Chronic Schizophrenia

Also known as: Schizophrenia NOS / Schizophrenic disorders / Dementia praecox / Schizophrenia, unspecified / Unspecified schizophrenia / Unspecified schizophrenia, unspecified state / Schizophrenia

DrugDrug NameDrug Description
DB06288AmisulprideA dopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults.
DB00875FlupentixolA thioxanthene neuroleptic used to treat schizophrenia and depression.
DB01621PipotiazineAn antipsychotic indicated for the management of chronic, non-agitated schizophrenic patients.
DB00391SulpirideA selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia.
DB01624ZuclopenthixolAn antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance.
DrugDrug NameTargetType
DB06288AmisulprideDopamine D2 receptortarget
DB06288AmisulprideDopamine D3 receptortarget
DB06288Amisulpride5-hydroxytryptamine receptor 7target
DB06288Amisulpride5-hydroxytryptamine receptor 2Atarget
DB06288AmisulprideErythrocytecarrier
DB06288AmisulprideMultidrug and toxin extrusion protein 1transporter
DB06288AmisulprideMultidrug and toxin extrusion protein 2transporter
DB06288AmisulprideP-glycoprotein 1transporter
DB06288AmisulprideATP-binding cassette sub-family G member 2transporter
DB06288AmisulprideSolute carrier family 22 member 1transporter
DB06288AmisulprideMu-type opioid receptortarget
DB06288AmisulprideDelta-type opioid receptortarget
DB06288AmisulprideKappa-type opioid receptortarget
DB00875FlupentixolAlpha-1A adrenergic receptortarget
DB00875FlupentixolDopamine D2 receptortarget
DB00875FlupentixolDopamine D1 receptortarget
DB00875FlupentixolAromatic-L-amino-acid decarboxylaseenzyme
DB00875Flupentixol5-hydroxytryptamine receptor 2Atarget
DB00875FlupentixolP-glycoprotein 1transporter
DB00875FlupentixolMuscarinic acetylcholine receptor M1target
DB00875FlupentixolLiver carboxylesterase 1enzyme
DB00875FlupentixolDopamine D3 receptortarget
DB00875FlupentixolDopamine D4 receptortarget
DB00875Flupentixol5-hydroxytryptamine receptor 2Ctarget
DB01621PipotiazineCytochrome P450 2D6enzyme
DB01621PipotiazineCytochrome P450 3A4enzyme
DB01621PipotiazineDopamine D2 receptortarget
DB01621PipotiazineDopamine D1 receptortarget
DB01621Pipotiazine5-hydroxytryptamine receptor 2Atarget
DB01621Pipotiazine5-hydroxytryptamine receptor 1Atarget
DB01621PipotiazineSolute carrier family 22 member 1transporter
DB01621PipotiazineSerum albumincarrier
DB01621PipotiazineCytochrome P450 2C19enzyme
DB00391SulpirideDopamine D2 receptortarget
DB00391SulpirideDopamine D3 receptortarget
DB00391SulpirideCholinesteraseenzyme
DB00391SulpirideCarbonic anhydrase 2target
DB00391SulpirideCarbonic anhydrase 3target
DB00391SulpirideSerum albumincarrier
DB00391SulpirideSolute carrier family 22 member 1transporter
DB00391SulpirideSolute carrier family 22 member 2transporter
DB00391SulpirideMultidrug and toxin extrusion protein 1transporter
DB00391SulpirideMultidrug and toxin extrusion protein 2transporter
DB00391SulpirideDopamine D4 receptortarget
DB00391SulpirideSolute carrier family 22 member 3transporter
DB00391SulpirideP-glycoprotein 1transporter
DB00391SulpirideATP-binding cassette sub-family G member 2transporter
DB01624ZuclopenthixolDopamine D1 receptortarget
DB01624ZuclopenthixolDopamine D5 receptortarget
DB01624ZuclopenthixolDopamine D2 receptortarget
DB01624ZuclopenthixolCytochrome P450 2D6enzyme
DB01624ZuclopenthixolAlpha-1A adrenergic receptortarget
DB01624ZuclopenthixolAlpha-2A adrenergic receptortarget
DB01624Zuclopenthixol5-hydroxytryptamine receptor 2Atarget
DB01624ZuclopenthixolHistamine H1 receptortarget
DB01624ZuclopenthixolCytochrome P450 3A4enzyme
DrugDrug NamePhaseStatusCount
DB01267Paliperidone2Completed1
DB09286Pipamperone2Completed1
DB00734Risperidone2Completed1
DB08815Lurasidone3Completed1
DB01043Memantine3Terminated1
DB09140Oxygen3Unknown Status1
DB01224Quetiapine3Completed1
DB00734Risperidone3Terminated1
DB11672Curcumin4Completed1
DB00674GalantamineNot AvailableCompleted1