
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesotheliomatreatment2recruiting
NCT05375825
Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelintreatment1withdrawn
NCT05188859
First Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural Mesotheliomatreatment2not_yet_recruiting
NCT03546426
Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients with PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior Therapiestreatment1active_not_recruiting
NCT06251310
SW-682 in Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT06299163
NM32-2668 in Adult Patients With Selected Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT03654833
Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesotheliomatreatment2active_not_recruiting
NCT02357147
Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM)treatment2terminated
NCT03907852
Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancertreatment1 / 2active_not_recruiting
NCT02303899
Combination of Gemcitabine and Imatinib Mesylate in Pemetrexed-pretreated Patients With Pleural Mesotheliomatreatment2completed
NCT05324436
A Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignant Pleural Mesothelioma (MPM)No drug interventionsNot AvailableNot Availablerecruiting
NCT05455424
Niraparib Efficacy in Patient With Unresectable Mesotheliomatreatment2active_not_recruiting
NCT05568680
SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesotheliomatreatment1recruiting
NCT06051695
A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Subjects With Solid Tumors That Express MSLN and Have Lost HLA-A*02 ExpressionNo drug interventionstreatment1 / 2recruiting
NCT05698238
Clinical Study to Evaluate Safety and Dosing of CA9hu-1 in Patients With Advanced Solid TumoursNo drug interventionstreatment1not_yet_recruiting
NCT05136677
A Study to Evaluate Nivolumab in Combination With Ipilimumab Versus Pemetrexed With Cisplatin or Carboplatin for Unresectable Pleural Mesothelioma in Chinese Participantstreatment2recruiting
NCT05944237
HTL0039732 in Participants With Advanced Solid Tumourstreatment1 / 2recruiting
NCT05451849
A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancertreatment1 / 2active_not_recruiting
NCT02519049
11C-Methionine PET/CT Imaging in Patients Affected by Malignant Pleural Mesothelioma (MPM)No drug interventionsNot AvailableNot Availablecompleted
NCT05380713
......SMARTEST Trial......treatment2recruiting
NCT04981119
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell ManufacturingNo drug interventionsNot AvailableNot Availablerecruiting
NCT04823741
Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03068117
Malignant Mesothelioma - Can we Improve Quality of LifeNo drug interventionssupportive_careNot Availablecompleted
NCT03393858
Combination of Immunotherapy and Hyperthermia in Advanced Malignant MesotheliomaNo drug interventionstreatment1 / 2terminated
NCT06057935
A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesotheliomatreatment2recruiting
NCT05429866
Immunological Variables Associated to ICI Toxicity in Cancer Patientsother2recruiting
NCT04104776
A Study of CPI-0209 in Patients With Advanced Solid Tumors and LymphomasNo drug interventionstreatment1 / 2recruiting
NCT06281860
Treatment Pleural Carcinosis of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin AdministrationNo drug interventionstreatment1recruiting
NCT03502746
Phase II Nivolumab and Ramucirumab for Patients With Previously-Treated Mesotheliomatreatment2terminated
NCT06566079
Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid TumorsNo drug interventionstreatment1not_yet_recruiting
NCT00004033
Liposomal-Cisplatin Analogue (L-NDDP) in Treating Patients With Malignant Pleural MesotheliomaNo drug interventionstreatment2completed
NCT00004254
Raltitrexed in Treating Patients With Malignant Mesothelioma That Cannot Be Surgically Removedtreatment2completed
NCT00066651
Immunotoxin Therapy in Treating Patients With Advanced Solid Tumorstreatment1completed
NCT00513877
Bortezomib in Treating Patients With Malignant Pleural Mesotheliomatreatment2completed
NCT00030745
Combination Chemotherapy Before Surgery in Treating Patients With Mesothelioma of the Lungtreatment2completed
NCT00004183
Capecitabine in Treating Patients With Malignant Mesotheliomatreatment2completed
NCT00062283
Alanosine in Treating Patients With Cancertreatment2completed
NCT00024271
Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancertreatment2unknown_status
NCT01655888
The Anti-CTLA-4 Monoclonal Antibody Tremelimumab in Malignant Mesotheliomatreatment2unknown_status
NCT00253409
Combination Chemotherapy With or Without Surgery and Radiation Therapy in Treating Patients With Mesothelioma That Can Be Removed By SurgeryNo drug interventionstreatmentNot Availableunknown_status
NCT03558932
IP3R Modulation by Cancer Genes in MesotheliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00030459
Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesotheliomatreatment2unknown_status
NCT00003034
ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimentreatment3unknown_status
NCT00020124
Inhaled Doxorubicin in Treating Patients With Advanced Solid Tumors Affecting the Lungstreatment1completed
NCT01649024
A Clinical Study With Tremelimumab as Monotherapy in Malignant Mesotheliomatreatment2unknown_status
NCT00017186
Gemcitabine and Epirubicin in Treating Patients With Malignant Mesotheliomatreatment2completed
NCT03684486
Rehabilitation by Effort for Patients With Advanced Bronchial CancerNo drug interventionssupportive_careNot Availablecompleted
NCT00019825
Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleuratreatment1completed
NCT03007030
Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgerytreatment2recruiting
NCT00770120
S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgerytreatment2completed
NCT01291420
Dendritic Cell Vaccination for Patients With Solid TumorsNo drug interventionstreatment1 / 2completed
NCT00004920
Cisplatin With or Without Raltitrexed in Treating Patients With Malignant Mesothelioma of the Pleuratreatment3completed
NCT00006231
Radiation Therapy in Preventing Metastatic Cancer in Patients Who Have Diagnostic Procedures to Identify Malignant MesotheliomaNo drug interventionstreatment3completed
NCT00541073
Pemetrexed, Cisplatin, and Vitamin B12 in Treating Patients With Mesothelioma of the Chest That Cannot Be Removed by Surgerytreatment2completed
NCT00024076
Radiofrequency Ablation in Treating Patients With Refractory or Advanced Lung CancerNo drug interventionstreatment2completed
NCT00821860
Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant MesotheliomaNo drug interventionstreatment3completed
NCT00334594
Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesotheliomatreatment2completed
NCT02349412
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family CaregiversNo drug interventionssupportive_care3completed
NCT00006981
Immunotoxin Therapy in Treating Patients With Advanced Cancertreatment1completed
NCT06256055
Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid TumorsNo drug interventionstreatment1recruiting
NCT03678350
Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgerytreatment1active_not_recruiting
NCT03852823
Study of Recombinant Human Anti-PD-1 Monoclonal Antibody in Patients With Advanced TumoursNo drug interventionstreatment1unknown_status
NCT00027508
Ecteinascidin 743 in Treating Patients With Malignant Mesotheliomatreatment2terminated
NCT00003508
Antineoplaston Therapy in Treating Patients With Advanced Mesotheliomatreatment2terminated
NCT00054002
Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesotheliomatreatment2completed
NCT00898547
Biomarkers of Angiogenesis and Disease in Patients With Unresectable Malignant Mesothelioma Treated on Clinical Trial CALGB-30107No drug interventionsNot AvailableNot Availableterminated
NCT02580747
Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-mesoNo drug interventionstreatment1unknown_status
NCT00897247
Biomarkers to Detect Mesothelioma Early in Patients Exposed to Asbestos or VermiculiteNo drug interventionsNot AvailableNot Availablecompleted
NCT00634205
Phase II Study of Valproate and Doxorubicin in Malignant Mesotheliomatreatment2completed
NCT02300883
Observational Prospective Analysis of Biological Characteristics of Mesothelioma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00354393
Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesotheliomatreatment2completed
NCT00053885
PTK787/ZK 222584 in Treating Patients With Unresectable Malignant Mesotheliomatreatment2completed
NCT00733252
Optical Coherence Tomography of the Airway for Lung Cancer or Lung DiseaseNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00002475
Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancertreatment2completed
NCT00897442
Collecting Tumor Samples From Patients With Gynecological TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT00075699
Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesotheliomatreatment3completed
NCT00005636
Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgerytreatment3completed
NCT00458913
Bortezomib and Cisplatin as First-Line Therapy in Treating Patients With Malignant Mesotheliomatreatment2completed
NCT00899613
Mesothelin and Osteopontin as Diagnostic Markers in Patients With Mesothelioma or Atypical Mesothelial HyperplasiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00509041
Dasatinib in Treating Patients With Previously Treated Malignant Mesotheliomatreatment2completed
NCT00006216
Vaccine Therapy and Ganciclovir in Treating Patients With Mesotheliomatreatment1unknown_status
NCT00003263
Cisplatin, Interferon Alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesotheliomatreatment1completed
NCT01655225
A Study of LY3023414 in Participants With Advanced Cancertreatment1completed
NCT01085630
Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line Chemotherapytreatment2completed
NCT00227630
Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesotheliomatreatment2completed
NCT00002465
High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesotheliomatreatment1 / 2unknown_status
NCT00003974
Vaccine Therapy in Treating Patients With Stage I, Stage II, or Stage IIIA Non-small Cell Lung Cancer or With Stage I or Stage II Mesotheliomatreatment1completed
NCT00372840
Printed Education Materials in Patients Who Are Finishing Treatment for Stage I, Stage II, or Stage IIIA Breast Cancer, Colorectal Cancer, Prostate Cancer, or Chest CancerNo drug interventionsotherNot Availablecompleted
NCT05538572
A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid TumorsNo drug interventionstreatment1completed
NCT00006014
SU5416 in Treating Patients With Malignant Mesotheliomatreatment2completed
NCT03874455
Tazemetostat Expanded Access Program for Adults With Solid TumorsNot AvailableNot Availableno_longer_available
NCT00003723
S9810: Gemcitabine Plus Cisplatin in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot Be Removed by Surgerytreatment2completed
NCT00002608
Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumorstreatment2completed
NCT04173338
Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesotheliomatreatment1terminated
NCT00398138
Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesotheliomatreatment1completed
NCT06469138
A Phase 1 Study to Investigate 14C-bemcentinib Following Single Oral Administration in Healthy Male Subjectstreatment1completed
NCT03399552
Stereotactic Body Radiation Therapy and Avelumab Immunotherapy for Treatment of Malignant Mesotheliomatreatment1 / 2completed
NCT04214015
A Pilot Study to Explore the Role of Gut Flora in Metastatic MesotheliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05107674
A Study of NX-1607 in Adults With Advanced Malignanciestreatment1recruiting
NCT02555007
Metronomic Chemotherapy Based on Adaptative Bio-mathematical Model of Oral Vinorelbine in Patients With NSCLC or MPMtreatment1completed
NCT05228015
Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumorstreatment1active_not_recruiting
NCT02661659
A Phase Ib Trial of a Maintenance Multipeptide Vaccine (S-588210) in Patients With Unresectable Malignant Pleural Mesothelioma Without Progression After First-Line ChemotherapyNo drug interventionstreatment1withdrawn
NCT04577326
Mesothelin-targeted CAR T-cell Therapy in Patients With Mesotheliomatreatment1active_not_recruiting
NCT01773655
Clinical and Histopathologic Characteristics of BAP1 MutationsNo drug interventionsNot AvailableNot Availablecompleted
NCT01265433
Galinpepimut-S (WT-1 Analog Peptide) Vaccine in Malignant Pleural Mesothelioma After Combined Modality TherapyNo drug interventionstreatment2completed
NCT06037941
Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural MesotheliomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT00165503
Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfatediagnostic2terminated
NCT01343264
Trimodality Therapy for Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05765084
Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesotheliomatreatment1 / 2recruiting
NCT02436733
Pleurectomy/ Decortication (P/D) Preceded or Followed by Chemotherapy in Patients With Early Stage MPMtreatment2active_not_recruiting
NCT02497053
Four Versus Six Cycles of Pemetrexed/Platinum for MPMtreatment2unknown_status
NCT04201145
Pembrolizumab + Defactinib In Pleural Mesotheliomatreatment1withdrawn
NCT01143545
Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomastreatment1terminated
NCT02369198
MesomiR 1: A Phase I Study of TargomiRs as 2nd or 3rd Line Treatment for Patients With Recurrent MPM and NSCLCNo drug interventionstreatment1completed
NCT05498597
AMT-151 in Patients With Selected Advanced Solid TumoursNo drug interventionstreatment1recruiting
NCT04713761
Neoadjuvant Toripalimab Combined With Chemotherapy in the Treatment of Malignant Pleural Mesotheliomatreatment2not_yet_recruiting
NCT02397928
Safety and Efficacy of TTFields (150 kHz) Concomitant With Pemetrexed and Cisplatin or Carboplatin in Malignant Pleural Mesothelioma (STELLAR)treatment2completed
NCT00867711
Molecular Predictors of Pemetrexed and Carboplatin Response in Malignant Pleural Mesothelioma (MPM) PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02269878
Effect of FAS and FAS Ligand Polymorphisms on Patients With Platinum-Based -Treated Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01870609
Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesotheliomatreatment2terminated
NCT00386815
Safety Confirmation Study of Pemetrexed Plus Cisplatin in Patients With Malignant Pleural Mesotheliomatreatment2completed
NCT02611037
Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesotheliomatreatment2active_not_recruiting
NCT04525859
Poly-ICLC (HiltonolĀ®) Vaccine In Malignant Pleural MesotheliomaNo drug interventionstreatment1recruiting
NCT02755675
uPAR-PET for Prognostication in Patients With Non-small Cell Lung Cancer, Malignant Pleural Mesothelioma and Large Cell Neuroendocrine Carcinoma of the LungNo drug interventionsNot Available2unknown_status
NCT01211275
Standard Chemotherapy With of Without Axitinib in Malignant Mesotheliomatreatment1 / 2completed
NCT00700336
Study of CBP501 + Pemetrexed + Cisplatin on MPM (Phase I/II)treatment1 / 2completed
NCT04013334
MTG201 Plus Nivolumab in Patients With Relapsed Pleural Mesotheliomatreatment2unknown_status
NCT00165516
Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfatetreatment2completed
NCT02761863
Effect of Expression of CD74 and VEGF on Outcome of Treatment in Patients With Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT06318286
Study of Pembrolizumab Plus Chemotherapy With Lenvatinib for Malignant Pleural Mesotheliomatreatment2not_yet_recruiting
NCT04897022
A Study of Pembrolizumab and Radiation Therapy in People With Mesotheliomatreatment1recruiting
NCT05042557
Real World Study of MPM in ChinaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01098266
NGR015: Study in Second Line for Patient With Advanced Malignant Pleural Mesothelioma Pretreated With Pemetrexedtreatment3completed
NCT05308966
Observational Study in Patients With Previously Unresectable Malignant Pleural Mesothelioma Treated With Nivolumab and Ipilimumab (MESO-IMMUNE)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00652574
Dasatinib in Resectable Malignant Pleural Mesotheliomatreatment1completed
NCT05582031
Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancerstreatment2withdrawn
NCT03710876
Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesotheliomatreatment3active_not_recruiting
NCT05425576
OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint Inhibitiontreatment2not_yet_recruiting
NCT01644994
Intracavitary Cisplatin-Fibrin Localized Chemotherapy After P/D or EPP for Malignant Pleural Mesotheliomatreatment1 / 2completed
NCT02649829
Autologous Dendritic Cell Vaccination in MesotheliomaNo drug interventionstreatment1 / 2active_not_recruiting
NCT01279967
A Clinical Trial of ADI-PEG 20TM in Patients With Malignant Pleural Mesotheliomatreatment2unknown_status
NCT02662504
Intrapleural Photodynamic Therapy in a Multimodal Treatment for Patients With Malignant Pleural Mesotheliomatreatment2completed
NCT04480372
SAKK 17/18 (ORIGIN) MPM & NSCLC >1st Line Gemci & Atezo Ph IItreatment2completed
NCT03177668
Clinical Study of YS110 in Patients With Malignant Pleural MesotheliomaNo drug interventionstreatment1 / 2completed
NCT04775446
Evaluation of the Clinical/Biological Characteristics, Efficacy and Safety of Patients With Malignant Pleural Mesothelioma, Treated by ImmunotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT05508555
Effect of HITHOC After Pleurectomy Decortication for Treatment of Malignant Pleural MesotheliomaNo drug interventionstreatmentNot Availablerecruiting
NCT02497508
Nivolumab in Patients With Recurrent Malignant Mesotheliomatreatment2completed
NCT03917043
APG-2449 in Patients With Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT03715933
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomastreatment1recruiting
NCT01865045
Pharmacogenetics Of Vinorelbine In Malignant Pleural Mesothelioma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00969098
Response Evaluation in Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00571298
Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesotheliomatreatment1completed
NCT02004028
Window of Opportunity Study of VS-6063 (Defactinib) in Surgical Resectable Malignant Pleural Mesothelioma Participantstreatment2terminated
NCT00886028
Palliative Treatment With Liposomal Doxorubicin Plus Cisplatin for Patients With Malignant Pleural Mesotheliomatreatment2unknown_status
NCT05655078
Hemithoracic Irradiation With Proton Therapy in Malignant Pleural MesotheliomaNo drug interventionstreatmentNot Availablerecruiting
NCT04843007
AlvopemĀ® (Pemetrexed) Safety AssessmentNot AvailableNot Availablecompleted
NCT04162015
A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesotheliomatreatment1active_not_recruiting
NCT01243632
Gemcitabine in Long Infusion and Cisplatin for Malignant Pleural Mesothelioma Treatmenttreatment2completed
NCT04334759
DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesotheliomatreatment3active_not_recruiting
NCT05278975
Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including Mesotheliomatreatment1 / 2recruiting
NCT01722149
Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural MesotheliomaNo drug interventionstreatment0completed
NCT01721018
Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma.No drug interventionstreatment1 / 2completed
NCT00797719
Short Neoadjuvant Hemithoracic IMRT for MPMNo drug interventionstreatment1 / 2active_not_recruiting
NCT02347917
A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesotheliomatreatment1 / 2completed
NCT05660616
Switch-Maintenance Gemcitabine After First-Line Chemotherapy In Patients With Malignant Pleural Mesotheliomatreatment2completed
NCT00272558
Study of Carboplatin and Vinorelbine in Malignant Pleural Mesotheliomatreatment2completed
NCT04400539
The IMmunotherapy Pleural 5-ALA PDTtreatment2recruiting
NCT03412357
MesoTRAP: A Study Comparing Video-assisted Thoracoscopic Partial Pleurectomy/Decortication With Indwelling Pleural Catheter in Patients With Trapped Lung Due to Malignant Pleural Mesothelioma.No drug interventionstreatmentNot Availablecompleted
NCT01675765
Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesotheliomatreatment1completed
NCT01355965
Autologous Redirected RNA Meso-CIR T CellsNo drug interventionstreatment1completed
NCT03048474
Ipilimumab and Nivolumab in the Treatment of Malignant Pleural Mesotheliomatreatment2completed
NCT00280982
Dendritic Cell-based Immunotherapy in MesotheliomaNo drug interventionstreatment1completed
NCT00738582
An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural Mesotheliomatreatment2completed
NCT01353482
A Phase I/II Study of First Line Vorinostat With Pemetrexed-cisplatin, in Patients With Malignant Pleural Mesotheliomatreatment1 / 2withdrawn
NCT02194231
ATREUS - Phase II Study on the Activity of Trabectedin in Patients With Malignant Pleural Mesothelioma (MPM)treatment2completed
NCT03269227
Accelerated Hypofractionated Radiotherapy in the Treatment of Malignant Pleural MesotheliomaNo drug interventionstreatmentNot Availablerecruiting
NCT00484276
Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesotheliomatreatment2completed
NCT02049060
Study of the Combination of Tivantinib Plus Pemetrexed and Carboplatintreatment1 / 2completed
NCT02639767
Concurrent Pemetrexed/Cisplatin With Pleural Intensity Modulated Radiation Therapy for Patients With Unresectable Malignant Pleural Mesotheliomatreatment1withdrawn
NCT01212367
Intrapleural Gene Transfer for Pleural Mesotheliomatreatment1completed
NCT03175172
Evaluation of CRS-207 With Pembrolizumab in Previously Treated Malignant Pleural Mesothelioma (MPM)treatment2terminated
NCT01486368
A Phase II Study of PF-03446962 in Patients With Advanced Malignant Pleural Mesotheliomatreatment2completed
NCT01024946
Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivitytreatment2completed
NCT05795595
A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT02863055
Nintedanib as Switch Maintenance Treatment of Pleural Malignant Mesotheliomatreatment2active_not_recruiting
NCT00165555
Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesotheliomatreatment1completed
NCT01890980
Phase II Study of Adjuvant WT-1 Analog Peptide Vaccine in MPM Patients After MSK10-134No drug interventionstreatment2active_not_recruiting
NCT02672033
Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural MesotheliomaNo drug interventionstreatmentNot Availableterminated
NCT03290183
Confocal Laser Endomicroscopy in Pleural MalignanciesNo drug interventionsNot AvailableNot Availableunknown_status
NCT02959463
Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesotheliomatreatment1active_not_recruiting
NCT01064648
Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesotheliomatreatment1 / 2active_not_recruiting
NCT01112293
Anti-TGF Monoclonal Antibody (GC1008) in Relapsed Malignant Pleural Mesotheliomatreatment2completed
NCT02399371
Pembrolizumab in Treating Patients With Malignant Mesotheliomatreatment2active_not_recruiting
NCT03126630
Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesotheliomatreatment1 / 2active_not_recruiting
NCT01241682
Dendritic Cell-based Immunotherapy Combined With Low-dose Cyclophosphamide in Patients With Malignant Mesotheliomatreatment1completed
NCT03233724
Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomastreatment1 / 2terminated
NCT02603315
Vascularity Impact on the Treatment Outcome in Malignant Pleural Mesothelioma(VITMPM)No drug interventionsNot AvailableNot Availablecompleted
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