Meningitis, Bacterial (DBCOND0060443)
Identifiers
- Synonyms
- Bacterial Meningitis / Meningitis bacterial / Meningitis, bacterial / Bacterial meningitis, unspecified / Meningitis bacterial NOS / Meningitis due to unspecified bacterium / Bacterial meningitis (disorder) / Bacterial meningitis, not elsewhere classified
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Amikacin An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.Ampicillin A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.- Albumincarrier
- Organic cation/carnitine transporter 2transporter
- Solute carrier family 15 member 1transporter
- Solute carrier family 15 member 2transporter
- Penicillin-binding protein 2atarget
- Penicillin-binding protein 1btarget
- Penicillin-binding protein 3target
- Penicillin-binding protein 1Atarget
- Penicillin-binding protein 2Btarget
- Monocarboxylate transporter 1transporter
- Solute carrier family 15 member 1target
- Solute carrier family 15 member 2target
- Angiopoietin-1 receptortarget
Cefepime A fourth-generation cephalosporin antibiotic used in the treatment of infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections.- Organic cation/carnitine transporter 2transporter
- Solute carrier family 15 member 1transporter
- Solute carrier family 15 member 2transporter
- Penicillin-binding protein 2target
- Peptidoglycan synthase FtsItarget
- Cell division proteintarget
- Penicillin-binding protein 2target
- Penicillin-binding protein 1Atarget
- Penicillin-binding protein 1Btarget
- Penicillin-binding protein 1Btarget
Ceftazidime An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others.- Solute carrier family 22 member 6transporter
- Peptidoglycan synthase FtsItarget
- Penicillin-binding protein 1Atarget
- Penicillin-binding protein 1Btarget
- Penicillin-binding protein 2target
- Albumincarrier
- Beta-lactamase Toho-1target
Ceftriaxone A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.- Albumincarrier
- Solute carrier family 15 member 1transporter
- Solute carrier family 15 member 2transporter
- Solute carrier family 22 member 6transporter
- Organic anion transporter 3transporter
- Solute carrier family 22 member 11transporter
- Penicillin-binding protein 2Btarget
- Glutamine synthetaseenzyme
- Solute carrier family 22 member 11target
- Solute carrier family 22 member 6target
- Organic anion transporter 3target
- Solute carrier family 15 member 1target
- ATP-dependent translocase ABCB1transporter
Gentamicin An aminoglycoside used to treat a wide variety of aerobic infections in the body.- 30S ribosomal protein S12target
- 16S ribosomal RNAtarget
- NH(3)-dependent NAD(+) synthetasetarget
- Dihydrofolate reductasetarget
- 23S ribosomal RNAtarget
- Bacterial outer membranetarget
- Cytoplasmic membranetarget
- Low-density lipoprotein receptor-related protein 2transporter
- Solute carrier family 22 member 2transporter
- ATP-binding cassette sub-family C member 2transporter
Meropenem A carbapenem antibiotic used to treat a wide variety of infections in the body.Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body.- Bacterial outer membranetarget
- Solute carrier family 15 member 2transporter
- Dihydropteroate synthasetarget
Tobramycin An aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections.- 16S ribosomal RNAtarget
- Bacterial outer membranetarget
- Cytoplasmic membranetarget
- 23S ribosomal RNAtarget
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT03226379 Driving Reduced AIDS-associated Meningo-encephalitis Mortality No drug interventions health_services_research Not Available completed NCT02274285 DTaP-IPV/Hib Vaccine Primary & Booster Vaccinations Versus Co-administration of DTaP-IPV and Hib Vaccine in Japanese Infants No drug interventions prevention 3 completed NCT01547715 Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Subjects From 2 to 75 Years of Age in India No drug interventions prevention 3 completed NCT03499652 Neonatal Bacterial Meningitis Cohort No drug interventions Not Available Not Available unknown_status NCT05146570 Early Diagnosis of Native and Device-associated Meningitis No drug interventions diagnostic Not Available unknown_status NCT03418441 Central Nervous System Infections in Denmark No drug interventions Not Available Not Available recruiting NCT03891758 Confirmatory Study of BK1310 in Healthy Infants prevention 3 completed NCT01431326 Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care - Alfentanil
- Amikacin
- Aminocaproic acid
- Bosentan
- Cefepime
- Cidofovir
- Ciprofloxacin
- Clozapine
- Fosfomycin
- Haloperidol
- Labetalol
- Lurasidone
- Methylprednisolone
- Molindone
- Nafcillin
- Nifedipine
- Oxycodone
- Pentobarbital
- Piperacillin
- Rocuronium
- Sevelamer
- Spironolactone
- Tazobactam
- Tobramycin
- Tranexamic acid
- Vancomycin
- Vecuronium
- Warfarin
- Ziprasidone
- Zolpidem
Not Available Not Available completed NCT01410474 Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Subjects From 2 to 18 Years in Taiwan No drug interventions prevention 3 completed NCT00774631 IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis No drug interventions treatment 4 terminated NCT01589289 Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC No drug interventions diagnostic 3 completed NCT01540838 Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial Meningitis No drug interventions treatment 4 completed NCT00619203 Oral Glycerol and High-Dose Rectal Paracetamol to Improve the Prognosis of Childhood Bacterial Meningitis No drug interventions treatment 3 completed NCT04771884 Population Pharmacokinetics of Commonly Used Antimicrobial Agents in Children of Bacterial Meningitis With Augmented Renal Clearance No drug interventions Not Available Not Available recruiting NCT03595761 Meningitis With Cerebral Vasculitis in Children No drug interventions Not Available Not Available completed NCT02467309 Vitamin d Levels in Children With Bacterial Meningitis No drug interventions Not Available Not Available unknown_status NCT02979951 Fosfomycin i.v. for Treatment of Severely Infected Patients No drug interventions Not Available Not Available recruiting NCT03252028 Rapid Test for Detection of the Focus of Infection in Post Neurosurgical Patients. No drug interventions Not Available Not Available unknown_status NCT01747369 Surveillance of Hospitalised Pneumonia and Bacterial Meningitis in Tône District, Togo, 2010-2013 No drug interventions Not Available Not Available unknown_status NCT02972281 Systematic Search for Primary Immunodeficiency in Adults With Infections No drug interventions diagnostic Not Available terminated NCT01730690 Bacterial Meningitis in Adults: Analysis of the Determinants of Mortality and Neurosensory Sequelae No drug interventions Not Available Not Available completed NCT04135053 A Controlled Study to Assess Safety, Colonisation and Immunogenicity of Reconstituted Lyophilised Neisseria Lactamica No drug interventions prevention Not Available unknown_status NCT03633474 Defining the Immune Response to Nasopharyngeal Colonisation by the Commensal Neisseria Lactamica No drug interventions prevention 0 completed NCT04196192 Febrile Infants - Diagnostic Assessment and Outcome No drug interventions Not Available Not Available completed NCT03630250 Challenge of the Nasopharynx With Neisseria Lactamica Expressing the Meningococcal Protein Neisseria Adhesin A (NadA) No drug interventions prevention 0 completed