Agents Against Leishmaniasis and Trypanosomiasis
- Agents Against Leishmaniasis and Trypanosomiasis
- Accession Number
- ATC Classification
Drug Drug Description Nitrofural A topical antibacterial for the prevention and treatment of bacterial infections of the skin. Pentamidine An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. Suramin For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms. Sodium stibogluconate For the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment... Eflornithine A medication used topically to reduce unwanted facial hair growth in women. The postulated mechanism of action is through irreversible inhibition of ornithine decarboxylase (ODC) in the skin. Nifurtimox An antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection). Benznidazole A trypanocidal agent used to treat Chagas disease. Melarsoprol Melarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis). Meglumine antimoniate Not Annotated Acetarsol An anti infective used to treat a wide variety of infections in the body. Fexinidazole An orally bioavailable 2-substituted 5-nitroimidazole used to treat early- and late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense. Miltefosine An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type.
- Drugs & Drug Targets