Secondary Progressive Multiple Sclerosis (SPMS)

Also known as: Secondary Multiple Sclerosis, Progressive / Multiple Sclerosis, Secondary Progressive / Secondary-progressive Multiple Sclerosis / Secondary Progressive MS (SPMS) / Secondary Progressive MS / Secondary Progressive Multiple Sclerosis / Secondary progressive multiple sclerosis (disorder)

DrugDrug NameDrug Description
DB00087AlemtuzumabA monoclonal anti-CD52 antibody used in the treatment of B-cell chronic lymphocytic leukemia and relapsing forms of multiple sclerosis.
DB00068Interferon beta-1bA form of recombinant human interferon used to slow the progression of relapsing multiple sclerosis and to reduce the frequency of clinical symptoms.
DB01204MitoxantroneA chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
DB00108NatalizumabA monoclonal anti-integrin antibody used to treat Crohn's disease or multiple sclerosis.
DB09122Peginterferon beta-1aAn interferon beta used to treat relapsing forms of multiple sclerosis.
DrugDrug NamePhaseStatusCount
DB06215Ferumoxytol0Completed1
DB12091Gadolinium0Completed1
DB00597Gadoteridol0Completed1
DB00331Metformin0Recruiting1
DB06769Bendamustine1Not Yet Recruiting1
DB16170Foralumab1Withdrawn1
DB00279Liothyronine1Completed1
DB00166Lipoic acid1Completed1
DB00108Natalizumab1Completed1
DB00073Rituximab1Completed1
DB05767Andrographolide1 / 2Unknown Status1
DB06576Baminercept1 / 2Withdrawn1
DB11105Benzalkonium1 / 2Completed1
DB15726Human Umbilical Cord Mesenchymal Stem Cells1 / 2Completed1
DB00030Insulin human1 / 2Completed1
DB00594Amiloride2Completed1
DB01285Corticotropin2Terminated1
DB00151Cysteine2Recruiting1
DB01184Domperidone2Completed1
DB04573Estriol2Unknown Status1
DB00472Fluoxetine2Completed1
DB01611Hydroxychloroquine2Recruiting1
DB05266Ibudilast2Completed1
DB00808Indapamide2Recruiting1
DB00555Lamotrigine2Completed1
DB00331Metformin2Recruiting1
DB00108Natalizumab2Completed1
DB00717Norethisterone2Unknown Status1
DB00740Riluzole2Completed1
DB00641Simvastatin2Completed2
DB14547Chloride ion2 / 3Recruiting1
DB00242Cladribine2 / 3Recruiting1
DB04921Dirucotide2 / 3Completed1
DB04921Dirucotide2 / 3Terminated1
DB05259Glatiramer2 / 3Completed1
DB11988Ocrelizumab2 / 3Completed1
DB00073Rituximab2 / 3Completed1
DB12371Siponimod2 / 3Completed1
DB00316Acetaminophen3Recruiting1
DB00087Alemtuzumab3Recruiting1
DB00242Cladribine3Recruiting1
DB06637Dalfampridine3Completed1
DB08908Dimethyl fumarate3Terminated1
DB04921Dirucotide3Terminated1
DB00950Fexofenadine3Recruiting1
DB11526Masitinib3Completed1
DB00959Methylprednisolone3Recruiting1
DB01204Mitoxantrone3Terminated1
DB00108Natalizumab3Recruiting1
DB00108Natalizumab3Terminated1
DB11988Ocrelizumab3Recruiting2
DB06650Ofatumumab3Recruiting1
DB00073Rituximab3Recruiting2
DB00641Simvastatin3Active Not Recruiting1
DB12371Siponimod3Completed1
DB18715Tolebrutinib3Active Not Recruiting1
DB11850Ublituximab3Recruiting1
DB06637Dalfampridine4Completed1
DB12371Siponimod4Completed1
DB09150Fludeoxyglucose (18F)Not AvailableCompleted1
DB05259GlatiramerNot AvailableRecruiting1
DB00068Interferon beta-1bNot AvailableCompleted2
DB12371SiponimodNot AvailableCompleted1
DB08880TeriflunomideNot AvailableRecruiting1