NCT02069028
Effectiveness of Different Interventions for Implementing Surviving Sepsis Campaign (SSC) Guidelines on Compliance and Mortality: Systematic Review and Meta-analysis No drug interventions Not Available Not Available unknown_status NCT04102371
Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis treatment 3 recruiting NCT00313365
Surgical Lavage vs Serial Needle Aspiration for Infected Joints No drug interventions treatment 3 withdrawn NCT04404387
Lessening Organ Dysfunction With VITamin C in Septic ARDS treatment 3 recruiting NCT00457613
Effects of Alkaline Phosphatase on Renal Function in Septic Patients treatment 2 completed NCT06619535
Sepsis As a Cause of Death Among Elderly Cancer Patients No drug interventions Not Available Not Available completed NCT02979951
Fosfomycin I.v. for Treatment of Severely Infected Patients No drug interventions Not Available Not Available recruiting NCT04540094
Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital treatment 3 completed NCT06624436
Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia No drug interventions treatment 4 not_yet_recruiting NCT05469048
Near Patient Molecular Testing in Sepsis No drug interventions Not Available Not Available completed NCT06624618
Rapid Molecular Diagnosis of Sepsis in the Intensive Care Unit No drug interventions Not Available Not Available recruiting NCT06473844
Efficacy of SGLT2 Inhibitors in Adults With Sepsis No drug interventions other Not Available not_yet_recruiting NCT06626984
Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis No drug interventions basic_science 1 / 2 not_yet_recruiting NCT04635878
INFLAmmasomes NLRP3 in Platelets and Leukocytes During SEPSIS in Intensive Care Unit No drug interventions Not Available Not Available completed NCT05181696
Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia No drug interventions Not Available Not Available recruiting NCT05955612
Use of Procalcitonin, a Blood Test to Guide Antibiotic Therapy for Sepsis in Adults No drug interventions health_services_research 3 completed NCT05975671
Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis No drug interventions other Not Available recruiting NCT06103500
Integrated Clinical Decision Support for Empiric Antibiotic Selection in Sepsis No drug interventions treatment Not Available recruiting NCT06117605
Sepsis Electronic Prompting for Timely Intervention and Care for Emergency Department Patients No drug interventions health_services_research Not Available completed NCT06117618
Sepsis Electronic Prompting for Timely Intervention and Care for Inpatients No drug interventions health_services_research Not Available completed NCT06267742
Clinical Trial to Evaluate MDW for Early Detection of Sepsis No drug interventions Not Available Not Available recruiting NCT06271031
Process Mapping and Data Collection to Inform a Computer Simulation Model of Hospitalised Patients With Bloodstream Infection, Sepsis and Systemic Infection No drug interventions Not Available Not Available recruiting NCT06319248
Use of Midodrine in Septic Shock Patients treatment 2 / 3 recruiting NCT06612307
Sensitivity and Specificity of Leucocytes Subpopulation Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Observational Clinical Trial No drug interventions Not Available Not Available not_yet_recruiting NCT06373159
An Observational Study to Learn About the Occurrence of Disseminated Intravascular Coagulation Among Adults With Sepsis in Japan No drug interventions Not Available Not Available active_not_recruiting NCT06512129
Defining Volume Status in Sepsis with Extracellular Water Measurement No drug interventions Not Available Not Available not_yet_recruiting NCT06613256
Characterisation of Endothelial Cells in Different Inflammatory Pathologies No drug interventions Not Available Not Available recruiting NCT06539884
Does the Phoenix Pediatric Sepsis Prognosis Prediction Scale Work No drug interventions Not Available Not Available recruiting NCT06545838
Renin Levels as Prognostic Indicators of Septic Shock Severity and Outcome No drug interventions Not Available Not Available not_yet_recruiting NCT06562803
Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With HBV-ACLF and Sepsis No drug interventions treatment Not Available not_yet_recruiting NCT06570187
The Effect of Dexmedetomidine on the Renal Functions in Septic Critically Ill Patients supportive_care 4 not_yet_recruiting NCT06586372
CRP,CRP/Alb Ratio, N/L Ratio in Predictors of Both Systemic Infection and Survival in Patient with Sepsis in Assiut University Hospitals No drug interventions Not Available Not Available not_yet_recruiting NCT06596096
Risk Factors for Beta-lactam Target Non Attainment in Critically Ill Patients BETALACTACRIT No drug interventions Not Available Not Available recruiting NCT06602245
Clearance of Antibacterial Agents During Hemoperfusion in Patients With Sepsis No drug interventions Not Available Not Available not_yet_recruiting NCT03913403
Study of Treatment's Echocardiographic Mechanisms No drug interventions Not Available Not Available unknown_status NCT03237403
Hospital Orientation Since SAMU Regulation Centre Call No drug interventions Not Available Not Available unknown_status NCT06305403
VEXUS and NGAL in the Diagnosis and Prognosis of Sepsis-associated Acute Kidney Injury No drug interventions Not Available Not Available not_yet_recruiting NCT05052203
Researching the Effects of Sepsis on Quality Of Life, Vitality, Epigenome and Gene Expression During RecoverY From Sepsis No drug interventions Not Available Not Available enrolling_by_invitation NCT05544903
Point of Care Ultrasound to Predict Intensive Care Unit Admission of Patients Presenting With Sepsis to the Emergency Department No drug interventions Not Available Not Available recruiting NCT01236703
Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICU No drug interventions Not Available Not Available completed NCT05044403
Evaluation of the Efficacy and Safety of Extracorporeal Support With Hemoperfusion in Critical Patients With Multiorgan Dysfunction Syndrome by Septic Origin No drug interventions other 4 unknown_status NCT04103203
Fast Assay for Pathogen Identification - Quasi-Experimental Intervention Study No drug interventions diagnostic Not Available completed NCT03952390
Effect of Renin-Angiotensin System on Platelet in Patient With Sepsis No drug interventions Not Available Not Available completed NCT02544490
Defining Circulating Micro-RNA Biomarkers for the Early Diagnosis and Prognosis of Sepsis No drug interventions Not Available Not Available completed NCT05633290
CharacterisatiON of carDiac funCTion in Intensive Care Unit Survivors of Sepsis. No drug interventions Not Available Not Available recruiting NCT06461390
The Effect of Early Norepinephrine on Stroke Volume Index, Cardiac Index, Lactate, and Arterial Elastance in Pediatric Septic Shock treatment 2 / 3 completed NCT03213990
Beta-Lactam InfusioN Group Study No drug interventions treatment Not Available completed NCT02738164
SEPSIS 3 Critera for Risk Stratification in Emergency Patients No drug interventions Not Available Not Available completed NCT00049764
Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis treatment 3 completed NCT06261164
Population Pharmacokinetic Model of Amikacin and Vancomycin in Critically Ill Patients No drug interventions Not Available Not Available recruiting NCT04711564
The Effects of Different Lipid Emulsions on the Adipokines in Critically Ill Patients With Sepsis No drug interventions Not Available Not Available completed NCT03966664
Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients No drug interventions Not Available Not Available unknown_status NCT02424721
Sepsis Assessment in Belgian Emergency Rooms No drug interventions Not Available Not Available terminated NCT01434121
Ascorbic Acid (Vitamin C) Infusion in Human Sepsis treatment 1 / 2 completed NCT01649921
The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis treatment 3 completed NCT04552821
Study of Biomarkers in Patients of Sepsis Complicated With Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available unknown_status NCT05304221
A Prospective Cluster-Randomized, Controlled Crossover Trial to Validate an Electronic "Resistance Calculator" No drug interventions Not Available Not Available recruiting NCT06426121
Clinical Validation of BACTEC™ Plus Aerobic/F Culture Vials Compared With Equivalent Product No drug interventions Not Available Not Available recruiting NCT00130221
Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections prevention 1 completed NCT02120521
Serum STREM and MNDA Mointoring in ICU No drug interventions Not Available Not Available completed NCT00979121
Statins for Acutely Injured Lungs From Sepsis treatment 3 terminated NCT03113721
Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis No drug interventions Not Available Not Available unknown_status NCT00548002
Combination Therapy With Fluoroquinolone in Staphylococcus Aureus Bacteremia Not Available Not Available completed NCT06521502
The APS Phenotyping Study No drug interventions Not Available Not Available recruiting NCT02560402
The Relation Between the Renal Resistive Index and Glomerular Hyper Filtration No drug interventions Not Available Not Available completed NCT02079402
Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care No drug interventions treatment 4 completed NCT02127502
VENUS: Septic Gene Expression Using SeptiCyte No drug interventions Not Available Not Available completed NCT04644302
Circulatory Coherence in COVID-19 and Non-COVID-19 Patients With Sepsis No drug interventions Not Available Not Available completed NCT03379402
Sepsis-3 Study in Northeast Thailand No drug interventions Not Available Not Available recruiting NCT04203784
Meropenem and Piperacillin Plasma Concentrations During CRRT No drug interventions Not Available Not Available completed NCT05900284
Safety and Feasibility of Metformin for Sepsis Induced AKI treatment 2 enrolling_by_invitation NCT03968484
Platelet Transfusion in Sepsis Trial No drug interventions treatment Not Available withdrawn NCT00189384
Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants treatment 3 unknown_status NCT01976884
Expression and the Clinical Significance of Neutrophil PD-L1 During Sepsis No drug interventions Not Available Not Available completed NCT01503684
Biomarkers in Exhaled Breath Condensates of Septic Patients to Predict Development of Multi-organ Dysfunction Syndrome No drug interventions Not Available Not Available unknown_status NCT05950984
Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK) No drug interventions Not Available Not Available recruiting NCT05602584
Effect of Immunophenotype on Prognosis of Sepsis No drug interventions Not Available Not Available enrolling_by_invitation NCT06287684
Molecular Endotype-Specific Dynamics of Lung Endothelial Barrier Integrity in Sepsis No drug interventions Not Available Not Available recruiting NCT03734484
Gram Type Infection-Specific Sepsis Identification Using Machine Learning No drug interventions diagnostic 2 withdrawn NCT04118179
New Strategy to Predict Early Sepsis No drug interventions Not Available Not Available active_not_recruiting NCT04255979
A Study of HY209 in Healthy Male Volunteers for Sepsis No drug interventions treatment 1 completed NCT02957279
Dendritic Cells-Derived Exosomes in Human Sepsis No drug interventions Not Available Not Available unknown_status NCT04438187
Trial of Antimicrobial Restraint in Presumed Pneumonia No drug interventions treatment Not Available completed NCT03001687
Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic Patients No drug interventions prevention Not Available unknown_status NCT03454087
Study of Early Enteral Dextrose in Sepsis No drug interventions treatment Not Available completed NCT05210387
Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections No drug interventions treatment Not Available terminated NCT01023087
Renal Impairment Associated With Colistin Levels Not Available Not Available completed NCT02684487
Vitamin D Status in Patients With Severe Sepsis prevention 3 withdrawn NCT00037687
Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis treatment 3 terminated NCT00307333
Impact of Heart Rate Characteristics Monitoring in Neonates No drug interventions diagnostic Not Available completed NCT04567433
Days Alive and Out of Hospital for Patients With Sepsis Not Available Not Available completed NCT06013033
DDX17 Orchestrate Septic Vascular Endothelial Pyroptosis by Controlling Gasdermin D Pore Formation No drug interventions Not Available Not Available not_yet_recruiting NCT01739933
The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure prevention 3 completed NCT04529733
Evaluation of the IB10 Sphingotest PCT+ in a Point-of-Care Setting No drug interventions diagnostic Not Available unknown_status NCT05684133
REMISE Study: REMnant Biospecimen Investigation in SEpsis No drug interventions Not Available Not Available completed NCT03355833
Comparing Prognostic Performance of SEPSIS 2 and SEPSIS 3 Strategies at the Emergency Service No drug interventions Not Available Not Available completed NCT05023954
mSEP: Testing of Physiological and Immune-metabolic Blood Markers for Maternal Sepsis No drug interventions Not Available Not Available unknown_status NCT04280354
Molecular Biomarkers for Sepsis No drug interventions Not Available Not Available terminated NCT01530854
Plasma Free Fatty Acids in Risk Assessment of Sepsis in the Emergency Department: A Prospective Pilot Study No drug interventions Not Available Not Available completed NCT05094154
Effect of Antibiotic Choice On ReNal Outcomes (ACORN) treatment 4 completed NCT03015454
An Algorithm Driven Sepsis Prediction Biomarker No drug interventions screening Not Available completed NCT02647554
Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China treatment 4 completed NCT02266654
Early Goal Directed Therapy in Sepsis by Emergency Medical Services No drug interventions treatment Not Available withdrawn NCT06548854
A Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Dose Exploration Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetic Characteristics of STC314 Injection Administered Intravenously in Sepsis Patients No drug interventions treatment 2 active_not_recruiting NCT03782454
Quantification of Bacterial DNA in Sepsis No drug interventions Not Available Not Available unknown_status NCT05443854
Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01) No drug interventions treatment 3 unknown_status NCT02927054
Effect of Education on Resident Physician Knowledge of Sepsis No drug interventions health_services_research Not Available completed NCT05774054
The Impact of Early Norepinephrine Administration on Outcomes of Patients With Sepsis-induced Hypotension treatment Not Available completed NCT02616354
Preliminary Research On Two-step Dosing Of Imipenem/Cilastatin treatment 4 unknown_status NCT01539551
Investigation of the Role of Brain Natriuretic Peptide and Lactate in Early Goal-directed Therapy for Patients With Severe Sepsis and Septic Shock No drug interventions Not Available Not Available unknown_status NCT00814151
MicroPhage S. Aureus / MSSA / MRSA Blood Culture Beta Trial No drug interventions Not Available Not Available completed NCT05336851
Emergency PWAS in Respiratory Infectious Disease No drug interventions Not Available Not Available recruiting NCT04493151
Imipenem/Cilastatin/Relebactam PK in ECMO other 1 completed NCT02565251
Volemic Resuscitation in Sepsis and Septic Shock No drug interventions treatment Not Available unknown_status NCT04961151
Working Toward the Advancement of Recovery Using Modulated Therapeutic Hyperthermia (WARMTH) in Sepsis - Pilot No drug interventions treatment Not Available withdrawn NCT04610853
Rotational Thromboelastometry Versus DIC Score in Sepsis No drug interventions Not Available Not Available recruiting NCT04839653
Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria prevention Not Available unknown_status NCT01828853
Maternal and Neonatal Outcomes After Membrane Sweeping No drug interventions Not Available Not Available unknown_status NCT06253377
Continuous Renal Replacement Therapy With Oxiris in Acute Kidney Injury and Sepsis No drug interventions Not Available Not Available active_not_recruiting NCT03489577
The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients No drug interventions Not Available Not Available terminated NCT04525677
Gut Microbiome Dysbiosis in Sepsis-induced Coagulopathy No drug interventions Not Available Not Available unknown_status NCT05287477
Passive Evaluation in Operational Environment of the AI Clinician Decision Support System for Sepsis Treatment No drug interventions Not Available Not Available recruiting NCT03431077
A Study of LJPC-501 in Pediatric Patients With Hypotension treatment 2 completed NCT00633477
Efficacy and Safety of Resatorvid in Patients With Sepsis-induced Cardiovascular and Respiratory Failure treatment 3 terminated NCT00490477
The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial No drug interventions prevention 3 completed NCT03752047
Can Respiratory Rate Predict the Risk of Deterioration of Septic Patients No drug interventions Not Available Not Available completed NCT02734147
High Dose Intravenous Ascorbic Acid in Severe Sepsis treatment 2 terminated NCT06446947
Identification of Markers of Poor Clinical Prognosis in Sepsis by Epigenetic Analysis No drug interventions Not Available Not Available not_yet_recruiting NCT00407147
Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of Infection No drug interventions treatment 4 terminated NCT01683747
Single Dose Enteral Tranexamic Acid in Critically Ill Patients treatment 2 terminated NCT00197847
Infection Surveillance in Intensive Care Patients No drug interventions Not Available Not Available unknown_status NCT03715647
Correlation of Survival in Puerperae by Electrical Impedance Tomography No drug interventions Not Available Not Available completed NCT05469347
Alirocumab in Patients With Sepsis treatment 1 recruiting NCT02536547
Diagnostic Value of Pulmonary Ultrasound in the Diagnosis of Ventilator-associated Pneumoniae No drug interventions Not Available Not Available completed NCT01751945
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project No drug interventions prevention Not Available completed NCT06009445
Renal Resistive Index as a Predictor of Acute Kidney Injury and Evaluation of Fluid Administration in Sepsis No drug interventions Not Available Not Available recruiting NCT05143645
A New Protocol for Continuous Vancomycin Infusion Dosing. No drug interventions Not Available Not Available completed NCT02378545
Trial of Hyperoxic O2 Therapy vs. Normoxic O2 Therapy in Sepsis treatment 4 completed NCT03728998
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis No drug interventions screening Not Available completed NCT05558098
Dapagliflozin in Patients With Critical Illness treatment 3 completed NCT01396798
Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E. No drug interventions Not Available Not Available completed NCT02922998
CD64 and Antibiotics in Human Sepsis No drug interventions Not Available Not Available unknown_status NCT05584098
Modified Early Warning Score (MEWS) and Quick Sequential Organ Failure Assessment (qSOFA) in the Emergency Room No drug interventions screening Not Available completed NCT03406598
Bedside Visual Analysis of Sublingual Microcirculation in Shock Patients No drug interventions Not Available Not Available unknown_status NCT04068298
Temperature Gradients for Sepsis Severity and Fluid Resuscitation No drug interventions Not Available Not Available unknown_status NCT06124105
Can Urinary Partial Oxygen Pressure be an Indicator of Acute Kidney Injury in Patients With Sepsis? No drug interventions diagnostic Not Available not_yet_recruiting NCT02567305
Neutrophil Extracellular Traps and Neonatal (PV4991) & Pediatric Sepsis (PV5063) No drug interventions Not Available Not Available unknown_status NCT01191905
Effects of HIgh Volume COntinuous REnal Replacement Therapy in Patients With Septic Acute Kidney Injury No drug interventions treatment Not Available completed NCT02400697
Placental Transfusion Project for Preterm Infants No drug interventions Not Available Not Available completed NCT03540797
Myeloid-derived Suppressor Cells in Sepsis No drug interventions Not Available Not Available unknown_status NCT00294697
Genetic Variation and Immune Responses After Injury No drug interventions Not Available Not Available unknown_status NCT04881097
Cognitive Function and Health-related Quality of Life After Neuro-intensive Care No drug interventions Not Available Not Available withdrawn NCT04280497
Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis No drug interventions treatment Not Available recruiting NCT06377397
Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates No drug interventions treatment 3 not_yet_recruiting NCT02707497
The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia treatment 2 / 3 recruiting NCT03829683
Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis treatment 2 completed NCT03811483
SepsisFLAGS ( FLuidAndGender) No drug interventions Not Available Not Available unknown_status NCT00792883
Clinical Protocol Validation to Identify Prognostic Markers for Critical Care Pediatric Patients No drug interventions Not Available Not Available completed NCT05283083
Decatecholaminisation of Septic Shock With Dexmedetomidine and In-hospital Mortality treatment 2 completed NCT01128283
Indicators of Inflammation and Coagulation in Sepsis No drug interventions Not Available Not Available completed NCT00889083
Hepatic Mitochondrial Function in Sepsis No drug interventions Not Available Not Available withdrawn NCT04409561
Reference Range for abioSCOPE® Device With the PSP Assay in a Generally Healthy Adult Population No drug interventions Not Available Not Available completed NCT01089361
Immunomodulatory Properties of Ketamine in Sepsis treatment 1 / 2 completed NCT06381661
Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial treatment 3 not_yet_recruiting NCT05394961
Factors Associated With Decisions to Withhold or Withdraw Intensive Care No drug interventions Not Available Not Available completed NCT02898961
Impact of 30 mg/kg Amikacin and 8 mg/kg Gentamicin on Serum Concentrations in Critically Ill Patients With Severe Sepsis treatment 4 completed NCT05190861
Evaluation of Droplet Digital PCR Rapid Detection Method and Precise Diagnosis and Treatment for Suspected Sepsis No drug interventions diagnostic Not Available unknown_status NCT04332861
Evaluation of Infection in Obstructing Urolithiasis No drug interventions Not Available Not Available completed NCT03145428
Evaluation of Monocyte Volume Distribution Width (MDW) for Early Detection of Sepsis No drug interventions Not Available Not Available completed NCT05914428
Biomarkers to Predict Acute Respiratory Distress Syndrome(ARDS) in Patients With Sepsis No drug interventions Not Available Not Available recruiting NCT03237728
Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients No drug interventions treatment 1 completed NCT00273728
BaSES Trial: Basel Starch Evaluation in Sepsis treatment 4 completed NCT03982628
ICU Sarcopenia Rates by Abdominal CT: Sepsis vs. Trauma No drug interventions Not Available Not Available unknown_status NCT01890928
Gluconeogenesis Rates and Its Precursors in Pediatric Sepsis No drug interventions Not Available Not Available completed NCT05692011
AN69ST Verse PS in CBP in Septic Children No drug interventions Not Available Not Available not_yet_recruiting NCT02533011
Evaluation of the Heparin Binding Protein Levels in Sepsis No drug interventions Not Available Not Available completed NCT00143611
Efficacy & Safety of Resatorvid in Adults With Severe Sepsis treatment 3 completed NCT01262911
Effect of SRT2379 on Endotoxin-Induced Inflammation No drug interventions basic_science 1 completed NCT00410111
Pathogenesis and Cerebrovascular Manifestations of Septic Encephalopathy No drug interventions Not Available Not Available completed NCT01426711
Critical Care Excellence in Sepsis and Trauma No drug interventions Not Available Not Available completed NCT06295393
Renin Angiotensin Aldosterone System In Septic Kids No drug interventions Not Available Not Available recruiting NCT05612893
Discover the Immune Signature of Sepsis Caused by Acute Pulmonary Infection: A Cohort Study No drug interventions Not Available Not Available not_yet_recruiting NCT00333593
Super High-Flux - High Volume Dialysis in Sepsis-Induced Acute Renal Failure No drug interventions treatment 1 / 2 completed NCT03683693
Procalcitonin to Guide Antibiotic Stop in Neurocritical Care Patients. No drug interventions diagnostic Not Available unknown_status NCT03235193
Predictive algoRithm for EValuation and Intervention in SEpsis No drug interventions diagnostic Not Available completed NCT04427371
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis No drug interventions Not Available Not Available unknown_status NCT05922371
ObsErvational Study of the Practical Cinical UTility of the NuQ.® H3.1 Nucleosome Levels in Adult Patients With Sepsis to Facilitate Early Diagnosis and Prognostication. (EPICETUS) No drug interventions Not Available Not Available recruiting NCT04541771
The Role of Lactobacillus Reuteri in Preventing Necrotizing Enterocolitis (NEC) in Pre-term Infants prevention 2 unknown_status NCT02469571
Modulation of Gut Microbiota in Early Sepsis: A Pilot Study No drug interventions prevention Not Available completed NCT04458571
Effect of CRRT Duration on Solute Removal No drug interventions Not Available Not Available completed NCT02855671
Infrared Imaging in Septic Illness No drug interventions Not Available Not Available completed NCT04140578
Antibiotic Prophylaxis in Patients Undergoing GVO prevention 4 recruiting NCT02858778
Timing of Acute Palliative Care Consultation in Critically Ill Patients No drug interventions supportive_care Not Available unknown_status NCT00133978
Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients No drug interventions treatment Not Available completed NCT06028178
Droplet Digital PCR Combines With Transcriptome Analysis in Early Warning of Sepsis in the Emergency Department No drug interventions Not Available Not Available not_yet_recruiting NCT03950778
The Effect of Albumin Supplementation on the Inflammatory and Oxidative Stress Markers in Septic Patients treatment 0 unknown_status NCT03734978
Association Between Different Blood Groups and Sepsis in Preterm Infants No drug interventions Not Available Not Available unknown_status NCT01244178
Hyperinsulinemic Therapy in Sepsis treatment Not Available unknown_status NCT00190788
Extended Therapy of Drotrecogin Alfa (Activated) 4 vs 7 Days Infusion treatment 3 completed NCT03167788
Red Cell Rejuvenation for the Attenuation of Transfusion Associated Organ Injury in Cardiac Surgery No drug interventions prevention 2 withdrawn NCT04582188
The Early Coagulopathy for the Prognosis in Sepsis No drug interventions Not Available Not Available unknown_status NCT00745888
Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit No drug interventions Not Available Not Available unknown_status NCT04829188
Comparative Effectiveness of Readmission Reduction Interventions for Individuals With Sepsis or Pneumonia No drug interventions health_services_research Not Available recruiting NCT04353388
Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Washington University No drug interventions Not Available Not Available completed NCT04580888
Emergency Echocardiography in Sepsis No drug interventions treatment Not Available recruiting NCT02980588
The Effects of SGC on Glucose Control in Critically Ill Patients With Sepsis No drug interventions treatment Not Available unknown_status NCT06312488
Point of Care Evaluation of Fibrinolysis in Sepsis No drug interventions diagnostic Not Available recruiting NCT04513288
ICITRU : Randomized Trial of Immunonutrition With L-citrulline in Patients Hospitalized in Intensive Care for Sepsis or Septic Shock No drug interventions treatment Not Available recruiting NCT00042588
A Safety and Efficacy Study of Hospitalized Patients With Community-Acquired Pneumonia and Sepsis No drug interventions treatment 2 completed NCT02130388
The Impact of Zinc Supplementation on Innate Immunity and Patient Safety in Sepsis No drug interventions other Not Available terminated NCT05502107
Impact of a Prehospital Sepsis Protocol on Timely Antibiotic Administration and Subsequent Adverse Events No drug interventions health_services_research Not Available recruiting NCT05495607
Continous Renal Replacement Therapy With the CARPEDIEM® in a French National Cohort of 25 Neonates and Small Infants No drug interventions Not Available Not Available completed NCT06063707
The Effect of rTEM in the Prognosis and Severity of Sepsis Induced ARDS No drug interventions Not Available Not Available not_yet_recruiting NCT02933307
Continuous Monitoring on the General Ward No drug interventions prevention Not Available completed NCT02711709
Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty No drug interventions Not Available Not Available active_not_recruiting NCT01328509
Zinc and Inflammation in Sepsis No drug interventions Not Available Not Available completed NCT04825509
Ultrasound-Assessed Diaphragmatic Dysfunction as a Predictor of Weaning Outcome No drug interventions Not Available Not Available completed NCT04434209
A Study Looking at the Use of Biomarkers to Provide Early Indication of Acute Kidney Injury in Patients With Sepsis (Limiting AKI Progression In Sepsis) No drug interventions diagnostic 4 terminated NCT02180009
Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis No drug interventions Not Available Not Available completed NCT00518609
Prevention of Infection in Indian Neonates - Phase I Observational Study No drug interventions Not Available Not Available completed NCT03654456
Impact of Sleep Apnea on Sepsis Mortality No drug interventions Not Available Not Available unknown_status NCT06099756
Discharge Readmission Analysis and Management in Sepsis (DReAMS-2) No drug interventions Not Available Not Available recruiting NCT01788956
Comparison of Central Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter No drug interventions Not Available Not Available unknown_status NCT05109156
Preoperative Sepsis Timeline, Profile and Its Association With Recipient Outcome Following Live Donor Liver Transplant No drug interventions Not Available Not Available unknown_status NCT00487656
Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation treatment 2 completed NCT00397956
To Evaluate the Treatment Effect of an Anti-Infective Agent for Complicated Infections (0826-053) treatment 3 completed NCT06116656
Changes in Host Gene Expression to Differentiate Between Systemic Inflammation and Infection After Major Surgery No drug interventions Not Available Not Available not_yet_recruiting NCT02960256
The Impact of Infectious Disease on QT Segment No drug interventions Not Available Not Available completed NCT04533256
Effects of Renal Replacement Therapy With Hemoadsoption in Patients With Sepsis No drug interventions Not Available Not Available completed NCT05094856
Effects of Fluid Therapy on Peripheral TIssse Perfusion During Sepsis/Septic Shock No drug interventions Not Available Not Available completed NCT05217485
Continuous Ambulatory Cardiac Monitoring for Recurrent Atrial Fibrillation After Sepsis No drug interventions diagnostic Not Available unknown_status NCT06253585
Precision Resuscitation With Crystalloids in Sepsis No drug interventions treatment Not Available recruiting NCT02843685
Regression Discontinuity Design to Evaluate of Drotrecogin Alpha Effectiveness Not Available Not Available completed NCT03831685
Blood Lactate Level for Pre-hospital Orientation of Septic Shock No drug interventions Not Available Not Available unknown_status NCT04282785
Point-of-care Monitoring of Antibiotic Concentration in Blood With UV-VIS Absorption Spectroscopy No drug interventions Not Available Not Available active_not_recruiting NCT06326385
Machine Learning Predictive Models for Sepsis Risk in ICU Patients With Intracerebral Hemorrhage No drug interventions Not Available Not Available not_yet_recruiting NCT00707785
Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis No drug interventions treatment 3 completed NCT03320785
Circulating Markers in Preterm Infants With Perinatal and Neonatal Inflammation No drug interventions Not Available Not Available terminated NCT02743585
Impact of Rapid Pathogen Identification From Blood Cultures (RABbIT) No drug interventions diagnostic Not Available unknown_status NCT02288715
Relationship of Cerebral Perfusion Pressure Variability to Sepsis-associated Encephalopathy No drug interventions Not Available Not Available completed NCT05810415
Use of Renin Versus Lactic Acid as Tissue Perfusion Biomarkers for Mortality Prediction in Hypotensive Critically Ill Patients No drug interventions Not Available Not Available recruiting NCT01012115
Coagulation Factors, Cytokines and Tissue Injury Markers in Sepsis No drug interventions Not Available Not Available completed NCT00493415
The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis treatment 3 completed NCT00252915
Reconstruction of Monocytic Immunocompetence by Granulocyte-macrophage-colony Stimulating Factor (GM-CSF) in Patients With Severe Sepsis and Septic Shock No drug interventions treatment 2 completed NCT03531515
Predictors of Reactive Thrombocytosis in Critically Ill Septic Patients No drug interventions Not Available Not Available unknown_status NCT02204215
Electric Acupuncture for ICU-acquired Weakness in Mechanical Ventilation Patients No drug interventions treatment Not Available unknown_status NCT05725837
Effects of Paroxetine on Cardiovascular Function in Septic Patients treatment 2 recruiting NCT00568737
The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death treatment 3 completed NCT00389337
Sepsis: Prognosis and Evaluation of Early Diagnosis and Intervention (SPEEDI Study) No drug interventions Not Available Not Available unknown_status NCT04182737
Efficacy and Safety of Therapy With IgM-enriched Immunoglobulin With a Personalized Dose vs Standard Dose in Patients With Septic Shock. treatment 3 unknown_status NCT05961137
Orange Park Out-of-Hospital Quality Improvement Study for Improving CMS Sepsis Core Measures No drug interventions health_services_research Not Available completed NCT01530932
Immune Activation, Hypoxia and Vasoreaction in Sepsis of Pulmonary Versus Abdominal Origin No drug interventions Not Available Not Available completed NCT04063332
Functionality of Endogenous Biological Clock in Sepsis No drug interventions Not Available Not Available recruiting NCT02936232
Severe Sepsis and Septic Shock Registry No drug interventions Not Available Not Available recruiting NCT04990232
Personalized Immunotherapy in Sepsis treatment 2 active_not_recruiting NCT03014232
Comparison Cytokine Clearance Between SLED-f Using High Cut-off Dialyzer and High-flux Dialyzer in Septic AKI Patients No drug interventions treatment Not Available completed NCT04800952
Pharmacokinetics of Antibiotics in Critically Ill Patients Receiving CVVHF No drug interventions other Not Available unknown_status NCT03217552
The Performance of the Mologic Biomarker Panel in Infection No drug interventions Not Available Not Available unknown_status NCT03768752
Diastolic Dysfunction and Interstitial Lung Edema in Septic Patients No drug interventions Not Available Not Available completed NCT06007352
Use of Antibiotic Based Irrigation for Ureteroscopic Treatment of Urolithiasis prevention 2 not_yet_recruiting NCT04157452
Prediction of Sepsis After Flexible Ureteroscopy No drug interventions Not Available Not Available completed NCT06354452
Effect of Statin Therapy on Sepsis-related Mortality in Intensive Care Unit Patients No drug interventions Not Available Not Available completed NCT03506152
Evaluation of Serum Procalcitonin in Critically Ill Patients With Suspected Sepsis No drug interventions Not Available Not Available completed NCT01511952
A Multi-Site Study of Music Therapy Interventions on Vitals, Feeding and Sleep in Premature Infants No drug interventions supportive_care Not Available completed NCT02739152
TRIAGE: TRIage of Sepsis At emerGency dEpartment No drug interventions Not Available Not Available completed NCT06541600
Risk Factors for Adverse Outcomes in Sepsis No drug interventions Not Available Not Available completed NCT00449800
Pharmacokinetic of Ceftriaxone in Septic ICU Patients treatment 4 unknown_status NCT03628300
Neurotoxicity Evaluation of Beta-lactams in Intensive Care Unit and Identification of the Risk Factors No drug interventions Not Available Not Available completed NCT00430859
Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis treatment 2 completed NCT04969159
The Degree, Duration and Frequency of Insulin Resistance in Non-operated Patients With Sepsis No drug interventions Not Available Not Available completed NCT02656459
Longitudinal Gene Expression Profiling in Adults After Traumatic Injury No drug interventions Not Available Not Available completed NCT01708759
IL8 Monitoring and Its Correlation With 251-gene Polymorphism No drug interventions Not Available Not Available completed NCT01632059
Examination of ADMA Serum Level and DDAH II No drug interventions Not Available Not Available completed NCT02530359
Pirfenidone Effect on the Recovery of Renal Function in Septic Acute Kidney Injury treatment 4 unknown_status NCT02706275
Pilot Trial of External Warming in Septic Patients No drug interventions treatment Not Available completed NCT06523075
Host Dysregulation-Driven Sepsis Prediction Model No drug interventions Not Available Not Available not_yet_recruiting NCT06278675
Multiple Study of Electroaccpuncture in ARDS No drug interventions treatment Not Available not_yet_recruiting NCT00005775
Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants treatment 3 completed NCT01447875
The Effects of Sedative on the Fluid Responsiveness in Critically Ill Patients prevention 1 completed NCT03369275
Cellular Immunotherapy for Septic Shock treatment 2 unknown_status NCT04974775
Swecrit Biobank - Blood Samples From Critically Ill Patients and Healthy Controls No drug interventions Not Available Not Available active_not_recruiting NCT03031275
Long-term Follow Up of Adult Patients Treated With Extracorporeal Membrane Oxygenation for Respiratory Failure No drug interventions other Not Available completed NCT03066375
Respiratory Variations For Predicting Fluid Responsiveness 2 No drug interventions diagnostic Not Available completed NCT04721275
Evaluation of the Performance of Sepsis Predictive Scores on the Elderly Population in the Emergency Department. No drug interventions Not Available Not Available unknown_status NCT02106975
Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury treatment 2 completed NCT00609375
Efficacy of Cefepime Continuous Infusion Versus an Intermittent Dosing Regimen treatment 4 completed NCT01411670
Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock. treatment 2 completed NCT00922870
Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock No drug interventions treatment Not Available completed NCT06360770
Assessement of Microcirculation With NIRS Predicts Sepsis Development in Patients With Severe Covid-19 Pneumonia No drug interventions Not Available Not Available completed NCT04716842
Evaluation of Plasma Angiotensin II and Angiotensin II Receptor Levels in Patients With Sepsis and Septic Shock: a Prospective Observational Study. No drug interventions Not Available Not Available unknown_status NCT03238742
The Efficacy of Xuebijing Injection on Sepsis No drug interventions treatment 4 completed NCT04803942
Clinical Intuition for PRedicting Evolution in Sepsis in the Emergency Department - CIPRES-ED Study No drug interventions Not Available Not Available unknown_status NCT03129542
Midodrine Hydrochloride in Early Sepsis treatment 1 completed NCT05596942
Evaluating the Efficacy of Channa Striata in Stabilizing eNOS in Patients With Septic. No drug interventions supportive_care 3 completed NCT02180399
Serial Measurement of Capillary Blood Lactate in the Management of Sepsis No drug interventions Not Available Not Available unknown_status NCT04105699
Evaluation of Immunoassay Measurements of Pancreatic Stone Protein Performed on abioSCOPE® Device With the PSP Assay on ICU Patients at Risk of Sepsis as an Aid in Identifying Sepsis No drug interventions Not Available Not Available completed NCT04963699
The Study of NT-proBNP Combined With HS-cTnT in Evaluating the Prognosis of Sepsis No drug interventions Not Available Not Available completed NCT04289506
Validation of Molecular and Protein Biomarkers in Sepsis No drug interventions Not Available Not Available unknown_status NCT03334006
Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis treatment 2 recruiting NCT00583206
Muscle Atrophy in Sepsis No drug interventions Not Available Not Available withdrawn NCT06109506
Towards a Tailored Approach for Patients With Acute Diverticulitis and Abscess Formation. A Multicenter Cohort Analysis No drug interventions Not Available Not Available recruiting NCT03153306
Importance of the Infusion Rate for the Plasma Expanding Effect of 5% Albumin in the Septic Patient treatment 4 unknown_status NCT00879606
Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome No drug interventions treatment 2 completed NCT05112406
Early Diagnostic Biomarkers of Sepsis No drug interventions Not Available Not Available unknown_status NCT03356249
Next-Generation Sequencing Diagnostics of Bacteremia in Sepsis No drug interventions Not Available Not Available completed NCT00942149
An Open Label Study to Describe the Pharmacokinetics of Daptomycin in Infants treatment 1 completed NCT03340649
The Predictive Value of Hepatocyte Growth Factor and Soluble Receptor s-Met in Sepsis No drug interventions Not Available Not Available unknown_status NCT05731349
Impact of Early Sepsis Care Guided by the National Early Warning Score 2 in the Emergency Department No drug interventions treatment Not Available completed NCT04189549
Preclinical Detection of Sepsis Early in Hospitalized Patients Following Surgery, Injury or Severe Illness No drug interventions Not Available Not Available unknown_status NCT01264536
Pilot Study: Lactoferrin for Prevention of Neonatal Sepsis No drug interventions prevention 2 completed NCT05146336
CytOSorb TreatMent Of Critically Ill PatientS Registry No drug interventions Not Available Not Available recruiting NCT03730636
Procalcitonin and Duration of AntiBiotherapy In Late Onset Sepsis of Neonate No drug interventions treatment Not Available completed NCT06368336
Health Related Quality of Life After Intensive Care for Sepsis, a National Cohort Study. No drug interventions Not Available Not Available completed NCT05192213
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock treatment 3 terminated NCT03350113
Hemospec Device for Sepsis Diagnosis No drug interventions diagnostic Not Available completed NCT01099813
Sepsis Pathophysiological & Organisational Timing No drug interventions Not Available Not Available completed NCT04612413
A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients treatment 2 active_not_recruiting NCT02782013
Study of Progression of Community Acquired Pneumonia in the Hospital No drug interventions Not Available Not Available completed NCT05142813
A Blood Test to Diagnose Sepsis in Symptomatic Adults and Children No drug interventions Not Available Not Available unknown_status NCT05912413
Predicton of Sepsis Recovery Performance Subtypes Pilot Study No drug interventions Not Available Not Available recruiting NCT06376318
Shock and Acute Conditions OutcOmes Platform No drug interventions Not Available Not Available active_not_recruiting NCT05244018
Outcome of High Dose Vitamin D on Prognosis of Sepsis Requiring Mechanical Ventilation treatment 4 completed NCT05930418
Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis No drug interventions diagnostic Not Available recruiting NCT01241318
Zambia Chlorhexidine Application Trial prevention 2 / 3 completed NCT02883218
Dynamic Alterations of Th2/Th1 With New Onset of Community-acquired Severe Sepsis Patients No drug interventions Not Available Not Available completed NCT05825118
N\L Ratio Versus L\A Ratio as a Predictor of Morbidity and Mortality in Sepsis and Septic Shock No drug interventions Not Available Not Available recruiting NCT03621618
Clinical Assessment of Arterial Dynamic Elastance in ICU Patients, Dependent on Inotropic or Vasopressor Drugs. No drug interventions diagnostic Not Available unknown_status NCT02185118
Effects of Subanesthetic Isoflurane/Sevoflurane in 60% Oxygen on Clinical In-vitro Experimental Sepsis treatment Not Available unknown_status NCT04094818
HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis No drug interventions Not Available Not Available recruiting NCT04570618
Early Prediction of Sepsis No drug interventions diagnostic Not Available completed NCT04921319
De-resuscitation Informed by Ultrasound for Patients With Sepsis No drug interventions treatment Not Available unknown_status NCT04576819
Role and Mechanisms of Lipid and Lipoprotein Dysregulation in Sepsis No drug interventions Not Available Not Available completed NCT03090919
The INFUSE Trial - Intervening With Platelet Transfusions in Sepsis No drug interventions treatment Not Available withdrawn NCT00698919
Bacterial Infection Diagnosis Using Blood DNA No drug interventions Not Available Not Available unknown_status NCT02203019
Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure treatment 4 completed NCT01263041
Effect of L-arginine and Glutamine on Preterm prevention 2 / 3 completed NCT03714841
C-reactive Protein Information and Blood Cultures for Emergency Department Patients With Sepsis No drug interventions treatment Not Available unknown_status NCT03744741
HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study No drug interventions Not Available Not Available completed NCT04773717
The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In Sepsis treatment Not Available completed NCT03767517
A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders No drug interventions supportive_care Not Available completed NCT00488917
Sepsis, Endothelial Function, and Lipids in Critically Ill Patients With Liver Failure (the SELLIFA Study) No drug interventions Not Available Not Available completed NCT04291417
Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Baylor S&W No drug interventions Not Available Not Available completed NCT05148117
Mitochondrial Dysfunction Contributes to Sepsis Induced Cardiac Dysfunction No drug interventions Not Available Not Available not_yet_recruiting NCT01014117
Effect of SRT2104 on Endotoxin-induced Inflammation basic_science 1 completed NCT01920217
Identification Sepsis Related Single Nucleotide Polymorphism (SNP) by Whole Exome Sequencing No drug interventions Not Available Not Available unknown_status NCT02721134
Diagnostic Performance of a New Bio-marker During Bacterial Sepsis No drug interventions diagnostic Not Available completed NCT01535534
Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis No drug interventions Not Available Not Available unknown_status NCT01753024
Pancreatic Exocrine Insufficiency and Pancreatic Enzyme Supplementation in Critically Ill Adult Patients No drug interventions Not Available Not Available completed NCT02871024
Efficacy of Polymyxin B Hemoperfusion on Severe Sepsis Secondary to Pneumonia or Urinary Tract Infection No drug interventions treatment Not Available terminated NCT01490424
TREM-1 Gene Polymorphisms No drug interventions Not Available Not Available completed NCT00187824
Regulation of Endocrine, Metabolic, Immune and Bioenergetic Responses in Sepsis No drug interventions Not Available Not Available unknown_status NCT05095324
The Biomarker Prediction Model of Septic Risk in Infected Patients No drug interventions Not Available Not Available unknown_status NCT04033224
Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure No drug interventions Not Available Not Available recruiting NCT05591924
Early Severe Illness TrAnslational BioLogy InformaticS in Humans No drug interventions Not Available Not Available not_yet_recruiting NCT04203524
Procalcitonin and Antimicrobial Utilization in Critically Ill Cancer Patients With Sepsis No drug interventions diagnostic Not Available unknown_status NCT01724424
Melatonin in Healthy Volunteers basic_science 1 completed NCT02312024
International Registry on the Use of the CytoSorb Adsorber No drug interventions Not Available Not Available unknown_status NCT06061224
The Influences of Early Mobilization on Myokines, Body Composition and Outcomes in ICU Septic Patients No drug interventions supportive_care Not Available recruiting NCT04134624
EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock No drug interventions treatment Not Available terminated NCT02304224
the Relationship of the Use of Eye Masks and Outcomes of Patients With Sepsis in Intensive Care Unit No drug interventions supportive_care Not Available unknown_status NCT05208216
Neuromuscular Stimulation Versus Intermittent Compression for Venous Thromboembolism Prophylaxis in Critical Care No drug interventions prevention Not Available recruiting NCT05630716
Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or Septic Shock No drug interventions supportive_care Not Available recruiting NCT01449916
Simplified Severe Sepsis Protocol in Zambia No drug interventions treatment Not Available terminated NCT06067516
Effects of Fluid Resuscitation on Capillary Refilling Time and Organ Functions in Septic Shock No drug interventions Not Available Not Available recruiting NCT00799916
Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis treatment 3 completed NCT00819416
Fluid Resuscitation in Early Septic Shock treatment 2 completed NCT03708796
DIAGNOSis of Infection in Emergency Department No drug interventions Not Available Not Available completed NCT05578196
Fecal Microbial Transplantation in Critically Ill Patients With Severe Infections. No drug interventions treatment Not Available recruiting NCT05647096
Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating cfDNA/NETs in Subjects With Sepsis No drug interventions treatment Not Available not_yet_recruiting NCT01528358
Tissue Near InfraRed Spectroscopy (NIRS) in Critically Ill Patients No drug interventions Not Available Not Available completed NCT02771158
Midodrine During Recovery From Septic Shock supportive_care 4 withdrawn NCT00839358
Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation prevention 4 completed NCT02325258
Assessment of a Proposed Microbiological Alert and Its Impact on a Sepsis Campaign No drug interventions diagnostic Not Available completed NCT00948558
Citrate Pharmacokinetics and Regional Citrate Anticoagulation in CRRT No drug interventions Not Available Not Available unknown_status NCT00510835
Protocolized Care for Early Septic Shock No drug interventions treatment Not Available completed NCT00908635
The Role of Angiopoietin, Tie-2, and Vascular Endothelial Growth Factor (VEGF) in Sepsis-Induced Multiple Organ Dysfunction Syndrome (MODS) No drug interventions Not Available Not Available unknown_status NCT02053935
Impact of Dopamine Infusion on Insulin Secretion in Healthy Subjects treatment 1 completed NCT05076435
Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients No drug interventions treatment 2 completed NCT05849935
abioSCOPE PSP Reference Range Study; Extension of AB-PSP-003 No drug interventions Not Available Not Available completed NCT03876535
Performance Evaluation of the Nanomix eLab® CRP, PCT, and LAC Assays With the Nanomix eLab System No drug interventions Not Available Not Available completed NCT01724463
Electronic Application of a Severe Sepsis Screening Tool and Management Bundle No drug interventions Not Available Not Available unknown_status NCT05383963
Evaluation of Parameters Collected From Routine Data for the Diagnosis of Sepsis and Septic Shock and Their Influence on Time to Diagnosis and Patient Outcome No drug interventions Not Available Not Available recruiting NCT05367986
Electro-acupuncture at Zusanli, Qihai, and Guanyuan Acupoints Regulate Immune Function in Patients With Sepsis No drug interventions treatment Not Available completed NCT03914586
The Membrane Adsorbing OXiris Filter in Septic Patients With AKI No drug interventions Not Available Not Available unknown_status NCT06010186
Evolution of Muscle Function, Breathlessness and Quality of Life Following Intra or Extra-Abdominal Sepsis in ICU Patients No drug interventions other Not Available recruiting NCT02569086
Piperacillin PK Analysis in Severe Sepsis Patients No drug interventions Not Available Not Available completed NCT02143986
Glycosylated Ferritin in Macrophagic Activation Syndromes No drug interventions Not Available Not Available unknown_status NCT03835286
Vitamin C to Reduce Vasopressor Dose in Septic Shock treatment 3 withdrawn NCT04855786
External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients No drug interventions treatment Not Available active_not_recruiting NCT04620486
Effect of BPA on Anchor Antibiotic Continuity in the ED: Randomized Controlled Trial No drug interventions treatment Not Available completed NCT05357339
Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock No drug interventions treatment Not Available unknown_status NCT04643639
Assessing the Effects of CytoSorb Hemoperfusion on the Development on Immunoparalysis No drug interventions treatment 3 completed NCT00995839
Terlipressin in Septic Shock: Effects on Microcirculation treatment 2 / 3 completed NCT06078839
Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy treatment 4 not_yet_recruiting NCT06514339
Evidence-based Evaluation and Mechanism of Shenhuang Granules in the Treatment of Sepsis No drug interventions treatment 0 not_yet_recruiting NCT06181422
Metformin and Lactoferrin in Sepsis in Icu prevention 2 / 3 recruiting NCT05042622
Organ-substituting Technologies in the Treatment of Heart and Pulmonary Failure No drug interventions treatment Not Available unknown_status NCT04111822
Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock treatment 3 completed NCT05623722
Erector Spinae Plane Block Improves Organ Dysfunction in Septic Patients With Acute Gastrointestinal Injury No drug interventions treatment Not Available recruiting NCT06524622
VExUS Combined With CVP to Predict Clinical Outcomes in Sepsis Participants No drug interventions Not Available Not Available recruiting NCT04861922
Unfractioned Heparin for Treatment of Sepsis Caused by Abdominal Infection treatment 3 recruiting NCT02159222
Sepsis Trial of Early Physical Therapy Outside the ICU No drug interventions treatment Not Available terminated NCT03842722
Insufficient Oxygenation in Septic Patients No drug interventions Not Available Not Available completed NCT00608322
Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis treatment 3 completed NCT03013322
Anticholium® Per Se treatment Not Available completed NCT03588325
Evaluation of MDW for Early Detection of Sepsis, Clinical Validity No drug interventions Not Available Not Available completed NCT01388725
Comparison the Value of Several Biomarkers of Sepsis No drug interventions Not Available Not Available completed NCT00806325
Clinical Factors Associated With the Development of Severe Sepsis in Patients Being Treated for Acute Myeloid Leukemia No drug interventions Not Available Not Available completed NCT03095625
Role of Thromboelastography in Septic Shock No drug interventions Not Available Not Available unknown_status NCT05921825
Red Cell Distribution Width and Lactate Albumin Ratio as Prognostic Markers for Mortality in Sepsis and Septic Shock No drug interventions Not Available Not Available not_yet_recruiting NCT06253325
Early Detection of At-risk Septic Patients No drug interventions Not Available Not Available recruiting NCT06006325
Electroacupuncture Modulates SPMs Metabolism and Respiratory Symptoms in Patients With Sepsis Complicating ARDS No drug interventions treatment Not Available recruiting NCT04048525
Cytokine Removal With CVVHD Compared to CVVH No drug interventions supportive_care Not Available completed NCT02701725
Compensatory Reserve Index as a Hemodynamic Status Evaluation Tool in Patients No drug interventions Not Available Not Available unknown_status NCT03295825
Heparin Binding Protein in Early Sepsis Diagnosis No drug interventions diagnostic Not Available completed NCT04260230
Remote Monitoring of Patients at Risk of Sepsis No drug interventions other Not Available unknown_status NCT04226430
Effect of Cytosorb on Blood Levels of Inflammatory Biomarkers of Sepsis. No drug interventions Not Available Not Available completed NCT05616130
Pathological Myeloid Activation After Sepsis and Trauma No drug interventions Not Available Not Available recruiting NCT05090930
Innovative Technologies for the Treatment of Pulmonary and Heart Failure No drug interventions treatment Not Available unknown_status NCT04816630
Feasibility Study of Hematology Parameters in COVID-19 Disease No drug interventions Not Available Not Available completed NCT05604430
Pre-hospital Ventilation Clinical Study No drug interventions Not Available Not Available enrolling_by_invitation NCT01155830
Inflammatory Cytokine Quantification in Infants No drug interventions Not Available Not Available completed NCT02327130
Changes in Exhaled 13CO2/12CO2 Breath Delta Value as an Early Indicator of Infection in ICU Patients No drug interventions diagnostic Not Available completed NCT02544230
Granulocyte Transfusions in Hematological Patients With Febrile Neutropenia No drug interventions Not Available Not Available completed NCT03837730
Citrulline and Arginase Activity in Severe Sepsis and Septic Shock No drug interventions Not Available Not Available unknown_status NCT06294730
COronary Microcirculation and Troponin Elevation in Septic Shock No drug interventions Not Available Not Available recruiting NCT00559130
Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis No drug interventions treatment Not Available completed NCT00360048
Oxytocin Effects on Cytokines and Endocrine Parameters After LPS Induced Systemic Inflammatory Effects in Healthy Volunteers Not Available Not Available completed NCT00698048
Serial Vasopressin and Copeptin Levels in Children With Sepsis and Septic Shock No drug interventions Not Available Not Available completed NCT06390748
Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes treatment 2 completed NCT00027248
Safety and Efficacy of MBI 226 for the Prevention of Central Venous Catheter-Related Bloodstream Infections prevention 3 completed NCT05118048
StatStrip Lactate, Hemoglobin, and Hematocrit Meter in Whole Blood No drug interventions Not Available Not Available terminated NCT04448548
Possible Roles of MDW in Infection Management in Emergency Care No drug interventions Not Available Not Available completed NCT02094248
rhTPO in Critical Patients With Thrombocytopenia No drug interventions treatment 2 / 3 unknown_status NCT03797157
Human Milk Fortification in Extremely Preterm Infants No drug interventions prevention 2 / 3 active_not_recruiting NCT05634057
Efficacy of Anisodamine Hydrobromide Combined With Low-molecular-weight Heparin in the Treatment of Patients With Sepsis treatment Not Available enrolling_by_invitation NCT05942157
Therapeutic Drug Monitoring in Patients With Difficult-to-Treat Gram-Negative Bacterial Infections No drug interventions treatment Not Available recruiting NCT00825357
Biological Markers to Identify Early Sepsis and Acute Lung Injury No drug interventions Not Available Not Available completed NCT05507957
Impact of Blood Culture Positivity Time on Clinical Management of Pediatric ICU Patients No drug interventions Not Available Not Available not_yet_recruiting NCT01104857
Respiratory Muscle Dysfunction in Critically Ill Patients No drug interventions basic_science Not Available unknown_status NCT04823026
Host RNA Profiles to Detect Infections in Young Infants No drug interventions Not Available Not Available completed NCT01580826
Pasteurization of Mother's Own Milk for Preterm Infants No drug interventions prevention Not Available completed NCT01431326
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care Not Available Not Available completed NCT01578226
Procalcitonin in Cirrhotic Patients at High Risk for Sepsis No drug interventions Not Available Not Available completed NCT01099566
The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation treatment 4 completed NCT00250666
Procalcitonin-Guided Antimicrobial Discontinuation No drug interventions diagnostic 4 completed NCT06491966
Clinical Outcomes and Inflammatory Responses in Viral vs. Bacterial Sepsis No drug interventions Not Available Not Available recruiting NCT01936766
Optimal Fluid Management in Adult Severe Malaria No drug interventions Not Available Not Available completed NCT01114165
Value of the LightCycler® SeptiFast Test MGRADE for the Pathogen Detection in Neutropenic Hematological Patients No drug interventions diagnostic 4 completed NCT03452865
Esomeprazole to Reduce Organ Failure in Sepsis treatment 3 completed NCT05410665
The Roles of IL-9/E-cadherin and Ferroptosis in Intestinal Mucosal Barrier Injury in Sepsis No drug interventions Not Available Not Available unknown_status NCT01709565
Lactate Clearance According to the Presence of Hepatic Dysfunction No drug interventions Not Available Not Available unknown_status NCT02910765
Methylene Blue and Ozone in Early Sepsis supportive_care 4 unknown_status NCT03019965
Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis treatment Not Available completed NCT04615065
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine No drug interventions Not Available Not Available recruiting NCT01182974
Paracetamol Toxicity in Septic Patients Not Available 3 suspended NCT03152474
Adrenal Cortical Function and Vitamin A Deficiency in Sepsis treatment 4 completed NCT01397474
Peripheral Perfusion Targeted Fluid Management No drug interventions supportive_care 4 unknown_status NCT03597074
Doppler Ultrasound for Prediction of Reversibility of Acute Kidney Injury in Septic ICU Patients No drug interventions Not Available Not Available completed NCT00486174
Methylene Blue in Sepsis: A Randomized Controlled Trial treatment Not Available withdrawn NCT05688774
Study of Progression of Community Acquired Pneumonia in the Hospital in Patients With More Severe Preexisting Diseases and Immunosuppression No drug interventions Not Available Not Available recruiting NCT03270774
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units No drug interventions Not Available Not Available completed NCT01775020
Dose-response Study of Arginine Supplementation in Severe Sepsis No drug interventions Not Available 0 completed NCT04445220
A Study of Cell Therapy in COVID-19 Subjects With Acute Kidney Injury Who Are Receiving Renal Replacement Therapy treatment 1 / 2 unknown_status NCT05083520
Incidence of Cereblon in Intensive Care Patients No drug interventions Not Available Not Available unknown_status NCT05893420
A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning No drug interventions prevention Not Available recruiting NCT03938220
Electrical Cardiometry Compared to Transthoracic Echocardiography in Fluid Responsiveness in Sepsis No drug interventions Not Available Not Available completed NCT02336620
Balanced Salt Solution VS. Normal Saline Solution in Septic Shock No drug interventions treatment 3 completed NCT06157320
Clinical Research on Shenfu Injection in Septic Patients treatment Not Available recruiting NCT01891682
Methionine Metabolism in Parenterally Fed Pediatric Sepsis No drug interventions Not Available Not Available completed NCT02748382
Fluids in Sepsis and Septic Shock No drug interventions treatment 2 / 3 completed NCT00629382
Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis No drug interventions treatment 4 completed NCT00303082
Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity prevention 3 terminated NCT00800631
The Biomarker and Cardiac Function in Sepsis No drug interventions Not Available Not Available unknown_status NCT06531031
Clinical Performance Study of Microbio InfectID-BSI for Detection of Bacteria and Yeast With Patient Blood Samples No drug interventions Not Available Not Available not_yet_recruiting NCT00803231
Follow-up Data of Patients Treated With XIGRIS® in France No drug interventions Not Available Not Available completed NCT02346331
Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya No drug interventions treatment Not Available completed NCT02837731
Fluid Responsiveness Evaluation in Sepsis-associated Hypotension No drug interventions treatment Not Available completed NCT03869073
Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study) treatment 2 unknown_status NCT02478073
Piperacillin Pharmacokinetics in ICU Patients No drug interventions Not Available Not Available unknown_status NCT00141973
Time Course of Procalcitonin and C Reactive Protein in Septic Patients Under Treatment With Corticosteroids No drug interventions Not Available Not Available completed NCT02163473
Hypoxia Inducible Factor 1 Alpha as a Novel Biomarker in Septic Shock No drug interventions Not Available Not Available completed NCT00451373
Acute Renal Failure in the Surgical Intense Care Units - NTUH-SICU-ARF (NSARF) Study treatment Not Available unknown_status NCT03598127
Vitamin A Status in Critically Ill Children With Sepsis and Its Association With Illness Severity No drug interventions Not Available Not Available unknown_status NCT03344627
Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients treatment Not Available completed NCT01947127
Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department No drug interventions Not Available Not Available completed NCT00873327
Pharmacokinetics and Safety of Piperacillin-tazobactam in Neonates other 1 completed NCT04055727
Sepsis at Södersjukhuset-Adherence to Treatment Guidelines No drug interventions Not Available Not Available unknown_status NCT00034476
A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients With Severe Sepsis No drug interventions treatment 1 / 2 completed NCT04991376
Specific miRNAs in Sepsis and Nephrotoxic Antibiotic Treatment No drug interventions Not Available Not Available completed NCT00254176
Cysteine Supplementation in Critically Ill Neonates No drug interventions treatment 2 / 3 unknown_status NCT04758676
BIA Assessment of Polymyoneuropathy in Critically Ill Patients No drug interventions diagnostic Not Available recruiting NCT03882476
RCT of Sepsis Machine Learning Algorithm No drug interventions diagnostic 2 withdrawn NCT01416376
Effect of Multiple Dose Levels of SRT2379 on Endotoxin-Induced Inflammation No drug interventions basic_science 1 completed NCT02319876
Expression of TIM-3 on Lymphocytes in Sepsis No drug interventions Not Available Not Available unknown_status NCT05627076
Analytical Validation of the abioSCOPE Device With the IVD CAPSULE PSP Test: Comparison of PSP Values Measured With Venous Whole Blood and Those Measured With Arterial Whole Blood. No drug interventions Not Available Not Available completed NCT05157360
HAT for the Treatment of Sepsis Associated With NASTI treatment 1 / 2 terminated NCT04155060
The Prognostic Value of Lactate is Different Among Septic Patients No drug interventions Not Available Not Available completed NCT04933760
CV-SQuISH-ED: Clinical Validation Study No drug interventions Not Available Not Available unknown_status NCT02829060
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 prevention Not Available recruiting NCT00045760
The Study of Drotrecogin Alfa (Activated) in a Subpopulation of Adult Patients With Severe Sepsis treatment 4 completed NCT03584594
Presepsin in the Diagnosis of Sepsis in Critically Ill Patients No drug interventions Not Available Not Available completed NCT01551394
Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis treatment 3 completed NCT03406494
Efficacy and Safety of a Multicomponent Physical Therapy Program in Mechanically Ventilated Patient With Sepsis No drug interventions prevention Not Available unknown_status NCT00121394
Chlorhexidine Vaginal and Infant Wash in Pakistan No drug interventions treatment 3 completed NCT01085994
Procalcitonin Monitoring May Decrease Antibiotic Use in the Intensive Care Unit No drug interventions Not Available Not Available unknown_status NCT05849194
Role of Early Point of Care Ultrasound in Management of Sepsis in Emergency Department No drug interventions diagnostic Not Available completed NCT04683094
Comparative Study for the Validity of Various Severity Scoring System No drug interventions Not Available Not Available completed NCT00004494
Phase I Study of Vasoactive Intestinal Peptide in Patients With Acute Respiratory Distress Syndrome and Sepsis treatment 1 completed NCT05707494
Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Sepsis No drug interventions treatment Not Available recruiting NCT03884894
Neonatal Sepsis Diagnosis: ; PCR Commercial Technique and Blood Culture No drug interventions Not Available Not Available completed NCT03992794
Assessment of Disease Severity, Progression and Treatment in Infected Patients Presenting to the Emergency Department No drug interventions Not Available Not Available completed NCT05980494
Lung Ultrasound Score and Inferior Vena Cava Diameter Compared to Pulse Pressure Variation No drug interventions diagnostic Not Available recruiting NCT03550794
Thiamine as a Renal Protective Agent in Septic Shock treatment 2 completed NCT00599794
A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status No drug interventions Not Available Not Available completed NCT00282594
The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit treatment Not Available completed NCT02054091
Feeding Bovine Colostrum to Preterm Infants No drug interventions supportive_care Not Available completed NCT03673891
Evaluation of Fluid Infusion With LifeFlow for Patients With Suspected Septic Shock No drug interventions treatment Not Available withdrawn NCT00197691
Botswana Pediatric Respiratory Disease and Bloodstream Infection Study No drug interventions Not Available Not Available completed NCT00113191
Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants No drug interventions prevention Not Available completed NCT04565691
Bacteremia From Periodontal Treatment to Elucidate the Underpinnings of Sepsis No drug interventions treatment Not Available recruiting NCT03066362
Respiratory Variations for Predicting Fluid Responsiveness No drug interventions diagnostic Not Available completed NCT06142162
To Develop an Algorithm for Predicting the Unfavorable Course of Sepsis in Children Based on a Comprehensive Assessment of Immunological, Biochemical and Molecular Genetic Markers No drug interventions Not Available Not Available recruiting NCT04606862
A Clinical Trial to Evaluate the Efficacy of the Morley Medical Sepsis (MMS) Software Device in Predicting Sepsis in Adult Patients Using Artificial Intelligence (AI) Machine Learning Algorithms No drug interventions diagnostic Not Available unknown_status NCT01619462
Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Children treatment 3 unknown_status NCT05806762
Prediction of Rehospitalization Following a Sepsis Admission Using a Wearable Biopatch No drug interventions Not Available Not Available recruiting NCT01013662
Lipid Profile in Patients With Severe Sepsis or Septic Shock Under Strict or Liberal Glycemic Control No drug interventions screening Not Available completed NCT02455180
Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients treatment 4 completed NCT05842980
BIomarkers to Predict the Outcomes of Sepsis No drug interventions Not Available Not Available recruiting NCT00528580
Statins for the Early Treatment of Sepsis treatment 2 terminated NCT02963480
Investigation of Inflammatory Parameters in a Perioperative Closed-meshed Standard Progress in CPB Patients No drug interventions Not Available Not Available completed NCT06238180
Personalised Real-time Interoperable Sepsis Monitoring (PRISM) No drug interventions Not Available Not Available completed NCT00329680
The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of Sepsis No drug interventions treatment 4 completed NCT01973829
The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) No drug interventions supportive_care Not Available completed NCT01371929
Plasma Inducible Nitric Oxide Synthase (iNOS) Assay and Sepsis Study No drug interventions Not Available Not Available terminated NCT02560129
MICU Recovery Clinic No drug interventions Not Available Not Available completed NCT04646629
Effect of Electroacupuncture on Sepsis-induced Intestinal Dysfunction No drug interventions treatment Not Available unknown_status NCT01027429
Simplified Antibiotic Therapy for Sepsis in Young Infants treatment 3 completed NCT04130789
Personalized Swiss Sepsis Study No drug interventions Not Available Not Available unknown_status NCT02568189
Utility of Ultrasound Assessment of the Inferior Vena Cava in Patients With Sepsis and Dehydration No drug interventions diagnostic Not Available terminated NCT03562689
Cognitive Processing in Patients Surviving Delirium. Neuropsychological, EEG and Structural Brain Correlates. No drug interventions Not Available Not Available suspended NCT03179189
Investigation of The Prevalence of Sepsis in Adults in Multicenter Intensive Care Unıts in Turkey No drug interventions Not Available Not Available unknown_status NCT03752489
Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment No drug interventions diagnostic 2 unknown_status NCT03870789
Field Paramedic Application of Sepsis Triage No drug interventions Not Available Not Available unknown_status NCT04414189
Clinical Validation of HostDx Sepsis™ on NanoString; a Prospective Observational Validation Trial No drug interventions Not Available Not Available completed NCT04665089
Erythromycin in Septic Patients: Immunomodulatory Role and Clinical Impact treatment Not Available completed NCT02266589
Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock treatment 3 completed NCT02217592
Causes and Factors Associated With Outcomes in Community-acquired Sepsis and Severe Sepsis in Northeast Thailand No drug interventions Not Available Not Available completed NCT02872792
Early Mobilisation in Intensive Care Unit : Interest of Cyclo-ergometry in Patients With Septic Chock No drug interventions treatment Not Available terminated NCT02188992
Early PREdiction of Severe Sepsis I (ExPRES-Sepsis I) Study No drug interventions Not Available Not Available completed NCT00441792
The Effect of Etomidate on Patient Outcomes After Single Bolus Doses treatment Not Available completed NCT06018792
Molecular Culture for the Diagnosis of Pediatric Sepsis No drug interventions Not Available Not Available recruiting NCT03512392
Role of Active Deresuscitation After Resuscitation-2 No drug interventions treatment Not Available completed NCT01493492
Urinary Proteomics Analysis for Sepsis and Prognosis No drug interventions Not Available Not Available unknown_status NCT03345992
Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System treatment 3 completed NCT06124092
Outcomes of Children After Hospitalization in Intensive Care Unit No drug interventions Not Available Not Available not_yet_recruiting NCT02019992
Investigation of Plasma Mitochondrial DNA Level in Septic Patients No drug interventions Not Available Not Available unknown_status NCT02446392
The Distribution of Plasma Drug Concentrations of Beta-lactam Antibiotics in Intensive Care Unit Patients No drug interventions Not Available Not Available completed NCT00697944
Ambisome® Preemptive Treatment of Multiple Candida Colonization in Sepsis Patients prevention 4 unknown_status NCT02731144
Optimized Caloric-proteic Nutrition in Septic and Septic Shock Patients No drug interventions treatment 4 terminated NCT00384644
Skeletal Muscle Oxygenation in Critically Ill No drug interventions Not Available Not Available unknown_status NCT04441944
TELEmedicine as an Intervention for Sepsis in Emergency Departments No drug interventions Not Available Not Available completed NCT01480544
Improving Maternal and Child Health in India: Evaluating Demand and Supply Side Strategies (IMATCHINE) No drug interventions health_services_research Not Available completed NCT06372444
Mechanisms of Acute Kidney Injury in Severe Infections No drug interventions Not Available Not Available not_yet_recruiting NCT05875740
Correlation of Memory CD8+ T Cells With Sepsis Severity and Mortality: a Single-center, Unblinded, Prospective, Non-interventional, Observational Study No drug interventions Not Available Not Available not_yet_recruiting NCT03115840
Measuring Outcomes of Activity in Intensive Care No drug interventions Not Available Not Available active_not_recruiting NCT02359240
HO-1 and Muscle Mitochondrial Dysfunction in Sepsis No drug interventions Not Available Not Available unknown_status NCT03990467
Observed Pharmacokinetic of Piperacillin/Tazobactam Compared to Amikacin in ICU treatment Not Available unknown_status NCT02578667
Gorbly Compression Device for Use in Image-guided Procedures No drug interventions Not Available Not Available withdrawn NCT03601767
Derivation and Validation of a Prognostic Model for Septic Patients at Hospital Admission No drug interventions Not Available Not Available unknown_status NCT04537767
The Effect of Esmolol on Patients With Sepsis treatment Not Available unknown_status NCT04005001
Machine Learning Sepsis Alert Notification Using Clinical Data No drug interventions other 2 unknown_status NCT01801501
Role of FGF-23 as a Prognosis Biomarker in Intensive Care Patients No drug interventions Not Available Not Available completed NCT04146701
Metabolomics and Microbiomics in Cardiovascular Diseases No drug interventions Not Available Not Available unknown_status NCT02728401
Genotypes and Phenotypes in Pediatric SIRS and Sepsis No drug interventions Not Available Not Available completed NCT05741801
Digital Alerts for Sepsis: a Qualitative Study No drug interventions Not Available Not Available completed NCT06516601
Fulminant Severe CAP - an Observational Study No drug interventions Not Available Not Available recruiting NCT01187004
Extracardiac Complications After Cardiac Surgery No drug interventions Not Available Not Available completed NCT00464204
Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis treatment 3 completed NCT01652404
PROcalcitonin to SHORTen Antibiotics Duration in PEDiatricICU Patients (ProShort-Ped) Trial No drug interventions treatment 3 unknown_status NCT05739604
Serum Free Amino Acid Concentrations in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy (CRRT) No drug interventions Not Available Not Available completed NCT01362504
Pro-adrenomedullin as a Prognostic Marker in Neonatal Sepsis No drug interventions Not Available Not Available completed NCT03341572
The Effect of Positive End Expiratory Pressure on Central Venous Pressure Among Patients With Different Lung Compliance No drug interventions supportive_care Not Available unknown_status NCT00046072
A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis treatment 2 completed NCT03077672
Mitochondrial DNA as a Biomarker of Sepsis Severity No drug interventions Not Available Not Available completed NCT04372472
SQuISH-COVID: A Pilot Study No drug interventions Not Available Not Available unknown_status NCT02860572
Non-interventional Follow-up Versus Fluid Bolus in RESPONSE to Oliguria in the Critically Ill No drug interventions treatment Not Available completed NCT01708772
Serum TNF-a in Comparison to Sequential Organ Failure Assessment (SOFA) Score Monitoring in Critically Ill Patients No drug interventions Not Available Not Available completed NCT06187168
Risk Factors of Post-ERCP Sepsis No drug interventions Not Available Not Available recruiting NCT00448968
The Utility of Ischemia Modified Albumin (IMA) in Sepsis No drug interventions Not Available Not Available completed NCT00247468
Strict Glucose Control of Pediatric Intensive Care Unit (ICU) Patients No drug interventions treatment Not Available withdrawn NCT01603368
Prophylactic Probiotics to Extremely Low Birth Weight Prematures No drug interventions prevention 2 completed NCT00783068
Anti-inflammatory Effects of GTS-21 After LPS treatment Not Available completed NCT05830669
Remote Ischemic Preconditioning in Septic Patients No drug interventions supportive_care Not Available recruiting NCT02661269
Relation Between the Increase of Peripheral Edema by Fluid Therapy and the Decrease in Microcirculatory Vesseldensity No drug interventions Not Available Not Available completed NCT00258869
Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests No drug interventions Not Available Not Available unknown_status NCT04850469
Study of MSC-Exo on the Therapy for Intensively Ill Children No drug interventions Not Available Not Available withdrawn NCT00158769
A Study To Compare The Effects Of The Infusion Of A Sepsis Drug Between Healthy Adults And Adults With Damaged Livers treatment 1 completed NCT05305469
Early Identification and Prognosis Prediction of Sepsis Through Multiomics No drug interventions Not Available Not Available recruiting NCT05111769
Preliminary Study on the Clinical Effect of Recombinant Human Brain Natriuretic Peptide on Sepsis Complicated With Heart Failure treatment Not Available unknown_status NCT02210169
RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates treatment Not Available completed NCT05808946
Alpha-Lipoic Acid in Patients With Sepsis treatment 2 / 3 recruiting NCT05118646
Comparison of Microcirculation Indexes and Hemodynamic Indexes to Guide Resuscitation in Patients With Septic Shock No drug interventions other Not Available unknown_status NCT04913246
Triage Score VS Quick-Sofa Score in Septic Patients in the Emergency Department No drug interventions Not Available Not Available completed NCT01229046
Pharmacokinetics and Safety of Ticarcillin-clavulanate in Infants Not Available 1 withdrawn NCT01069146
Mild Therapeutic Hypothermia During Severe Sepsis No drug interventions treatment Not Available completed NCT01791712
Efficacy of Online Hemodiafiltrationlysis in Cytokine Removal No drug interventions treatment Not Available completed NCT06326112
Role of Active Deresuscitation After Resuscitation: treatment 2 not_yet_recruiting NCT01365312
Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates prevention Not Available terminated NCT05310812
Evaluation of Candidate Biomarkers to Predict Disease Severity and Acute Kidney Injury in Sepsis Patients No drug interventions Not Available Not Available completed NCT02328612
Randomized, Parallel Group, Placebo Control, Unicentric, Interventional Study to Assess the Effect of Expanded Human Allogeneic Adipose-derived Mesenchymal Adult Stem Cells on the Human Response to Lipopolysaccharyde in Human Volunteers No drug interventions treatment 1 completed NCT05208112
Intravenously Administered M6229 in Critically Ill Sepsis Patients No drug interventions treatment 1 completed NCT04141410
Global Longitudinal Strain Assessment in Cardiogenic Shock During Sepsis Not Available Not Available unknown_status NCT03133910
Pharmacokinetics and Pharmacodynamics of Ceftazidime in Pediatric ICU Patients No drug interventions Not Available Not Available unknown_status NCT00159510
Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome treatment 1 terminated NCT03716310
Platelet Reactivity in Septic Shock No drug interventions Not Available Not Available completed NCT03010410
Platelet Immune Responses in Aging and Influenza and Sepsis (INVACS) No drug interventions Not Available Not Available unknown_status NCT01286610
Applicability and Safety of Vibration Therapy in Intensive Care Unit (ICU) Patients No drug interventions other Not Available completed NCT00628381
L-citrulline Supplementation During Sepsis No drug interventions treatment 3 unknown_status NCT02398981
Implementation of a Web Based Real Time Clinical Decision Support Tool. No drug interventions supportive_care Not Available completed NCT00368381
Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis treatment 4 withdrawn NCT00716781
Management of Infants Born to Group B Streptococcus Positive Mothers. No drug interventions Not Available Not Available completed NCT03217981
Sepse: Critical Analysis of New Sepse Definitions and Retrospective Evaluation of Sepse Protocol at a Tertiary Hospital in Brazil No drug interventions Not Available Not Available unknown_status NCT01817881
Investigation of the Accuracy of Temporal Artery Thermometers No drug interventions Not Available Not Available completed NCT04794595
Clinical Features and Outcomes of CBP Versus Non-CBP in Septic Children No drug interventions Not Available Not Available recruiting NCT03884595
Early Identification of Sepsis in Children No drug interventions Not Available Not Available unknown_status NCT02883595
Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis treatment 4 completed NCT05059795
Volume Resuscitation in Cirrhosis With Sepsis Induced Hypotension Not Available Not Available recruiting NCT02238795
Sepsis-Associated Purpura Fulminans International Registry - Europe No drug interventions Not Available Not Available completed NCT02714595
Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens treatment 3 completed NCT02871895
Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis No drug interventions Not Available Not Available unknown_status NCT02052895
Utility of Presepsin in Distinguishing Between Sepsis and SIRS No drug interventions Not Available Not Available completed NCT06265714
The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia No drug interventions Not Available Not Available completed NCT03438214
Effect of Intermittent Infusion Versus Continuous Infusion of Vancomycin on Kidney Failure in Critically Ill Patients treatment 4 unknown_status NCT03685214
Comparison of Balanced Crystalloids and Normal Saline in Septic Patients treatment Not Available unknown_status NCT02207114
Using Biomarkers to Optimize Antibiotic Strategies in Sepsis No drug interventions diagnostic Not Available completed NCT00851214
Use of Non Invasive Hemodynamic Cardiovascular Monitoring to Evaluate Emergency Department Patients No drug interventions Not Available Not Available completed NCT01388114
Clinical Evaluation of e- Ab Sensor - Based Real-time Diagnosis of Serum Procalcitonin Level No drug interventions diagnostic Not Available completed NCT05694455
Micro and Macro Circulation in Sepsis No drug interventions basic_science Not Available recruiting NCT03139955
Bodytrak® Feasibility Study No drug interventions Not Available Not Available unknown_status NCT02135055
Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status treatment 4 unknown_status NCT04803955
Efficacy and Safety of Kukoamine B Mesilate in Sepsis Patients No drug interventions treatment 2 recruiting NCT03717350
suPAR to Guide Antibiotics in Emergency Department treatment 2 / 3 unknown_status NCT03388450
Omega-3 Fatty Acid for Critically Ill Patients. No drug interventions other Not Available completed NCT00519350
Towards a High-fat Feeding Intervention Study: Identification of Markers for Inflammation and Organ Damage No drug interventions Not Available Not Available completed NCT03661450
Evaluation of CDSS in Detection of SIRS and Sepsis in Pediatric Patients No drug interventions Not Available Not Available completed NCT04356950
Analysis of the Coagulopathy Developed by COVID-19 Infected Patients No drug interventions Not Available Not Available completed NCT02366650
Help in the Emergency Room to Detect Organ Dysfunction No drug interventions Not Available Not Available unknown_status NCT01080950
Vitamin D Zinc Fever No drug interventions Not Available Not Available unknown_status NCT05428423
Reliability of PVI Changes During Tidal Volume Challenge in ICU Patients No drug interventions Not Available Not Available recruiting NCT00357123
Effect of Rosuvastatin in Abdominal Sepsis treatment 2 unknown_status NCT02467023
Project 4B: Lower Extremity Strength Training in ICU Patients treatment Not Available completed NCT00016523
Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure treatment 3 terminated NCT03044223
Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis No drug interventions Not Available Not Available recruiting NCT04904523
Blood Markers for Identifying & Investigating Infection With COVID19 & Sepsis in Children. No drug interventions Not Available Not Available unknown_status NCT05826223
Novel Sepsis Sub-phenotypes Based on Trajectories of Vital Signs No drug interventions Not Available Not Available not_yet_recruiting NCT05882708
Effect of Heart Rate Control With Ivabradine on Hemodynamic in Patients With Sepsis treatment 4 recruiting NCT04291508
Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery treatment 2 completed NCT01705808
Administration of Protein C Concentrates in Adult Critically Ill Septic Patients treatment 3 terminated NCT00100308
Unfractioned Heparin for Treatment of Sepsis treatment 3 completed NCT06072508
Prognostic Interest of Vasorin in Septic Shock No drug interventions other Not Available recruiting NCT05495438
Impact and Safety of AI in Decision Making in the ICU: a Simulation Experiment No drug interventions Not Available Not Available completed NCT00001338
A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer No drug interventions treatment 3 completed NCT04542538
The Impact of Premorbid Illnesses on the Risk of ICU Admission and Short-term Outcome No drug interventions Not Available Not Available completed NCT03789838
Effect of Sepsis Response Team in the Emergency Department No drug interventions Not Available Not Available completed NCT04032938
Multi-omics Study on Gut Microbiota in Critical Ill Patients After Cardiopulmonary Bypass No drug interventions Not Available Not Available unknown_status NCT02452138
Endotoxin Activity Assay and Microcirculation in Severe Sepsis No drug interventions Not Available Not Available unknown_status NCT05979038
Clinical Evaluation of the Effect of Metformin in Sepsis treatment 3 recruiting NCT02899143
Short-course Antimicrobial Therapy in Sepsis No drug interventions treatment 2 unknown_status NCT04032743
Risk Factors and Treatment Outcome of Oncology Children Hospitalized in the Intensive Care Unit Due to Sepsis No drug interventions Not Available Not Available unknown_status NCT04214743
Ocular Microvascular Changes in Patients With Sepsis No drug interventions Not Available Not Available completed NCT02344043
Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness No drug interventions Not Available Not Available completed NCT03727243
Molecular Diagnosis and Risk Stratification of Sepsis in India No drug interventions Not Available Not Available unknown_status NCT04934943
"Mini Fluid Challenge Assessment: a Comparison Among Three Hemodynamic Tools" No drug interventions Not Available Not Available unknown_status NCT01504243
Association Between cd163 Gene Polymorphisms and Sepsis Among Chinese Han Population No drug interventions Not Available Not Available unknown_status NCT06021743
The Role of Immune Semaphorins in Steatotic Liver Disease and Sepsis No drug interventions Not Available Not Available recruiting NCT04044703
Improving Dosing of Vancomycin in Young Infants With Infections treatment 4 completed NCT03048903
The Effect of Rhubarb on Sepsis and Post-traumatic Gastrointestinal Function Failure No drug interventions treatment 2 unknown_status NCT00001303
Effects of Endotoxin in Normal Human Volunteers treatment 1 completed NCT01223690
Clarithromycin as Immunomodulator for the Management of Sepsis treatment 3 completed NCT02523690
Evaluating Muscle Weakness Improvement With Lorcaserin in ICU treatment 1 / 2 terminated NCT02085590
Effects of BCG on Immune Response treatment 2 / 3 completed NCT03494790
Markers of Inflammation and Metabolism in the ER No drug interventions Not Available Not Available completed NCT04313790
Assessment of the Anti-inflammatory Effect of Heparin Infusion Versus Subcutaneous Injection in Septic Patients prevention 2 completed NCT00862290
Circulating microRNAs as Biomarkers of Sepsis No drug interventions Not Available Not Available completed NCT00495690
Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Disease supportive_care 3 completed NCT05296590
Monocyte Distribution Width (MDW) in the General Population of Emergency Department Patients With and Without Bacteremia No drug interventions Not Available Not Available active_not_recruiting NCT01964690
Lactate Use as Triage Tool in Sepsis : Veinous, Capillary or Arterial? No drug interventions Not Available Not Available completed NCT04910464
Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis treatment 3 recruiting NCT05663164
Effect of Thiamine on Serum Glucagon And Reactive Oxygen Species (ROS) treatment Not Available completed NCT01889264
Methionine Metabolism in Enterally Fed Pediatric Sepsis No drug interventions Not Available Not Available completed NCT05625464
Effect of Automated Real-time Feedback on Early Sepsis Care No drug interventions prevention Not Available completed NCT02926664
Delta qSOFA for Risk Stratification in Emergency Infected Patients No drug interventions Not Available Not Available completed NCT04147221
Imipenem-Relebactam Pharmacokinetics in Augmented Renal Clearance other 1 completed NCT01449721
Preemptive Resuscitation for Eradication of Septic Shock No drug interventions treatment Not Available completed NCT05076721
Effectiveness of Simulation Based Training in Implementing One Hour Bundle Sepsis No drug interventions other Not Available completed NCT04092621
Rapid Atrial Fibrillation Treatment Strategy treatment 4 unknown_status NCT05691621
Galectin-3 in Septic and Non-septic Acute Kidney Injury No drug interventions Not Available Not Available recruiting NCT02747121
Effects of External Inspection on Sepsis Detection and Treatment No drug interventions health_services_research Not Available completed NCT01146821
Fish OIL Optimal dosE Determination Study No drug interventions treatment 2 terminated NCT01309321
Perinatal Handwashing Intervention in Bangladesh No drug interventions prevention Not Available completed NCT04261621
Early Identification of SEPsis SIGNs in Emergency Department No drug interventions Not Available Not Available completed NCT04285021
Prediction of Disease Severity in Young Children Presenting With Acute Febrile Illness in Resource-limited Settings No drug interventions Not Available Not Available completed NCT00837421
The Ohio State University Sepsis Registry No drug interventions Not Available Not Available terminated NCT03025802
Fast Assay for Pathogen Identification and Characterization - Prospective Study No drug interventions Not Available Not Available completed NCT05703802
Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia. No drug interventions Not Available Not Available completed NCT02852902
Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Multinational Study. No drug interventions Not Available Not Available completed NCT04028102
Ultrasound Optimization of Initial Fluid Challenge in Sepsis No drug interventions Not Available Not Available unknown_status NCT05636202
The Role of NLR in the Diagnosis and Prognosis of Sepsis No drug interventions Not Available Not Available completed NCT02953002
The Correlation Between The New Sepsis Scores - SOFA, Quick SOFA and Calibrated Automated Thrombogram Values No drug interventions Not Available Not Available completed NCT00901602
Lebanese Interhospital Pneumococcal Surveillance Program No drug interventions Not Available Not Available recruiting NCT05787184
Sepsis Early EvaluatioN Through Rapid Ultrasound and veNous Gas Analysis No drug interventions Not Available Not Available recruiting NCT00735384
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies No drug interventions Not Available Not Available completed NCT03015584
Systems Biology Approach to Cognitive Impairment After SepsiS No drug interventions Not Available Not Available completed NCT00527384
Biomarker Analysis of Stress No drug interventions Not Available Not Available completed NCT05909384
Management of Sepsis in Resource Limited Settings Using a Delphi Method. No drug interventions Not Available Not Available completed NCT03258684
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock treatment Not Available completed NCT03348579
Hospital-acquired Pneumonia in Intensive Care Unit No drug interventions Not Available Not Available completed NCT05060679
Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction No drug interventions Not Available Not Available completed NCT05971979
Therapeutic Drug Monitoring - Targeting IMproved Effectiveness No drug interventions Not Available Not Available recruiting NCT03201679
The Association Between Preoperative Sepsis and the Mortality After Hip Fracture Surgery No drug interventions Not Available Not Available completed NCT04080479
Bolus Versus Continuous Enteral Tube Feeding No drug interventions supportive_care Not Available completed NCT05172479
Prognostic Accuracy of qSOFA, SIRS, and EWSs for In-hospital Mortality in Emergency Department No drug interventions Not Available Not Available completed NCT02159079
A Randomized Controlled Trial of a Conservative Fluid Balance Strategy for Patients With Sepsis and Cardiopulmonary Dysfunction (BALANCE Study) No drug interventions treatment Not Available completed NCT04873479
Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery treatment Not Available unknown_status NCT04203979
Sepsis: From Syndrome to Personalized Care No drug interventions Not Available Not Available recruiting NCT01151579
Effect of Nebulized Bronchodilators on Heart Rate supportive_care 4 completed NCT06289179
Thyroid and Cortisol Hormone Response to Sepsis No drug interventions Not Available Not Available not_yet_recruiting NCT05968287
Can Measurement of Neutrophil-derived ROS Production be a Novel Biomarker of Sepsis? No drug interventions Not Available Not Available completed NCT03654287
Exploring and Establishment of Combined Extracorporeal Life Support(CELS) in Critically Ill Children No drug interventions Not Available Not Available withdrawn NCT06122987
Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock treatment 4 recruiting NCT02170233
SHOCK US STUDY: Fluid Responsiveness in Sepsis Measured by Ultrasonography No drug interventions Not Available Not Available completed NCT04740333
Prognostic Impact of Admission Glucose Level in Septic Patients Admitted to the Intensive Care Unit No drug interventions Not Available Not Available completed NCT05998733
The Impact of Coagulation Disorders on the Diagnosis and Prognosis of Sepsis No drug interventions Not Available Not Available recruiting NCT05634733
Change in MAPSE During Treatment of Sepsis No drug interventions Not Available Not Available recruiting NCT01905033
Molecular Diagnosis and Risk Stratification of Sepsis No drug interventions Not Available Not Available unknown_status NCT05065333
Implementation Trial of Predictive Modeling to Enhance Diagnosis and Improve Treatment in Pediatric Septic Shock No drug interventions diagnostic Not Available completed NCT05283733
Open to Laparoscopic Reverse Conversion of Perforated Appendicitis No drug interventions treatment Not Available completed NCT05978154
Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department No drug interventions Not Available Not Available recruiting NCT06082154
A Prognostic Model Based on POCUS at ICU Admission in Critically Ill Patients With Sepsis No drug interventions Not Available Not Available completed NCT01976754
Safety Study of Dexmedetomidine in Septic Patients supportive_care Not Available completed NCT01406951
Diagnostic Value of sTREM-1 and PCT Level as Well as CPIS Score for Ventilator-Associated Pneumonia Among ICU Sepsis Patients No drug interventions Not Available Not Available completed NCT04448951
Immune Homeostasis in Sepsis and Septic Shock No drug interventions Not Available Not Available recruiting NCT00428051
Colombia Epidemiologic Surveillance Study No drug interventions Not Available Not Available terminated NCT05897151
Continuous Spinal Anesthesia Versus General Anesthesia in Sepsis No drug interventions treatment 4 recruiting NCT03919851
Physician Administered Antibiotics in a Prehospital Setting No drug interventions Not Available Not Available completed NCT03395951
Mean Systemic Filling Pressure Continuous Diuretics Critical Care Patients No drug interventions Not Available Not Available completed NCT02114853
Oxidative Monitoring in ICU Patients. No drug interventions Not Available Not Available unknown_status NCT01438853
Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome No drug interventions treatment 1 completed NCT05402553
The Efficacy of Adjunctive Use of Ondansetron in Patients With Sepsis and Septic Shock treatment 1 / 2 recruiting NCT04033653
Long-term Quality of Life Among Survivors of Sepsis in China Assessed by EQ-5D No drug interventions Not Available Not Available completed NCT01891253
Inert Gas Rebreathing in Ventilated Patients No drug interventions Not Available Not Available unknown_status NCT03509753
Prebiotic Fiber to Prevent Pathogen Colonization in the ICU No drug interventions prevention Not Available completed NCT03277677
The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients No drug interventions treatment 3 completed NCT04755777
Provider Perspectives on Beta-lactam Therapeutic Drug Monitoring Programs in the Critically Ill No drug interventions Not Available Not Available completed NCT03935477
Surrogate of Adequate Perfusion: Bladder Tissue Oxygen Monitoring No drug interventions Not Available Not Available unknown_status NCT01201577
Biological Modulation of Bacterial QSSMs, Innate and Adaptive Immunity by Antibiotics, Probiotics and Prebiotics in Healthy Individuals basic_science 1 completed NCT02277977
Evaluation of Impaired Microcirculation During Septic Shock With Contrast Enhanced Ultrasound No drug interventions diagnostic Not Available withdrawn NCT00732277
Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study treatment 2 completed NCT03592277
Vitamin C & Thiamine to Treat Sepsis and Septic Shock treatment 2 completed NCT00049777
A Trial of Heparin in Patients With Severe Sepsis Who Are Undergoing Treatment With Drotrecogin Alfa (Activated) treatment 4 completed NCT01135277
Immune Suppression and Ventilator Associated Pneumonias No drug interventions Not Available Not Available completed NCT01379547
Procalcitonin to Shorten Antibiotics Duration in ICU Patients No drug interventions treatment 3 unknown_status NCT03489447
Mortality of Sepsis in Swedish Intensive Care Units 2008-2016 No drug interventions Not Available Not Available completed NCT03937245
Epidemiology and Determinants of Outcomes of Hospital Acquired Blood Stream Infections in the Intensive Care No drug interventions Not Available Not Available completed NCT04624945
DetectIon of Severe Sepsis In PATients With Neurological haemorrhagE (The DISSIPATE Study) No drug interventions Not Available Not Available recruiting NCT01203345
Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection prevention 2 / 3 completed NCT04530045
Target Attainment of TDM-guided Infusion of Piperacillin/Tazobactam and Cefepim in Critically Ill Patients No drug interventions Not Available Not Available completed NCT03005145
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness No drug interventions treatment Not Available completed NCT01928745
Experimental Determination of Atot en Ka in the Critically Ill No drug interventions Not Available Not Available completed NCT05072145
Evaluating Tele-Emergency Care in Costs and Outcomes for Rural Sepsis Patients No drug interventions Not Available Not Available completed NCT02426645
Microcirculatory Alteration and Biomarkers: New Approach for Early Assessment of Septic Multi-organ Dysfunction No drug interventions Not Available Not Available unknown_status NCT01161745
PD-1/PD-L1 Pathway Study on Septic Patients No drug interventions Not Available Not Available completed NCT00406198
Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis No drug interventions supportive_care 4 completed NCT04618198
Early Empiric Anti-Mycobacterium Tuberculosis Therapy for Sepsis in Sub-Saharan Africa No drug interventions treatment 3 recruiting NCT06302998
Dexmedetomidine and Vasopressin in Septic Shock treatment 2 not_yet_recruiting NCT06256198
Role of PCO2 Gap as Predictor of Clinical Outcome in ICU Septic Patients No drug interventions Not Available Not Available not_yet_recruiting NCT05623098
Effects of Dietary Fiber on Bone Metabolism No drug interventions Not Available Not Available active_not_recruiting NCT00791505
Antibiotic/COPD in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Requiring Mechanical Ventilation treatment 3 completed NCT04774705
Effectiveness of Non-invasive Vagus Nerve Stimulation as an Adjuvant Treatment in Patients With Sepsis in Intensive Care. No drug interventions other Not Available recruiting NCT04903405
Immune Function Monitoring and Immunotherapy in Sepsis No drug interventions Not Available Not Available unknown_status NCT02699905
Neutrophil FFA2/GPR43 Receptor Expression in Patients With the Diagnosis of Sepsis No drug interventions Not Available Not Available withdrawn NCT01713205
Prediction Study of Complications After Severe Trauma No drug interventions Not Available Not Available unknown_status NCT02108405
The Value of Memory B Cells Marker (CD27) and Howell Jelly Bodies Detrection in Critically Ill Patients No drug interventions Not Available Not Available completed NCT06478797
Early Resuscitation in Paediatric Sepsis Using Inotropes treatment 2 not_yet_recruiting NCT01647997
Lactate Metabolism After an Endotoxin Challenge in Healthy Humans No drug interventions basic_science Not Available completed NCT02474797
Ultrasound Diaphragmatic Thickening to Monitor Its Dysfunction in Patients With Sepsis No drug interventions screening Not Available completed NCT02039297
Patient Centered Cloud-based Electronic System: Ambient Warning and Response Evaluation (ProCCESs AWARE) No drug interventions supportive_care Not Available completed NCT02934997
The Role of Dysfunctional HDL in Sepsis No drug interventions Not Available Not Available completed NCT02399397
Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics treatment 4 completed NCT01027897
Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients treatment 4 completed NCT03249597
Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance No drug interventions Not Available Not Available completed NCT00926497
Procalcitonin-Guided Decision Making to Shorten Antibiotic Therapy in Suspected Neonatal Early-Onset Sepsis No drug interventions treatment Not Available completed NCT01501097
The Impact of Continuous Renal Replacement Therapy on the Outcomes of Burn Patients With Early Phase of Sepsis No drug interventions treatment Not Available unknown_status NCT00883597
Sidestream Dark-Field (SDF) Imaging of the Intestinal Microcirculation No drug interventions Not Available Not Available completed NCT05267483
Evaluation of Usage Patterns and Outcomes in Patients Receiving Ceftolozane/Tazobactan (C/T) in Brazilian Hospitals No drug interventions Not Available Not Available unknown_status NCT01670383
Repository for Sepsis and Postresuscitation Samples No drug interventions Not Available Not Available recruiting NCT00185783
Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis Not Available Not Available completed NCT05909683
Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the MODIFY Trial) No drug interventions diagnostic 3 recruiting NCT05259683
Febrile Infant Diagnostic Assessment and Outcome Study No drug interventions Not Available Not Available completed NCT05557461
Assessment of Fluid Responsiveness in Septic Shock Patients, Can End-tidal co2 Measurement Help? No drug interventions Not Available Not Available recruiting NCT00395161
The CRISIS Prevention Study prevention 3 terminated NCT02654561
Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation treatment 3 recruiting NCT06242561
Quantification of Dilutional Anemia in the Initial Phase of Sepsis Management: Preliminary Retrospective Study No drug interventions Not Available Not Available completed NCT03256461
Lactate Clearance Goal-directed Therapy in Sepsis No drug interventions treatment Not Available unknown_status NCT03847961
Efficacy and Safety Study of CA330 Hemoadsorption Device on IL-6 Removal in Septic Patients No drug interventions treatment Not Available unknown_status NCT01725061
Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis No drug interventions Not Available Not Available completed NCT00472628
Multi-marker INDex for the Risk Assessment of Sepsis in the Emergency departmenT (MINDSET) No drug interventions Not Available Not Available withdrawn NCT06197828
Novel Biomarkers for Early Renal Injury in Children With Sepsis No drug interventions Not Available Not Available active_not_recruiting NCT05036928
Study of MDW Levels Predicting the Development of Sepsis in Hospitalized HIV-infected Patients and Correlation With Prognosis No drug interventions Not Available Not Available unknown_status NCT01988428
Prehospital Antibiotics Against Sepsis Trial treatment Not Available completed NCT05229328
Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Sepsis No drug interventions Not Available Not Available recruiting NCT03245528
Expanded Access for LJPC-501 No drug interventions Not Available Not Available approved_for_marketing NCT04974411
Establishment of Early Diagnosis and Monitoring Model for Sepsis Patients No drug interventions Not Available Not Available unknown_status NCT02971111
Thromboelastometry in Assessment of Sepsis Coagulopathy No drug interventions Not Available Not Available completed NCT01374711
The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia No drug interventions treatment Not Available completed NCT05911711
Identification and Clinical Efficacy Analysis of Biomarkers in Sepsis Patients No drug interventions Not Available Not Available recruiting NCT01465711
The Value of PSP in Predicting Outcome in ICU Surgical Peritonitis Patients No drug interventions Not Available Not Available completed NCT06556511
Efficacy Of Zinc Towards The Outcome on Children With Sepsis other Not Available completed NCT02020811
Safety and Efficacy of Immages System in Patients Recieving IV Therapy No drug interventions Not Available Not Available unknown_status NCT03847493
Analysis of Sublingual Glycocalyx Damage at ICU Admission to Predict Risk of Death No drug interventions Not Available Not Available unknown_status NCT04767893
Diagnostic and Prognostic Biomarkers of Sepsis No drug interventions Not Available Not Available completed NCT03158493
Assessment of qSOFA in the Latin America Sepsis Institute Database No drug interventions Not Available Not Available completed NCT00537693
Cytokine Removal by CRRT in Pediatric Sepsis No drug interventions treatment Not Available completed NCT03634293
Treatment of Severe Infection With Antihyperlipidemia Drug treatment 2 / 3 unknown_status NCT03991793
Granzyme A in Patients With E. Coli Bacteremic Urinary Tract Infections No drug interventions Not Available Not Available unknown_status NCT03440593
Indirect Calorimetry Usage and Effect in Ventilator-free Days and Muscle Thickness in Septic Ventilated Patients No drug interventions treatment Not Available completed NCT06476171
Validation of Hematological Indices No drug interventions diagnostic Not Available recruiting NCT02611271
Elimination of Antibiotics During Renal Replacement Therapy and Cytosorb Adsorptive Therapy No drug interventions Not Available Not Available unknown_status NCT03464071
Biomarkers of Lung Injury in Hyperinflation in the Mechanical Ventilator Versus Manual Hyperinflation No drug interventions diagnostic Not Available unknown_status NCT02704871
The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRS No drug interventions Not Available Not Available terminated NCT02308371
PPV to Guide Fluid Management in the PICU No drug interventions diagnostic Not Available completed NCT02444871
IgM-enriched Immunoglobulin Attenuates Systemic Endotoxin Activity in Early Severe Sepsis No drug interventions Not Available Not Available completed NCT03178578
A Prospective Observational Study of the Expectations and Physiological Effects of Fluid Bolus Therapy No drug interventions Not Available Not Available unknown_status NCT03333278
The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial treatment 2 completed NCT02545478
Biomarkers in Infection No drug interventions Not Available Not Available unknown_status NCT01505478
Comparing an Automated to a Conventional Sepsis Clinical Prediction Rule No drug interventions Not Available Not Available withdrawn NCT01410578
The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO No drug interventions Not Available Not Available completed NCT00793078
Arterial Blood Pressure-complexity in Septic Patients No drug interventions Not Available Not Available suspended NCT06368388
Bacteriophage Therapy for Difficult-to-treat Infections: the Implementation of a Multidisciplinary Phage Task Force No drug interventions Not Available Not Available recruiting NCT01203488
Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants prevention 1 / 2 completed NCT05048888
Symphony IL-6 Reference Range Study No drug interventions Not Available Not Available recruiting NCT01312688
Early Goal-directed Therapy and Myocardial Dysfunction No drug interventions treatment Not Available unknown_status NCT00005888
Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants No drug interventions treatment Not Available completed NCT01904188
Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate? No drug interventions Not Available Not Available recruiting NCT00335907
Protocol-driven Hemodynamic Support for Patients With Septic Shock No drug interventions treatment Not Available unknown_status NCT03960307
Glycocalyx and Microcirculation in Sepsis No drug interventions Not Available Not Available completed NCT03620409
Identification of Cardiovascular and Molecular Prognostic Factors for the Mid- and Long-term Outcome of Sepsis No drug interventions Not Available Not Available completed NCT06307509
Adiposity and Immunometabolism in Sepsis No drug interventions Not Available Not Available not_yet_recruiting NCT05691309
Optimizing Vancomycin Therapy in Children No drug interventions Not Available Not Available completed NCT05127109
The PASTDUe Nutrition Ecosystem Project (PASTDUe) No drug interventions treatment 4 recruiting NCT03474809
Early Diagnostic of Sepsis and Potential Impact on Antibiotic Management Based on Serial.Pancreatic Stone Protein (PSP) Measured Using the AbioScope. No drug interventions Not Available Not Available completed NCT04393909
Improving Safety of Diagnosis and Therapy in the Inpatient Setting No drug interventions prevention Not Available completed NCT01865656
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka No drug interventions prevention Not Available completed NCT02914756
HMGB1 in ICU-survivors No drug interventions Not Available Not Available completed NCT03231956
CLEAR Sepsis Clinical Study No drug interventions Not Available Not Available unknown_status NCT03715556
Control Versus Liberal Cardiac Frequency in Patients in Sepse With Atrial Fibrillation of High Ventricular Response treatment 3 unknown_status NCT04304456
Epidemiology and Determinants of Outcomes of Hospital Acquired Blood Stream Infections in the Intensive Care in Turkey No drug interventions Not Available Not Available unknown_status NCT04796285
A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor No drug interventions diagnostic Not Available active_not_recruiting NCT01862185
The Effect of Semi-quantitative Procalcitonin Assay to The Adequacy of Empirical Antibiotics and Mortality in Septic Patients No drug interventions diagnostic 3 completed NCT01234285
Safety of Heparin in Patients With Septic Shock treatment 2 withdrawn NCT00930085
Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients No drug interventions Not Available Not Available completed NCT03764085
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis. treatment 4 completed NCT03179215
Dynamic Arterial Elastance as a Predictor of Arterial Blood Pressure Response to Fluid Administration in Septic Patients No drug interventions Not Available Not Available completed NCT06087315
Evaluation of a Multi-country Medical Oxygen Program No drug interventions Not Available Not Available recruiting NCT03796715
Red Cell Distribution Width Versus Presepsin (Soluble CD14) as a Prognostic Marker in Critically-ill Sepsis Patients No drug interventions Not Available Not Available completed NCT03760315
mNGS vs Culture Critically Ill Patients No drug interventions Not Available Not Available unknown_status NCT04197115
Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis treatment 3 completed NCT04178915
Study of Leukocyte Immunophenotype and the Lipid Transport System as Predictive Biomarkers of Severe Bacterial Infections No drug interventions Not Available Not Available enrolling_by_invitation NCT04239937
Insulin Resistance in Stress-metabolic Medical Patients No drug interventions Not Available Not Available unknown_status NCT04999137
Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa treatment 2 unknown_status NCT04717037
Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS) prevention 2 / 3 unknown_status NCT05640037
Urine Interleukin-37 as a Biomarker of Mortality Risk in Patients With Sepsis No drug interventions Not Available Not Available completed NCT03748537
Mitochondrial Function in Septic Patients basic_science Not Available completed NCT05110937
Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis No drug interventions Not Available Not Available recruiting NCT00844337
Simplified Antibiotic Regimens for Outpatient Treatment of Suspected Sepsis in Neonates and Young Infants in Bangladesh treatment Not Available completed NCT04876937
Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients prevention Not Available unknown_status NCT02213237
The Application of SERS and Metabolomics in Sepsis No drug interventions Not Available Not Available unknown_status NCT02330432
Mycobacterium w in Patients With Severe Sepsis No drug interventions treatment 2 / 3 completed NCT05293132
Effect of Montelukast Versus Co Enzyme in Sepsis treatment 2 / 3 completed NCT03126032
Early Detection of Glycocalyx Damage in Emergency Room Patients No drug interventions Not Available Not Available completed NCT01636232
Vitamin D and Critically Ill Patients No drug interventions Not Available Not Available completed NCT03475732
Pharmacokinetics of XueBiJing in Patients With Sepsis No drug interventions treatment Not Available completed NCT04149132
Pulse Photoplethysmography as an Early Tool for the Diagnosis of Sepsis No drug interventions Not Available Not Available completed NCT00854932
Neonatal Procalcitonin Intervention Study No drug interventions treatment Not Available unknown_status NCT04426032
Predictive Value of Doppler RSI for Prediction of AKI in Septic Patients in ICU No drug interventions Not Available Not Available completed NCT03224052
Empirical ANtibiotic THErapy in Adults Hospitalised With Malaria No drug interventions Not Available Not Available completed NCT01045252
Study of Hemodynamics of Neonates by Echocardiography and USCOM No drug interventions Not Available Not Available unknown_status NCT05730452
Smart Discharges to Improve Post-discharge Health Outcomes in Children No drug interventions treatment Not Available recruiting NCT01472952
System-level Monitoring of Immune Activation Concerning Susceptibility to Sepsis in Trauma Patients No drug interventions Not Available Not Available withdrawn NCT04227652
Control of Fever in Septic Patients treatment Not Available completed NCT06258252
Effect of Metabolic Dysfunction in Branched-chain Amino Acids on Cardiac Function in Patients With Sepsis No drug interventions Not Available Not Available not_yet_recruiting NCT00271752
The Procalcitonin and Survival Study No drug interventions treatment Not Available completed NCT00318552
Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients. treatment 4 completed NCT04015752
Sepsis in ICU:Causes and Outcomes of Sepsis in Diabetics Versus Non Diabetics in Assiut University Hospital No drug interventions Not Available Not Available unknown_status NCT02764359
Study of Obese Patients Comparing Two Vancomycin Loading Dose Regimens treatment Not Available unknown_status NCT04216459
Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis prevention Not Available completed NCT02157259
An Observational Study of the Causes, Management, and Outcomes of Community-acquired Sepsis and Severe Sepsis in Southeast Asia No drug interventions Not Available Not Available completed NCT03565159
Pneumococcal Vaccination to Accelerate Immune Recovery in Sepsis Survivors prevention 4 completed NCT03996759
Early Prediction of Sepsis by Using Metabolomics No drug interventions Not Available Not Available unknown_status NCT05139459
Sepsis Characterization in Kilimanjaro No drug interventions Not Available Not Available completed NCT06184659
Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis treatment 4 not_yet_recruiting NCT03799159
Renal Arterial Resistive Index Versus Novel Biomarkers for Early Prediction of Sepsis Associated-acute Kidney Injury No drug interventions Not Available Not Available completed NCT01784159
ASpirin for Patients With SEPsis and SeptIc Shock treatment 2 terminated NCT05374759
NGAL and Renal Resistive Index in the Diagnosis and Prognosis of Sepsis-associated AKI No drug interventions Not Available Not Available completed NCT02694159
Physician Judgment and Machine Predictions No drug interventions Not Available Not Available completed NCT05671159
COMPArative Study of the Consequence on innaTe Immune Response du to Bacterial or Viral Infection in Patients Admitted to Intensive Care Unit No drug interventions basic_science Not Available recruiting NCT01900275
Urinary Heparanase Activity as a Predictor of Acute Kidney Injury in Critically Ill Adults No drug interventions Not Available Not Available completed NCT06061575
Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients treatment 4 recruiting NCT02288975
Adsorbtion of Cytokines Early in Septic Shock: the ACESS Study No drug interventions Not Available Not Available completed NCT01494675
Procalcitonin as a Tool to Shorten Antibiotic Therapy in the ICU No drug interventions Not Available Not Available completed NCT05605275
CRP and PCT as Predictors of Sepsis Cause No drug interventions Not Available Not Available completed NCT01167075
A Study in Critically Ill Patients Investigating Tolerability and Efficacy of Low-volume Pharmaconutrition (Intestamin) No drug interventions supportive_care Not Available completed NCT04029675
High Dose of Vitamin C on Mechanically Ventilated Septic Patients in Intensive Care Unit No drug interventions other Not Available completed NCT05969275
Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock treatment 2 recruiting NCT02820675
Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions No drug interventions health_services_research Not Available completed NCT01453270
Emergency Department Management of Sepsis Patients: A Goal-Oriented Non-Invasive Sepsis Trial No drug interventions treatment Not Available completed NCT02361970
Study on the Role of Gamma Delta T Cells in Sepsis Immunosuppression and Its Molecular Mechanism No drug interventions Not Available Not Available completed NCT05349370
Lactate Kinetics in Septic Shock No drug interventions basic_science Not Available recruiting NCT02888470
Administration of Amino-glycoside in ICU Patients : Clinical Practices in 2013 No drug interventions Not Available Not Available completed NCT00284570
Pro-Calcitonin Levels Following Pediatric Cardiac Surgery No drug interventions Not Available Not Available completed NCT00136370
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn prevention 3 unknown_status NCT02971670
Amendment of rTSST-1 Variant Vaccine Phase 1 Clinical Trial No drug interventions treatment 1 completed NCT02930070
qSOFA in General Wards: the Accuracy in Diagnosis of Sepsis No drug interventions Not Available Not Available unknown_status NCT02367170
Project 4A: Inspiratory Muscle Training and Diaphragm Strength prevention 1 / 2 terminated NCT03777670
nSeP: Detecting Neonatal Sepsis by Immune-Metabolic Network Analysis No drug interventions Not Available Not Available unknown_status NCT02447042
Minimal Volume for a Fluid Challenge in Septic Patients No drug interventions diagnostic Not Available completed NCT00793442
Endothelium in Severe Sepsis No drug interventions Not Available Not Available completed NCT02430142
Microcirculatory Oxygen Uptake in Sepsis No drug interventions Not Available Not Available completed NCT05208242
Strong Albumin Solutions in Patients With Septic Shock treatment 2 / 3 recruiting NCT05681442
Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis No drug interventions treatment 4 recruiting NCT00698542
Evaluation of the Patient Safety Screening Tool (PSST) for Sepsis No drug interventions Not Available Not Available terminated NCT01355042
Studies of Blood DNA in Patients With Severe Infection DYNAMICS No drug interventions Not Available Not Available completed NCT02986542
Comparison of Success Rates of Femoral Artery Catheterization No drug interventions health_services_research Not Available completed NCT02820142
Plasticity and Regeneration of Renal Epithelial Cells No drug interventions Not Available Not Available unknown_status NCT04662242
The Prognostic Impact of Selenium On Critical Surgical Patients treatment 4 completed NCT04322942
Sepsis Prediction by Monocyte Distribution Width and Procalcitonin No drug interventions Not Available Not Available unknown_status NCT05953142
Use of Dobutamine in Patients With Sepsis and Maintained Hypoperfusion After Initial Volemic Resuscitation. treatment 2 not_yet_recruiting NCT03891342
Effect of Fluid Challenge on Glycocalyx No drug interventions treatment Not Available completed NCT03844542
Therapeutic Plasma Exchange in the Treatment of Sepsis Associated Multi-Organ Failure [SAMOF-TPE] No drug interventions treatment Not Available unknown_status NCT02025699
Prospective Study to Characterize Host-pathogen Related Factors in Hospitalized and ED Patients With LRTI and/or Sepsis No drug interventions Not Available Not Available completed NCT01157299
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO No drug interventions Not Available Not Available unknown_status NCT05179499
Early Vasopressors in Sepsis treatment 3 recruiting NCT05386199
The Role of Serotonin in Intensive Care Patients No drug interventions Not Available Not Available recruiting NCT05171699
Effect of Electroacupuncture in Patients With Sepsis Associated Brain Injury No drug interventions treatment Not Available unknown_status NCT02128399
Antimicrobial Stewardship Reduces MDRO Isolates in Critically Ill Patients No drug interventions Not Available Not Available completed NCT04567199
Influence of Cytosorb on Amount of Catecholamine and Mortality in Sepsis No drug interventions Not Available Not Available completed NCT00197899
Low-Dose Endotoxemia and the Acute Phase Response No drug interventions diagnostic Not Available unknown_status NCT03865706
Inulin for Infections in the Intensive Care Unit prevention 2 active_not_recruiting NCT04576806
Physiological Effects of 38°C vs. 22°C Fluid Therapy in Critically Ill Patients No drug interventions treatment Not Available withdrawn NCT04804306
Sepsis Post Market Clinical Utility Simple Endpoint Study - HUMC No drug interventions Not Available Not Available completed NCT01484106
Cardiac Output Monitoring Managing Intravenous Therapy (COMMIT) to Treat Emergency Department Severe Sepsis No drug interventions prevention Not Available completed NCT00299949
Thrombin Generation and Thromboelastography in Non-overt DIC No drug interventions Not Available Not Available terminated NCT06584149
BAR As a Mortality Predictor in Septic AKI No drug interventions Not Available Not Available active_not_recruiting NCT03802136
Multiple Biomarkers in ICU Sepsis Patients No drug interventions Not Available Not Available unknown_status NCT01447836
Indocyanine Clearance Rate and Septic Liver Injury No drug interventions Not Available Not Available unknown_status NCT02920736
Value of Urine sTREM-1 on Early Predicting AKI in Sepsis No drug interventions Not Available Not Available unknown_status NCT06498336
miRNA in Septic Acute Kidney Injury No drug interventions Not Available Not Available recruiting NCT05143736
Nasal and Gut Microbiota Combined Clinical Events Predicts the Prognosis of Septic Patients No drug interventions Not Available Not Available recruiting NCT02389036
Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients prevention 3 completed NCT04257136
VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients No drug interventions treatment 2 active_not_recruiting NCT05217836
Iron Metabolism Disorders in Patients With Sepsis or Septic Shock. No drug interventions Not Available Not Available unknown_status NCT02697513
The 'Bekele Afessa Scan-Teach-Treat Approach' No drug interventions treatment Not Available unknown_status NCT03214913
Controlled Fluid Resuscitation in Sepsis No drug interventions treatment Not Available unknown_status NCT03803813
Incidence of Sepsis After Craniocerebral Operation No drug interventions Not Available Not Available completed NCT05140213
A STUDY BEFORE/AFTER THE IMPLEMENTATION OF AN ANTI-INFECTIOUS PRESCRIPTION AID No drug interventions Not Available Not Available completed NCT01359813
Albumin Administration in Cirrhotic Patients With Bacterial Infection and a Systemic Inflammatory Response Syndrome Unrelated to Spontaneous Bacterial Peritonitis treatment 3 terminated NCT03252613
Translational Approaches to Septic Cardiomyopathy No drug interventions Not Available Not Available unknown_status NCT04328818
Indwelling Device-associated Biofilms No drug interventions Not Available Not Available active_not_recruiting NCT00987818
Procalcitonin Guided Versus Conventional Antibiotic Therapy in Patients With Sepsis in the ICU No drug interventions treatment Not Available withdrawn NCT02707718
Biomarkers for the Early Identification of Sepsis in the Emergency Department No drug interventions Not Available Not Available completed NCT03440918
Impact of a Procalcitonin Testing and Treatment Algorithm on Antibiotic Use and Outcomes in the Pediatric Intensive Care Unit No drug interventions treatment Not Available completed NCT06329518
Rezafungin Pharmacokinetics in Patients on ECMO other 1 recruiting NCT03924518
Adjunctive Granisetron Therapy in Patients With Sepsis or Septic Shock treatment 2 completed NCT06344819
An Acupuncture Study for People At High Risk for Sepsis No drug interventions treatment 2 recruiting NCT04306419
Observational Trial on Cytokine Adsorption in Sepsis No drug interventions Not Available Not Available recruiting NCT04695119
Sepsis in the ICU-II No drug interventions Not Available Not Available unknown_status NCT05624619
The Diagnostic and Prognostic Value of Speckle Tracking Imaging in Septic Cardiomyopathy No drug interventions Not Available Not Available recruiting NCT02945241
Cystatin-C C-guided Vancomycin Dosing in Critically Ill Patients: A Quality Improvement Project supportive_care 1 completed NCT00371241
Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO No drug interventions Not Available Not Available completed NCT02202941
Procalcitonin-guided Treatment on Duration of Antibiotic Therapy and Cost in Septic Patients No drug interventions treatment Not Available completed NCT06447441
Clinical Outcomes Of Mega-dosage Supplementations Of Cholecalciferol In Critically Ill Patients With Sepsis No drug interventions treatment Not Available not_yet_recruiting NCT03497741
Predictive Value of Procalcitonin for Bacteremia in the ICU No drug interventions Not Available Not Available completed NCT06226441
Aminoglycoside Administration in Septic Patients No drug interventions treatment Not Available recruiting NCT05953441
Artificial Intelligence Versus Human-controlled Doctor in Virtual Reality Simulation for Sepsis Team Training No drug interventions other Not Available completed NCT05807217
A Pharmacokinetics Study of Meropenem and Piperacillin in Patients With Sepsis No drug interventions Not Available Not Available recruiting NCT06440317
Immunothrombosis With Septic Shock Undergoing Renal Replacement Therapy With the OXIRIS Membrane No drug interventions Not Available Not Available recruiting NCT04632017
Computerized Cardiotocography Monitoring of Fetuses With pPROM No drug interventions Not Available Not Available unknown_status NCT02276417
PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors No drug interventions Not Available Not Available active_not_recruiting NCT05283317
Effect of Mesenchymal Stromal Cells on Sepsis and Septic Shock No drug interventions treatment 1 / 2 completed NCT04797117
Analytical Validation of the abioSCOPE Device With a PSP Test: Point-of-Care Precision, Sample Type Comparison and Sample Stability No drug interventions other Not Available completed NCT00229034
Effect of APC and Epo on the Inflammatory Response During Sepsis No drug interventions Not Available Not Available completed NCT00563134
A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult No drug interventions treatment Not Available suspended NCT05448534
Electroencephalographic Patterns of Septic Patients and Its Correlation With Cognitive Outcomes No drug interventions Not Available Not Available completed NCT05273034
Effect of the 1-hour Sepsis Bundle on In-hospital Mortality in Patients With Sepsis in the Emergency Department No drug interventions treatment Not Available completed NCT05312034
Application of an Antimicrobial Stewardship Program in Brazilian ICUs Using Machine Learning Techniques and an Educational Model No drug interventions prevention Not Available unknown_status NCT02120534
Serum CD14 and CD88 Mointoring in ICU No drug interventions Not Available Not Available completed NCT01187134
Medical Education for Sepsis Source Control and Antibiotics No drug interventions other Not Available completed NCT03335124
The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock treatment 4 terminated NCT06338124
Value of Laboratory Biomarkers in Prediction of Outcome in Septic Patients No drug interventions Not Available Not Available recruiting NCT06404424
Combined Hemoperfusion and Therapeutic Plasma Exchange for Treatment of Patients With Septic Shock No drug interventions Not Available Not Available completed NCT05941624
Comparison Between HA330 Hemoperfusion Filter Hemodialysis and Conventional High-Flux Hemodialysis Filter No drug interventions treatment Not Available recruiting NCT00176124
Leukocyte Depletion of Autologous Whole Blood No drug interventions treatment 4 completed NCT02768324
the Effect of Gut Microbiota on the Prognosis of Sepsis No drug interventions Not Available Not Available unknown_status NCT05314816
Rapid Blood Culture Identification Panel in Pediatric Patients in Guatemala No drug interventions diagnostic Not Available completed NCT00750516
Lactic Acid Levels In Hypotensive Patients Without(Standard) and With Tourniquet No drug interventions Not Available Not Available withdrawn NCT05842616
Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy: No drug interventions treatment Not Available completed NCT06375616
Comparison of Nafamostat and Unfractionated Heparin in RRT for Sepsis Associated AKI treatment 4 not_yet_recruiting NCT05496816
Coagulation Disturbances in COVID-19 Septic Patients No drug interventions Not Available Not Available completed NCT02068716
Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery No drug interventions Not Available Not Available completed NCT00518596
Prevention of Infection in Indian Neonates - Phase II Probiotics Study No drug interventions prevention 2 completed NCT03817996
Fluid Responsiveness in HFNC Patients No drug interventions Not Available Not Available completed NCT05608096
European Registry for Hemadsorption in Sepsis With the Seraph Filter No drug interventions Not Available Not Available recruiting NCT03379896
Study on Antigen-presenting Function of Gamma Delta T Cells in Sepsis and Its Molecular Mechanisms No drug interventions Not Available Not Available unknown_status NCT00605696
Early Insulin and Development of ARDS prevention 2 completed NCT01618396
Effects of Sedatives on Sublingual Microcirculation of Patients With Septic Shock treatment Not Available completed NCT03788096
Peer Support for Post Intensive Care Syndrome Self-Management No drug interventions supportive_care Not Available unknown_status NCT05602896
Reducing 30-Day Sepsis Readmissions: Impact of a Post Discharge Education Program No drug interventions prevention Not Available withdrawn NCT00772096
Septic Encephalopathy and Late Cognitive Dysfunction prevention 4 completed NCT03846596
Flow Cytometry Analysis of the Reactive Oxygen Species in Immature Granulocytes in Septic Patient No drug interventions Not Available Not Available terminated NCT02189096
Validation of Early Warning Score & Lactate in Prehospital Screening No drug interventions Not Available Not Available completed NCT01807858
The Effects of Synbiotics on Morbidity and Mortality in Preterm Infants No drug interventions prevention Not Available unknown_status NCT03378258
Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA. No drug interventions Not Available Not Available completed NCT01450358
Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture. No drug interventions diagnostic 4 completed NCT04819035
Sepsis Post Market Clinical Utility Simple Endpoint Study - Indiana University Hospital No drug interventions Not Available Not Available completed NCT04304235
Paediatric Rapid Sepsis Trigger (PRST) Tool No drug interventions prevention Not Available completed NCT05361135
18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in S. Aureus Bacteraemia No drug interventions diagnostic Not Available not_yet_recruiting NCT02589535
Circulating Stem Cells, SDF-1, HIF-1 and Sepsis's Indices in Emergency Abdominal Surgical Patients No drug interventions Not Available Not Available unknown_status NCT04995835
Cefiderocol PK in Patients on ECMO other 1 recruiting NCT06219135
Evaluation of the Performance of the IDBIORIV Method in Pathogen Identification and Antibiotic Susceptibility Testing in Patients With Sepsis No drug interventions Not Available Not Available recruiting NCT04059263
HFIP Ex-vivo Study No drug interventions Not Available Not Available completed NCT01948063
Ubiquinol (Reduced COQ10) for Patients With Sepsis other 2 completed NCT03131063
Pharmacokinetic Study of Antibiotics in Patients Assisted by Extracorporeal Membrane Oxygenation (PHARMECMO) No drug interventions Not Available Not Available completed NCT00089986
GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults treatment 2 completed NCT02370186
The Role of Dysfunctional HDL in Severe Sepsis No drug interventions Not Available Not Available completed NCT03306186
Hemospec Device for the Diagnosis of Sepsis No drug interventions diagnostic Not Available completed NCT00347386
Therapeutic Zinc in Infant Bacterial Illness treatment 2 / 3 completed NCT00511186
A Study in Sepsis Patients With Renal Failure No drug interventions treatment 2 terminated NCT00854386
Effect of Intraoperative Fluid Restriction on Postoperative Outcomes in Video-assisted Thoracic Surgery (VATS) No drug interventions treatment Not Available unknown_status NCT01801839
Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients No drug interventions Not Available Not Available completed NCT05595239
Blood Purification in Septic Children No drug interventions treatment Not Available not_yet_recruiting NCT04335539
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants treatment 2 completed NCT04823039
Vaccine Response in Patient With Sepsis No drug interventions prevention Not Available completed NCT04825639
Identifying Risk Factors for Developing AKI in Sepsis No drug interventions Not Available Not Available completed NCT00561639
Benefit of SeptiFast Multiplex PCR in the Etiologic Diagnosis and Therapeutic Approach for Onco-hematology Patients Presenting Sepsis No drug interventions Not Available Not Available completed NCT00174122
Procalcitonin in Diagnosing Bacteremia in the Emergency Department No drug interventions Not Available Not Available unknown_status NCT06178822
Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room No drug interventions Not Available Not Available recruiting NCT04898322
SY-005 （Recombinant Human Annexin A5）in Patients With Sepsis No drug interventions treatment 2 unknown_status NCT05770622
Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2) No drug interventions treatment 4 not_yet_recruiting NCT01459822
MiRNAs Evaluate the Prognosis of Sepsis by Dynamic Study No drug interventions Not Available Not Available unknown_status NCT04067622
Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment No drug interventions treatment Not Available completed NCT05565222
Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit treatment 3 recruiting NCT00222222
Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis No drug interventions diagnostic Not Available completed NCT00850122
An Open Label Study to Describe the Pharmacokinetics of Cefazolin in Preterm Neonates treatment 1 completed NCT02186522
Immune Failure in Critical Therapy (INFECT) Study No drug interventions Not Available Not Available completed NCT02679625
Comparison of Non-Invasive Methods of Assessing Fluid Responsiveness in ED and ICU Patients No drug interventions Not Available Not Available completed NCT03332225
A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis treatment 2 completed NCT03208725
Childhood Acute Illness and Nutrition Network No drug interventions Not Available Not Available unknown_status NCT06210425
Is Re-examination of Urine Culture Necessary for Patients With Preoperative Positive Results in Predicting Infectious Complications Related to Mini-Percutaneous Nephrolithotomy? No drug interventions Not Available Not Available recruiting NCT05985525
Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS) No drug interventions Not Available Not Available recruiting NCT01838525
Alpha-1-acid Glycoprotein as a Biomarker of Developmental Diagnosing and Monitoring Effectiveness in Sepsis No drug interventions Not Available Not Available unknown_status NCT04870125
Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS) treatment 1 active_not_recruiting NCT04611425
REmimazolam Infusion in the Context of Hypnotic Shortage in the Critical Care Unit During the Pandemic of COVID-19: REHSCU Study supportive_care 2 completed NCT02755025
Clinical Score Usefulness and EHR Integration No drug interventions Not Available Not Available completed NCT03372330
Peripheral Artery Disease and Sepsis Outcomes No drug interventions Not Available Not Available unknown_status NCT06045130
PUFAs in Preterm Infants No drug interventions Not Available Not Available not_yet_recruiting NCT03278730
Efficacy of Para-Tyrosine Supplementation on the Survival and Clinical Outcome in Patients With Sepsis prevention 2 not_yet_recruiting NCT06072430
A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02) No drug interventions treatment 3 recruiting NCT02195830
Inferior Vena Cava Collapsibility Index in Severe Sepsis No drug interventions diagnostic Not Available unknown_status NCT05265130
The Efficacy of YiQiFuMai Injection as an Adjunctive Treatment for Sepsis No drug interventions treatment 4 not_yet_recruiting NCT00067730
A Safety Evaluation of Drotrecogin Alfa (Activated) in Patients With Blood Cancer, Severe Infection Related to Bone Marrow Transplantation treatment 4 completed NCT01818830
Amino Acids Expression Profiling of Patients With Sepsis No drug interventions Not Available Not Available unknown_status NCT02203630
Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients treatment 4 terminated NCT02370030
Effect of Citrulline on the Clinical and Biochemical Evolution of Patients With Sepsis. No drug interventions treatment 1 / 2 unknown_status NCT03644030
Phase Angle, Lean Body Mass Index and Tissue Edema and Immediate Outcome of Cardiac Surgery Patients No drug interventions Not Available Not Available completed NCT04300530
Monocyte Distribution Width (MDW) in Hospital Practice No drug interventions Not Available Not Available unknown_status NCT00916448
The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia treatment Not Available completed NCT06241248
Evaluation of the Performance of a New Rapid Bacteremia Test in the Intensive Care Patient No drug interventions Not Available Not Available recruiting NCT01847248
HSPA12B as a Potential Biomarker for Sepsis and Severe Sepsis No drug interventions Not Available Not Available completed NCT02846948
The Impact of Focused Transthoracic Echocardiography in Urgent Abdominal Surgery for Septic Patients No drug interventions treatment Not Available completed NCT02285257
Epidemiology of Sepsis at Yuetan Subdistrict in Beijing No drug interventions Not Available Not Available unknown_status NCT04748757
Annexin A5 in Patients With Severe COVID-19 Disease No drug interventions treatment 2 completed NCT03754257
Effects of Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis No drug interventions treatment Not Available recruiting NCT01333657
The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney Injuries No drug interventions Not Available Not Available completed NCT03441126
Blood Culture Improvement Guidelines and Diagnostic Stewardship for Antibiotic Reduction in Critically Ill Children No drug interventions Not Available Not Available completed NCT03226626
Tumescent Anesthesia Antibiotic Delivery (TAAD) No drug interventions prevention 2 / 3 unknown_status NCT01197326
The Prevention of Failure to Rescue Using Early Warning Scoring No drug interventions Not Available Not Available completed NCT04644926
The Effect of Remote Ischemic Conditioning on the Microcirculation in Sepsis No drug interventions treatment 1 / 2 completed NCT03655626
Implementation and Evaluations of Sepsis Watch No drug interventions treatment Not Available completed NCT06323226
The Impact of Sepsis on Long-term Outcomes in Critical Ill Children With Sepsis No drug interventions Not Available Not Available recruiting NCT04079426
Tetracycline to Limit the Innate Immune Response in Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available unknown_status NCT03859726
Predictive Value of Sublingual Microcirculation and Peripheral Tissue Oxygen Monitoring No drug interventions Not Available Not Available completed NCT03881566
Presepsin as Detective Marker of Sepsis in Immunodeficiency ICU Patients No drug interventions Not Available Not Available completed NCT02276066
Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS No drug interventions diagnostic Not Available completed NCT01493466
Serum Proteomics Analysis for Sepsis No drug interventions Not Available Not Available unknown_status NCT01174966
Assessment of Transcutaneous Oxygen Tension/Oxygen Challenge Test in Intensive Care Unit (ICU) Patients No drug interventions Not Available Not Available unknown_status NCT03791866
The Th9/IL-9 and Early Enteral Nutrition in Sepsis No drug interventions treatment Not Available unknown_status NCT04791566
Preoperative High-dose Dexamethasone and Emergency Laparotomy treatment 4 completed NCT03226366
Effect of Emergency Department Care Reorganization on Door-to-antibiotic Times for Sepsis (LDS SWARM) No drug interventions Not Available Not Available completed NCT01653665
Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? basic_science 1 / 2 completed NCT05024565
Prolonged Intravenous Infusion of β-lactam Antibiotics in Early Septic Patients No drug interventions treatment Not Available unknown_status NCT00321165
The AOT (Acridine Orange and Taurolidine) Trial prevention 3 completed NCT02319265
Dose Assessment of Melatonin in Sepsis Trial treatment 1 / 2 withdrawn NCT04049565
CRP Versus PCT as Bio-markers for Sepsis and in Guiding Antibiotics in Critically Ill Patients No drug interventions Not Available Not Available completed NCT00835874
Probiotic Administartion to Mothers of Preterm Infants to Prevent Necrotizing Enterocolitis and Sepsis No drug interventions prevention Not Available terminated NCT03892174
Cytokine REmoval in CRitically Ill pAtients Requiring Surgical Therapy for Infective Endocarditis (RECReATE) No drug interventions treatment Not Available recruiting NCT03680274
Lessening Organ Dysfunction With VITamin C treatment 3 completed NCT01155674
Innate Immune Functions of Immature Neutrophils No drug interventions Not Available Not Available unknown_status NCT02887274
Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis No drug interventions Not Available Not Available unknown_status NCT00297674
Intravenous Clarithromycin in Septic Syndrome treatment 4 completed NCT05095220
Integration of NAVOY® Sepsis in an Electronic Health Record System No drug interventions Not Available Not Available completed NCT00780520
The Effect of Glutamine on Systemic Inflammation During Human Experimental Endotoxemia No drug interventions basic_science Not Available completed NCT05610020
Heparin Binding Protein as a Prognostic Biomarker of Sepsis Severity No drug interventions Not Available Not Available completed NCT01362920
Diagnostic and Prognostic Value of Serial Procalcitonin (PCT) Measurements in Critically Ill Patients No drug interventions Not Available Not Available completed NCT03756220
Ascorbic Acid and Thiamine Effect in Septic Shock treatment 2 completed NCT00818220
Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants No drug interventions prevention 2 completed NCT03996720
Early Identification and Effective Management of Pediatric Sepsis No drug interventions Not Available Not Available completed NCT01790620
Impact of CVVHD With Adsorption Capacity Membranes in Septic Acute Kidney Injury No drug interventions supportive_care Not Available completed NCT05997420
Adapting a Sepsis Transition and Recovery Program for Optimal Scale Up No drug interventions health_services_research Not Available recruiting NCT01801020
Different Modes of Temperature Measurement in the Emergency Department No drug interventions diagnostic 3 withdrawn NCT05999682
Improvement of Organ Function by Apigenin in Elderly Patients With Sepsis No drug interventions treatment 1 / 2 completed NCT01315782
Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis No drug interventions Not Available Not Available recruiting NCT06080282
Role of the Kallikrein-kinin System in Septic Cardiomyopathy No drug interventions Not Available Not Available recruiting NCT04843982
Immunoinflammatory Regulation of Esketamine in Septic Patients treatment 4 recruiting NCT02024282
Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care No drug interventions diagnostic Not Available completed NCT03497182
Sepsis, Severe Sepsis and Septic Shock Detection by Breath Analysis No drug interventions diagnostic Not Available completed NCT04698382
Impact of COVID-19 on the Incidence, Characteristics, Management and Outcome of Sepsis No drug interventions Not Available Not Available withdrawn NCT02340182
The Role of the Microbiota in the Systemic Immune Response basic_science Not Available completed NCT01333982
Neonatal Sepsis, Evaluation, Bangladesh No drug interventions health_services_research Not Available completed NCT01207531
MiRNAs Evaluate the Prognosis of Sepsis No drug interventions Not Available Not Available unknown_status NCT04166331
Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion treatment 3 recruiting NCT00545831
Effect of Taurolidin on Prevention of Bloodstream Infection No drug interventions prevention Not Available terminated NCT04292431
Leukocyte MOrphology and CORticosteroids Response in SEPtic Patients (MOCORSEP) No drug interventions Not Available Not Available completed NCT05849831
Optic Nerve Sheath Diameter for Prediction of Sepsis Associated Encephalopathy No drug interventions Not Available Not Available completed NCT03604731
Persistent Multiorgan Failure in Intensive Care Units No drug interventions Not Available Not Available completed NCT00318331
Enteral Glutamine in Critical Illness treatment 2 / 3 terminated NCT02907931
Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status No drug interventions diagnostic Not Available completed NCT01214473
Probiotics for Prevention Neonatal Infection No drug interventions prevention Not Available terminated NCT04470973
Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients. Not Available Not Available unknown_status NCT00457873
Isotonic Versus Hypotonic Fluid for Maintenance IV Therapy treatment 3 completed NCT04542473
Pancreatic Enzymes and Bile Acids in Acutely Ill Severely Malnourished Children prevention 2 / 3 active_not_recruiting NCT05606627
Correlation Between Antibiotic Resistance and Incidence of Sepsis in Community Acquired Pneumonia No drug interventions Not Available Not Available not_yet_recruiting NCT03509727
Procalcitonin in Diagnosis of Bacterial Infections in Young Infants No drug interventions Not Available Not Available completed NCT00736827
BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients No drug interventions Not Available Not Available completed NCT00427076
Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections treatment 3 completed NCT04940676
Oral Administration or Nasal Feeding of Huzhangxiefei Decoction for Treatment in Sepsis Induced Acute Lung Injury No drug interventions treatment 2 unknown_status NCT04160676
Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis treatment Not Available completed NCT03280576
Validation of Progranulin as a Biomarker for Sepsis No drug interventions Not Available Not Available completed NCT05524376
Regulatory Network and Diagnostic Value of Key Autophagy-related Genes in Sepsis No drug interventions Not Available Not Available unknown_status NCT02002676
Prevalence and Outcome of Hypermetabolism in Initial Prevalence and Outcome of Hypermetabolism in Initial Phase of Intensive Care Unit Patient: a Prospective Observational Study No drug interventions Not Available Not Available unknown_status NCT04137276
Effect of Intravenous Vitamin C on SOFA Score Among Septic Patients supportive_care Not Available completed NCT01275976
Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture treatment 3 terminated NCT00616876
Lactulose Supplementation in Premature Infants prevention 2 completed NCT02073760
Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2 No drug interventions Not Available Not Available completed NCT03720860
Inflammatory Mediators of Acute Kidney Injury in Intensive Care No drug interventions Not Available Not Available recruiting NCT02929160
Percutaneous Nephrostomy Versus Stent In Sepsis Trial No drug interventions treatment Not Available withdrawn NCT05136560
Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis treatment 1 / 2 recruiting NCT04078594
Electronic Early Notification of Sepsis in Hospitalized Ward Patients No drug interventions screening Not Available completed NCT00524394
Characteristics of Cord Blood Immunologic Parameters of Infants <32 Weeks Gestation No drug interventions Not Available Not Available terminated NCT01382394
Impact of Clinical, Demographic and Laboratory Variables on Brain Natriuretic Peptide Levels No drug interventions Not Available Not Available withdrawn NCT06001294
We Collected Blood Samples From Septic Shock Patients and Measured ELABELA, Creatinine, and NGAL Levels. Survival After 7 Days Was Recorded and Analyzed to Evaluate the Potential of Serum ELABELA as an Early Diagnostic Marker for Sepsis-associated Acute Kidney Injury. No drug interventions Not Available Not Available recruiting NCT05151094
Registry of Hospitalized Patients in University Hospital Dubrava Respiratory Center No drug interventions Not Available Not Available active_not_recruiting NCT02796794
Effect of Enteral Genistein Supplementation in Sepsis No drug interventions treatment 4 unknown_status NCT05759494
The Clinical and Pharmacoeconomic Impact of Rapid Diagnostic Test (Multiplex PCR FilmArray) on Antimicrobial Decision Making Compared to Conventional Decision Making Among Critically Ill Patients No drug interventions Not Available Not Available not_yet_recruiting NCT00808691
Microcirculation and Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit No drug interventions Not Available Not Available completed NCT04088591
High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda treatment 3 withdrawn NCT01359891
Clinical Evaluation of Novel Biomarkers in Patients With Septicemia No drug interventions Not Available Not Available completed NCT06231862
Gene Expression Objective Definition of Early Sepsis In Children No drug interventions Not Available Not Available completed NCT04968262
Urinary Actin, as a Potential Marker of Sepsis-related Acute Kidney Injury No drug interventions Not Available Not Available completed NCT05908162
Algorithm for Predicting the Unfavorable Course of Sepsis in Children No drug interventions Not Available Not Available recruiting NCT00615862
Relationship Between Alcohol Use Disorders and Cortisol Levels in Patients With Sepsis No drug interventions Not Available Not Available completed NCT03841162
Fast Assay for Pathogen Identification and Characterization No drug interventions Not Available Not Available completed NCT04199962
Genomics in Infection and Sepsis to Predict Organ Dysfunction and Outcomes in Sepsis No drug interventions Not Available Not Available unknown_status NCT01029080
Cerebrovascular Autoregulation During Sepsis No drug interventions Not Available Not Available completed NCT04961580
PK/PD of Ceftazidime Avitbatan Sodium in Children With Severe Infection Not Available Not Available recruiting NCT00346580
The Effects of HIV Protease Inhibitors in Severe Sepsis treatment 1 completed NCT00811980
The Effects of Linezolid and Vancomycin on Inflammation and Cellular Signaling Vents Not Available Not Available completed NCT04580680
Extracorporeal Blood Purification Therapy in Critically Ill Patients (GlobalARRT) No drug interventions Not Available Not Available recruiting NCT05914480
Sepsis in ICU:Causes and Outcomes in Diabetics and Non Diabetics No drug interventions Not Available Not Available not_yet_recruiting NCT06045780
HO-1/CREB3 Modulates Golgi Stress in Patients With Sepsis No drug interventions Not Available Not Available recruiting NCT06076980
Heamodynamic Effects of Paracetamol in Septic Shock Patients other 4 completed NCT06193980
Exercise Testing in ICU Survivors to Evaluate ICU-acquired Weakness No drug interventions Not Available Not Available recruiting NCT05186480
Evaluation of the Effect of Immune Modulating Enteral Nutrition Formula No drug interventions supportive_care Not Available unknown_status NCT04033029
Antibiotic Plasma Concentrations During Continuous Renal Replacement Therapy With a High Adsorption Membrane (oXiris®) Not Available Not Available completed NCT01906229
Lung and Systemic Inflammation in the Critically Ill Patient No drug interventions Not Available Not Available terminated NCT04217629
Single-dose/Multiple-doses Incremental Intravenous Injection of SY-005 （Recombinant Human Annexin A5）in Healthy Subjects No drug interventions treatment 1 completed NCT04771429
A Machine Learning Predictive Model for Sepsis No drug interventions Not Available Not Available unknown_status NCT01362829
Outcome Predictors in Patients With Severe Sepsis and Optimized Central Venous Oxygen Saturation No drug interventions Not Available Not Available completed NCT06220929
Mecobalamin Combined With Ceftriaxone Sodium in the Treatment of Sepsis Liver Injury treatment 4 not_yet_recruiting NCT05459389
Early Targeted Antibiotic Therapy in Patients With Sepsis No drug interventions treatment Not Available completed NCT05194189
Clinical Efficacy of Megadose Vitamin C in Sepsis treatment 2 recruiting NCT04904289
Early Recognition and Dynamic Risk Warning System of Multiple Organ Dysfunction Syndrome Caused by Sepsis No drug interventions Not Available Not Available unknown_status NCT04759989
Fluid Resuscitation in Septic Shock Patients With BMI Elevation No drug interventions treatment Not Available terminated NCT04148989
Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care No drug interventions health_services_research Not Available completed NCT05391789
Clinical Efficacy of Ulinastatin for Treatment of Sepsis With Systemic Inflammatory Response Syndrome treatment 3 unknown_status NCT00739089
Presep and Vascath Interaction Study No drug interventions Not Available Not Available withdrawn NCT00711789
Angiotensin in Septic Kidney Injury Trial treatment 2 unknown_status NCT04945889
Sepsis in Geriatric Patients With Suspected Infection. No drug interventions Not Available Not Available completed NCT05309889
A Prospective Observational Study of Sepsis No drug interventions Not Available Not Available unknown_status NCT01139489
Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's) No drug interventions treatment Not Available completed NCT01494389
The Changes of CD4+T Lymphocyte Subsets in Septic Patients No drug interventions Not Available Not Available unknown_status NCT06068192
Registration of Sepsis Patients in the Emergency Department No drug interventions Not Available Not Available not_yet_recruiting NCT03178292
Conventional Antibiotic Prophylaxis Versus Add-On 5 Days Levofloxacin Before Percutaneous Nephrolithotomy treatment Not Available unknown_status NCT06516692
Inferior Vena Cava Collapsibility and Distensibility Assessment in Critical Care. No drug interventions diagnostic Not Available recruiting NCT06150092
Use of Presepsin in the Emergency Department No drug interventions Not Available Not Available recruiting NCT03388944
PCT Guided Stopping of Antibiotic Therapy in Children With Sepsis No drug interventions supportive_care Not Available completed NCT01760044
Noninvasive Assessment of Tissue Perfusion Status in Critically Ill Pediatric Patients No drug interventions device_feasibility Not Available completed NCT04724044
Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia treatment 3 completed NCT02871544
Predictive Value of Dynamic Combination of BNP and NGAL for the Prognosis of Patients With Sepsis No drug interventions screening Not Available completed NCT00396344
Cortisol Control of Human Inflammatory Responses to Endotoxin Not Available Not Available completed NCT05784740
Precision Exercise to Improve Outcomes in Sepsis No drug interventions other Not Available recruiting NCT03644940
Subpopulation-Specific Sepsis Identification Using Machine Learning No drug interventions diagnostic 2 withdrawn NCT03488940
Effect of Different Feeding Method on Gastrointestinal Function of Septic Patients (DFM-GF Trial) No drug interventions treatment Not Available withdrawn NCT04582240
Bile Duct Injury Digestif No drug interventions Not Available Not Available completed NCT04549740
The Role of Salivary Alpha Amylase in Sepsis No drug interventions Not Available Not Available completed NCT01649440
Sepsis Metabolomics No drug interventions Not Available Not Available completed NCT00781040
Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients No drug interventions Not Available Not Available completed NCT04397640
Myocardial Contrast Echocardiography in Septic Patients No drug interventions diagnostic Not Available unknown_status NCT01760967
Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial treatment 4 completed NCT02867267
The Efficacy and Safety of Ta1 for Sepsis treatment 3 completed NCT03525067
Colonization of Bile Ducts and Postoperative Infectious Complications of Pancreaticoduodenectomies No drug interventions Not Available Not Available completed NCT00874367
Early-Onset Sepsis Surveillance Study No drug interventions Not Available Not Available completed NCT04979767
Function of Circulating Exosomes in Sepsis-induced Immunosuppression No drug interventions Not Available Not Available unknown_status NCT03931967
Proadrenomedullin and Microcirculation in Monitoring Organ Dysfunction in Patient With Infection No drug interventions Not Available Not Available completed NCT01663701
Simplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia No drug interventions treatment Not Available completed NCT04647201
Study of Biomarkers in Patients of Sepsis Complicated With Gastrointestinal Dysfunction No drug interventions Not Available Not Available unknown_status NCT03392701
Possible Links Between Inflammation and Lipid Metabolism No drug interventions basic_science Not Available completed NCT04571801
Optimization of Sepsis Therapy Based on Patient-specific Digital Precision Diagnostics No drug interventions diagnostic Not Available unknown_status NCT02266901
Transluminal or Percutaneous Endoscopic Drainage and Debridement of Abcesses After Bariatric Surgery No drug interventions Not Available Not Available completed NCT05748301
AI Clinician XP2 - A Study of the AI Clinician Running in Real Time in the ICU No drug interventions Not Available Not Available not_yet_recruiting NCT03333304
A Clinical Trial of Procalcitonin-guided Antimicrobial Therapy in Sepsis No drug interventions treatment Not Available completed NCT00880204
Evaluation of Essential Surgical Skills-Emergency Maternal and Child Health Training No drug interventions other Not Available completed NCT03876704
Effects of Fat-soluble Vitamins Supplementation on Common Complications and Neural Development in Very Low Birth Weight Infants No drug interventions treatment 3 unknown_status NCT03953404
POC SPLA2-IIA as a Biomarker for Sepsis and Septic Shock No drug interventions Not Available Not Available unknown_status NCT06181604
Multicenter Symphony IL-6 Monitoring Sepsis ICU Study No drug interventions Not Available Not Available active_not_recruiting NCT01379404
Bioimpedance Analysis in Septic Intensive Care Unit (ICU) Patients No drug interventions Not Available Not Available completed NCT05718804
Gut Microbiota and Sepsis-associated Acute Kidney Injury No drug interventions Not Available Not Available not_yet_recruiting NCT05639504
Sepsis Prognosis and Diagnosis in the Emergency Department (SPEED) No drug interventions Not Available Not Available withdrawn NCT02448472
Epidemiology of Sepsis in China No drug interventions Not Available Not Available completed NCT06280872
Physiologically Based Cord Clamping To Improve Neonatal Outcomes In Moderate And Late Preterm Newborns No drug interventions treatment Not Available recruiting NCT02365272
Pharmacokinetic/Pharmacodynamic Evaluation Amikacin in Critically Ill Patients Admitted at the Emergency Department treatment 4 completed NCT02508272
Transcriptomic Profiling in Severely Injured Patients No drug interventions Not Available Not Available completed NCT00304772
Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients treatment 4 withdrawn NCT06156072
Ultrasound-guided Blood Sampling Drawing for Microbiological Analysis in the Critically Ill No drug interventions Not Available Not Available not_yet_recruiting NCT03788772
Systems Analysis of Antigen Presenting Cells in Human Sepsis No drug interventions basic_science Not Available unknown_status NCT01828372
Quantification of Drugs and Their Degradation Products No drug interventions screening Not Available unknown_status NCT01423968
Effect of Lipopolysaccharide on Skeletal Muscle Functions No drug interventions basic_science Not Available completed NCT01878968
Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes? No drug interventions health_services_research Not Available completed NCT04103268
Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis No drug interventions Not Available Not Available recruiting NCT06209268
The Impact of Selective Vitamin D Receptor Activation on Clinical Outcomes in Septic Patients treatment Not Available not_yet_recruiting NCT05082168
Capnodynamic Monitoring of Cardiorespiratory Function in Critically Ill Patients No drug interventions Not Available Not Available unknown_status NCT04117568
The Role of Emergency Neutrophils and Glycans in Postoperative and Septic Patients No drug interventions Not Available Not Available terminated NCT02730468
SEP-SEQ Trial - Determining the Etiology of Sepsis Using an Infectious Disease Diagnostic Sequencing Assay No drug interventions Not Available Not Available completed NCT01169168
Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome (SIRS), Sepsis or Chronicle Liver Disease on Intensive Care Units (ICU) No drug interventions Not Available Not Available unknown_status NCT01903668
Determination of the Nature of the Endogenous Ligand of TREM-1 and Its Use as a New Diagnostic Biomarker in Sepsis No drug interventions Not Available Not Available withdrawn NCT04127968
Efficacy and Safety of Vitamin A Treatment for Children With Sepsis treatment Not Available unknown_status NCT03645668
Efficacy and Pharmacokinetics of Meropenem in Severe Septic Patients treatment 4 completed NCT03523169
Cerebral Oxygen Challenge of Passive Leg Raising Test in Sepsis No drug interventions Not Available Not Available completed NCT04963569
Mechanistic Inflammatory Sub-study Embedded Within the Albumin vs Balanced Crystalloid Trial No drug interventions Not Available Not Available completed NCT05246969
Detecting Sepsis in Patients With Severe Subarachnoideal Hemorrhage No drug interventions Not Available Not Available completed NCT04989569
Serial Body Composition Change for Risk Prediction and Nutritional Guide in Treating Patients With Sepsis No drug interventions supportive_care Not Available completed NCT01378169
SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU No drug interventions Not Available Not Available completed NCT01140269
Rapid Detection of Staphylococcus Aureus in Burn Patients No drug interventions diagnostic Not Available completed NCT03473769
Sepsis Pre-Alert Monitoring Intervention: Study to Investigate Targeted Enhanced Monitoring for Sepsis No drug interventions prevention Not Available not_yet_recruiting NCT03338569
Vitamin C and Septic Shock treatment 2 / 3 completed NCT03146546
STUDY00015328: Sepsis Endotypes No drug interventions Not Available Not Available enrolling_by_invitation NCT04568746
Implementation of a qSOFA Score in the Emergency Department No drug interventions screening Not Available unknown_status NCT03433846
Predictors of Sepsis in Ex-Preterm Infants No drug interventions Not Available Not Available completed NCT05758246
Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial treatment 2 recruiting NCT05311046
Biomarker-enhanced Artificial Intelligence Based Pediatric Sepsis Screening Tool No drug interventions Not Available Not Available recruiting NCT03253146
The Role and Mechanism of Vimentin in Sepsis Patients No drug interventions Not Available Not Available unknown_status NCT04508946
Triple Therapy in Septic Shock Patients treatment 3 completed NCT03249246
Epidemiology of Sepsis in Turkish ICUs. No drug interventions Not Available Not Available completed NCT03363646
Italian National Study on the Critically Ill Liver Transplant Patient With an Infection No drug interventions Not Available Not Available unknown_status NCT01968746
The AVERT Sepsis Investigation No drug interventions Not Available Not Available completed NCT04495946
Implementation and Effectiveness of Engagement and Collaborative Management to Proactively Advance Sepsis Survivorship No drug interventions health_services_research Not Available completed NCT05018546
Safety and Efficacy of Different Irrigation System in Retrograde Intrarenal Surgery No drug interventions health_services_research Not Available completed NCT03289312
Dissecting How Peripheral Lymphocytes Are Lost During Sepsis No drug interventions Not Available Not Available unknown_status NCT05833412
Molecular Early Sepsis Identification Study No drug interventions Not Available Not Available recruiting NCT04110912
Improving Outcomes After Time Sensitive Prehospital Interventions: Rescu Epistry No drug interventions Not Available Not Available withdrawn NCT01793012
Drug Monitoring of Antibiotics in Critical Care Patients No drug interventions Not Available Not Available completed NCT04169412
Resuscitation Failure, Oxidative Stress, and Necroptosis as Mortality Predictor in Septic Patient No drug interventions Not Available Not Available completed NCT04985110
Administration of Antibiotic Prophylaxis for Transperineal Prostate Biopsy in Cipto Mangunkusumo Hospital treatment 2 unknown_status NCT04872010
Construction of a Database for the Life-cycle Sepsis-specific Disease Cohort No drug interventions Not Available Not Available unknown_status NCT06481410
Efficacy and Safety of Methylene Blue in the Treatment of Severe Septic Shock treatment Not Available not_yet_recruiting NCT05133310
Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia treatment 4 unknown_status NCT02605681
Midkine and ACE-Ang II Induced Endothelial Injury in Sepsis No drug interventions Not Available Not Available completed NCT03877081
Effect of Probiotics and Prebiotics in Renal Function in Septic Acute Kidney Injury Patients No drug interventions treatment 3 unknown_status NCT03037281
Release of Nociceptin From Granulocytes in Sepsis No drug interventions Not Available Not Available completed NCT04103281
Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis No drug interventions Not Available Not Available recruiting NCT03817281
Collective Accuryn Physiologic Signals and Signatures No drug interventions Not Available Not Available withdrawn NCT04513795
EARLY-MYO-SEPSIS Registry No drug interventions Not Available Not Available unknown_status NCT06572995
Thoracic Fluid Content During Stabilization and Therapeutic De-escalation in Septic Shock No drug interventions Not Available Not Available recruiting NCT04516395
Optimizing Antibiotic Dosing Regimens for the Treatment of Infection Caused by Carbapenem Resistant Enterobacteriaceae No drug interventions treatment Not Available unknown_status NCT04747795
Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments treatment 3 completed NCT05874895
MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock No drug interventions treatment Not Available recruiting NCT05453695
Intravenous DNase I for the Treatment of Sepsis (IDEALSepsisI) treatment 1 recruiting NCT02789995
Dysfunctions of Human Muscle Stem Cells in Sepsis No drug interventions basic_science Not Available completed NCT04114214
Objective Sepsis Identification Tool to Study Sepsis Epidemiology No drug interventions Not Available Not Available completed NCT00279214
Hemodynamic and Perfusion Response to Drotrecogin Alfa (Activated) in Patients With Septic Shock treatment 4 completed NCT02295514
Correlation Between PTP1B Expression and Organ Failure During Sepsis No drug interventions Not Available Not Available completed NCT06556914
Effect of Albumin Replacement on Oxygen Delivery in Sepsis Patients No drug interventions Not Available Not Available not_yet_recruiting NCT03807414
Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients No drug interventions Not Available Not Available active_not_recruiting NCT04548414
Homocysteine in Patients With Sepsis No drug interventions Not Available Not Available unknown_status NCT00604214
Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock treatment 3 completed NCT01766414
In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II No drug interventions basic_science 3 completed NCT02682355
Optimizing Clinical Use of Polymyxin B No drug interventions Not Available Not Available completed NCT03389555
Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial treatment 2 / 3 completed NCT04335955
Platelet Indices in Prediction of Mortality in Critically Ill Septic Patients No drug interventions Not Available Not Available completed NCT04529655
Digital Capillary Refill for Monitoring of Sepsis No drug interventions Not Available Not Available unknown_status NCT01756755
Endotoxin Adsorber Hemoperfusion and Microcirculation No drug interventions treatment Not Available completed NCT05807555
Longitudinal Evolution of Biomarkers of Dysautonomia and Inflammation During Sepsis in Children No drug interventions Not Available Not Available recruiting NCT00591955
Infected Elders in the Emergency Department: Outcomes and Processes of Care No drug interventions Not Available Not Available completed NCT00641355
Acute Phase Proteins as Early Markers in Sepsis No drug interventions Not Available Not Available unknown_status NCT03385850
The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis No drug interventions treatment Not Available completed NCT01087450
The Effect of Erythropietin on Microcircualtory Alteration in Intensive Care Unit Patients With Severe Sepsis No drug interventions Not Available Not Available terminated NCT03509350
Vitamin C, Thiamine, and Steroids in Sepsis supportive_care 3 completed NCT00891423
A Study of Meropenem Standard 30 Minute Infusion Versus Prolonged 3 Hour Infusion in Intensive Care Unit (ICU) Patients treatment Not Available completed NCT05213923
ED Tracking Sheet Implementation No drug interventions treatment Not Available completed NCT03309423
Is Venous to Arterial Conversion (v-TAC) of Blood Gas Reliable in Critical Ill Patients in the ICU? No drug interventions Not Available Not Available unknown_status NCT04916223
Study to Determine Therapeutic Massage Dosing to Improve Quality of Life in Hospitalized Patients Receiving Palliative Care No drug interventions treatment Not Available completed NCT06008223
Clinical Analysis of Vitamin B6 in Sepsis treatment Not Available completed NCT00736723
NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock No drug interventions Not Available Not Available completed NCT05033808
Epirubicin for the Treatment of Sepsis & Septic Shock treatment 2 recruiting NCT00452608
Statin for Immunomudulation in Sepsis treatment 2 unknown_status NCT05059808
European Sepsis Care Survey No drug interventions Not Available Not Available completed NCT03133208
Sepsis Associated Encephalopathy (SAE) Biomarkers No drug interventions Not Available Not Available active_not_recruiting NCT01392508
IMproved PREdiction of Severe Sepsis in the Emergency Department No drug interventions Not Available Not Available completed NCT01275638
The Effect of Moderate-Dose Steroid Therapy in Sepsis treatment 4 completed NCT04638738
Outcomes of Digital Alerting Systems in Secondary Care No drug interventions Not Available Not Available unknown_status NCT04728438
Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases No drug interventions Not Available Not Available unknown_status NCT04749238
Effect of Extracorporeal Adsorption of Plasma Neutrophil Extracellular Traps (NET) in Sepsis No drug interventions treatment Not Available completed NCT01601938
Selenium Replacement and Serum Selenium Level in Severe Sepsis and Septic Shock Patients No drug interventions treatment 2 withdrawn NCT04257838
Monitoring of Piperacillin-Tazobactam and Meropenem Plasmatic Levels in Critical Patients Not Available Not Available unknown_status NCT05943938
Comparison of Sepsis Prediction Algorithms No drug interventions Not Available Not Available not_yet_recruiting NCT02338843
A Phase 3 Study of LJPC-501 in Patients With Catecholamine-Resistant Hypotension treatment 3 completed NCT01090115
Study to Look at the Effects of ART-123 on Patients With Sepsis and Disseminated Intravascular Coagulation (DIC) treatment 2 withdrawn NCT02258022
Changes in 13CO2/12CO2 Delta Value in Exhaled Breath as an Early Indicator of Infection in Adult Trauma Subjects No drug interventions Not Available Not Available terminated