Accession Number

Not Available

DrugDrug Description
PicrotoxinUsed internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.
BenzthiazideFor the treatment of high blood pressure and management of edema.
FenfluramineFenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures.
ModafinilA stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder.
DiethylpropionAn appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction.
SibutramineA norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity.
EtryptamineDeveloped in the 1960's for use as an antidepressant before market withdrawal in 1962.
FenproporexFenproporex is used as an appetite suppressant, and anti-obesity agent [2]; however, due to substance abuse potential, it is an illicit substance in many countries. In some countries, such as...
IndopanIndopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention...
Drugs & Drug Targets
PicrotoxinGamma-aminobutyric acid receptor subunit rho-1target
PicrotoxinGamma-aminobutyric acid receptor subunit alpha-1target
PicrotoxinGlycine receptor subunit alpha-2target
PicrotoxinGlycine receptor subunit alpha-3target
PicrotoxinCytochrome P450 1A1enzyme
PicrotoxinGlutamine synthetaseenzyme
PicrotoxinGlycine receptor subunit alpha-1target
BenzthiazideSolute carrier family 12 member 3target
BenzthiazideCarbonic anhydrase 1target
BenzthiazideCarbonic anhydrase 2target
BenzthiazideCarbonic anhydrase 4target
BenzthiazideCarbonic anhydrase 9target
BenzthiazideCarbonic anhydrase 12target
BenzthiazideCarbonic anhydrasetarget
Fenfluramine5-hydroxytryptamine receptor 2Ctarget
Fenfluramine5-hydroxytryptamine receptor 2Btarget
FenfluramineCytochrome P450 2D6enzyme
FenfluramineSodium-dependent serotonin transportertarget
Fenfluramine5-hydroxytryptamine receptor 2Atarget
Fenfluramine5-hydroxytryptamine receptor 1Dtarget
FenfluramineSigma non-opioid intracellular receptor 1target
Fenfluramine5-hydroxytryptamine receptor 1Atarget
FenfluramineCytochrome P450 1A2enzyme
FenfluramineCytochrome P450 2B6enzyme
FenfluramineCytochrome P450 2C9enzyme
FenfluramineCytochrome P450 2C19enzyme
FenfluramineCytochrome P450 3A4enzyme
FenfluramineCytochrome P450 3A5enzyme
ModafinilSodium-dependent dopamine transportertarget
ModafinilAlpha-1B adrenergic receptortarget
ModafinilCytochrome P450 3A4enzyme
ModafinilCytochrome P450 2C19enzyme
ModafinilCytochrome P450 1A2enzyme
ModafinilCytochrome P450 2B6enzyme
ModafinilCytochrome P450 2C9enzyme
ModafinilCytochrome P450 3A5enzyme
ModafinilCytochrome P450 2D6enzyme
DiethylpropionSodium-dependent noradrenaline transportertarget
DiethylpropionSodium-dependent dopamine transportertarget
SibutramineSodium-dependent serotonin transportertarget
SibutramineSodium-dependent noradrenaline transportertarget
SibutramineCytochrome P450 3A4enzyme
SibutramineSodium-dependent dopamine transportertarget